| #1 | | | Milan, Italy | | 57+ years8,000+ treatments | Atrial septal defect surgery | — | — | Scientific Institute for Research and Healthcare Accrediatation, World's Best Hospitals 2021 by Newsweek |
| #2 | | | Milan, Italy | | 46+ years8,000+ treatments | Minimally invasive cardiac surgery, hybrid techniques, percutaneous treatment, suturless prostheses | Complex congenital heart defects | Cardiac Surgery Unit performs 1,400 heart operations annually with hybrid robotic rooms. Surgeons have extensive experience in valve repair and congenital heart disease correction. | Scientific Institute for Research and Healthcare Accrediatation, World's Best Hospitals 2021 by Newsweek |