{"meta":{"humanUrl":"https://us-uk.bookimed.com/clinics/country=united-states/city=cleveland/procedure=car-t-cell-therapy/best/","canonicalUrl":"https://us-uk.bookimed.com/clinics/country=united-states/city=cleveland/procedure=car-t-cell-therapy/best/","jsonUrl":"https://us-uk.bookimed.com/clinics/country=united-states/city=cleveland/procedure=car-t-cell-therapy/best/data.json","title":"Best clinics for CAR T-cell therapy in United States of America — Ratings & Reviews | Bookimed","description":"1 top-rated clinics for CAR T-cell therapy in United States of America. Compare rankings, prices, and patient reviews on Bookimed.","heading":"Best clinics for CAR T-cell therapy in United States of America","locale":"en","schemaVersion":"ClinicBestPageDataV1","snapshotId":"d3cde53d-d6ca39f2","contentVersion":"d3cde53d","generatedAt":"2026-11-13T11:21:00.110Z"},"filters":{"country":"united-states","city":"cleveland","procedure":"car-t-cell-therapy","page":1},"pagination":{"page":1,"totalCount":1,"totalPages":1},"breadcrumbs":[{"name":"Home","url":"/"},{"name":"Clinics","url":"/clinics/"},{"name":"United States of America","url":"/clinics/country=united-states/"},{"name":"Cleveland","url":"/clinics/country=united-states/city=cleveland/"},{"name":"CAR T-cell therapy","url":"/clinics/country=united-states/procedure=car-t-cell-therapy/"},{"name":"Best","url":"/clinics/country=united-states/city=cleveland/procedure=car-t-cell-therapy/best/"}],"entities":[{"name":"United States of America","alias":"united-states","type":"country","id":44},{"name":"Cleveland","alias":"cleveland","type":"city","id":102},{"name":"CAR T-cell therapy","alias":"car-t-cell-therapy","type":"procedure","id":800}],"clinics":{"clinics":[{"text":"<p>Cleveland Clinic is a nonprofit multispecialty academic healthcare system in Cleveland, Ohio. It offers adult and pediatric care across 12 specialized institutes. Key departments include heart surgery, neurology, and oncology. The clinic was founded in 1921. It now employs over 50,000 people across its global network, with hospitals in London, Abu Dhabi, and Canada.</p><p>The Neurological Institute treats over 140,000 patients each year. The Heart and Vascular program manages over 900,000 visits annually. Surgical teams perform more than 200,000 procedures each year. The nursing practice holds the Magnet designation for excellence. Its cancer program is accredited by the American College of Surgeons. International patients get help through a dedicated Global Patient Services department.</p>","text_type":"short_description","agency_settings":[{"setting_name":"is_new","setting_value":"0"},{"setting_name":"kids_only","setting_value":"0"}],"procedure_prices":[{"prices":{"price_from":400,"price_to":0,"currency":"USD","id":40450},"diagnostic":{"id":93,"name":"Tumor Marker Blood Test","alias":"identification-of-tumor-markers"}},{"prices":{"price_from":350,"price_to":0,"currency":"USD","id":36145},"diagnostic":{"id":96,"name":"CT (computer tomography)","alias":"ct"}}],"reviews":[],"clinic":{"id":80,"alias":"cleveland-clinic","name":"Cleveland Clinic","short_description":"<p>Cleveland Clinic is a nonprofit multispecialty academic healthcare system in Cleveland, Ohio. It offers adult and pediatric care across 12 specialized institutes. Key departments include heart surgery, neurology, and oncology. The clinic was founded in 1921. It now employs over 50,000 people across its global network, with hospitals in London, Abu Dhabi, and Canada.</p><p>The Neurological Institute treats over 140,000 patients each year. The Heart and Vascular program manages over 900,000 visits annually. Surgical teams perform more than 200,000 procedures each year. The nursing practice holds the Magnet designation for excellence. Its cancer program is accredited by the American College of Surgeons. International patients get help through a dedicated Global Patient Services department.</p>","images":[{"base_url":"clinic/6a78129a14470","title":"Cleveland Clinic hospital exterior with emergency entrance, USA"},{"base_url":"clinic/6a78129bcf8d1","title":"Cleveland Clinic Taussig Cancer Center modern glass building in Cleveland, USA"},{"base_url":"clinic/6a78129df2450","title":"Cleveland Clinic Taussig Cancer Center modern glass building exterior in Cleveland"},{"base_url":"clinic/6a78129fee224","title":"Cleveland Clinic modern glass facade with landscaped pond in Cleveland, USA"}],"flags":[{"name":"is_hide","value":false},{"name":"has_active_agencies","value":false}],"geo":{"country":{"name":"United States of America","id":44,"alias":"united-states","iso_code":"US"},"city":{"name":"Cleveland","id":102,"alias":"cleveland"},"address":"9500 Euclid Ave, Cleveland, OH 44195"},"rating":{"rating":4.8,"google":3.4,"percent_of_satisfied_clients":98},"statistics":{"number_of_reviews":4,"doctors_number":2,"year_foundation":1921},"accreditations":[{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/6194fa5077fec.jpeg","name":"Accreditation Canada Diamond Status Level ","country_code":"CA"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/619b4c38f036b.jpeg","name":"QHA Trent Accreditation","country_code":"GB"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/636103a731801.jpeg","name":"World's Best Hospitals 2022 by Newsweek","country_code":"US"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/6360fa074cde8.jpeg","name":"World's Best Smart Hospitals 2023 by Newsweek","country_code":"US"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/5d88caba297f8.jpeg","name":"Fellow, American College of Surgeons","country_code":"US"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/61779fac22b09.jpeg","name":"Given to the doctor International Society of Aesthetic Plastic Surgery (ISAPS) Сertificate ","country_code":"US"}],"agency_settings":[{"setting_name":"is_new","setting_value":"0"},{"setting_name":"kids_only","setting_value":"0"}]}}],"meta":{"total_count":1,"total_pages":1}},"clinicsMeta":{"total_count":1,"total_pages":1},"clinicsCount":1,"clinicsCountByEntity":{"clinic_count":29},"doctors":{"doctors":[],"meta":{"total_count":0,"total_pages":1}},"offers":{"cards":[{"image_count":0,"images":[],"offer":{"id":"68f8b8d472bb9e02c5086eb5","name":"CAR T-cell Therapy by Mayo Clinic-Trained Hematologist at JCI Center","type":"procedure","tags":[],"for_who":"<ul>\n<li>Omur Gokmen Sevindik has published 18 articles in international peer-reviewed journals on hematology and related fields.</li>\n<li>Istanbul Florence Nightingale Hospital is Turkey's first smart-and-green hospital with TÜV Hessen Green Building certification.</li>\n<li><strong>Included Services:</strong> Consultation with a hematologist, blood tests, 24-hour nurse services, VIP transfer (all airport, hotel, and clinic transfers).</li>\n<li><strong>Stay Info:</strong> 28 days hospital room stay included; hotel accommodation is not included in the price.</li>\n</ul>","country_text":"<p>Professor Omur Gokmen Sevindik, who completed a hematology fellowship at the Mayo Clinic, leads this treatment. The package costs approximately _offer_price_ – covering the entire 28-day inpatient cycle, all meals, and accommodation for one companion at the JCI-accredited <a href='https://us-uk.bookimed.com/clinic/group-florence-nightingale-hospitals/procedure=car-t-cell-therapy/'>Istanbul Florence Nightingale Hospital</a>. This TÜV Hessen-certified smart hospital provides dedicated nursing and multi-language support. Patients should plan to stay in Istanbul for at least two months following discharge for monitoring.</p>","clinic_entity_text":"<p>Prof. Ömür Gökmen Sevindik has _doctor_8431_years_ of hematology experience, including training at Mayo Clinic and 300+ academic works. CAR-T therapy may cost around $200,000 – typically covering cell collection, lab processing, 28-day hospitalization, and follow-up. The JCI-accredited hospital features Turkey's first EOS radiation-reducing imaging and provides full monitoring during treatment. Prof. Sevindik chairs the Multiple Myeloma Scientific Subcommittee and has performed numerous stem cell transplantations.</p><doctor id=\"8431\"></doctor>","package_price":200000,"actual_price":200000,"calculated_price":{"from":0,"to":0},"currency":{"code":"USD","symbol":"$","name":"Доллар","rate":1},"doctors":[{"id":8431,"name":"Omur Gokmen Sevindik","alias":"omur-gokmen-sevindik","photo":"doctor/66def09e516f0","first_year_working":2014,"short_description":"<p>Dr. Omur Gokmen Sevindik is a hematologist at Istanbul Florence Nightingale Hospital. He completed a fellowship at the Mayo Clinic, a top-ranked medical center in the US. Dr. Sevindik specializes in treating blood cancers like leukemia and lymphoma. He works at a JCI-accredited facility that treats 300,000 patients annually.</p><ul><li>Performs allogeneic and haploidentical stem cell transplantations.</li><li>Authored 18 articles in international peer-reviewed journals.</li><li>Presented research findings at over 25 international scientific conferences.</li><li>Treats complex conditions including myeloma, aplastic anemia, and thrombocytopenia.</li></ul>","specialities":[{"id":"hmt.001","name":"Hematologist","illness_kind_id":20},{"id":"onc.007","name":"Hematologist/oncologist","illness_kind_id":20}],"statistics":{"review_count":0,"review_score":0}}],"clinic":{"id":2943,"alias":"group-florence-nightingale-hospitals","name":"Istanbul Florence Nightingale Hospital","short_description":"<p>Istanbul Florence Nightingale Hospital is Turkey's first Smart-and-Green hospital, certified by TÜV Hessen. It holds JCI and ISO accreditation and treats over 300,000 patients each year. Its strongest specialty is orthopedics, with the first EOS device in Turkey for low-dose imaging.</p> <ul> <li>Heliport enables air ambulance transfers for emergency cases.</li> <li>All 11 surgery rooms have laminar airflow for sterile conditions.</li> <li>A 300-seat conference room connects to surgery rooms for live teaching.</li> <li>Accredited by British QHA, adding another layer of quality assurance.</li> <li>Part of the Florence Nightingale Group, which runs Demiroglu Bilim University and its medical school.</li> </ul>","images":[{"base_url":"clinic/67dbfda8d3883","title":"Istanbul Florence Nightingale Hospital modern clinic building exterior"}],"flags":[{"name":"is_hide","value":false},{"name":"has_active_agencies","value":true}],"geo":{"country":{"name":"Turkey","id":46,"alias":"turkey","iso_code":"TR"},"city":{"name":"Istanbul","id":107,"alias":"istanbul"},"address":"Hürriyet, Abide-i Hürriyet Cd No:166, 34403 Kâğıthane/İstanbul, Turkey"},"rating":{"rating":5,"google":3.6,"percent_of_satisfied_clients":98},"statistics":{"number_of_reviews":58},"accreditations":[{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/5cfa0ad8c533a.jpeg","name":"Joint Commission International ","country_code":"US"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/5db982e01da4b.jpeg","name":"International Organization for Standardization","country_code":"CH"}]}}},{"image_count":0,"images":[],"offer":{"id":"68f8d02f9b859e8a9803799c","name":"CAR T-cell Therapy by SIOP & EBMT-Certified Hematologist — Full Package","type":"procedure","tags":[],"for_who":"<ul>\n<li>Ceyhun Bozkurt is the clinical director of the pediatric hematology-oncology clinic and vice director of the stem cell transplant unit at Medical Park Bahcelievler Hospital.</li>\n<li>Medical Park Bahcelievler Hospital serves patients from Europe, the Commonwealth, the USA, Canada, Australia, and CIS countries.</li>\n<li><strong>Included Services:</strong> Full board, biopsy, radiologist consultation, cardiologist consultation, hematologist consultation, oncologist consultation, PET/CT, ECG mapping, chest X-ray, blood tests, 24-hour nurse services, hospitalization, airport-hotel-clinic-airport transfers.</li>\n<li><strong>Stay Info:</strong> 28 days hospital room stay included, no hotel stay included.</li>\n</ul>","country_text":"<p>This package provides personalized CAR-T cell dosing tailored to a patient's specific disease progression. Professor Ceyhun Bozkurt, a published SIOP/EBMT member with expertise in childhood blood disorders, leads the full-cycle management at <a href='https://us-uk.bookimed.com/clinic/medical-park-bahcelievler-hospital/procedure=car-t-cell-therapy/'>Medical Park Bahcelievler Hospital</a>. The approximate _offer_price_ fee covers a 28-day hospital stay in infection-controlled rooms with 24/7 monitoring. CAR-T cells are produced at the GMP-certified Acıbadem Labcell laboratory for safety. A bridge therapy option allows for continuous medical supervision prior to infusion if needed.</p>","package_price":300000,"actual_price":300000,"calculated_price":{"from":0,"to":0},"currency":{"code":"USD","symbol":"$","name":"Доллар","rate":1},"doctors":[{"id":8094,"name":"Ceyhun Bozkurt","alias":"ceyhun-bozcurt","photo":"doctor/668d17dca25a1","first_year_working":1990,"short_description":"<p>Dr. Ceyhun Bozkurt is a pediatric hematologist-oncologist at Medical Park Bahcelievler Hospital. He serves as the clinical director and vice director of the stem cell transplant unit. Dr. Bozkurt focuses on childhood leukemia, bone marrow transplants, and neuroblastoma. He completed specialized observerships at Harvard University and Cincinnati Children's Hospital.</p><ul><li>Member of the International Society of Pediatric Oncology (SIOP).</li><li>Active member of the European Bone Marrow Transplant Group (EBMT).</li><li>Published more than 40 articles on stem cell therapy and blood disorders.</li><li>Works at a center performing the highest number of transplants in Turkey.</li></ul>","specialities":[{"id":"ped.005","name":"Pediatric hematologist/oncologist","illness_kind_id":20}],"statistics":{"review_count":0,"review_score":0,"operations_performed_count":0}}],"clinic":{"id":5611,"alias":"medical-park-bahcelievler-hospital","name":"Medical Park Bahcelievler Hospital","short_description":"<p>Medical Park Bahcelievler Hospital is a JCI-accredited university hospital affiliated with Altınbaş University. It serves as a national reference center for cardiovascular surgery and intensive care. Its main specialties are cardiology, oncology, bone marrow transplantation, and pediatrics.</p> <ul> <li>Performed the highest number of bone marrow transplants in Turkey over the past two years.</li> <li>Collaborates with international bone marrow registries EBMT, CIBMTR, and ISCT.</li> <li>Offers minimally invasive heart surgery and Deep Brain Stimulation for Parkinson's.</li> <li>On-site imaging includes PET/CT, 64-slice CT, 3 Tesla MRI, and 4D ultrasound.</li> </ul>","images":[{"base_url":"clinic/668692e0d2c17","title":"Medical Park Bahcelievler Hospital modern glass facade in Istanbul, Turkey"}],"flags":[{"name":"has_active_agencies","value":true},{"name":"is_hide","value":false}],"geo":{"country":{"name":"Turkey","id":46,"alias":"turkey","iso_code":"TR"},"city":{"name":"Istanbul","id":107,"alias":"istanbul"},"address":"Turkey, Istanbul, "},"rating":{"rating":0,"google":4.5,"percent_of_satisfied_clients":0},"statistics":{"number_of_reviews":0},"accreditations":[]}}}],"metadata":{"total_count":2}},"listingTexts":{"entity_texts":{},"texts":{}},"relations":{"countries":[{"name":"Austria","alias":"austria","iso_code":"AT"},{"name":"China","alias":"china","iso_code":"CN"},{"name":"Germany","alias":"germany","iso_code":"DE"},{"name":"Israel","alias":"israel","iso_code":"IL"},{"name":"Italy","alias":"italy","iso_code":"IT"},{"name":"Lithuania","alias":"lithuania","iso_code":"LT"},{"name":"Republic of Korea","alias":"republic-of-korea","iso_code":"KR"},{"name":"Spain","alias":"spain","iso_code":"ES"},{"name":"Turkey","alias":"turkey","iso_code":"TR"},{"name":"United Kingdom","alias":"united-kingdom","iso_code":"GB"},{"name":"United States of America","alias":"united-states","iso_code":"US"}],"cities":[{"name":"Cleveland","alias":"cleveland"}],"operations":[{"name":"Chemotherapy","alias":"chemotherapy"},{"name":"CAR T-cell therapy","alias":"car-t-cell-therapy"}],"diagnostics":[{"name":"MRI of one area","alias":"mri-one-department"},{"name":"Ultrasound","alias":"u.s."},{"name":"Biopsy","alias":"biopsy"},{"name":"Complete blood count","alias":"total-blood"},{"name":"Tumor Marker Blood Test","alias":"identification-of-tumor-markers"},{"name":"CT (computer tomography)","alias":"ct"},{"name":" Сomplex oncology diagnostic","alias":"somplex-oncology-diagnostic"},{"name":"CT of the paranasal sinuses","alias":"ct-of-the-paranasal-sinuses"}],"illnesses":[{"name":"Lymphoma","alias":"lymphoma"},{"name":"Hodgkin's lymphoma","alias":"hodgkin-s-disease"},{"name":"Myeloma","alias":"myeloma"}],"illnessKinds":[{"name":"Hematology Oncology","alias":"hematology"}],"illness_kinds":[{"name":"Hematology Oncology","alias":"hematology"}]},"popularSearches":[{"name":"Chemotherapy","alias":"chemotherapy","type":"operation","id":37},{"name":"Bone marrow transplantation","alias":"bone-marrow-transplantation","type":"operation","id":141},{"name":"Plasmapheresis","alias":"plasmapheresis","type":"operation","id":386},{"name":"CAR T-cell therapy","alias":"car-t-cell-therapy","type":"operation","id":800},{"name":"Biological therapy","alias":"biological-therapy","type":"operation","id":154},{"name":"Ultrasound","alias":"u.s.","type":"diagnostic","id":37},{"name":"MRI of one area","alias":"mri-one-department","type":"diagnostic","id":6},{"name":"Consultation with creation of treatment plan ","alias":"consultation-with-creation-of-treatment-plan","type":"diagnostic","id":457},{"name":"CT (computer tomography)","alias":"ct","type":"diagnostic","id":96},{"name":"Complete blood count","alias":"total-blood","type":"diagnostic","id":83},{"name":"Leukemia","alias":"leukemia","type":"illness","id":393},{"name":"Lymphoma","alias":"lymphoma","type":"illness","id":12},{"name":"Aplastic anemia","alias":"aplastic-anemia","type":"illness","id":319},{"name":"Myeloma","alias":"myeloma","type":"illness","id":126},{"name":"Acute lymphoblastic leukemia","alias":"acute-lymphoblastic-leukemia","type":"illness","id":492}],"operationPrices":{"operation_prices":{"800":{"operation":{"name":"CAR T-cell therapy","alias":"car-t-cell-therapy","use_for_listing":true},"country_price":{"US":{"amount":420000,"max_amount":540000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"TR":{"amount":150000,"max_amount":220000,"currency":"USD","clinic_count":3,"price_kind":"from_range","price_source":"mixed","scope":"country"},"TH":{"amount":150000,"max_amount":220000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"AT":{"amount":280000,"max_amount":365000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"}},"available_clinics":{"UA":false,"FR":false,"GB":false,"US":false,"IL":true,"TR":true,"MX":false,"DE":false,"CA":false,"AE":false,"TH":false,"PL":false,"KR":false,"CZ":false,"AT":false,"ES":true,"IT":true,"CN":true,"AU":false,"IN":false,"MY":false,"VN":false,"BR":false},"description":"<p>This therapy modifies patient\"s cells to combat cancer, merging immunology and genetics. It\"s precise, powerful, potentially one-off treatment.</p>"},"1699":{"operation":{"name":"CAR-T for DLBCL","alias":"car-t-for-dlbcl","use_for_listing":false},"country_price":{"US":{"amount":420000,"max_amount":530000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"TR":{"amount":140000,"max_amount":190000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"TH":{"amount":185000,"max_amount":250000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"AT":{"amount":290000,"max_amount":380000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"}},"available_clinics":{"US":false,"TR":false,"TH":false,"AT":false}},"1700":{"operation":{"name":"CAR-T for Multiple Myeloma","alias":"car-t-for-multiple-myeloma","use_for_listing":false},"country_price":{"US":{"amount":420000,"max_amount":540000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"TR":{"amount":140000,"max_amount":190000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"TH":{"amount":200000,"max_amount":280000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"AT":{"amount":330000,"max_amount":430000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"}},"available_clinics":{"US":false,"TR":false,"TH":false,"AT":false}},"1702":{"operation":{"name":"CAR-T for Pediatric ALL","alias":"car-t-for-pediatric-all","use_for_listing":false},"country_price":{"US":{"amount":475000,"max_amount":650000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"TR":{"amount":140000,"max_amount":220000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"TH":{"amount":200000,"max_amount":280000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"AT":{"amount":290000,"max_amount":390000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"}},"available_clinics":{"US":false,"TR":false,"TH":false,"AT":false}}}},"operationIndicators":{"details":{"anesthesia":"general","days_in_clinic":7,"days_in_country":14,"rehabilitation_days":30,"satisfied_percent":78,"treatment_duration_hours":4},"illness_kind_details":{"requests_processed":6882}},"direction":{"id":20,"name":"Hematology Oncology","alias":"hematology"},"illness_kind":{"id":20,"name":{"en":"Hematology Oncology"}},"parsed_details":{"procedure_type":"therapy","fields":{"anesthesia":["none"],"back_to_work_days":{"min":60,"max":90,"unit":"days","qualifier":"Desk work usually resumes at 2–3 months, once CRS/ICANS risk and cytopenias settle. Later if fatigue, neurotoxicity or infections persist."},"complication_rate_pct":{"min":50,"max":95,"unit":"percent","qualifier":"Any-grade cytokine release syndrome or neurotoxicity within about 8 weeks; severe grade 3+ events roughly 10-25%."},"contraindications":["Active uncontrolled infection, including uncontrolled hepatitis B/C or HIV","Significant cardiac, pulmonary, renal or hepatic dysfunction","Active CNS or autoimmune neurological disease (relative, product-dependent)","Poor performance status or rapid progression during manufacturing (relative)","Severe hypersensitivity to DMSO or product excipients","Pregnancy or breastfeeding","Active uncontrolled graft-versus-host disease (relative, prior transplant)"],"days_in_clinic":{"min":10,"max":21,"unit":"nights","qualifier":"Inpatient stay with daily CRS/ICANS monitoring, about 2 weeks; longer if ICU needed."},"diagnostic_duration_minutes":null,"diagnostic_preparation":null,"diagnostic_referral_needed":null,"diagnostic_result_time_hours":null,"exercise_resume_weeks":{"min":8,"max":12,"unit":"weeks","qualifier":"Strenuous exercise waits about 2–3 months, until counts recover and early neurotoxicity and infection risk passes. Light walking earlier."},"final_result_months":{"min":1,"max":3,"unit":"months","qualifier":"Response is assessed at about 1 month and 3 months after infusion; remission durability needs longer follow-up."},"fly_home_after_days":{"min":28,"max":42,"unit":"days","qualifier":"Stay near the centre at least 4 weeks, past peak CRS/ICANS risk. Fly if no toxicity, counts acceptable."},"follow_up_visits":[{"purpose":"assessment","requirement":"routine","after":{"min":7,"max":14,"unit":"days","qualifier":"Frequent early monitoring for cytokine release syndrome and neurotoxicity if discharged"}},{"purpose":"result_review","requirement":"routine","after":{"min":28,"max":35,"unit":"days","qualifier":"First response assessment, about day 28-35 after infusion"}},{"purpose":"result_review","requirement":"routine","after":{"min":85,"max":100,"unit":"days","qualifier":"Response reassessment about day 85-100 (around 3 months) after infusion"}}],"indications":["Relapsed or refractory large B-cell lymphoma","Relapsed or refractory B-cell acute lymphoblastic leukemia","Relapsed or refractory follicular and mantle cell lymphoma","Relapsed or refractory multiple myeloma (BCMA-directed)","Relapsed or refractory chronic lymphocytic leukemia"],"main_risks":["Cytokine release syndrome","Immune effector cell-associated neurotoxicity syndrome","Prolonged cytopenias","Infections and hypogammaglobulinemia","B-cell aplasia","Hemophagocytic lymphohistiocytic-like syndrome","Secondary T-cell malignancies (rare)","Tumor lysis syndrome","Infusion-related hypersensitivity reactions"],"pain":"The infusion itself is generally painless; fever, headache, body aches and malaise may occur with cytokine release, and leukapheresis involves line placement with mild discomfort.","preparation":["Specialist eligibility assessment and disease staging","Infection screening and organ function evaluation","Leukapheresis to collect the patient's T cells","Possible bridging therapy while the cells are manufactured (weeks)","Lymphodepleting chemotherapy a few days before infusion","Central venous access as needed","Arrange nearby accommodation and a caregiver after infusion","Confirm target antigen (e.g., CD19, BCMA) and prior-therapy eligibility","Pre-infusion premedication (paracetamol and antihistamine)","Access to tocilizumab and ICU-level support before infusion"],"recovery_timeline":[{"phase":"Infusion and first 1-2 weeks","description":"Single IV infusion followed by close monitoring for cytokine release syndrome and neurotoxicity, usually peaking in the first 1-2 weeks.","restrictions":["Stay near the treatment center"]},{"phase":"Weeks 2-4","description":"Discharge when stable, frequent visits, blood count and infection monitoring, first response assessment around day 28.","restrictions":["Stay near the treatment center until about day 28","No driving for at least 8 weeks","Avoid crowds and infection exposure"]},{"phase":"Months 2-12","description":"Gradual recovery of blood counts and energy, immune function monitoring, immunoglobulin replacement if needed, response reassessment.","restrictions":["Delay live vaccines per specialist advice"]}],"rehabilitation_days":{"min":60,"max":90,"unit":"days","qualifier":"Functional recovery after the 4-week monitoring period; slower with persistent fatigue, cytopenias, neurotoxicity or infections."},"result_longevity":"In large B-cell lymphoma, about 40% remain progression-free at 1 year; some stay in long-term remission. In B-ALL, about 36% relapse; CAR T cells can persist up to about 5 years.","revision_rate_pct":null,"scars":"There is no surgical incision, only small puncture marks from the leukapheresis or central venous line sites.","sessions_or_stages":{"sessions":{"min":1,"max":1,"unit":"visits","qualifier":"One CAR T-cell infusion; leukapheresis and lymphodepletion are preceding stages."},"stages":[{"code":"leukapheresis","label":"Leukapheresis to collect T cells","after":{"min":0,"max":0,"unit":"days","qualifier":"Starting point of the treatment pathway"}},{"code":"lymphodepletion","label":"Lymphodepleting chemotherapy","after":{"min":23,"max":58,"unit":"days","qualifier":"About 3-8 weeks after leukapheresis; 2-5 days before infusion"}},{"code":"car_t_infusion","label":"CAR T-cell infusion","after":{"min":28,"max":63,"unit":"days","qualifier":"Depends on manufacturing and product release time"}}],"qualifier":"Single-infusion therapy; timelines vary by product and center."},"success":{"metric":"Complete response rate in relapsed/refractory large B-cell lymphoma (3rd-line or later)","value":51,"unit":"percent","horizon":"Best response, typically assessed at 1-3 months after infusion","evidence_status":"limited","population":"Adults with relapsed/refractory LBCL after two or more prior lines"},"techniques":[{"name":"Autologous CD19-directed CAR T-cell therapy","suits_whom":"Relapsed/refractory B-cell lymphomas and B-ALL","recovery":"Inpatient monitoring about 10-21 days, then nearby follow-up to day 28."},{"name":"Autologous BCMA-directed CAR T-cell therapy","suits_whom":"Relapsed/refractory multiple myeloma after multiple prior lines","recovery":"Similar monitoring; prolonged cytopenias are common."}],"treatment_conditions":["inpatient"],"treatment_duration_hours":{"min":0.5,"max":1,"unit":"hours","qualifier":"Duration of the single CAR T-cell infusion itself; leukapheresis (about 3-6 hours) and lymphodepletion are separate."},"initial_assessment_documents":["Pathology report with CD19 or BCMA status","Summary of prior treatment lines and responses","Recent PET-CT or MRI report","Bone marrow biopsy report","Recent CBC, kidney and liver function tests","Echocardiogram report (if available)"],"travel_trips":{"min":1,"max":2,"one_trip_possible":true,"qualifier":"Cell collection, then 3-9 weeks manufacturing, usually at home; return for infusion and 4+ weeks nearby. One trip means staying."},"clinic_checks":{"status":"ok","items":[{"id":"C1","text":"Ask the clinic for examples of the practitioners' experience with the exact procedure you are planning","scope":"treatment_abroad","source":{"url":"https://travelaware.campaign.gov.uk/surgery-abroad-cut-out-the-risk/","host":"travelaware.campaign.gov.uk","quote":"Ask for examples of the practitioners’ experience with the surgery you are intending to have.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"C2","text":"Ask whether a doctor is always present in the clinic and whether a high dependency or intensive care unit exists","scope":"treatment_abroad","source":{"url":"https://www.bapras.org.uk/public/patient-information/cosmetic-surgery/cosmetic-surgery-abroad","host":"bapras.org.uk","quote":"Is there always a doctor in the clinic and is there a high dependency or intensive care unit?","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C3","text":"Confirm the surgeon is trained and experienced in the exact procedure you are considering, not just in surgery generally","scope":"treatment_abroad","source":{"url":"https://www.isaps.org/discover/patients-home/considering-your-procedure-abroad/finding-a-surgeon-abroad/","host":"isaps.org","quote":"Verify that the surgeon is trained and experienced in performing the procedure you are considering.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C4","text":"Check that the surgeon who consults with you is the same person who will carry out the procedure","scope":"treatment_abroad","source":{"url":"https://travelaware.campaign.gov.uk/surgery-abroad-cut-out-the-risk/","host":"travelaware.campaign.gov.uk","quote":"Check that the surgeon you consult with, will be the same person carrying out the procedure.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C5","text":"Decide before you travel where check-ups after the operation will take place, because follow-up abroad may be missing or weaker","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/conditions/cosmetic-procedures/cosmetic-surgery-abroad/","host":"nhs.uk","quote":"You need to think about where check-ups will take place.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"red_flags":{"status":"ok","items":[{"id":"F1","text":"Pressure to decide quickly, or cheap time-limited offers, is a warning sign of a clinic offer","scope":"treatment_abroad","source":{"url":"https://travelaware.campaign.gov.uk/surgery-abroad-cut-out-the-risk/","host":"travelaware.campaign.gov.uk","quote":"Don’t be pressured into quick decisions either through forceful persuasion or cheap, time limited offers.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"F2","text":"An advert or information that guarantees complete success should raise concerns","scope":"treatment_abroad","source":{"url":"https://travelaware.campaign.gov.uk/surgery-abroad-cut-out-the-risk/","host":"travelaware.campaign.gov.uk","quote":"Any advert or information that guarantees complete success should raise concerns.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"F3","text":"Forceful persuasion or cheap, time-limited offers pushing you into a quick decision","scope":"treatment_abroad","source":{"url":"https://travelaware.campaign.gov.uk/surgery-abroad-cut-out-the-risk/","host":"travelaware.campaign.gov.uk","quote":"Don’t be pressured into quick decisions either through forceful persuasion or cheap, time limited offers.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"warning_signs":{"status":"ok","items":[{"id":"W1","text":"Confusion or difficulty communicating","urgency":"emergency","general":false,"source":{"url":"https://www.cancer.gov/news-events/cancer-currents-blog/2019/cancer-immunotherapy-investigating-side-effects","host":"cancer.gov","quote":"Patients also may experience neurologic symptoms such as confusion, tremors, or difficulty communicating.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"W2","text":"Excessive sleepiness","urgency":"contact_clinic","general":false,"source":{"url":"https://www.cancer.gov/about-cancer/treatment/research/car-t-cells","host":"cancer.gov","quote":"Some of the hallmark signs of ICANS include confusion, excessive sleepiness, and impaired speech.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"W3","text":"Trouble breathing","urgency":"emergency","general":false,"source":{"url":"https://www.cancer.gov/about-cancer/treatment/side-effects/flu-symptoms","host":"cancer.gov","quote":"Immunotherapy treatments such as CAR T-cell therapy and some monoclonal antibodies may cause cytokine release syndrome (CRS), a condition that can lead to severe flu-like symptoms as well as a rash, rapid heartbeat, low blood pressure, and trouble breathing.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"W4","text":"Fever","urgency":"contact_clinic","general":true,"source":{"url":"https://www.cancer.gov/news-events/cancer-currents-blog/2019/cancer-immunotherapy-investigating-side-effects","host":"cancer.gov","quote":"Many patients who receive CAR T-cell therapy develop a condition known as cytokine release syndrome, which can cause a fever, fast heart rate, low blood pressure, and rash, among other symptoms.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"take_home":{"status":"ok","items":[{"id":"T1","text":"Shows emergency staff and other doctors the patient is a CAR T recipient","document":"car t wallet card","source":{"url":"https://www.mskcc.org/cancer-care/patient-education/car-cell-therapy-guide-adult-patients-caregivers","host":"mskcc.org","quote":"Carry your wallet card with you at all times.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"T2","text":"Home doctor needs the plan the treating team set for leaving hospital","document":"written discharge instructions","source":{"url":"https://www.mskcc.org/cancer-care/patient-education/car-cell-therapy-guide-adult-patients-caregivers","host":"mskcc.org","quote":"Your CAR T team will give you discharge instructions before you leave the hospital.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"T3","text":"Home doctor needs the exact medicines to continue treatment safely","document":"discharge medicines list","source":{"url":"https://www.cuh.nhs.uk/patient-information/discharge-advice-from-ward-c10c9-following-car-t-cell-therapy/","host":"cuh.nhs.uk","quote":"You will be given a copy of all the medications that you should take after being discharged.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"alternatives":{"status":"ok","items":[{"id":"A1","text":"You are older and not eligible for CAR T-cell therapy","name":"Bispecific antibody therapy","source":{"url":"https://www.cancer.gov/news-events/cancer-currents-blog/2022/tecvayli-multiple-myeloma","host":"cancer.gov","quote":"with bispecific antibodies you'll be able to treat older patients who are not eligible for CAR T-cell therapies","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200},"operation_id":null}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"technique_details":{"status":"ok","items":[{"id":"autologous-cd19-directed-car-t-cell","name":"Autologous CD19-directed CAR T-cell therapy","how_it_works":{"text":"Modified T cells recognize an antigen on cancer cells","source":{"url":"https://www.leedsth.nhs.uk/?p=50458","host":"leedsth.nhs.uk","quote":"These new receptors will enable the T-cells to recognise and attach to the antigen on the cancer cell.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},"recovery_daily":{"status":"missing","reason":"no_official_source"}},{"id":"autologous-bcma-directed-car-t-cell","name":"Autologous BCMA-directed CAR T-cell therapy","how_it_works":{"text":"Engineered cells are designed to recognize BCMA, a protein on myeloma cells","source":{"url":"https://www.cancer.gov/news-events/cancer-currents-blog/2021/fda-ide-cel-car-t-multiple-myeloma","host":"cancer.gov","quote":"genetic engineering lets the CAR T cells \"see\" BCMA, a protein that's present at high amounts in multiple myeloma cells","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},"recovery_daily":{"status":"missing","reason":"no_official_source"}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1}}},"hrefLanguages":[{"rel":"alternate","hreflang":"ru","language":"ru","href":"https://ru.bookimed.com/clinics/country=united-states/city=klivlend/procedure=car-t-kletocnaa-terapia/"}],"questionsAndAnswers":[],"seoTests":{"thin_content":false,"no_txt_after_3_clinics":false},"offerFilters":{"offer_count":0,"price_filter":{"from":0,"to":0,"avg":0}},"leadsCount":{"leads_count":51},"manualSeo":[],"updatedAt":"2026-11-01T20:23:30.987Z","activeCountries":["US","TR","AT","TH"],"hasVideoReviewsByContext":false,"hasCriticalApiFallback":false}