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fertilization or no transferable embryo","Ectopic pregnancy","Miscarriage","Small increased risk of congenital anomalies in offspring","Mood changes and bloating from hormones"],"pain":"Mild to moderate: injection discomfort and bloating during stimulation; cramping for 1-2 days after retrieval; transfer is nearly painless.","preparation":["Fertility workup for both partners","Semen analysis and hormone tests (AMH, FSH)","Infectious disease screening","Ovarian stimulation with daily injections for about 8-12 days","Trigger injection 34-36 hours before retrieval","Semen sample or surgical sperm retrieval on retrieval day","Fasting 6-8 hours before sedation"],"recovery_timeline":[{"phase":"Stimulation, days 1-12","description":"Daily hormone injections with 2-4 ultrasound and blood checks.","restrictions":["Avoid strenuous exercise","Avoid alcohol and smoking"]},{"phase":"Egg retrieval, day 12-14","description":"Ultrasound-guided retrieval under sedation, about 20 minutes; eggs are injected with single sperm that day.","restrictions":["No driving for 24 hours","Rest on the day"]},{"phase":"Embryo culture, 3-6 days","description":"Embryos develop in the lab; transfer on day 3 or 5, or freezing of all embryos.","restrictions":["Avoid heavy lifting","Avoid intercourse for a few days"]},{"phase":"Two-week wait","description":"Luteal support; blood hCG test about 10-14 days after transfer.","restrictions":["Avoid strenuous exercise","Avoid baths and swimming"]}],"rehabilitation_days":{"min":1,"max":2,"unit":"days","qualifier":"Recovery from sedation and retrieval cramping."},"result_longevity":"Live birth outcome is permanent; surplus frozen embryos can remain viable for years.","revision_rate_pct":{"min":40,"max":70,"unit":"percent","qualifier":"Patients needing a further ICSI cycle after unsuccessful first cycle, depending on age and embryo quality"},"scars":"No scars; retrieval is through the vaginal wall with a needle.","sessions_or_stages":{"sessions":{"min":1,"max":2,"unit":"visits","qualifier":"One cycle with retrieval and transfer; second visit only if freeze-all with later transfer."},"stages":[{"code":"stimulation","label":"Ovarian stimulation and monitoring","after":{"min":0,"max":12,"unit":"days","qualifier":"From start of injections."}},{"code":"egg_retrieval_icsi","label":"Egg retrieval, sperm injection and fertilization","after":{"min":12,"max":14,"unit":"days","qualifier":"After stimulation start."}},{"code":"embryo_transfer","label":"Embryo transfer","after":{"min":15,"max":19,"unit":"days","qualifier":"Day 3 or day 5 fresh transfer after stimulation start."}}],"qualifier":"Single ICSI cycle; frozen transfer is a separate later step."},"success":{"metric":"Live birth rate per fresh ICSI cycle","value":30,"unit":"percent per started cycle","horizon":"Per cycle, to delivery","population":"Women under 40 with male factor infertility; falls sharply with age","evidence_status":"limited"},"techniques":[{"name":"Standard ICSI with fresh embryo transfer","suits_whom":"Most couples with male factor infertility and good ovarian response.","recovery":"Back to light activity in 1-2 days."},{"name":"ICSI with freeze-all and frozen embryo transfer","suits_whom":"High OHSS risk, genetic testing, or endometrial concerns.","recovery":"Transfer in a later cycle; minimal recovery."},{"name":"ICSI with surgically retrieved sperm (TESA/TESE)","suits_whom":"Men with azoospermia.","recovery":"Scrotal soreness for several days."},{"name":"IMSI or PICSI sperm selection","suits_whom":"Repeated failures or poor embryo quality.","recovery":"Same as standard ICSI."}],"treatment_conditions":["day_case"],"treatment_duration_hours":{"min":0.5,"max":1,"unit":"hours","qualifier":"Egg retrieval about 20-30 minutes; ICSI performed in lab same day."},"initial_assessment_documents":["Semen analysis report","AMH and FSH results","Previous IVF or ICSI cycle reports","Pelvic ultrasound report","Hysterosalpingography or hysteroscopy report (if available)"],"travel_trips":{"min":1,"max":2,"one_trip_possible":true,"qualifier":"Fresh cycle fits one stay of 2-3 weeks; freeze-all needs a second short trip for frozen transfer."},"clinic_checks":{"status":"ok","items":[{"id":"C1","text":"Confirm your infertility is linked to the male partner's sperm, since ICSI lacks scientific support otherwise","scope":"procedure","source":{"url":"https://www.hfea.gov.uk/treatments/explore-all-treatments/intracytoplasmic-sperm-injection-icsi/","host":"hfea.gov.uk","quote":"There is currently no scientific evidence to support the use of ICSI for cases of infertility which is not related to issues with the male partners sperm.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},{"id":"C2","text":"Check whether fertility treatment is regulated in the country and what rules clinics must follow","scope":"treatment_abroad","source":{"url":"https://www.hfea.gov.uk/treatments/explore-all-treatments/fertility-treatment-abroad","host":"hfea.gov.uk","quote":"Is fertility treatment regulated in their country and are there any rules clinics have to follow?","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},{"id":"C3","text":"Check the clinic's record on standards and safety","scope":"treatment_abroad","source":{"url":"https://www.hfea.gov.uk/treatments/explore-all-treatments/fertility-treatment-abroad","host":"hfea.gov.uk","quote":"What is the clinic’s record on standards and safety?","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},{"id":"C4","text":"Check in advance how a complaint would be handled if something goes wrong","scope":"treatment_abroad","source":{"url":"https://www.hfea.gov.uk/treatments/explore-all-treatments/fertility-treatment-abroad","host":"hfea.gov.uk","quote":"You should find out in advance how a complaint will be handled in the event that something goes wrong.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},{"id":"C5","text":"Check the clinic's multiple pregnancy rates","scope":"treatment_abroad","source":{"url":"https://www.hfea.gov.uk/treatments/explore-all-treatments/fertility-treatment-abroad","host":"hfea.gov.uk","quote":"You should also ask about your clinic’s multiple pregnancy rates.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},{"id":"C6","text":"Check how patient records are kept to ensure confidentiality","scope":"treatment_abroad","source":{"url":"https://www.hfea.gov.uk/treatments/explore-all-treatments/fertility-treatment-abroad","host":"hfea.gov.uk","quote":"How are patient records kept to ensure confidentiality?","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},{"id":"C7","text":"Check whether the laboratory follows set procedures","scope":"treatment_type","source":{"url":"https://www.hfea.gov.uk/treatments/explore-all-treatments/fertility-treatment-abroad","host":"hfea.gov.uk","quote":"Does the laboratory have to follow set procedures?","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1},"red_flags":{"status":"ok","items":[{"id":"F1","text":"ICSI is offered for infertility not linked to the male partner's sperm","scope":"procedure","source":{"url":"https://www.hfea.gov.uk/treatments/explore-all-treatments/intracytoplasmic-sperm-injection-icsi/","host":"hfea.gov.uk","quote":"There is currently no scientific evidence to support the use of ICSI for cases of infertility which is not related to issues with the male partners sperm.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},{"id":"F2","text":"A clinic claims very high success rates","scope":"treatment_abroad","source":{"url":"https://www.hfea.gov.uk/treatments/explore-all-treatments/fertility-treatment-abroad","host":"hfea.gov.uk","quote":"Some people prefer to go abroad because they’ve found a clinic which claims to have very high success rates.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},{"id":"F3","text":"The clinic gives no advance account of how complaints would be handled if something goes wrong","scope":"treatment_abroad","source":{"url":"https://www.hfea.gov.uk/treatments/explore-all-treatments/fertility-treatment-abroad","host":"hfea.gov.uk","quote":"You should find out in advance how a complaint will be handled in the event that something goes wrong.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1},"warning_signs":{"status":"ok","items":[{"id":"W1","text":"Abdominal discomfort that causes concern","urgency":"contact_clinic","general":false,"source":{"url":"https://www.newcastle-hospitals.nhs.uk/services/fertility-services/ivf-and-icsi-information-for-patients-having-treatment/risks-of-treatment/","host":"newcastle-hospitals.nhs.uk","quote":"We need to know if you are concerned about abdominal discomfort, start vomiting or are unable to drink anything.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"W2","text":"Vomiting after treatment","urgency":"contact_clinic","general":false,"source":{"url":"https://www.newcastle-hospitals.nhs.uk/services/fertility-services/ivf-and-icsi-information-for-patients-having-treatment/risks-of-treatment/","host":"newcastle-hospitals.nhs.uk","quote":"We need to know if you are concerned about abdominal discomfort, start vomiting or are unable to drink anything.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"W3","text":"Unable to drink anything","urgency":"contact_clinic","general":false,"source":{"url":"https://www.newcastle-hospitals.nhs.uk/services/fertility-services/ivf-and-icsi-information-for-patients-having-treatment/risks-of-treatment/","host":"newcastle-hospitals.nhs.uk","quote":"We need to know if you are concerned about abdominal discomfort, start vomiting or are unable to drink anything.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"take_home":{"status":"ok","items":[{"id":"T1","text":"Home doctor needs the clinic's follow-up recommendations in a written discharge summary","document":"discharge summary","source":{"url":"https://sbuhb.nhs.wales/about-us/individual-patient-commissioning/ipc-folder/advice-on-accessing-treatment-abroad","host":"sbuhb.nhs.wales","quote":"When you have treatment abroad, you must ask the treatment provider for their follow-up recommendations documented within a written discharge summary in English.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T2","text":"Home doctor needs the dates for required blood tests and follow-up appointments","document":"written aftercare plan","source":{"url":"https://sbuhb.nhs.wales/about-us/individual-patient-commissioning/ipc-folder/advice-on-accessing-treatment-abroad","host":"sbuhb.nhs.wales","quote":"This should include any medication and doses, as well as any dates that blood tests and follow-up appointments must be carried out.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1},"alternatives":{"status":"ok","items":[{"id":"A1","text":"Your sperm numbers and quality are not a significant concern","name":"Standard IVF","source":{"url":"https://mft.nhs.uk/saint-marys/services/gynaecology/reproductive-medicine/in-vitro-fertilisation-ivf/","host":"mft.nhs.uk","quote":"This is advised where there is no significant concern about sperm numbers or quality.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200},"operation_id":null}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1},"technique_details":{"status":"ok","items":[{"id":"standard-icsi","name":"Standard ICSI with fresh embryo transfer","how_it_works":{"text":"Individual sperm are selected and injected into individual mature eggs","source":{"url":"https://mft.nhs.uk/saint-marys/services/gynaecology/reproductive-medicine/in-vitro-fertilisation-ivf/","host":"mft.nhs.uk","quote":"In this technique, individual sperm are selected and injected into individual mature eggs by the scientist.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},"recovery_daily":{"event":"back_to_daily_activities","min":0,"max":0,"unit":"days","label":"Same day","source":{"url":"https://my.clevelandclinic.org/health/treatments/22457-ivf","host":"my.clevelandclinic.org","quote":"Many people will return to normal activities right after their egg retrieval procedure.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}}},{"id":"icsi-freeze-all","name":"ICSI with freeze-all and frozen embryo transfer","how_it_works":{"status":"missing","reason":"no_official_source"},"recovery_daily":{"status":"missing","reason":"no_official_source"}},{"id":"icsi-surgically-retrieved","name":"ICSI with surgically retrieved sperm (TESA/TESE)","how_it_works":{"text":"Sperm is extracted surgically when none is found in semen","source":{"url":"https://www.homerton.nhs.uk/fertility-treatments-and-services","host":"homerton.nhs.uk","quote":"If no sperm is found in the male partner’s semen sample, it is sometimes possible to extract sperm surgically.","tier":"tier1_medical","fetched_at":"2026-11-14","http_status":200}},"recovery_daily":{"status":"missing","reason":"no_official_source"}},{"id":"imsi","name":"IMSI or PICSI sperm selection","how_it_works":{"status":"missing","reason":"no_official_source"},"recovery_daily":{"status":"missing","reason":"no_official_source"}}],"checked_at":"2026-11-14","next_check_at":"2027-11-14","version":1}}},"hrefLanguages":[{"rel":"alternate","hreflang":"ru","language":"ru","href":"https://ru.bookimed.com/clinics/country=cyprus/city=cyprus/procedure=iksi-intracitoplazmaticheskaya-inekciya-spermatozoida/"}],"offerFilters":{"offer_count":0,"price_filter":{"from":0,"to":0,"avg":0}},"offersBlock":{},"illnessesByOperation":[{"id":52,"alias":"infertility","name":"Infertility"}],"rendersOffersList":false,"fewClinics":true,"topCountriesCount":0}