{"meta":{"humanUrl":"https://us-uk.bookimed.com/clinics/illness=sigmoid-adenocarcinoma/best/page=5/","canonicalUrl":"https://us-uk.bookimed.com/clinics/illness=sigmoid-adenocarcinoma/best/page=5/","jsonUrl":"https://us-uk.bookimed.com/clinics/illness=sigmoid-adenocarcinoma/best/page=5/data.json","title":"Best clinics for Sigmoid adenocarcinoma — Ratings & Reviews | Bookimed","description":"111 top-rated clinics. Compare rankings, prices, and patient reviews on Bookimed.","heading":"Best clinics for Sigmoid adenocarcinoma","locale":"en","schemaVersion":"ClinicBestPageDataV1","snapshotId":"5f19b2cd-a717cb9a","contentVersion":"5f19b2cd","generatedAt":"2026-11-15T09:09:29.116Z"},"filters":{"illness":"sigmoid-adenocarcinoma","page":5},"pagination":{"page":5,"totalCount":111,"totalPages":12},"breadcrumbs":[{"name":"Home","url":"/"},{"name":"Clinics","url":"/clinics/"},{"name":"Sigmoid adenocarcinoma","url":"/clinics/illness=sigmoid-adenocarcinoma/"},{"name":"Best","url":"/clinics/illness=sigmoid-adenocarcinoma/best/"},{"name":"Page 5","url":"/clinics/illness=sigmoid-adenocarcinoma/best/page=5/"}],"entities":[{"name":"Sigmoid adenocarcinoma","alias":"sigmoid-adenocarcinoma","type":"illness","id":360}],"clinics":{"clinics":[{"text":"<p>Prof. Elke Jaeger, a top oncologist for _doctor_502_years_ with 1,100+ procedures, leads at one of only 22 worldwide ESMO-certified centers. This clinic specializes in therapeutic anti-tumor vaccines. Video consultations cost around $1,360. The full diagnostic work-up including PET/CT and colonoscopy typically runs $5,880–7,000. Surgery may cost from $31,750 – that covers the procedure, the hospital stay, and full oncology team support.</p><doctor id=\"502\"></doctor>","text_type":"mt_wow_description","best_texts":{"techniques":"Surgical resection, chemotherapy, targeted therapy, focused ultrasound","good_fit_for":"Advanced sigmoid adenocarcinoma cases","why_its_ranked":"ESMO-certified oncology center with focused ultrasound capability. Ranked among top German hospitals for colon cancer treatment success. Offers personalized cancer vaccines and targeted therapy."},"agency_settings":[{"setting_name":"is_new","setting_value":"0"},{"setting_name":"kids_only","setting_value":"0"}],"procedure_prices":[{"prices":{"price_from":500,"price_to":1300,"currency":"USD","id":13900},"diagnostic":{"id":96,"name":"CT (computer tomography)","alias":"ct"}},{"prices":{"price_from":500,"price_to":1500,"currency":"USD","id":13389},"diagnostic":{"id":39,"name":"Biopsy","alias":"biopsy"}}],"reviews":[],"clinic":{"id":136,"alias":"clinic-nordwest","name":"Nordwest Clinic (Krankenhaus)","short_description":"<p>Nordwest Clinic is a German hospital that developed innovations like 3D ultrasound and anticancer vaccines. Its main specialties are oncology, orthopedics, cardiology, neurology, gynecology, urology, and surgery. Named a TOP German hospital by Focus and among the World's Best Hospitals by Newsweek.</p> <ul> <li>Oncology and Hematology Center is ESMO-certified – only 22 clinics worldwide hold this status.</li> <li>Only certified center in the region for focused ultrasound (FUS), recognized by Time magazine as a top invention.</li> <li>Comprises 5 research institutes, 11 specialized clinics, and 17 certified centers.</li> <li>Treats over 60,000 patients annually with 286 doctors across 28 departments.</li> <li>Single wards with WiFi, TV, and meals. Translation services provided for international patients.</li> </ul>","images":[{"base_url":"clinic/5c87d1969700b","title":"Nordwest Clinic hospital building exterior in Frankfurt, Germany"},{"base_url":"clinic/5ac32d5931619","title":"Hospital corridor at Nordwest Clinic Frankfurt with modern medical equipment"},{"base_url":"clinic/5ac32d5f7cbdc","title":"Radiotherapy room at Nordwest Clinic with patient and medical staff"},{"base_url":"clinic/5ac32d5a4925b","title":"Intensive care unit at Nordwest Clinic with medical staff and monitoring equipment"}],"flags":[{"name":"is_hide","value":false},{"name":"has_active_agencies","value":false}],"geo":{"country":{"name":"Germany","id":22,"alias":"germany","iso_code":"DE"},"city":{"name":"Frankfurt am Main","id":354,"alias":"frankfurt-am-main"},"address":"Steinbacher Hohl 2-26, 60488 Frankfurt am Main, Germany"},"rating":{"rating":4.5,"google":4,"percent_of_satisfied_clients":91},"statistics":{"number_of_reviews":57,"doctors_number":286,"year_foundation":1963},"accreditations":[{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/5ceb72be5c3ae.jpeg","name":"TÜV AG Сompany Research & Investing Certificate","country_code":"DE"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/5ceb72d2c6a2f.jpeg","name":"TOP German hospital according to 2019 Focus ranking","country_code":"DE"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/609cdeda74941.jpeg","name":"World's Best Hospitals 2021 by Newsweek","country_code":"US"}],"agency_settings":[{"setting_name":"is_new","setting_value":"0"},{"setting_name":"kids_only","setting_value":"0"}]}},{"text":"<p>Assoc. Prof. Serap Kaya is a colorectal cancer specialist, a medical oncologist trained at Marmara University and Kocaeli University. A comprehensive diagnostic package costs around $2,950 and includes consultations, genetic testing, and a week's accommodation. Laparoscopic colectomy surgery may cost between $11,000 and $16,000. The JCI-accredited Emsey Hospital is a Eurospine Centre of Excellence with Johns Hopkins affiliation.</p>","text_type":"mt_wow_description","best_texts":{"techniques":"Radiotherapy with LINAC Trilogy Device (IMRT, SRS, VMAT, IGRT, EBRT), nuclear medicine therapies (PSMA, DSMA, DOTA TATE PET, iodine therapy, actinium therapy, lutetium therapy), genetic testing (KRAS, NRAS)","good_fit_for":"Advanced colorectal cancers","why_its_ranked":"Offers advanced radiotherapy and nuclear medicine therapies for colorectal cancers. JCI-accredited facility with specialized oncology team. Includes genetic testing for personalized treatment planning."},"agency_settings":[{"setting_name":"is_new","setting_value":"0"},{"setting_name":"kids_only","setting_value":"0"}],"procedure_prices":[{"prices":{"price_from":9000,"price_to":19000,"currency":"USD","id":32722},"operation":{"id":448,"name":"Colectomy (large bowel resection)","alias":"colectomy-large-bowel-resection"}},{"prices":{"price_from":1500,"price_to":1500,"currency":"USD","id":32820},"diagnostic":{"id":39,"name":"Biopsy","alias":"biopsy"}},{"prices":{"price_from":750,"price_to":950,"currency":"USD","id":50789},"diagnostic":{"id":1,"name":"PET/CT","alias":"pet-ct"}}],"reviews":[],"clinic":{"id":1173,"alias":"emsey-hospital","name":"Emsey Hospital","short_description":"<p>Emsey Hospital is a multi-specialty medical center on the Asian side of Istanbul. It is the first hospital to receive the International Health Tourism Authorization Certificate (001) from the Turkish Ministry of Health. The hospital is especially known for orthopedics, spine surgery, bone marrow transplantation, and oncology.</p> <ul> <li>First EUROSPINE-certified Surgical Spine Centre of Excellence in Turkey and Asia.</li> <li>One of the largest bone marrow transplant units in the region with 45 beds.</li> <li>JCI-accredited since 2017, also holds ISO 9001 and TÜSKA certificates.</li> <li>Offers PET-CT, 3 Tesla MRI, LINAC Trilogy, and nuclear medicine therapies.</li> <li>Provides airport transfers, interpreters, and accommodation for international patients.</li> </ul>","images":[{"base_url":"clinic/6149da44dd434","title":"Modern exterior of Emsey Hospital in Istanbul, Turkey, multi-story medical facility"},{"base_url":"clinic/616d78db4d7c0","title":"Modern reception area at Emsey Hospital with spacious medical facility interior"},{"base_url":"clinic/616d7a18a32f4","title":"Patient room at Emsey Hospital with hospital bed, sofa, and modern furnishings"},{"base_url":"clinic/616fd327b31e4","title":"Multidisciplinary tumor board meeting at Emsey Hospital with doctors reviewing scans"}],"flags":[{"name":"is_hide","value":false},{"name":"has_active_agencies","value":false}],"geo":{"country":{"name":"Turkey","id":46,"alias":"turkey","iso_code":"TR"},"city":{"name":"Istanbul","id":107,"alias":"istanbul"},"address":"Çamlık, Selçuklu Cd. No:22, 34912 Pendik/İstanbul, Turkey"},"rating":{"rating":4.1,"google":3.4,"percent_of_satisfied_clients":69},"statistics":{"number_of_reviews":42,"doctors_number":88,"year_foundation":2012},"accreditations":[{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/5d10bd3ab2720.jpeg","name":"The Baby-friendly Hospital Initiative (BFHI) by WHO and UNICEF"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/60d48fc833289.jpeg","name":"Turkish Medical Association","country_code":"TR"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/5ceb725c9b963.jpeg","name":"TEMOS International Healthcare Accreditation","country_code":"DE"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/5ceb725522d15.jpeg","name":"Certification according to DIN EN ISO 9001 by TÜV NORD CERT","country_code":"DE"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/62e2ea948b5d5.jpeg","name":"International Health Tourism Authorization Certificate","country_code":"TR"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/5db982e01da4b.jpeg","name":"International Organization for Standardization","country_code":"CH"}],"agency_settings":[{"setting_name":"is_new","setting_value":"0"},{"setting_name":"kids_only","setting_value":"0"}]}},{"text":"<p>Colectomy follows strict cancer surgery criteria: 5–10 cm tumor-free margins and at least 12 lymph nodes dissected. Hospital Galenia’s Digestive Tumors and Minimally Invasive Clinic offers open and laparoscopic approaches, within a JCI- and Qmentum Diamond-accredited hospital. Liver biopsy may cost around $2,000, while colorectal diagnosis may run $3,000–$3,100. Colectomy may cost around $25,000–$35,000, including resection and lymph node dissection; flights and accommodation outside the hospital stay are excluded.</p>","text_type":"mt_wow_description","best_texts":{"techniques":"Colectomy, liver resection, laparoscopic surgery, open surgery, lymph node dissection","good_fit_for":"Colon resection removing at least 12 lymph nodes","why_its_ranked":"Dedicated digestive tumor clinic offers open and laparoscopic colectomy with 5–10 cm tumor-free margins and 12+ lymph nodes; team certified by Mexican Society of Oncology. 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The hospital treats around 10,000 patients each year, many coming from the US and Canada.</p> <ul> <li>Holds Accreditation Canada Diamond Status for quality and safety.</li> <li>Offers breast-conserving surgery alongside mastectomy procedures.</li> <li>200 physicians across 10 departments provide adult-only care.</li> <li>Serves a diverse international patient base from Latin America, Australia, and Europe.</li> </ul>","images":[{"base_url":"clinic/68aa61a7ecb82","title":"Modern facade of Galenia Hospital in Cancun, Mexico"},{"base_url":"clinic/68aa62231d8c7","title":"Galenia Hospital modern clinic exterior in Cancun, Mexico"},{"base_url":"clinic/68aa622a9d841","title":"Galenia Hospital exterior illuminated at night in Mexico"},{"base_url":"clinic/68aa6231a17e9","title":"Modern exterior of Galenia Hospital in Cancun, Mexico"}],"flags":[{"name":"has_active_agencies","value":false},{"name":"is_hide","value":false}],"geo":{"country":{"name":"Mexico","id":40,"alias":"mexico","iso_code":"MX"},"city":{"name":"Cancún","id":454,"alias":"cancun"},"address":"Cancun 28, Mercado, 77516 Soledad de Graciano Sánchez, Q.R., Mexico"},"rating":{"rating":4,"google":3.2,"percent_of_satisfied_clients":98},"statistics":{"number_of_reviews":1,"doctors_number":200,"year_foundation":2006},"accreditations":[{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/5cfa0ad8c533a.jpeg","name":"Joint Commission International ","country_code":"US"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/6194fa5077fec.jpeg","name":"Accreditation Canada Diamond Status Level ","country_code":"CA"}],"agency_settings":[{"setting_name":"is_new","setting_value":"0"},{"setting_name":"kids_only","setting_value":"0"}]}},{"text":"<p>Interbalkan European Medical Center is a multidisciplinary hospital linked with Massachusetts General Hospital and Harvard University. It specializes in robotic surgery, cardiac surgery, neurosurgery, and oncology. The center belongs to Athens Medical Group, Greece's largest hospital network.</p> <ul> <li>First hospital in Southern Greece to install the Da Vinci robotic system. Surgeries use just 1 cm punctures.</li> <li>Oncology department shares experience with MD Anderson Cancer Center in the US. Offers IMRT and targeted therapy.</li> <li>Neurosurgery treats Parkinson's and Tourette's with deep brain stimulation. Also performs minimally invasive spinal procedures.</li> <li>Full check-up screens your health in one day. Options include cardiac, urological, gynecologic, and general programs.</li> <li>Holds TEMOS International Healthcare Accreditation and Global Healthcare Accreditation (GHA) for international patient care.</li> </ul>","text_type":"short_description","best_texts":{"techniques":"Robotic surgery, chemotherapy, targeted therapy, IMRT radiotherapy","good_fit_for":"Precision tumor removal with robotic surgery","why_its_ranked":"Uses Da Vinci robotic system for precise tumor removal with minimal tissue damage. Offers combined chemo-radiotherapy and targeted therapy. Part of Greece's largest hospital network."},"agency_settings":[{"setting_name":"is_new","setting_value":"0"},{"setting_name":"kids_only","setting_value":"0"}],"procedure_prices":[{"prices":{"price_from":1300,"price_to":1900,"currency":"USD","id":28499},"diagnostic":{"id":1,"name":"PET/CT","alias":"pet-ct"}}],"reviews":[],"clinic":{"id":399,"alias":"interbalkan-european-medical-center","name":"Interbalkan European Medical Center","short_description":"<p>Interbalkan European Medical Center is a multidisciplinary hospital linked with Massachusetts General Hospital and Harvard University. It specializes in robotic surgery, cardiac surgery, neurosurgery, and oncology. The center belongs to Athens Medical Group, Greece's largest hospital network.</p> <ul> <li>First hospital in Southern Greece to install the Da Vinci robotic system. Surgeries use just 1 cm punctures.</li> <li>Oncology department shares experience with MD Anderson Cancer Center in the US. Offers IMRT and targeted therapy.</li> <li>Neurosurgery treats Parkinson's and Tourette's with deep brain stimulation. Also performs minimally invasive spinal procedures.</li> <li>Full check-up screens your health in one day. Options include cardiac, urological, gynecologic, and general programs.</li> <li>Holds TEMOS International Healthcare Accreditation and Global Healthcare Accreditation (GHA) for international patient care.</li> </ul>","images":[{"base_url":"clinic/5b72eefeed138","title":"Modern exterior of Interbalkan European Medical Center in Thessaloniki, Greece"},{"base_url":"clinic/5b72ee780dc73","title":"Modern glass elevators in marble lobby at Interbalkan European Medical Center Greece"},{"base_url":"clinic/5b72ee79860b3","title":"Reception area at Interbalkan European Medical Center with marble floors and grand piano"},{"base_url":"clinic/5b72ee7a4e485","title":"Patient room at Interbalkan European Medical Center with modern furnishings and city view"}],"flags":[{"name":"is_hide","value":false},{"name":"has_active_agencies","value":false}],"geo":{"country":{"name":"Greece","id":180,"alias":"greece","iso_code":"GR"},"city":{"name":"Thessaloniki","id":384,"alias":"thessaloniki"},"address":" Asklipiou 10, Pilea Chortiatis 555 35"},"rating":{"rating":4.3,"google":3.7,"percent_of_satisfied_clients":87},"statistics":{"number_of_reviews":8,"doctors_number":0,"year_foundation":2000},"accreditations":[{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/5ceb725c9b963.jpeg","name":"TEMOS International Healthcare Accreditation","country_code":"DE"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/5d10bad3836ab.jpeg","name":"Global Healthcare Accreditation Program","country_code":"US"}],"agency_settings":[{"setting_name":"is_new","setting_value":"0"},{"setting_name":"kids_only","setting_value":"0"}]}},{"text":"<p>Ewha Womans University Medical Center specializes in minimally invasive surgeries for women, focusing on aesthetic results with small incisions. Dr. Paik Nam-sun, listed among the world’s top 100 gastric and breast cancer surgeons, leads the Cancer Center for Women. He pioneered breast-conserving surgery in South Korea and developed a unique stomach cancer surgery technique.</p><doctor id=\"1668\"></doctor>","text_type":"mt_wow_description","agency_settings":[{"setting_name":"is_new","setting_value":"0"},{"setting_name":"kids_only","setting_value":"0"}],"procedure_prices":[{"prices":{"price_from":3000,"price_to":8000,"currency":"USD","id":15158},"operation":{"id":708,"name":"Chemotherapy for breast cancer","alias":"chemotherapy-for-breast-cancer"}},{"prices":{"price_from":40,"price_to":90,"currency":"USD","id":15134},"diagnostic":{"id":102,"name":"Consultation with an oncologist","alias":"consultation-of-oncologist"}},{"prices":{"price_from":700,"price_to":1500,"currency":"USD","id":15152},"diagnostic":{"id":1,"name":"PET/CT","alias":"pet-ct"}}],"reviews":[],"clinic":{"id":226,"alias":"ewha-womans-university-medical-center","name":"Ewha Womans University Medical Center","short_description":"<p>Ewha Womans University Medical Center is a JCI-accredited women-only hospital founded in 1887. It specializes in breast, thyroid, and urogenital cancer care, plus joint replacement and robotic surgery. Affiliated with the country's largest women's university.</p> <ul> <li>First in the world to perform robotic gynecological surgery through a single small incision.</li> <li>Only hospital in South Korea that installs artificial bladders made from the patient's own small intestine.</li> <li>Developed the Proxima artificial hip joint that does not require cement for fastening.</li> <li>Recognized as the best hospital for colon cancer treatment by the Ministry of Health and Welfare.</li> <li>Won first place in the national Quality of Services competition for three consecutive years.</li> </ul>","images":[{"base_url":"clinic/5c6183933deff","title":"Ewha Womans University Medical Center main building exterior in Seoul, South Korea"},{"base_url":"clinic/5c61839316cc5","title":"Laparoscopic surgery team at Ewha Womans University Medical Center operating room"},{"base_url":"clinic/5c66b4705680b","title":"Ewha Womans University Medical Center exterior at night, modern hospital in Seoul"},{"base_url":"clinic/5c66b46d88031","title":"Entrance to International Healthcare Center at Ewha Womans University Medical Center"}],"flags":[{"name":"is_hide","value":false},{"name":"has_active_agencies","value":false}],"geo":{"country":{"name":"Republic of Korea","id":36,"alias":"republic-of-korea","iso_code":"KR"},"city":{"name":"Seoul","id":328,"alias":"seoul"},"address":"1071, Anyangcheon-ro, Yangcheon-gu,Seoul 158- 710 Korea"},"rating":{"rating":5,"google":3,"percent_of_satisfied_clients":98},"statistics":{"number_of_reviews":9,"doctors_number":0,"year_foundation":1887},"accreditations":[{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/5cfa0ad8c533a.jpeg","name":"Joint Commission International ","country_code":"US"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/5df76f5a0c887.jpeg","name":"Korean Institute for Healthcare Accreditation","country_code":"KR"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/609cdeda74941.jpeg","name":"World's Best Hospitals 2021 by Newsweek","country_code":"US"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/636103a731801.jpeg","name":"World's Best Hospitals 2022 by Newsweek","country_code":"US"}],"agency_settings":[{"setting_name":"is_new","setting_value":"0"},{"setting_name":"kids_only","setting_value":"0"}]}},{"text":"<p>Estophia Hospital is a private clinic in Istanbul with 87 doctors across 28 departments. Orthopedics, urology, aesthetic medicine, and weight loss surgery are its strongest areas.</p> <ul> <li>98% success rate for breast lifts, tummy tucks, ear surgery, and FUE hair transplants.</li> <li>95% success rate for liposuction procedures.</li> <li>Serves both adults and children in the same facility.</li> <li>Draws patients mainly from Europe, African countries, and the USA.</li> </ul>","text_type":"short_description","agency_settings":[{"setting_name":"is_new","setting_value":"0"},{"setting_name":"kids_only","setting_value":"0"}],"procedure_prices":[{"prices":{"price_from":6000,"price_to":9000,"currency":"USD","id":35985},"operation":{"id":673,"name":"Radiation therapy for colorectal cancer","alias":"radiation-therapy-for-colorectal-cancer"}},{"prices":{"price_from":3000,"price_to":8000,"currency":"USD","id":35963},"operation":{"id":708,"name":"Chemotherapy for breast cancer","alias":"chemotherapy-for-breast-cancer"}},{"prices":{"price_from":250,"price_to":500,"currency":"USD","id":32786},"diagnostic":{"id":96,"name":"CT (computer tomography)","alias":"ct"}},{"prices":{"price_from":650,"price_to":1000,"currency":"USD","id":35934},"diagnostic":{"id":1,"name":"PET/CT","alias":"pet-ct"}}],"reviews":[],"clinic":{"id":1547,"alias":"medical-promise","name":"Estophia Hospital ","short_description":"<p>Estophia Hospital is a private clinic in Istanbul with 87 doctors across 28 departments. Orthopedics, urology, aesthetic medicine, and weight loss surgery are its strongest areas.</p> <ul> <li>98% success rate for breast lifts, tummy tucks, ear surgery, and FUE hair transplants.</li> <li>95% success rate for liposuction procedures.</li> <li>Serves both adults and children in the same facility.</li> <li>Draws patients mainly from Europe, African countries, and the USA.</li> </ul>","images":[{"base_url":"clinic/650d7b3a43c70","title":"Estophia Hospital exterior with city skyline, medical tourism project banner"},{"base_url":"clinic/61af25cbace6b","title":"Modern waiting area with indoor garden at Estophia Hospital, Istanbul"},{"base_url":"clinic/6176d68a53a28","title":"Patient room at Estophia Hospital with modern bed and comfortable seating"},{"base_url":"clinic/61af24e549781","title":"Modern waiting area at Estophia Hospital with stylish seating and glass partitions"}],"flags":[{"name":"is_hide","value":false},{"name":"has_active_agencies","value":false}],"geo":{"country":{"name":"Turkey","id":46,"alias":"turkey","iso_code":"TR"},"city":{"name":"Istanbul","id":107,"alias":"istanbul"},"address":"Merkez, Darülaceze Cd. 14/1, 34381 Şişli/İstanbul, Turkey"},"rating":{"rating":4.4,"google":3.4,"percent_of_satisfied_clients":77},"statistics":{"number_of_reviews":49,"doctors_number":87,"year_foundation":15},"accreditations":[],"agency_settings":[{"setting_name":"is_new","setting_value":"0"},{"setting_name":"kids_only","setting_value":"0"}]}},{"text":"<p>Holistic Bio Spa® specializes in alternative cancer care, including NK cell therapy and exosome treatments for sigmoid adenocarcinoma. Dr. Eduardo Fernandez is one of only 50 certified stem cell therapy experts in Mexico, with pending international certification from the International Society for Stem Cell Research.</p><doctor id=\"8334\"></doctor>","text_type":"mt_wow_description","best_texts":{"techniques":"NK cell therapy, exosome treatments, high-dose vitamin C, ozone therapy, nutritional therapy","good_fit_for":"Complementary cancer care alongside conventional treatments","why_its_ranked":"Specializes in NK cell therapy and exosome treatments for sigmoid adenocarcinoma. Offers personalized nutrition plans and ozone therapy to support conventional treatments."},"agency_settings":[{"setting_name":"is_new","setting_value":"0"},{"setting_name":"kids_only","setting_value":"0"}],"reviews":[],"clinic":{"id":5893,"alias":"holistic-bio-spa","name":"Holistic Bio Spa®","short_description":"<p>Holistic Bio Spa is an integrative medical center in Puerto Vallarta serving 5,000 patients annually. It combines holistic, regenerative, and alternative medicine with conventional care. Core specialties include integrative oncology and peptide therapy.</p> <ul> <li>10-pass hyperbaric ozone therapy, plasmapheresis, and high-dose vitamin C IV treatments available.</li> <li>Uses allogenic NK cell therapy and exosome therapy to target cancer cells.</li> <li>Custom nutritional plans based on DNA testing to strengthen immunity.</li> <li>Offers red light therapy, cryotherapy, PEMF, HOCATT, and TMS for recovery.</li> <li>Treats patients from the USA, Canada, Europe, Australia, and Latin America.</li> </ul>","images":[{"base_url":"clinic/66c261f56178f","title":"Entrance of Holistic Bio Spa clinic with glass doors and plants"},{"base_url":"clinic/66c26207835da","title":"Consultation room at Holistic Bio Spa with exam bed and modern office setup"},{"base_url":"clinic/66c262157b4b5","title":"IV therapy room with recliners and medical monitor at Holistic Bio Spa clinic"},{"base_url":"clinic/66c2621fee9a4","title":"Reception area at Holistic Bio Spa with staff and patient waiting lounge in Mexico"}],"flags":[{"name":"has_active_agencies","value":false},{"name":"is_hide","value":false}],"geo":{"country":{"name":"Mexico","id":40,"alias":"mexico","iso_code":"MX"},"city":{"name":"Puerto Vallarta","id":2531,"alias":"puerto-vallarta"},"address":"Plaza Marina, Local B-10, Marina Vallarta, 48335 Puerto Vallarta, Jal., Puerto Vallarta, Mexico"},"rating":{"rating":0,"google":4.8,"percent_of_satisfied_clients":0},"statistics":{"number_of_reviews":0,"doctors_number":4,"year_foundation":2004},"accreditations":[],"agency_settings":[{"setting_name":"is_new","setting_value":"0"},{"setting_name":"kids_only","setting_value":"0"}]}},{"text":"<p>Hermes Clinics is a doctor-founded healthcare center in Istanbul, Turkey. It specializes in bariatric surgery, plastic surgery, and dental care. A team of physicians founded the clinic in 2019. The medical team has coordinated care for over 30,000 patients. Treatment is provided through licensed partner hospitals and clinics across Istanbul.</p><p>Weight-loss services include gastric sleeve, bypass, and balloon procedures. Dental patients receive full-mouth restorations such as All-on-4 and All-on-6 implants. The clinic holds ISO 9001 certification for its international processes. Oncology care includes stereotactic radiosurgery with Gamma Knife and CyberKnife. Patients also get lifelong aftercare support after weight-loss surgery.</p>","text_type":"short_description","agency_settings":[{"setting_name":"is_new","setting_value":"0"},{"setting_name":"kids_only","setting_value":"0"}],"reviews":[],"clinic":{"id":1169,"alias":"hermes-clinics","name":"Hermes Clinics (Hermes Clinics A.Ş.)","short_description":"<p>Hermes Clinics is a doctor-founded healthcare center in Istanbul, Turkey. It specializes in bariatric surgery, plastic surgery, and dental care. A team of physicians founded the clinic in 2019. The medical team has coordinated care for over 30,000 patients. Treatment is provided through licensed partner hospitals and clinics across Istanbul.</p><p>Weight-loss services include gastric sleeve, bypass, and balloon procedures. Dental patients receive full-mouth restorations such as All-on-4 and All-on-6 implants. The clinic holds ISO 9001 certification for its international processes. 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The hospital is especially known for orthopedics, spine surgery, bone marrow transplantation, and oncology.</p> <ul> <li>First EUROSPINE-certified Surgical Spine Centre of Excellence in Turkey and Asia.</li> <li>One of the largest bone marrow transplant units in the region with 45 beds.</li> <li>JCI-accredited since 2017, also holds ISO 9001 and TÜSKA certificates.</li> <li>Offers PET-CT, 3 Tesla MRI, LINAC Trilogy, and nuclear medicine therapies.</li> <li>Provides airport transfers, interpreters, and accommodation for international patients.</li> </ul>","images":[{"base_url":"clinic/6149da44dd434","title":"Modern exterior of Emsey Hospital in Istanbul, Turkey, multi-story medical facility"},{"base_url":"clinic/616d78db4d7c0","title":"Modern reception area at Emsey Hospital with spacious medical facility interior"},{"base_url":"clinic/616d7a18a32f4","title":"Patient room at Emsey Hospital with hospital bed, sofa, and modern furnishings"},{"base_url":"clinic/616fd327b31e4","title":"Multidisciplinary tumor board meeting at Emsey Hospital with doctors reviewing scans"}],"flags":[{"name":"is_hide","value":false},{"name":"has_active_agencies","value":false}],"geo":{"country":{"name":"Turkey","id":46,"alias":"turkey","iso_code":"TR"},"city":{"name":"Istanbul","id":107,"alias":"istanbul"},"address":"Çamlık, Selçuklu Cd. 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Dr. Pastrana combines surgical expertise with academic teaching at Universidad Anahuac.</p><ul><li>Trained at Centro Medico Nacional 20 de Noviembre</li><li>Board certified by Conacem until 2030</li><li>Active member of the Mexican Oncology Society</li><li>Specializes in minimally invasive techniques</li></ul>","doctor":{"id":10452,"alias":"brenda-pastrana","name":"Brenda Pastrana","clinic_id":6904,"photo":"doctor/6890e1455c4b6","first_year_working":2020,"created_at":"2025-08-04T16:35:15.050+00:00","short_description":"<p>Dr. Brenda Pastrana is a surgical oncologist at the JCI-accredited Galenia Hospital in Cancún. She specializes in breast, thyroid, and digestive system cancers. Dr. Pastrana is board-certified by CONACEM. She holds a medical degree from the Universidad Autónoma de México.</p><ul><li>Performs mastectomies, liver resections, and complex colon cancer surgeries.</li><li>Treats patients at a facility holding Accreditation Canada Diamond Status.</li><li>Serves as a university teacher at Universidad Anáhuac.</li><li>Member of the Mexican Society of Oncology (SMEO).</li></ul>","specialities":[{"id":"sur.007","name":"Surgical oncologist","illness_kind_id":33},{"id":"sur.010","name":"General surgeon","illness_kind_id":33},{"id":"sur.021","name":"Breast surgeon","illness_kind_id":33}],"statistics":{"review_count":1,"review_score":5}},"clinic":{"id":6904,"alias":"galenia-hospital","name":"Galenia Hospital","short_description":"<p>Galenia Hospital is a JCI-accredited private medical center in Cancún, Mexico. Its core specialties are oncology, surgery, and mammology. The hospital treats around 10,000 patients each year, many coming from the US and Canada.</p> <ul> <li>Holds Accreditation Canada Diamond Status for quality and safety.</li> <li>Offers breast-conserving surgery alongside mastectomy procedures.</li> <li>200 physicians across 10 departments provide adult-only care.</li> <li>Serves a diverse international patient base from Latin America, Australia, and Europe.</li> </ul>","images":[{"base_url":"clinic/68aa61a7ecb82","title":"Modern facade of Galenia Hospital in Cancun, Mexico"},{"base_url":"clinic/68aa62231d8c7","title":"Galenia Hospital modern clinic exterior in Cancun, Mexico"},{"base_url":"clinic/68aa622a9d841","title":"Galenia Hospital exterior illuminated at night in Mexico"},{"base_url":"clinic/68aa6231a17e9","title":"Modern exterior of Galenia Hospital in Cancun, Mexico"}],"flags":[{"name":"has_active_agencies","value":false},{"name":"is_hide","value":false}],"geo":{"country":{"name":"Mexico","id":40,"alias":"mexico","iso_code":"MX"},"city":{"name":"Cancún","id":454,"alias":"cancun"},"address":"Cancun 28, Mercado, 77516 Soledad de Graciano Sánchez, Q.R., Mexico"},"rating":{"rating":4,"google":3.2,"percent_of_satisfied_clients":98},"statistics":{"number_of_reviews":1,"doctors_number":200,"year_foundation":2006},"accreditations":[{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/5cfa0ad8c533a.jpeg","name":"Joint Commission International ","country_code":"US"},{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/6194fa5077fec.jpeg","name":"Accreditation Canada Diamond Status Level ","country_code":"CA"}]},"procedure_prices":[{"prices":{"price_from":25000,"price_to":35000,"currency":"USD","id":52174},"operation":{"id":448,"name":"Colectomy (large bowel resection)","alias":"colectomy-large-bowel-resection"}}]},{"card_text":"<p>Head of Teaching at Puerto Vallarta Regional Hospital with specialized training in minimally invasive procedures.</p><ul><li>Biomagnet certified by the Higher Institute of Biomagnetism</li><li>Experience in clinical records management</li><li>Assisted in dermatological procedures including laser treatments</li><li>Training in professional development for medical educators</li></ul>","doctor":{"id":8330,"alias":"eslie-perez","name":"Eslie Perez","clinic_id":5893,"photo":"doctor/66bf92e90ec43","first_year_working":2014,"created_at":"2024-08-16T17:56:55.728+00:00","short_description":"<p>Dr. Eslie Perez is a general practitioner at Holistic Bio Spa in Puerto Vallarta. She is certified in biomagnetism by the Higher Institute of Biomagnetism. Dr. Perez served as the Head of Teaching at the Puerto Vallarta Regional Hospital. She specializes in integrating dermatological procedures with regenerative therapies.</p><ul><li>Performs stem cell rejuvenation and intravenous vitamin C therapies.</li><li>Expert in minimally invasive facial rejuvenation using IPL and fractional laser.</li><li>Provides ozone therapy and mesenchymal stem cell treatments.</li><li>Clinical experience in treating psoriasis and vitiligo with UV light phototherapy.</li></ul>","specialities":[{"id":"gnp.001","name":"General practitioner","illness_kind_id":32}],"statistics":{"review_count":0,"review_score":0}},"clinic":{"id":5893,"alias":"holistic-bio-spa","name":"Holistic Bio Spa®","short_description":"<p>Holistic Bio Spa is an integrative medical center in Puerto Vallarta serving 5,000 patients annually. It combines holistic, regenerative, and alternative medicine with conventional care. Core specialties include integrative oncology and peptide therapy.</p> <ul> <li>10-pass hyperbaric ozone therapy, plasmapheresis, and high-dose vitamin C IV treatments available.</li> <li>Uses allogenic NK cell therapy and exosome therapy to target cancer cells.</li> <li>Custom nutritional plans based on DNA testing to strengthen immunity.</li> <li>Offers red light therapy, cryotherapy, PEMF, HOCATT, and TMS for recovery.</li> <li>Treats patients from the USA, Canada, Europe, Australia, and Latin America.</li> </ul>","images":[{"base_url":"clinic/66c261f56178f","title":"Entrance of Holistic Bio Spa clinic with glass doors and plants"},{"base_url":"clinic/66c26207835da","title":"Consultation room at Holistic Bio Spa with exam bed and modern office setup"},{"base_url":"clinic/66c262157b4b5","title":"IV therapy room with recliners and medical monitor at Holistic Bio Spa clinic"},{"base_url":"clinic/66c2621fee9a4","title":"Reception area at Holistic Bio Spa with staff and patient waiting lounge in Mexico"}],"flags":[{"name":"has_active_agencies","value":false},{"name":"is_hide","value":false}],"geo":{"country":{"name":"Mexico","id":40,"alias":"mexico","iso_code":"MX"},"city":{"name":"Puerto Vallarta","id":2531,"alias":"puerto-vallarta"},"address":"Plaza Marina, Local B-10, Marina Vallarta, 48335 Puerto Vallarta, Jal., Puerto Vallarta, Mexico"},"rating":{"rating":0,"google":4.8,"percent_of_satisfied_clients":0},"statistics":{"number_of_reviews":0,"doctors_number":4,"year_foundation":2004},"accreditations":[]},"images":[{"image_url":"https://s3.eu-central-1.amazonaws.com/bookimed/operations_images/66e2b2e7d9496.jpeg","seo_alt":"Before and after stem cell therapy for knee at Holistic Bio Spa®, improved mobility result"}]},{"doctor":{"id":5637,"alias":"dr-saban-secmeler","name":"Dr Saban Secmeler","clinic_id":1169,"photo":"doctor/642adf23ddd0f","first_year_working":2012,"created_at":"1970-01-20T10:48:51.234+00:00","short_description":"Dr. Saban Secmeler is a medical professional known for his contribution to cancer research, particularly a significant study on the impact of body mass index on the recurrence and survival rates in early-stage colorectal cancer.","specialities":[{"id":"onc.001","name":"Clinical oncologist","illness_kind_id":10}],"statistics":{"review_count":0,"review_score":0,"operations_performed_count":0,"awards_count":0}},"clinic":{"id":1169,"alias":"hermes-clinics","name":"Hermes Clinics (Hermes Clinics A.Ş.)","short_description":"<p>Hermes Clinics is a doctor-founded healthcare center in Istanbul, Turkey. It specializes in bariatric surgery, plastic surgery, and dental care. A team of physicians founded the clinic in 2019. The medical team has coordinated care for over 30,000 patients. Treatment is provided through licensed partner hospitals and clinics across Istanbul.</p><p>Weight-loss services include gastric sleeve, bypass, and balloon procedures. Dental patients receive full-mouth restorations such as All-on-4 and All-on-6 implants. The clinic holds ISO 9001 certification for its international processes. Oncology care includes stereotactic radiosurgery with Gamma Knife and CyberKnife. Patients also get lifelong aftercare support after weight-loss surgery.</p>","images":[{"base_url":"clinic/6a78a873f2c62","title":"Modern waiting area at Hermes Clinics with comfortable seating and decor"},{"base_url":"clinic/6a78a875d529d","title":"Patient room at Hermes Clinics with hospital bed, TV, and modern furnishings"},{"base_url":"clinic/6a78a87791497","title":"Modern clinic lobby at Hermes Clinics with grand piano and stylish decor"},{"base_url":"clinic/6a78a87971c3a","title":"Modern glass facade of Medical Park clinic in Istanbul, Turkey"}],"flags":[{"name":"is_hide","value":false},{"name":"has_active_agencies","value":false}],"geo":{"country":{"name":"Turkey","id":46,"alias":"turkey","iso_code":"TR"},"city":{"name":"Ankara","id":386,"alias":"ankara"},"address":"FOLKART TIME, Kazım Dirik Mah Ankara Cad. 296 Sok. No:8 1.Blok K:3 Daire:306, 35080 Bornova/İzmir, Türkiye"},"rating":{"rating":4.5,"google":4.3,"percent_of_satisfied_clients":85},"statistics":{"number_of_reviews":20,"doctors_number":1,"year_foundation":2019},"accreditations":[{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/5cfa0ad8c533a.jpeg","name":"Joint Commission International ","country_code":"US"}]}},{"card_text":"<p>Abdullah Sakin leads the Medical Oncology Department at Medipol Bahçelievler Hospital, specializing in advanced treatment protocols.</p><ul><li>Head of Medical Oncology at Yüzüncü Yıl University Faculty of Medicine</li><li>Trained at Istanbul Okmeydanı Training and Research Hospital in Medical Oncology</li><li>Specialist in Internal Medicine with extensive clinical experience</li></ul>","doctor":{"id":6837,"alias":"abdullah-sakin","name":"Abdullah Sakin","clinic_id":4904,"photo":"doctor/658011d19c68b","first_year_working":2007,"created_at":"2023-12-14T11:22:18.910+00:00","short_description":"<p>Dr. Abdullah Sakin is a medical oncologist at Medipol Bahçelievler University Hospital in Istanbul. He specializes in treating complex cancers, including lung, breast, and gastrointestinal malignancies. Dr. Sakin previously served as the Head of the Medical Oncology Department at Yüzüncü Yıl University. He also held a leadership role at Prof. Dr. Cemil Taşçıoğlu City Hospital.</p><ul><li>Provides immunotherapy, biological therapy, and hormone treatments for various cancer types.</li><li>Treats rare and difficult conditions like thymoma, chordoma, and Ewing's sarcoma.</li><li>Performs PET-CT scans and comprehensive oncological check-ups for men and women.</li><li>Uses JCI-accredited facilities with systems like TrueBeam STx and Halcyon for treatment.</li></ul>","specialities":[{"id":"onc.006","name":"Oncologist/mammologist","illness_kind_id":10}],"statistics":{"review_count":0,"review_score":0}},"clinic":{"id":4904,"alias":"medipol-bahcelievler","name":"Medipol Bahçelievler Univesity Hospital ","short_description":"<p>Medipol Bahçelievler University Hospital is a JCI-accredited facility and the second-largest hospital in the Medipol Health Group. It treats 600,000 patients each year with a focus on cardiology, oncology, and heart surgery.</p> <ul> <li>Opened in 2022 with 14 operating rooms and a 52-incubator neonatal ICU.</li> <li>PET-CT completes a full-body tumor scan in 5 minutes, with 4x higher contrast than standard PET-CT.</li> <li>Radiation oncology uses TrueBeam STx and Halcyon systems for stereotactic treatments in 1–5 days.</li> <li>Nuclear medicine department offers Lu-177 PSMA/DOTA and Y-90 microsphere therapies.</li> <li>Cardiology and cardiovascular surgery perform TAVI, coronary bypass, and carotid artery procedures.</li> </ul>","images":[{"base_url":"clinic/6576f6bea30c7","title":"Modern exterior of Medipol Bahçelievler Hospital in Istanbul, Turkey"},{"base_url":"clinic/6576f6dd3a0bd","title":"Modern exterior of Medipol Bahçelievler Hospital in Istanbul, Turkey"},{"base_url":"clinic/6576f7115b376","title":"Reception area at Medipol Bahçelievler Hospital, modern design with seating"},{"base_url":"clinic/6576f74a65d1c","title":"Consultation room at Medipol Bahçelievler Hospital with modern medical equipment"}],"flags":[{"name":"is_hide","value":false},{"name":"has_active_agencies","value":false}],"geo":{"country":{"name":"Turkey","id":46,"alias":"turkey","iso_code":"TR"},"city":{"name":"Istanbul","id":107,"alias":"istanbul"},"address":"Çobançeşme, Fatih Cd. No:1/8, 34196 Bahçelievler/Istanbul, Turkey"},"rating":{"rating":4.5,"google":3.4,"percent_of_satisfied_clients":98},"statistics":{"number_of_reviews":2,"doctors_number":149,"year_foundation":2022},"accreditations":[{"logo":"https://s3.eu-central-1.amazonaws.com/bookimed/accreditations/5cfa0ad8c533a.jpeg","name":"Joint Commission International ","country_code":"US"}]},"procedure_prices":[{"prices":{"price_from":4000,"price_to":7000,"currency":"USD","id":40790},"operation":{"id":673,"name":"Radiation therapy for colorectal cancer","alias":"radiation-therapy-for-colorectal-cancer"}},{"prices":{"price_from":8000,"price_to":14000,"currency":"USD","id":40784},"operation":{"id":448,"name":"Colectomy (large bowel resection)","alias":"colectomy-large-bowel-resection"}}]},{"card_text":"<p>Assoc. Prof. Nail Paksoy specializes in medical oncology at Medipol Bahcelievler Hospital, with a focus on gastrointestinal cancers.</p><ul><li>ESMO Board Certified in Medical Oncology</li><li>Participated in international clinical trials for colorectal cancer treatments</li><li>Published research on FLOT regimen for metastatic gastric cancer</li></ul>","doctor":{"id":6840,"alias":"nail-paksoy","name":"Nail Paksoy","clinic_id":4904,"photo":"doctor/6580116849dc1","first_year_working":2011,"created_at":"2023-12-14T13:40:55.728+00:00","short_description":"<p>Dr. Nail Paksoy is an associate professor of medical oncology at Medipol Bahçelievler Hospital. He is board-certified by the European Society for Medical Oncology (ESMO). Dr. Paksoy specializes in lung, breast, and gastrointestinal cancers. He uses modern immunotherapy and targeted therapy protocols. His clinic is JCI-accredited for high safety standards.</p><ul><li>Served as a subinvestigator in over 8 international clinical trials for Roche and Pfizer.</li><li>Authored over 40 research articles in journals indexed by SCI and SSCI.</li><li>Completed dual fellowships in allergy-immunology and medical oncology.</li><li>Treats complex sarcomas and renal cell carcinomas with systemic therapies.</li></ul>","specialities":[{"id":"onc.006","name":"Oncologist/mammologist","illness_kind_id":10}],"statistics":{"review_count":0,"review_score":0},"certificates":[{"url":"https://s3.eu-central-1.amazonaws.com/bookimed/doctor/certificate/659ed4375d1b7.jpeg","name":"ESMO Board Certification in Medical Oncology"}]},"clinic":{"id":4904,"alias":"medipol-bahcelievler","name":"Medipol Bahçelievler Univesity Hospital ","short_description":"<p>Medipol Bahçelievler University Hospital is a JCI-accredited facility and the second-largest hospital in the Medipol Health Group. It treats 600,000 patients each year with a focus on cardiology, oncology, and heart surgery.</p> <ul> <li>Opened in 2022 with 14 operating rooms and a 52-incubator neonatal ICU.</li> <li>PET-CT completes a full-body tumor scan in 5 minutes, with 4x higher contrast than standard PET-CT.</li> <li>Radiation oncology uses TrueBeam STx and Halcyon systems for stereotactic treatments in 1–5 days.</li> <li>Nuclear medicine department offers Lu-177 PSMA/DOTA and Y-90 microsphere therapies.</li> <li>Cardiology and cardiovascular surgery perform TAVI, coronary bypass, and carotid artery procedures.</li> </ul>","images":[{"base_url":"clinic/6576f6bea30c7","title":"Modern exterior of Medipol Bahçelievler Hospital in Istanbul, Turkey"},{"base_url":"clinic/6576f6dd3a0bd","title":"Modern exterior of Medipol Bahçelievler Hospital in Istanbul, Turkey"},{"base_url":"clinic/6576f7115b376","title":"Reception area at Medipol Bahçelievler Hospital, modern design with seating"},{"base_url":"clinic/6576f74a65d1c","title":"Consultation room at Medipol Bahçelievler Hospital with modern medical equipment"}],"flags":[{"name":"is_hide","value":false},{"name":"has_active_agencies","value":false}],"geo":{"country":{"name":"Turkey","id":46,"alias":"turkey","iso_code":"TR"},"city":{"name":"Istanbul","id":107,"alias":"istanbul"},"address":"Çobançeşme, Fatih Cd. 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He is recognized as one of the world's top 100 gastric and breast cancer surgeons. He performed the first breast-conserving surgery in South Korea. Dr. Paik also invented a proprietary stomach cancer technique to reduce reflux disease risk.</p> <ul> <li>Director of the Cancer Center for Women at Ewha Womans University Medical Center.</li> <li>Former President of Konkuk University Hospital.</li> <li>Served as the Director of the Korea Cancer Center Hospital.</li> <li>Former President of the Korean Society of Cancer Prevention.</li> </ul>","specialities":[{"id":"sur.007","name":"Surgical oncologist","illness_kind_id":33}],"statistics":{"review_count":0,"review_score":0,"operations_performed_count":0,"awards_count":0},"certificates":[{"url":"https://s3.eu-central-1.amazonaws.com/bookimed/doctor/certificate/659c70eb842da.jpeg","name":"The Korean Cancer Association"}]},"clinic":{"id":226,"alias":"ewha-womans-university-medical-center","name":"Ewha Womans University Medical Center","short_description":"<p>Ewha Womans University Medical Center is a JCI-accredited women-only hospital founded in 1887. It specializes in breast, thyroid, and urogenital cancer care, plus joint replacement and robotic surgery. 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