The Demarest Clinic specializes in regenerative medicine, backed by AABB-certified cellular therapies. Dr. Tatiana Zhelninova-Bosch, MD, PhD, brings _doctor_9127_years_ in cardiology and family medicine, with leadership roles at Hadassah Medical Center and pioneering stem cell therapy research. The clinic focuses on advanced treatments including Vagus nerve stimulation with a commitment to continuous protocol updates through global research networks.
The Demarest Clinic is the first clinic in Thailand sanctioned by the Health Ministry for allogeneic stem cell therapy. It specializes in regenerative medicine and cellular therapies.
Hisar Hospital Intercontinental, a JCI-accredited facility, offers Deep Brain Stimulation (DBS) surgery with prices typically around $9,900–$12,100. The clinic's neurosurgical team leverages advanced functional neurosurgery techniques, though no specific DBS-experienced doctors are listed in the provided data.
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Liv Bona Dea Hospital offers comprehensive DBS surgery for Parkinson's disease, typically costing around $22,000 USD. The package includes neurosurgeon consultation, pre-op analyses, 5-day hospital stay, and interpreter services. The JCI-accredited hospital follows international safety standards and provides airport transfers. Prof. Mete Karatay, a specialized neurosurgeon, oversees the treatment process.
","text_type":"mt_wow_description","best_texts":{"techniques":"Deep brain stimulation (DBS) surgery","good_fit_for":"Parkinson's disease patients","why_its_ranked":"Offers DBS surgery with JCI accreditation and free interpreter services. Estimated price for DBS operation is 22,000 USD."},"additional_data":{"advertising_id":"3325:illness_kind:7"},"agency_settings":[{"setting_name":"is_new","setting_value":"0"},{"setting_name":"kids_only","setting_value":"0"}],"procedure_prices":[{"prices":{"price_from":22000,"price_to":22000,"currency":"USD","id":37343},"operation":{"id":146,"name":"Deep brain stimulation (DBS) surgery","alias":"deep-brain-stimulation"}},{"prices":{"price_from":370,"price_to":370,"currency":"USD","id":37337},"diagnostic":{"id":6,"name":"MRI of one area","alias":"mri-one-department"}},{"prices":{"price_from":150,"price_to":750,"currency":"USD","id":37352},"diagnostic":{"id":124,"name":"EEG (Electroencephalography)","alias":"eeg-electroencephalography"}}],"reviews":[],"clinic":{"id":3325,"alias":"liv-bona-dea-hospital-baku","name":"Liv Bona Dea Hospital Baku","short_description":"Liv Bona Dea Hospital Baku is a JCI-accredited hospital with 100% compliance. It is part of the Turkish Liv Hospital brand. The hospital specializes in heart surgery, plastic surgery, transplantology, and medical check-ups.
Dr. Tatiana Zhelninova-Bosch is a cardiologist and regenerative medicine specialist at The Demarest Clinic in Phuket. She is a recognized leader in stem cell therapy and clinical trial management. Dr. Zhelninova-Bosch previously served as the Chief Physician and Medical Director of Hadassah Medical Moscow. She treats complex conditions like atherosclerosis, heart failure, and pulmonary hypertension.
The Demarest Clinic is the first clinic in Thailand sanctioned by the Health Ministry for allogeneic stem cell therapy. It specializes in regenerative medicine and cellular therapies.
This surgery cuts brain nerve fibers to stop severe epilepsy without removing brain tissue.
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"},"408":{"operation":{"name":"Surgical treatment of epilepsy","alias":"surgical-treatment-of-epilepsy","use_for_listing":true},"country_price":{"US":{"amount":85000,"max_amount":140000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"TR":{"amount":9600,"max_amount":14500,"currency":"USD","clinic_count":4,"price_kind":"from_range","price_source":"tariff","scope":"country"},"TH":{"amount":14000,"max_amount":23000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"AT":{"amount":24000,"max_amount":39000,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"ES":{"amount":75900,"max_amount":0,"currency":"USD","clinic_count":1,"price_kind":"from","price_source":"offer","scope":"country"}},"available_clinics":{"US":false,"TR":true,"TH":false,"AT":false,"ES":true},"description":"Brain tissue removal causing seizures, improving patients\" quality of life and reducing medicines.
"},"410":{"operation":{"name":"Medication treatment for epilepsy","alias":"medication-for-epilepsy","use_for_listing":true},"country_price":{"US":{"amount":2500,"max_amount":5200,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"TR":{"amount":1300,"max_amount":1800,"currency":"USD","clinic_count":4,"price_kind":"from_range","price_source":"tariff","scope":"country"},"TH":{"amount":900,"max_amount":1600,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"AT":{"amount":1200,"max_amount":3500,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"},"ES":{"amount":900,"max_amount":2300,"currency":"USD","clinic_count":0,"price_kind":"estimate","price_source":"parsed","scope":"country"}},"available_clinics":{"US":false,"TR":true,"TH":false,"AT":false,"ES":false},"description":"This therapy uses drugs to control seizures, helping patients lead normal, active lives.
"}}},"operationIndicators":{"details":{"anesthesia":"local","days_in_clinic":1,"days_in_country":2,"rehabilitation_days":1,"satisfied_percent":78,"treatment_duration_hours":1},"illness_kind_details":{"requests_processed":25926}},"responsibleDoctor":{"id":270,"alias":"antonio-russi","name":"Antonio Russi","photo":"doctor/5acf6037229bd","advisory_text":"Prof. Antonio Russi is recognized as the best epileptologist in Spain. The Doctor specializes in non-surgical therapy of severe and rare epilepsy stages. He helps children and adults to get rid of seizures for good.\nProf. Antonio Russi is an apparent expert in epilepsy diagnosing and choosing the most appropriate drugs in each particular case. Medication therapy helps patients in 70% of cases.\n\nProf. Russi is included in the ranking of Top 100 Spanish doctors by the Forbes magazine, the world's authoritative edition.","linkedin":"","specialities":[{"id":"nrl.001","name":"Neurologist","illness_kind_id":7},{"id":"nrl.003","name":"Epileptologist","illness_kind_id":7}]},"direction":{"id":7,"name":"Neurology","alias":"neurology"},"illness_kind":{"id":7,"name":{"en":"Neurology"}},"parsed_details":{"procedure_type":"surgery","fields":{"anesthesia":["general"],"back_to_work_days":{"min":7,"max":14,"unit":"days","qualifier":"Typical for office-type work after implantation of the pulse generator and lead; depends on wound comfort and neck/chest incision healing."},"complication_rate_pct":{"min":5,"max":15,"unit":"percent","qualifier":"Surgical or perioperative complications such as infection, vocal cord paresis, hematoma; serious ones under 3%. Stimulation side effects excluded."},"contraindications":["Prior bilateral or left cervical vagotomy (device contraindication)","Active systemic or implant-site infection","Inability to tolerate general anesthesia or surgery"],"days_in_clinic":{"min":2,"max":5,"unit":"nights","qualifier":"Overnight admission after surgery; flight home after surgeon clearance and neck swelling settles."},"diagnostic_duration_minutes":null,"diagnostic_preparation":null,"diagnostic_referral_needed":null,"diagnostic_result_time_hours":null,"exercise_resume_weeks":{"min":2,"max":4,"unit":"weeks","qualifier":"Light activity earlier; strenuous upper-body and vigorous neck exercise wait until incisions heal."},"final_result_months":{"min":6,"max":24,"unit":"months","qualifier":"Benefit builds gradually with titration; seizure reduction often improves over 1–2 years. Response varies; some do not respond."},"fly_home_after_days":{"min":3,"max":5,"unit":"days","qualifier":"After surgeon clearance; depends on neck swelling, voice or swallowing symptoms, and flight length. Wound check can be done locally."},"follow_up_visits":[{"purpose":"wound_check","requirement":"routine","after":{"min":7,"max":14,"unit":"days","qualifier":"Incision check, often with suture removal if non-absorbable sutures used."}},{"purpose":"assessment","requirement":"routine","after":{"min":14,"max":28,"unit":"days","qualifier":"Device activation and start of stimulation titration, commonly 2-4 weeks after implantation; subsequent adjustment visits follow."}}],"indications":["Drug-resistant epilepsy, adjunctive, when resective surgery unsuitable or ineffective","Treatment-resistant depression after multiple failed antidepressant trials"],"main_risks":["Surgical site infection, hematoma or pain at incision","Vocal cord paresis; vagus or cervical nerve injury, facial weakness","Bradycardia or asystole during intraoperative lead testing (rare)","Swallowing difficulty, aspiration, worsening sleep apnea","Lead fracture or device malfunction requiring reoperation","Anesthesia-related risks"],"pain":"Moderate incisional discomfort in the neck and chest/axilla for several days, usually managed with oral analgesics. Stimulation-related throat tingling or voice changes may occur after activation.","preparation":["Specialist evaluation confirming drug-resistant epilepsy or treatment-resistant depression and suitability","Preoperative assessment for general anesthesia, including medical history review","Fasting before general anesthesia as instructed","Review other implants and planned imaging; device affects MRI","Counseling on expected benefits, delayed onset, and battery replacement"],"recovery_timeline":[{"phase":"Day of surgery to first week","description":"Overnight admission; incisional soreness, neck swelling and transient hoarseness or swallowing discomfort are common.","restrictions":["Keep incisions dry and follow wound care instructions","Avoid heavy lifting and vigorous neck movement"]},{"phase":"Weeks 2-4","description":"Incisions heal; stimulation is typically switched on and gradually increased at clinic visits.","restrictions":["Avoid strenuous upper-body exercise until cleared"]},{"phase":"Months 1-12","description":"Stimulation settings are optimized stepwise and response is monitored.","restrictions":[]}],"rehabilitation_days":{"min":7,"max":14,"unit":"days","qualifier":"Ordinary functional recovery from implantation surgery; no formal rehabilitation program is usually required."},"result_longevity":"Therapy is ongoing while the device is active. Generator battery typically lasts several years depending on model and settings, and replacement surgery is needed when depleted; individual response varies.","revision_rate_pct":{"min":5,"max":15,"unit":"percent","qualifier":"Reoperation for lead or device malfunction, infection or repositioning, excluding planned battery replacement; within several years."},"scars":"Two small incisions: one in the left neck (often along a skin crease) and one in the upper chest or axilla for the generator; usually fade to fine scars.","sessions_or_stages":{"sessions":{"min":1,"max":1,"unit":"visits","qualifier":"One surgical implantation procedure; later programming visits are follow-up care."},"stages":[{"code":"implantation","label":"Implantation of lead on left vagus nerve and pulse generator","after":{"min":0,"max":0,"unit":"days","qualifier":"Day of surgery"}}],"qualifier":"Standalone initial implantation; battery replacement and stimulation titration are separate."},"success":{"metric":"Patients with at least 50% seizure reduction","value":50,"unit":"percent of patients","horizon":"1-2 years after implantation","population":"Adults with drug-resistant epilepsy not suitable for resective surgery","evidence_status":"limited"},"techniques":[{"name":"Implantable cervical vagus nerve stimulator (lead on left cervical vagus nerve with chest-wall pulse generator)","suits_whom":"Adults with drug-resistant epilepsy or selected treatment-resistant depression who meet device criteria.","recovery":"Usually brief hospital stay; return to light activity within about 1–2 weeks."}],"treatment_conditions":["inpatient"],"treatment_duration_hours":{"min":1,"max":2,"unit":"hours","qualifier":"Operative time for a single primary implantation of lead and generator under general anesthesia."},"initial_assessment_documents":["Neurologist report with epilepsy or depression diagnosis","List of failed antiseizure or antidepressant drugs","Brain MRI report","EEG report","ECG report or cardiac history summary"],"travel_trips":{"min":1,"max":2,"one_trip_possible":true,"qualifier":"Implant surgery with 2-5 night stay. Activation 2-4 weeks later; a local neurologist avoids a second trip."},"clinic_checks":{"status":"ok","items":[{"id":"C1","text":"Check the surgeon’s credentials and experience, including how many of these surgeries they have performed","scope":"procedure","source":{"url":"https://mcpress.mayoclinic.org/living-well/facing-a-diagnosis-and-navigating-the-journey-ahead/","host":"mcpress.mayoclinic.org","quote":"Who is performing the surgery? What are their credentials and experience? How many of these surgeries have they done?","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":403}},{"id":"C2","text":"Check that the clinic provides follow-up visits to ensure the pulse generator works and has not moved","scope":"procedure","source":{"url":"https://www.mayoclinic.org/tests-procedures/vagus-nerve-stimulation/about/pac-20384565","host":"mayoclinic.org","quote":"You need to make follow-up visits to your healthcare professional to make sure that the pulse generator is working and hasn't moved out of place.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":403}},{"id":"C3","text":"Check when the clinic will turn on and program the pulse generator after implantation","scope":"procedure","source":{"url":"https://www.mayoclinic.org/tests-procedures/vagus-nerve-stimulation/about/pac-20384565","host":"mayoclinic.org","quote":"If you had the device implanted to treat epilepsy or depression, your healthcare team turns on the pulse generator during a medical visit a few weeks after surgery.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":403}},{"id":"C4","text":"Confirm the surgeon is trained and experienced in the exact procedure you are considering, not just in surgery generally","scope":"treatment_abroad","source":{"url":"https://www.isaps.org/discover/patients-home/considering-your-procedure-abroad/finding-a-surgeon-abroad/","host":"isaps.org","quote":"Verify that the surgeon is trained and experienced in performing the procedure you are considering.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"C5","text":"Ask for certification information and the name of the body that certified the surgical setting","scope":"treatment_abroad","source":{"url":"https://www.isaps.org/discover/patients-home/considering-your-procedure-abroad/finding-a-surgeon-abroad/","host":"isaps.org","quote":"Ask for certification information and the name of the certifying body when assessing a surgical setting.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-13","next_check_at":"2027-11-13","version":1},"red_flags":{"status":"ok","items":[{"id":"F1","text":"An advert or information that guarantees complete success should raise concerns","scope":"treatment_abroad","source":{"url":"https://travelaware.campaign.gov.uk/surgery-abroad-cut-out-the-risk/","host":"travelaware.campaign.gov.uk","quote":"Any advert or information that guarantees complete success should raise concerns.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"F2","text":"Forceful persuasion or cheap, time-limited offers pushing you into a quick decision","scope":"treatment_abroad","source":{"url":"https://travelaware.campaign.gov.uk/surgery-abroad-cut-out-the-risk/","host":"travelaware.campaign.gov.uk","quote":"Don’t be pressured into quick decisions either through forceful persuasion or cheap, time limited offers.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"F3","text":"A price that sounds too good to be true probably is","scope":"treatment_abroad","source":{"url":"https://www.plasticsurgery.org/news/articles/will-economic-uncertainty-drive-more-patients-overseas-for-plastic-surgery-what-to-consider-and-how-to-stretch-your-dollar-back-home","host":"plasticsurgery.org","quote":"If the price sounds too good to be true, it probably is.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-13","next_check_at":"2027-11-13","version":1},"warning_signs":{"status":"ok","items":[{"id":"W1","text":"Vocal cord paralysis","urgency":"contact_clinic","general":false,"source":{"url":"https://my.clevelandclinic.org/health/treatments/17598-vagus-nerve-stimulation","host":"my.clevelandclinic.org","quote":"Vocal cord paralysis .","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},{"id":"W2","text":"Heart stops beating (cardiac arrest)","urgency":"emergency","general":false,"source":{"url":"https://my.clevelandclinic.org/health/treatments/17598-vagus-nerve-stimulation","host":"my.clevelandclinic.org","quote":"Your heart may stop beating ( cardiac arrest ).","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},{"id":"W3","text":"Muscle weakness in the lower face","urgency":"contact_clinic","general":false,"source":{"url":"https://my.clevelandclinic.org/health/treatments/17598-vagus-nerve-stimulation","host":"my.clevelandclinic.org","quote":"Muscle weakness in your lower face (facial muscle paresis).","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},{"id":"W4","text":"Shortness of breath or trouble breathing","urgency":"contact_clinic","general":false,"source":{"url":"https://my.clevelandclinic.org/health/treatments/17598-vagus-nerve-stimulation","host":"my.clevelandclinic.org","quote":"Coughing. Hoarseness. Change in voice. Neck pain or throat pain or tickling. Shortness of breath/trouble breathing ( dyspnea ).","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}}],"checked_at":"2026-11-13","next_check_at":"2027-11-13","version":1},"take_home":{"status":"ok","items":[{"id":"T1","text":"Ask for written details of the procedure before you leave the hospital","document":"written procedure details","source":{"url":"https://rcseng.ac.uk/patient-care/cosmetic-surgery/after-surgery/","host":"rcseng.ac.uk","quote":"After your surgery, before you leave the hospital, ask for written information about the procedure you've had.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T2","text":"Home doctor needs the clinic's follow-up recommendations in a written discharge summary","document":"discharge summary","source":{"url":"https://sbuhb.nhs.wales/about-us/individual-patient-commissioning/ipc-folder/advice-on-accessing-treatment-abroad","host":"sbuhb.nhs.wales","quote":"When you have treatment abroad, you must ask the treatment provider for their follow-up recommendations documented within a written discharge summary in English.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T3","text":"Ask for copies of all prescriptions before you leave","document":"prescription copies","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"Remember to ask for copies of all your treatment records, including prescriptions, scans and x-rays before you leave.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T4","text":"Home doctor needs the dates for required blood tests and follow-up appointments","document":"written aftercare plan","source":{"url":"https://sbuhb.nhs.wales/about-us/individual-patient-commissioning/ipc-folder/advice-on-accessing-treatment-abroad","host":"sbuhb.nhs.wales","quote":"This should include any medication and doses, as well as any dates that blood tests and follow-up appointments must be carried out.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-13","next_check_at":"2027-11-13","version":1},"alternatives":{"status":"missing","reason":"no_official_source","checked_at":"2026-11-13","next_check_at":"2027-02-11"},"technique_details":{"status":"ok","items":[{"id":"implantable-cervical-vagus","name":"Implantable cervical vagus nerve stimulator (lead on left cervical vagus nerve with chest-wall pulse generator)","how_it_works":{"text":"An implanted device sends electrical pulses to the neck nerve","source":{"url":"https://my.clevelandclinic.org/health/treatments/17598-vagus-nerve-stimulation","host":"my.clevelandclinic.org","quote":"Vagus nerve stimulation (VNS) uses an implantable device to stimulate the vagus nerve in your neck.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}},"recovery_daily":{"event":"back_to_daily_activities","min":2,"max":2,"unit":"days","label":"2 days","source":{"url":"https://my.clevelandclinic.org/health/treatments/17598-vagus-nerve-stimulation","host":"my.clevelandclinic.org","quote":"You can return to your everyday activities 48 hours after your device is implanted.","tier":"tier1_medical","fetched_at":"2026-11-13","http_status":200}}}],"checked_at":"2026-11-13","next_check_at":"2027-11-13","version":1}}},"hrefLanguages":[{"rel":"alternate","hreflang":"ru","language":"ru","href":"https://ru.bookimed.com/clinics/procedure=stimulyaciya-bluzhdauschego-nerva/page=5/"}],"questionsAndAnswers":[],"seoTests":{"thin_content":false,"no_txt_after_3_clinics":false},"offerFilters":{"offer_count":0,"price_filter":{"from":0,"to":0,"avg":0}},"leadsCount":{"leads_count":205},"manualSeo":[],"updatedAt":"2026-11-11T14:12:17.000Z","activeCountries":["TR","AT","ES","TH"],"hasVideoReviewsByContext":true,"hasCriticalApiFallback":false}