![\"leukemia](\"https://s3.eu-central-1.amazonaws.com/bookimed/_images_without_dir/66e199309418d.jpeg\")
Prof. Freddy Aviv heads the Hemato-Oncology Institute at Israel's largest JCI-accredited center, bringing _doctor_176_years_ of leukemia expertise. Diagnostics may start around $310 for complete lab tests, with PET-CT around $1,620. A comprehensive bone marrow aspiration and biopsy with pathology typically runs $2,890. The center offers an EBMT-certified transplant program and uses the Novalis Truebeam STx for precise radiotherapy.
Sourasky Medical Center (Ichilov) is the largest multidisciplinary hospital in Israel and a JCI-accredited facility. It has been named a top medical tourism destination by Newsweek. Its core strengths are oncology, onco-hematology, neurosurgery, and rehabilitation.
Leading leukemia specialist at Sourasky Medical Center (Ichilov) – Israel's largest and most advanced hospital.
The doctor is a highly experienced Obstetrician and Gynaecologist with over 25 years in the field. Specializing in Obstetrics & Gynaecology Reproduction Medicine, the doctor is proficient in treatments such as Intrauterine Insemination (IUI), Ovulation Induction Procedure, Ovarian Drilling, and Urethral Valves management.
The doctor has completed a fellowship at the Ronald O Perelman and Claudia Cohen Centre, holds a diploma from Ireland, and earned an MBBS from the University of Mysore, India.
","specialities":[{"id":"hmt.001","name":"Hematologist","illness_kind_id":20},{"id":"onc.001","name":"Clinical oncologist","illness_kind_id":10}],"statistics":{"review_count":0,"review_score":0,"operations_performed_count":0,"awards_count":0}},"clinic":{"id":1,"alias":"sourasky-medical-center","name":"Sourasky Medical Center (Ichilov)","logo":"https://s3.eu-central-1.amazonaws.com/bookimed/clinic_logo/1-6ac3c0e614474.png","short_description":"Sourasky Medical Center (Ichilov) is the largest multidisciplinary hospital in Israel and a JCI-accredited facility. It has been named a top medical tourism destination by Newsweek. Its core strengths are oncology, onco-hematology, neurosurgery, and rehabilitation.
Dr. Ram has performed several hundred stem cell transplants, a cornerstone treatment for leukemia, at Sourasky Medical Center.
Dr. Ron Ram is a board-certified hematologist-oncologist at Sourasky Medical Center. He has performed several hundred stem cell transplants for blood cancer patients. Dr. Ram holds certifications in Internal Medicine, Hematology, and Medical Oncology. He completed his medical training and fellowship at prestigious New York institutions.
Sourasky Medical Center (Ichilov) is the largest multidisciplinary hospital in Israel and a JCI-accredited facility. It has been named a top medical tourism destination by Newsweek. Its core strengths are oncology, onco-hematology, neurosurgery, and rehabilitation.
Head of Pediatric Oncohematology at Dana Dwek Children's Hospital – Dr. El Hasid specializes in bone marrow and umbilical blood transplants for children.
Dr. Ronit El Hasid leads the Department of Pediatric Oncohematology at Dana Dwek Children's Hospital. She is a specialist in bone marrow and umbilical blood transplantation for children. She has performed over 300 successful transplantations throughout her career. Dr. El Hasid previously practiced at the City of Hope Hospital in Los Angeles.
Sourasky Medical Center (Ichilov) is the largest multidisciplinary hospital in Israel and a JCI-accredited facility. It has been named a top medical tourism destination by Newsweek. Its core strengths are oncology, onco-hematology, neurosurgery, and rehabilitation.
Dr. Shapira is a senior bone marrow transplantation specialist at the prestigious Sourasky Medical Center in Tel Aviv.
The doctor is an experienced specialist in Bone Marrow Transplantation, having graduated from the Hebrew University Medical School in 1999. Following this, the doctor specialized in internal medicine at Hadassah Medical Center. The doctor later joined the Bone Marrow Transplantation department at Hadassah as a senior physician, contributing significant expertise to the field.
","specialities":[{"id":"hmt.001","name":"Hematologist","illness_kind_id":20},{"id":"onc.007","name":"Hematologist/oncologist","illness_kind_id":20}],"statistics":{"review_count":1,"review_score":5,"operations_performed_count":0,"awards_count":0}},"clinic":{"id":1,"alias":"sourasky-medical-center","name":"Sourasky Medical Center (Ichilov)","logo":"https://s3.eu-central-1.amazonaws.com/bookimed/clinic_logo/1-6ac3c0e614474.png","short_description":"Sourasky Medical Center (Ichilov) is the largest multidisciplinary hospital in Israel and a JCI-accredited facility. It has been named a top medical tourism destination by Newsweek. Its core strengths are oncology, onco-hematology, neurosurgery, and rehabilitation.
Head of Hemato-Oncology Institute at Ichilov Medical Center – Professor Aviv specializes in leukemias and expert bone marrow transplantation.
The doctor is an experienced oncohematologist with 31 years of practice at Sourasky Medical Center. Specializing in the treatment of blood cancers, the doctor has contributed significantly to advancements in oncohematology. With a focus on patient-centered care, the doctor has been involved in numerous clinical trials and research projects aimed at improving therapeutic outcomes. The doctor is recognized for their expertise in diagnosing and managing complex hematological conditions, providing comprehensive care to patients.
","specialities":[{"id":"hmt.001","name":"Hematologist","illness_kind_id":20},{"id":"onc.007","name":"Hematologist/oncologist","illness_kind_id":20}],"statistics":{"review_count":0,"review_score":0,"operations_performed_count":0,"awards_count":0}},"clinic":{"id":1,"alias":"sourasky-medical-center","name":"Sourasky Medical Center (Ichilov)","logo":"https://s3.eu-central-1.amazonaws.com/bookimed/clinic_logo/1-6ac3c0e614474.png","short_description":"Sourasky Medical Center (Ichilov) is the largest multidisciplinary hospital in Israel and a JCI-accredited facility. It has been named a top medical tourism destination by Newsweek. Its core strengths are oncology, onco-hematology, neurosurgery, and rehabilitation.
Leads the pediatric hematology oncology department at Sourasky Medical Center, a major center for treating childhood leukemia in Israel.
Dr. Dror Levin directs the Pediatric Hematology Oncology Department at Sourasky Medical Center. He is a leading expert in treating childhood blood disorders and bone sarcomas. Dr. Levin trained at the Rizzoli Orthopaedic Institute in Italy. This center is a global leader in bone and soft tissue oncology.
Sourasky Medical Center (Ichilov) is the largest multidisciplinary hospital in Israel and a JCI-accredited facility. It has been named a top medical tourism destination by Newsweek. Its core strengths are oncology, onco-hematology, neurosurgery, and rehabilitation.
Dr. Herishanu's research and treatment focus is on chronic lymphocytic leukemia, the most common adult leukemia. He has received over ten national and international awards for his work in this field.
Dr. Herishanu Yair is a hematologist-oncologist at Sourasky Medical Center in Tel Aviv. He is a recognized expert in chronic lymphocytic leukemia research and treatment. Dr. Yair received the Young Investigator Research Prize for his clinical contributions. He works at a hospital ranked among the world's top 10 for medical tourism.
Sourasky Medical Center (Ichilov) is the largest multidisciplinary hospital in Israel and a JCI-accredited facility. It has been named a top medical tourism destination by Newsweek. Its core strengths are oncology, onco-hematology, neurosurgery, and rehabilitation.
Dr. Spielberg is an oncohematologist specializing in blood cancers at Assuta Medical Center.
The doctor is an experienced oncohematologist specializing in the treatment of blood cancers and related disorders. With a focus on innovative therapies and personalized patient care, the doctor has contributed significantly to advancements in the field. The doctor is affiliated with several leading medical institutions and has published numerous research papers in peer-reviewed journals.
The doctor is also actively involved in clinical trials aiming to improve outcomes for patients with hematological malignancies. Board-certified in hematology and oncology, the doctor is recognized for expertise in both clinical practice and research.
","statistics":{"review_count":0,"review_score":0,"operations_performed_count":0,"awards_count":0}},"clinic":{"id":8,"alias":"assuta-hospital","name":"Assuta Medical Center","short_description":"Assuta Medical Center is the largest private medical complex in Israel, with 11 hospitals and 1,500 doctors. Its main specialties are oncology, surgery, cardiology, neurosurgery, gynecology, and IVF treatment. JCI-accredited since 2011, it was the first Israeli hospital to earn this recognition.
Leukemia is a cancer that starts in the bone marrow, where blood cells are produced. It occurs when abnormal white blood cells form and multiply uncontrollably.
\n\nPatients may face additional costs beyond conventional medical bills, such as:
\n\nCaregiver loss of earnings;
\n\tTraveling for treatment;
\n\tOut-of-pocket expenses related to medications and insurance premiums.
\n\tThe 5-year survival rate for all types of leukemia is 67%.
\n\n
(Comparison of normal blood cells vs. leukemia. Source - BD Biosciences)
\n\nThe National Cancer Institute (NCI) recognizes leukemia as a type of cancer that requires specialized treatment and care. The treatment strategy is complex and depends on multiple factors. Yet, it’s possible to ease the disease progress with a personalized treatment plan.
\n\nLeukemia begins when a genetic mutation occurs in the DNA of bone marrow cells. These mutations cause the cells to grow and divide rapidly, forming abnormal white blood cells. These abnormal cells crowd out the healthy blood cells, leading to the symptoms of leukemia.
\n\nThe risk factors that can increase the likelihood of developing leukemia are:
\n\n🧬 Genetic factors, such as inherited conditions or family history of leukemia.
\n\n☢️ Exposure to radiation or certain chemicals, such as benzene.
\n\n🚬 Smoking, which increases the risk of some types of leukemia.
\n\n💉 Previous cancer treatments, including chemotherapy or radiation therapy.
\n\nLeukemia is classified into four main types based on the speed of progression and the type of blood cells affected:
\n\nAcute Lymphoblastic Leukemia (ALL) progresses rapidly and affects immature lymphocytes, a type of white blood cell.
\n\tAcute Myeloid Leukemia (AML) affects myeloid cells, which form white blood cells, red blood cells, and platelets.
\n\tChronic Lymphocytic Leukemia (CLL). A slower-growing leukemia affects mature lymphocytes.
\n\tChronic Myeloid Leukemia (CML) develops slowly and affects mature myeloid cells.
\n\tMultiple myeloma, another type of blood cancer, also has significant financial implications, often involving high costs for various stages of care.
\n\nThe doctors classify leukemia by:
\n\nHow advanced the disease is;
\n\tHow many abnormal cells are in the blood;
\n\tWhether the cancer has metastasized.
\n\t| Type of Leukemia | \n\t\t\tAge when diagnosed | \n\t\t\tProjected new cases in the next year | \n\t\t
| ALL | \n\t\t\t2-5 y.o. | \n\t\t\t6,550 | \n\t\t
| AML | \n\t\t\t65 years and older | \n\t\t\t20,800 | \n\t\t
| CLL | \n\t\t\t60-70 y.o. | \n\t\t\t20,700 | \n\t\t
| CML | \n\t\t\t~64 y.o. | \n\t\t\t9,280 | \n\t\t
Leukemia can present with a variety of symptoms, which may include:
\n\nFatigue and weakness;
\n\tFrequent infections due to a weakened immune system;
\n\tEasy bruising or bleeding, such as frequent nosebleeds or bleeding gums;
\n\tPetechiae (flat, pinpoint spots under the skin caused by bleeding);
\n\tPainless swellings in the neck, armpit, belly, or groin;
\n\tBone or joint pain;
\n\tShortness of breath;
\n\tFrequent infections;
\n\tThe feeling of fullness below the ribs;
\n\tUnexplained weight loss;
\n\tFever or night sweats.
\n\t![\"best](\"https://s3.eu-central-1.amazonaws.com/bookimed/_images_without_dir/66e198fa33c83.jpeg\")
As these symptoms often sound like flu or other common disease, the doctors perform lab and instrumental tests to detect the presence of cancer.
\n\nAlong with asking about personal and family health history and doing a physical exam, the doctor may do some tests, including:
\n\nComplete blood count (CBC) to check for abnormal white cells or low red blood cell counts;
\n\tIn a blood chemistry study, doctors check the levels of different substances in blood, such as glucose, fats, and proteins);
\n\tFor a peripheral blood smear, doctors examine a blood sample under a microscope to see if there are any abnormal cells. They look at the types and numbers of white blood cells, platelets, and changes in the shape of the blood cells;
\n\tImaging tests, like CT scans or MRIs, to check for bone metastasis;
\n\tDuring a bone marrow aspiration and biopsy, the doctor removes a small sample of bone marrow, blood, and bone from the hip or chest bone using a needle. A pathologist examines the sample under a microscope to spot any abnormal cells.
\n\t![\"leukemia](\"https://s3.eu-central-1.amazonaws.com/bookimed/_images_without_dir/66e19928df2de.jpeg\")
(Bone Marrow Aspiration and Biopsy, Source - National Cancer Institute)
\n\nCytogenetic testing determines whether there are missing or broken chromosomes and abnormal genes in a cell’s genome. Usually, doctors apply it to detect CML or Philadelphia-positive acute lymphoblastic leukemia (Ph+ALL).
\n\nThe most commonly used is the BCR-ABL1 method, which looks for a pathological gene called BCR-ABL1. It is an acquired genetic change, meaning patients do not take it from their parents and cannot pass it on to their children.
\n\nThe treatment of childhood acute lymphoblastic leukemia (ALL) happens in three main stages:
\n\nRemission induction. This is the first stage, where the aim is to destroy leukemia cells in the blood so the leukemia becomes remission (meaning there are no signs of cancer).
\n\tConsolidation/intensification. Once the leukemia is in remission, the goal is to get rid of any remaining cancer cells to prevent recurrence.
\n\tMaintenance. In this final stage, the goal is to kill any leftover leukemia cells. The treatment doses are usually lower during this phase compared to the earlier stages. This is also called the continuation phase.
\n\t![\"leukemia](\"https://s3.eu-central-1.amazonaws.com/bookimed/_images_without_dir/66e199212b4dc.jpeg\")
The leukemia treatment centers offer different approaches for children with ALL. In addition to standard medical treatments, patients may face financial burdens from other therapies, such as travel, lodging, and alternative treatments.
\n\n| Risk Level | \n\t\t\tMain Procedure | \n\t\t
| Standard risk | \n\t\t\t-Intrathecal chemotherapy: \n\t\t\t-Stem cell transplant during the first remission. | \n\t\t
| High risk | \n\t\t\t-Intrathecal and systemic chemotherapy \n\t\t\t-Radiation therapy. | \n\t\t
| Very high risk | \n\t\t\t-Intrathecal and systemic chemotherapy \n\t\t\t-Radiation therapy; \n\t\t\t-Stem cell transplant not during the first remission. | \n\t\t
When it comes to cancer treatment, there is no one-size-fits-all approach. The best leukemia treatment centers in the world offer various options tailored to the type and stage of cancer, as well as the patient’s overall health.
\n\nClinical trials play a pivotal role in advancing cancer treatment. These trials provide patients access to new and innovative therapies that are not yet widely available. Participating in a clinical trial can be valuable for those who have not responded to standard treatments or are seeking alternative options.
\n\nStandard treatment methods include:
\n\n✔️Surgery;
\n\t✔️Chemotherapy;
\n\t✔️Radiation therapy;
\n\tStem cell transplantation, for instance, is a cutting-edge treatment that has shown promise in treating blood cancer. This procedure involves replacing damaged or destroyed bone marrow with healthy stem cells, which can help restore average blood cell production.
\n\nStem cell transplants rarely serve as the first treatment for children and teens with ALL. Doctors typically use them if the leukemia returns after initial treatment.
\n\nIn a stem cell transplant, doctors collect stem cells from a donor’s blood or bone marrow, freeze them for later use, and store them. After the patient finishes chemotherapy and radiation, doctors infuse the stem cells into the patient’s body. Transplants for leukemia patients grow into red and white particles, restoring the regular bloodstream.
\n\nBookimed has ranked the best hospitals for treating blood cancers. Based on our Smart Ranking System, the top facilities are in Spain, Israel, and Turkey.
\n\nThe top leukemia treatment centers are:
\n\nSJD Barcelona Children’s Hospital (Spain). The hospital belongs to the ITCC (Innovative Therapies for Children with Cancer) consortium. It is the only hospital in Spain and among several in Europe treating lymphoblastic leukemia insensitive to traditional therapy with innovative CART-T therapy.
\n\tSourasky Medical Center (Ichilov) (Israel). According to Newsweek magazine, the hospital is one of the best in Europe for treating blood cancer. The oncologists have over 20 years of experience, with
\n\tAnadolu Medical Center (Turkey). The hospital has ESMO (European Society for Medical Oncology) certification, which proves its compliance with strict blood cancer treatment standards. Anadolu Medical Center also partners with Johns Hopkins Hospital in the USA, using the latest equipment for precise diagnosis and treatment.
\n\tThe type and treatment cost depends on leukemia's stage and severity. Here's a short overview of the most-demanded blood cancer destinations and their treatment costs.
\n\n| Country | \n\t\t\tTurkey | \n\t\t\tSpain | \n\t\t\tIsrael | \n\t\t
| CAR-T cell therapy cost | \n\t\t\tFrom $60,000 to $95,500 | \n\t\t\tFrom $133,607 | \n\t\t\tFrom $90,000 to $120,000 | \n\t\t
| Chemotherapy cost | \n\t\t\tFrom $5,200 to $13,480 | \n\t\t\tFrom $15,200 to $28,200 | \n\t\t\tFrom $6525 | \n\t\t
Health insurance plans help cover expensive drugs and procedures. Many people have insurance through their jobs or by purchasing a plan themselves. However, some treatments or costs may not be fully covered.
\n\n![\"leukemia](\"https://s3.eu-central-1.amazonaws.com/bookimed/_images_without_dir/66e1991a0661d.jpeg\")
The are several types of plans:
\n\nHealth Maintenance Organizations (HMOs). Lower costs with a specific network of doctors and hospitals. A primary care doctor (PCP) is chosen, and specialists need referrals.
\n\tPreferred Provider Organizations (PPOs). More flexibility in choosing doctors, both in-network and out-of-network, but out-of-network care costs more. No referrals are needed for specialists.
\n\tPoint-of-Service (POS). This health insurance plan is a mix of HMO and PPO. Members choose between in-network or out-of-network providers but usually need a referral to see a specialist.
\n\tFee-for-Service (FFS). Most flexible but with higher costs. Members pay upfront for care, submit claims for reimbursement, and often handle more paperwork.
\n\tThe patients who struggle to find healthcare professionals can fill a request on Bookimed, and the medical coordinator will contact an individual treatment plan.
\n\nSeeking a lower cost of childhood leukemia treatment should not be the sole factor influencing the hospital choice. Here's what else is essential:
\n\nHospital's Accreditation. The more evaluations the center has from international organizations, the higher its success rate will be. The most popular communities are National Cancer Institute and Joint Commission International. They provide the ranking of accredited centers with proven treatment and diagnostic standards.
\n\tLevel of Doctor's Expertise. Leukemia is a multimodal disease requiring the same approach. It demands high qualification in terms of modern treatment tools. Plus, patients can check the doctor's experience by looking at the number of successful procedures (or surgeries) they performed so far.
\n\tPatients Safety. For example, if the hospital has HEPA-filtered wards, ensuring 100% sterilization. HEPA filters usually contain glass or plastic fibers. It doesn't allow airborne pathogens into the environment and works excellently with UV light air filtration systems.
\n\tFor patients with less time to choose a center, Bookimed can find the best treatment facility and develop an individual treatment plan. Just submit a free request on our website to contact the medical coordinator and find a solution to your problem.
\n\nThe average price range for chemotherapy is $1,000-$5,000. This depends on a disease's complexity and medication response. According to recent data, about 2 out of 3 people with AML who get standard induction chemotherapy (chemo) go into remission.
\n\nThe average cost for leukemia treatment is:
\n\nVincristine, used for ALL, costs around $25 for a supply of 2 milliliters;
\n\tMitoxantrone, used for AML, is about $186 for a supply of 10 milliliters;
\n\tImbruvica (enzyme inhibitor), used for CLL, will cost around $616 per tablet.
\n\tIn 2024, the FDA approved blinatumomab for adult and pediatric patients one month and older with a specific type of B-cell precursor ALL. This treatment is applicable when cancer signs disappear after initial therapy.
\n\nChildhood Acute Lymphoblastic Leukemia. Comprehensive Cancer Information - NCI. URL: https://www.cancer.gov/types/leukemia/patient/child-all-treatment-pdq#_62 (date of access: 10.09.2024).
\n\nKey Statistics for Acute Lymphocytic Leukemia (ALL). Information and Resources about Cancer: Breast, Colon, Lung, Prostate, Skin | American Cancer Society. URL: https://www.cancer.org/cancer/types/acute-lymphocytic-leukemia/about/key-statistics.html (date of access: 10.09.2024).
\n\nLeukemia & Lymphoma Society | Blood Cancer Leaders | LLS. URL: https://www.lls.org/managing-your-cancer/finances-and-insurance-coverage/insurance-coverage (date of access: 11.09.2024).
\n\nSurvival Rate of Leukemia: Stats by Type, Age, and More. Healthline. URL: https://www.healthline.com/health/leukemia/survival-rate-of-leukemia (date of access: 10.09.2024).
\n\nTreatment Response Rates for Acute Myeloid Leukemia (AML). Information and Resources about Cancer: Breast, Colon, Lung, Prostate, Skin | American Cancer Society. URL: https://www.cancer.org/cancer/types/acute-myeloid-leukemia/treating/response-rates.html (date of access: 10.09.2024).
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The cost of leukemia treatment can range from $14,380 to $23,070:
The doctor will determine the total treatment cost based on your needs and past treatments.
"},"guide_mc":{"text":"Arrival
\nDiagnostics
\nTreatment plan development
\nTreatment
\nFollow-up
\nRehabilitation
\nPlease note, only a doctor can determine the most appropriate diagnostic and treatment plan for you, and it\"s individual. Additional diagnostic and treatment options could include genetic testing, immunotherapy, or clinical trials.
"}}},"articles":[{"id":"en:how-much-leukemia-treatment-costs","name":"How Much Does Leukemia Treatment Cost? 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