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Immunotherapy Regenerative Medicine specializes in advanced bone grafting techniques with a focus on regenerative medicine. Dr. Ernesto Romero, a pioneer in stem cell and immunotherapy technology with _doctor_5860_years_ of experience, leads the team. He holds a Master’s Degree in Regenerative Medicine and has collaborated on clinical protocols involving mesenchymal stem cells for various degenerative conditions.

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Immunotherapy Regenerative Medicine is in Puerto Vallarta with over 20 years in regenerative medicine. It specializes in stem cell therapy, immunology, and anti-aging. The clinic holds CSG accreditation.

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Holistic Bio Spa® offers specialized Bone Graft procedures as part of its regenerative medicine services. Dr. Eduardo Fernandez, a certified stem cell therapy expert and member of the Mexican College of Stem Cells and Regenerative Medicine, brings advanced expertise to the team. The clinic provides a holistic approach to bone regeneration, integrating alternative therapies with evidence-based treatments.

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Dr. Ernesto Romero is a regenerative medicine specialist at Immunotherapy Regenerative Medicine in Mexico. He founded the Bioplenum biotechnological institute. Dr. Romero has researched stem cell protocols for autoimmune and degenerative diseases. He holds a Master’s degree in Regenerative Medicine from Universidad Catolica de Murcia.

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Dr. Eduardo Fernandez is one of only 50 certified stem cell experts in Mexico. He practices at Holistic Bio Spa in Puerto Vallarta. He specializes in regenerative medicine and wellness therapies. Dr. Fernandez treat conditions like Alzheimer’s, Parkinson's, and chronic pain. He passed a rigorous eight-hour examination for his national certification.

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Bone tissue transplant to repair and rebuild diseased or damaged bones.

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Bone transplant to enhance healing, stability, and support where bone loss occurred or in fractures.

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The procedure involves using small pieces of bone to help regenerate damaged areas, promoting faster and more effective healing.

"},"1189":{"operation":{"name":"Synthetic bone graft","alias":"synthetic-bone-graft","use_for_listing":true},"country_price":{"US":{"amount":600,"max_amount":1400,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"TR":{"amount":220,"max_amount":480,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"MX":{"amount":350,"max_amount":800,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"TH":{"amount":200,"max_amount":550,"currency":"USD","clinic_count":1,"price_kind":"from_range","price_source":"tariff","scope":"country"}},"available_clinics":{"US":false,"TR":false,"MX":false,"TH":true},"description":"

This therapy recreates damaged bone using lab-grown substitutes, aiding natural bone growth and quick, efficient healing.

"},"1242":{"operation":{"name":"Ridge augmentation","alias":"ridge-augmentation","use_for_listing":true},"country_price":{"US":{"amount":1400,"max_amount":3200,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"TR":{"amount":1100,"max_amount":0,"currency":"USD","clinic_count":1,"price_kind":"from","price_source":"tariff","scope":"country"},"MX":{"amount":800,"max_amount":1300,"currency":"USD","clinic_count":1,"price_kind":"from_range","price_source":"tariff","scope":"country"},"TH":{"amount":500,"max_amount":1300,"currency":"USD","clinic_count":1,"price_kind":"from_range","price_source":"tariff","scope":"country"}},"available_clinics":{"US":false,"TR":true,"MX":true,"TH":true},"description":"

The procedure rebuilds jawbone contours, aiding dental structures and enhancing oral aesthetics with minimal complications.

"},"1243":{"operation":{"name":"Socket preservation","alias":"socket-preservation","use_for_listing":true},"country_price":{"US":{"amount":450,"max_amount":1100,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"TR":{"amount":110,"max_amount":480,"currency":"USD","clinic_count":1,"price_kind":"from_range","price_source":"tariff","scope":"country"},"MX":{"amount":250,"max_amount":750,"currency":"USD","clinic_count":3,"price_kind":"from_range","price_source":"tariff","scope":"country"},"TH":{"amount":250,"max_amount":850,"currency":"USD","clinic_count":1,"price_kind":"from_range","price_source":"tariff","scope":"country"}},"available_clinics":{"US":false,"TR":true,"MX":true,"TH":true},"description":"

This therapy preserves the tooth\"s socket after extraction, maintaining bone volume for future implants, enhancing healing.

"},"1301":{"operation":{"name":"Dental bone regeneration","alias":"dental-bone-regeneration","use_for_listing":true},"country_price":{"US":{"amount":800,"max_amount":2600,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"TR":{"amount":1100,"max_amount":0,"currency":"USD","clinic_count":1,"price_kind":"from","price_source":"tariff","scope":"country"},"MX":{"amount":600,"max_amount":1100,"currency":"USD","clinic_count":1,"price_kind":"from_range","price_source":"tariff","scope":"country"},"TH":{"amount":600,"max_amount":1100,"currency":"USD","clinic_count":2,"price_kind":"from_range","price_source":"tariff","scope":"country"}},"available_clinics":{"US":false,"TR":true,"MX":true,"TH":true},"description":"

This procedure restores lost bone tissue, reinforcing jaw stability to place dental implants using advanced medical technology.

"},"1311":{"operation":{"name":"Collagen Membrane","alias":"collagen-membrane","use_for_listing":true},"country_price":{"US":{"amount":450,"max_amount":900,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"TR":{"amount":120,"max_amount":230,"currency":"USD","clinic_count":5,"price_kind":"from_range","price_source":"tariff","scope":"country"},"MX":{"amount":200,"max_amount":550,"currency":"USD","clinic_count":3,"price_kind":"from_range","price_source":"tariff","scope":"country"},"TH":{"amount":190,"max_amount":450,"currency":"USD","clinic_count":2,"price_kind":"from_range","price_source":"tariff","scope":"country"}},"available_clinics":{"US":false,"TR":true,"MX":true,"TH":true},"description":"

This therapy uses a natural, biocompatible barrier for dental bone grafts, promoting strong, healthy tissue growth.

"}}},"operationIndicators":{"details":{"anesthesia":"general","days_in_clinic":2,"days_in_country":7,"rehabilitation_days":4,"satisfied_percent":78,"treatment_duration_hours":3},"illness_kind_details":{"requests_processed":0}},"direction":{"id":31,"name":"Dental Treatment","alias":"dentistry"},"illness_kind":{"id":31,"name":{"en":"Dental Treatment"}},"parsed_details":{"procedure_type":"surgery","fields":{"anesthesia":["local","local_sedation","general"],"back_to_work_days":{"min":2,"max":7,"unit":"days","qualifier":"Dental ridge graft; desk work sooner, physical work later; swelling and extent of grafting move it."},"complication_rate_pct":{"min":5,"max":20,"unit":"percent","qualifier":"Any complication within 3 months, mostly minor swelling, membrane exposure or infection; serious ones under 3%."},"contraindications":["Active infection at the graft or donor site","Uncontrolled diabetes or other conditions that markedly impair healing","Active smoking or nicotine use (relative; 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size."},"fly_home_after_days":{"min":7,"max":10,"unit":"days","qualifier":"After first wound check; depends on swelling, sinus involvement and surgeon clearance."},"follow_up_visits":[{"purpose":"wound_check","after":{"min":5,"max":7,"unit":"days","qualifier":"Early check of wound and swelling before flight home."},"requirement":"routine"},{"purpose":"suture_removal","after":{"min":7,"max":10,"unit":"days","qualifier":"Removal of non-resorbable sutures if used, before flight home."},"requirement":"conditional"},{"purpose":"assessment","after":{"min":90,"max":120,"unit":"days","qualifier":"Imaging to assess graft integration."},"requirement":"routine"},{"purpose":"result_review","after":{"min":120,"max":270,"unit":"days","qualifier":"CBCT review before implant placement."},"requirement":"routine"}],"indications":["Bone defects or loss from trauma, tumor resection or infection","Fracture nonunion or delayed union","Alveolar ridge deficiency before dental implant placement","Periodontal bone defects or sinus floor augmentation","Spinal fusion","Joint reconstruction or arthrodesis requiring bone stock"],"main_risks":["Infection","Graft resorption, failure or non-integration","Bleeding or hematoma","Donor-site pain, numbness or morbidity when autograft is used","Nerve or adjacent structure injury","Wound dehiscence or delayed healing","Need for repeat surgery","Anesthesia-related risks"],"pain":"Usually moderate in the first days after surgery and controlled with standard analgesics; autograft donor sites such as the iliac crest can be more painful and for longer than the recipient site.","preparation":["Exam and imaging (X-ray, CT or CBCT) for graft planning","Medical history and fitness review","Stop smoking before and after surgery","Fasting if general or sedation anesthesia is planned","Discuss graft material choice (autograft, allograft, xenograft or synthetic)","Arrange transport home and aftercare"],"recovery_timeline":[{"phase":"Days 1-3","description":"Swelling, mild bruising and moderate pain controlled with standard analgesics.","restrictions":["Soft cold diet","No brushing at graft site","No smoking"]},{"phase":"Days 4-14","description":"Swelling subsides and gum begins to heal; sutures are removed or resorb.","restrictions":["Avoid pressure on graft","No strenuous exercise","Use prescribed mouth rinse"]},{"phase":"Weeks 3-6","description":"Soft tissue heals and normal diet gradually resumes.","restrictions":["Avoid chewing on graft area","Avoid temporary denture pressure"]},{"phase":"Months 4-9","description":"Graft integrates into living bone, then implant placement can be planned.","restrictions":["No smoking","Maintain oral hygiene"]}],"rehabilitation_days":{"min":21,"max":42,"unit":"days","qualifier":"Return to normal diet and activities; gradual over weeks; depends on graft extent and swelling."},"result_longevity":"Once integrated, the graft usually becomes living bone and can last long-term, but longevity depends on site, graft material, healing and later loading or oral hygiene.","revision_rate_pct":{"min":3,"max":10,"unit":"percent","qualifier":"Repeat grafting after graft failure or inadequate bone volume, usually within 12 months."},"scars":"Intraoral incisions leave no visible scar; sutures close the gum.","sessions_or_stages":{"sessions":{"min":1,"max":1,"unit":"visits","qualifier":"One grafting surgery for a single site."},"stages":[{"code":"graft_surgery","label":"Bone graft surgery","after":{"min":0,"max":0,"unit":"days","qualifier":"Day of procedure."}},{"code":"integration_review","label":"Imaging review of graft integration","after":{"min":120,"max":270,"unit":"days","qualifier":"Depends on graft material and defect size."}}],"qualifier":"Single grafting surgery, followed by a healing period before implant placement."},"success":{"metric":"Graft integration allowing successful implant placement","value":90,"unit":"percent","horizon":"4-9 months after grafting","population":"Adults with dental ridge deficiency grafted before implant placement","evidence_status":"limited"},"techniques":[{"name":"Autograft (patient's own bone)","suits_whom":"Larger or critical defects, or nonunions, where the best biological healing is needed.","recovery":"Adds donor-site recovery and pain."},{"name":"Allograft (donor bone)","suits_whom":"Patients wanting to avoid a donor site, or moderate defects and ridge or sinus augmentation.","recovery":"No donor site, with graft incorporation over months."},{"name":"Xenograft or synthetic substitute","suits_whom":"Smaller contained defects, often in dental and periodontal use.","recovery":"Mostly slow graft integration, often with no donor-site pain."}],"treatment_conditions":["outpatient"],"treatment_duration_hours":{"min":1,"max":2,"unit":"hours","qualifier":"Single-site dental graft; sinus lift or larger defect takes longer."},"initial_assessment_documents":["X-ray of the affected area","CT scan of the defect or graft site","MRI report (if available)","Previous surgery or implant reports","Panoramic dental X-ray (OPG) for dental grafts","List of blood thinners and bone-affecting drugs"],"travel_trips":{"min":1,"max":2,"one_trip_possible":true,"qualifier":"Single-site dental graft: one trip; second only if later review needs travel."},"clinic_checks":{"status":"ok","items":[{"id":"C1","text":"Ask whether follow-up care will be at the same facility as the procedure","scope":"treatment_abroad","source":{"url":"https://www.cdc.gov/yellow-book/hcp/health-care-abroad/medical-tourism.html","host":"cdc.gov","quote":"Medical tourists should also know whether follow-up care is scheduled to occur at the same facility as the procedure.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":403}},{"id":"C2","text":"Confirm the surgeon is trained and experienced in the exact procedure you are considering, not just in surgery 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risks","scope":"treatment_abroad","source":{"url":"https://www.orthoinfo.org/en/treatment/what-to-know-about-medical-tourism","host":"orthoinfo.org","quote":"Advertisements for these types of treatments often overestimate the benefits and underestimate the inherent risks or potential lack of effectiveness.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"F2","text":"Consultation offered only with sales staff, with no meeting with the surgeon","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/conditions/cosmetic-procedures/cosmetic-surgery-abroad/","host":"nhs.uk","quote":"make sure you have a consultation with the surgeon (avoid meetings only with sales people)","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"F3","text":"A request for payment before the patient has met the surgeon","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/conditions/cosmetic-procedures/cosmetic-surgery-abroad/","host":"nhs.uk","quote":"do not pay to see a surgeon you have not met","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"warning_signs":{"status":"ok","items":[{"id":"W1","text":"Severe pain or swelling","urgency":"contact_clinic","general":false,"source":{"url":"https://my.clevelandclinic.org/health/treatments/16796-bone-grafting","host":"my.clevelandclinic.org","quote":"Severe pain or swelling","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"W2","text":"Pus or drainage around the surgery site","urgency":"contact_clinic","general":false,"source":{"url":"https://my.clevelandclinic.org/health/treatments/16796-bone-grafting","host":"my.clevelandclinic.org","quote":"Infection signs like skin discoloration, pus, drainage or a feeling of warmth 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the home doctor which medicines to keep taking after discharge","document":"discharge medicine list","source":{"url":"https://www.orthoinfo.org/en/treatment/patient-guide-to-safe-surgery","host":"orthoinfo.org","quote":"The nurse will give you the highlights in writing, including a list of the medications you will need to take.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"T3","text":"Ask for written details of the procedure before you leave the hospital","document":"written procedure details","source":{"url":"https://rcseng.ac.uk/patient-care/cosmetic-surgery/after-surgery/","host":"rcseng.ac.uk","quote":"After your surgery, before you leave the hospital, ask for written information about the procedure you've had.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"alternatives":{"status":"ok","items":[{"id":"A1","text":"Your jawbone is short but you accept a higher failure risk","name":"Short dental implants","source":{"url":"https://cuh.nhs.uk/patient-information/sinus-lift-procedures","host":"cuh.nhs.uk","quote":"The risk of implant failure increases as the implant length decreases.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200},"operation_id":null},{"id":"A2","text":"Your sinus is close and you want to avoid a sinus lift","name":"Angled dental implants","source":{"url":"https://cuh.nhs.uk/patient-information/sinus-lift-procedures","host":"cuh.nhs.uk","quote":"Angled implants might be placed next to your sinus to avoid a sinus lift","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200},"operation_id":null},{"id":"A3","text":"You need to replace only one or two teeth","name":"Dental bridge","source":{"url":"https://cuh.nhs.uk/patient-information/sinus-lift-procedures","host":"cuh.nhs.uk","quote":"Usually only one or two teeth can be replaced on a 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bank.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},"recovery_daily":null},{"id":"xenograft-or-synthetic-substitute","name":"Xenograft or synthetic substitute","how_it_works":null,"recovery_daily":null}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1}}},"hrefLanguages":[{"rel":"alternate","hreflang":"ru","language":"ru","href":"https://ru.bookimed.com/clinics/country=mexico/city=puerto-valarta/procedure=kostnaa-plastika/"}],"questionsAndAnswers":[],"seoTests":{"thin_content":false,"no_txt_after_3_clinics":false},"offerFilters":{"offer_count":0,"price_filter":{"from":0,"to":0,"avg":0}},"leadsCount":{"leads_count":45},"manualSeo":[],"updatedAt":"2026-11-11T20:13:19.000Z","activeCountries":["MX","US","TR","TH"],"hasVideoReviewsByContext":false,"hasCriticalApiFallback":false}