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Particular danger of melanoma consists in quick metastasizing.\n</p>\n<p style=\"text-align:justify;\">Melanoma development process is still unclear but specialists underline such risk factors as inherited predisposition, UV radiation and nevus injury.\n</p>\n\n   </div>\n\n\n   \n       \n\n<h2>Types of melanoma</h2>\n\n       <i class=\"fa fa-angle-down\"></i>\n   \n   <div class=\"accordion-item-text\">\n  \t \n\n<p style=\"text-align:justify;\">Oncologists classify melanoma according to the level of its invasion (Clark’s scale), thickness (Breslow’s scale), appearance and development scheme.\n</p>\n<p>According to cell types melanoma is divided into:\n</p>\n<ul>\n\t<li>superficial melanoma;</li>\n\t<li>nodular melanoma;</li>\n\t<li>lentigo melanoma;</li>\n\t<li>acral lentiginous melanoma;</li>\n\t<li>spindle cell melanoma.</li>\n</ul>\n\n\n   </div>\n\n\n   \n       \t\n\n<h2>Symptoms of melanoma</h2>\n\n       <i class=\"fa fa-angle-down\"></i>\n   \n   <div class=\"accordion-item-text\">\n  \t\n\n<p style=\"text-align:justify;\">Early stages of melanoma are often asymptomatic. A patient can notice development of a new nevus or change of existing nevus (redness, increase). Later stages comprise weight loss, weakness, increase of lymph nodes, etc.\n</p>\n\n   </div>\n\n\n   \n       \n\n<h2>Diagnostics</h2>\n\n       <i class=\"fa fa-angle-down\"></i>\n   \n   <div class=\"accordion-item-text\">\n  \t\n\n<p style=\"text-align:justify;\">Complex diagnostics of melanoma includes investigation of the patient’s past medical history, examination of suspicious nevus with dermatoscope and of adjusting lymph nodes. Cancer-specific markers blood test and biopsy can be provided for specification of malignant nature of the disease. If a patient refers to a doctor at later stages comprising metastases, CT, PET-CT or MRI are provided to determine the scope and location of metastases.\n</p>\n\n   </div>\n\n\n   \n       \t\n\n<h2>Treatment of melanoma at each stage</h2>\n\n       <i class=\"fa fa-angle-down\"></i>\n   \n   <div class=\"accordion-item-text\">\n  \t \n\n<p style=\"text-align:justify;\">Medical specialists develop individual program for each case considering general health condition of a patient and specifics of the disease.\n</p>\n<p style=\"text-align:justify;\"><strong>Stage 0</strong> involves surgical removal of a tumor. If surgery cannot be performed, topical therapy is applied.\n</p>\n<p style=\"text-align:justify;\"><strong>Stage 1</strong> melanoma treatment includes surgical excision of affected nevus with surrounding skin tissues.\n</p>\n<p style=\"text-align:justify;\">For<strong> stage 2</strong> melanoma treatment doctors provide expanded tumor excision with biopsy of signal lymph node. Some patients receive interferon alpha as adjuvant drug.\n</p>\n<p style=\"text-align:justify;\"><strong>Stage 3</strong> melanoma treatment comprises removal of both tumor and signal lymph node and tumor masses combined with chemo-, beam or combined therapy.\n</p>\n<p style=\"text-align:justify;\">For <strong>stage 4</strong> melanoma treatment doctors apply immune, targeted and chemotherapy. Metastases are removed surgically or by using radiotherapy or medication.\n</p>\n\n   </div>\n\n\n   \n       \t\n\n<h2>Melanoma treatment cost</h2>\n\n       <i class=\"fa fa-angle-down\"></i>\n   \n   <div class=\"accordion-item-text\">\n  \t\n\n<p style=\"text-align:justify;\">Melanoma treatment cost depends on many factors:\n</p>\n<ul>\n\t<li>melanoma type;</li>\n\t<li>size of tumor;</li>\n\t<li>metastases in organism;</li>\n\t<li>necessary diagnostic procedures;</li>\n\t<li>treatment method;</li>\n\t<li>price policy of the hospital in the particular country.</li>\n</ul>\n<p style=\"text-align:justify;\">Each melanoma patient receives individual diagnostic and treatment program comprising all these factors.\n</p>\n\n   </div>"},"txt_price":{"text":"<p>The cost of melanoma treatment can range from $6,760 to $13,320:</p><ul><li><a href=\"https://us-uk.bookimed.com/clinics/country=turkey/illness=melanoma/\">Turkey</a>: Immunotherapy with Keytruda (Pembolizumab) from $4,170 to $6,710, Melanoma surgery from $6,000 to $11,170.</li><li><a href=\"https://us-uk.bookimed.com/clinics/country=israel/illness=melanoma/\">Israel</a>: Immunotherapy with Keytruda (Pembolizumab) from $7,500 to $34,650, Mohs microsurgery for $4,700, Wide excision of melanoma for $15,000.</li><li><a href=\"https://us-uk.bookimed.com/clinics/country=republic-of-korea/illness=melanoma/\">South Korea</a>: Immunotherapy with Keytruda (Pembolizumab) from $3,200 to $7,700.</li></ul><p>The doctor will determine the total treatment cost based on your needs and past treatments. You may not need to redo previous tests, which could save money.</p>"},"guide_mc":{"text":"<p>Arrival</p>\n<ul>\n<li>Arrival in the country and regular transfer to your hotel/clinic.</li>\n<li>Reviewing and completing any necessary paperwork.</li>\n<li>Getting settled in your individual chamber.</li>\n</ul>\n\n<p>Diagnostics</p>\n<ul>\n<li>Blood tests to assess your overall health.</li>\n<li>Skin biopsy to confirm melanoma diagnosis.</li>\n<li>Imaging tests for staging and treatment planning.</li>\n</ul>\n\n<p>Treatment Plan Development</p>\n<ul>\n<li>Consultation with oncologist about diagnosis and treatment options.</li>\n<li>Development of an individualized treatment plan.</li>\n</ul>\n\n<p>Treatment</p>\n<ul>\n<li>Surgery under general anesthesia to remove the melanoma.</li>\n<li>Immunotherapy or targeted therapy, if needed.</li>\n<li>Radiation therapy to kill remaining cancer cells, if needed.</li>\n</ul>\n\n<p>Follow-Up</p>\n<ul>\n<li>Regular follow-up appointments to monitor recovery.</li>\n<li>Check-ups includes physical examinations and imaging tests.</li>\n</ul>\n\n<p>Rehabilitation</p>\n<ul>\n<li>Physical therapy if necessary to regain strength and mobility.</li>\n<li>Psychosocial support for emotional well-being.</li>\n</ul>\n\n<p><i>Please note that only a doctor can definitively determine a diagnostic and treatment plan, as each case is individual. In addition to the above-mentioned procedures, other diagnostic methods such as PET-CT, lymphoscintigraphy, sentinel lymph node biopsy, and treatments like chemotherapy may be applied.</i></p>"}}},"articles":[{"id":"en:is-melanoma-curable","name":"Is melanoma curable?","image":{"main":"https://bookimed.s3.eu-central-1.amazonaws.com/_images_without_dir/5bf443eac6793.jpeg"},"author":{"first_name":"Veronika","last_name":"Kazina","avatar":"https://s3.eu-central-1.amazonaws.com/bookimed/_images_without_dir/62fcd8ac5e1e2_b.jpeg"}},{"id":"en:melanoma-treatment-cost","name":"Melanoma Treatment Cost Guide: Prices, Best Clinics, What to 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