Best Multiple subpial transections neurologists in Istanbul: TOP 10 doctors

Dr. Nejat Akalan is a leading neurosurgeon specializing in brain and nerve surgeries, with over 35 years of experience. His areas of expertise include epilepsy, glioma, skull injuries, movement disorders, spine tumors, herniations, and other nervous disorders. He uses advanced techniques in his surgeries and has published 117 scientific papers and a book.

Neurosurgery Training: Gazi University, Department of Neurosurgery, 2011 

H index: 10, I10 Index: 12 Citations: 296

 Dr Mehmet Tonge has international and nationwide 32 publications, 12 book chapters, 92 oral and poster presentations and 41 invited lectures, mostly on Stereotactic and Functional Neurosurgery. 

Work & Training experience:

2004-2011: Gazi University, Department of Neurosurgery (Residency)

 2008: Zurich University Hospital, Department of Neurosurgery (Intraoperative MRI applications), Switzerland 

2008: Zurich University Hospital, Department of Neurosurgery: Microneurosurgery, white matter dissection, interventional neuroradiology courses, Switzerland 

2011 – 2012: Sinop Ataturk State Hospital, Neurosurgeon

 2012 – 2013: Cankiri State Hospital, Neurosurgeon 

2013 – 2014: Istanbul Medipol University, Department of Neurosurgery & Gamma Knife Center (Ass Prof) 

2013 – now: Maastricht University Neurosurgery & Neuroscience Department (Visiting scientist, PhDc) The Netherlands 

2014: Maastricht University, The Netherlands: Deep Brain Stimulation Fellowship 2014-2018: Istanbul Memorial Hospital Neurosurgery: Staff Neurosurgeon

 2016-2018: Istanbul Florence Nightingale Hospital (Consultant, Gamma Knife Center) 

2018-now: Istanbul Medipol University (Stereotactic & Functional Neurosurgery, Gamma Knife Center) Ass. Prof.) 

Dr Mehmet Tonge has completed 4-year cycle EANS (European Association of Neurosurgical Societies) Training courses. 

Clinical areas of interest:

 • Stereotactic & Functional Neurosurgery

 • Surgery for movement disorders

• * MR Guided Focused Ultrasound (MRgFUS)

 • Gamma Knife Radiosurgery 

• Surgery for pain & spasticity 

• Psychosurgery

Research areas of interest: 

• Deep brain stimulation

• * MR Guided Focused Ultrasound (MRgFUS)

 • Stereotactic radiosurgery 

Administrative duties:

 • Turkish Neurosurgical Society, Sterotactic & Functional Neurosurgery Section: Board member 2015- 2017 

• Turkish Neurosurgical Society, Sterotactic & Functional Neurosurgery Section: Board member (Secretary) 2017-2019

 • Turkish Skull Base Society: Board member 2016-2018

 • Turkish Skull Base Society: Supervisory board member 2018-2020

 • Deep Brain Stimulation and Movement Disorders Surgery Society: Executive Board Member, (Accountant) 2023-still 

Memberships: 

• WSSFN (World Stereotactic & Functional Neurosurgery Society) 

• ESSFN (European Stereotactic & Functional Neurosurgery Society)

 • Deep Brain Stimulation and Movement Disorders Surgery Society

 • Deep Brain Stimulation Society 

• International Stereotactic Radiosurgery Society 

• Leksell Gamma Knife Society 

• EANS (European Association of Neurosurgical Societies) 

• Turkish Neurosurgical Society

• Turkish Skull Base Society

Sample Publications: 

1. Tonge M. Technological developments in electric based DBS. Deep Brain Stimulation 2024 4(36-41) DOI: https://doi.org/10.1016/j.jdbs.2023.12.001 

2. Akgul E, Onan HB, Islek I, Tonge M, Durmus Y, Barburoglu M, Azizova A, Erol C, Hakyemez B, Sencer S, Aydin K, Arat A. Flow diverter stents in the treatment of recanalized intracranial aneurysms. Interv Neuroradiol. 2021 Aug;27(4):481-489. doi: 10.1177/1591019921990507. Epub 2021 Jan 28. PMID: 33509011; PMCID: PMC8580529. 

3. Mulders AEP, Temel Y, Tonge M, Schaper FLWVJ, van Kranen-Mastenbroek V,Ackermans L, Kubben P, Janssen MLF, Duits A. The association between surgical characteristics and cognitive decline following deep brain stimulation of the subthalamic nucleus in Parkinson's disease. Clin Neurol Neurosurg. 2021 Jan;200:106341. doi: 10.1016/j.clineuro.2020.106341. Epub 2020 Nov 3. PMID: 33160716. 

4. Wetzelaer P, Vlis T, Tonge M, Ackermans L, Kubben P, Evers S, Kocabicak E, Temel Y. Management of Hardware Related Infections after DBS Surgery: A Cost Analysis. Turk Neurosurg. 2018;28(6):929- 933. doi: 10.5137/1019-5149.JTN.21511-17.1. PMID: 29465741. 

5. Bedirli N, Emmez G, Ünal Y, Tönge M, Emmez H. Effects of positive end- expiratory pressure on intracranial pressure during pneumoperitoneum and Trendelenburg position in a porcine mode. Turk J Med Sci. 2017 Nov 13;47(5):1610-1615. doi: 10.3906/sag-1609-17. PMID: 29152942. 

6. Sari R, Tonge M, Bolukbasi FH, Onoz M, Baskan O, Silav G, Elmaci I. Management of Failed Cranioplasty. Turk Neurosurg. 2017;27(2):201-207. doi: 10.5137/1019-5149.JTN.15395-15.0. PMID: 27593759. 

7. Tonge M, Kocabicak E, Ackermans L, Kuijf M, Temel Y. Final Electrode Position in Subthalamic Nucleus Deep Brain Stimulation Surgery: A Comparison of Indirect and Direct Targeting Methods. Turk Neurosurg. 2016;26(6):900-903. doi: 10.5137/1019-5149.JTN.13739-14.1. PMID: 27337232. 

8. Tonge M, Ackermans L, Kocabicak E, van Kranen-Mastenbroek V, Kuijf M, Oosterloo M, Kubben P, Temel Y. A detailed analysis of intracerebral hemorrhages in DBS surgeries. Clin Neurol Neurosurg. 2015 Dec;139:183-7. doi: 10.1016/j.clineuro.2015.10.017. Epub 2015 Oct 23. PMID: 26513430. 

9. Silav G, Bölükbaşı FH, Özek E, Tönge M, Önöz M, Elmacı İ. A Simple Technique for Bone Storage after Decompressive Craniectomy in Children. Pediatr Neurosurg. 2015;50(3):161-4. doi: 10.1159/000381748. Epub 2015 May 14. PMID: 25998533. 

10. Yilmaz MB, Donmez H, Tonge M, Senol S, Tekiner A. Vertebrojugular arteriovenous fistula and pseudoaneurysm formation due to penetrating vertebral artery injury: case report and review of the literature. Turk Neurosurg. 2015;25(1):141-5. doi: 10.5137/1019-5149.JTN.8247-13.1. PMID: 25640560. 

11. Kurt G, Tönge M, Çeltıkçı E, Çapraz I, Serdaroğlu A, Bılır E. Surgery for intractable temporal lobe epilepsy: experience of a single institution. Turk J Med Sci. 2014;44(5):866-70. doi: 10.3906/sag-1307- 30. PMID: 25539559. 

12. Yılmaz MB, Tönge M, Emmez H, Kaymaz F, Kaymaz M. Neuroprotective effects of quetiapine on neuronal apoptosis following experimental transient focal cerebral ischemia in rats. J Korean Neurosurg Soc. 2013 Jul;54(1):1-7. doi: 10.3340/jkns.2013.54.1.1. Epub 2013 Jul 31. PMID: 24044072; PMCID: PMC3772279. 

13. Yilmaz MB, Egemen E, Tonge M, Kaymaz M. Transoral protrusion of a peritoneal catheter due to gastric perforation 10 years after a ventriculoperitoneal shunting: case report and review of the literature. Turk Neurosurg. 2013;23(2):285-8. doi: 10.5137/1019-5149.JTN.4904-11.1. PMID: 23546921. 

14. Omerhodzic I, Tonge M, Matos B, Musabeliu E, Raspanti C, Ferdinandov D, Galimova R, Muroi C, Balik V, Kursumovic A. Neurosurgical training programme in selected European countries: from the young neurosurgeons' point of view. Turk Neurosurg. 2012;22(3):286-93. doi: 10.5137/1019- 5149.JTN.5133-11.0. PMID: 22664994. 

15. Ergun E, Kurt G, Tonge M, Aytar H, Tas M, Baykaner K, Ceviker N. Effects of phenytoin sodium on dura mater healing in a rat model of CSF leakage. Turk Neurosurg. 2011;21(4):471-6. PMID: 22194102. 

16. Emmez H, Tonge M, Tokgoz N, Durdag E, Gonul I, Cevıker N. Radiological and histopathological comparison of microporous polysaccharide hemospheres and oxidized regenerated cellulose in the rabbit brain: a study of efficacy and safety. Turk Neurosurg. 2010 Oct;20(4):485-91. doi: 10.5137/1019- 5149.JTN.3300-10.2. PMID: 20963698. 

17. Emmez H, Yildirim Z, Kale A, Tönge M, Durdağ E, Börcek AO, Uçankuş LN, Doğulu F, Kiliç N, Baykaner MK. Anti-apoptotic and neuroprotective effects of α-lipoic acid on spinal cord ischemiareperfusion injury in rabbits. Acta Neurochir (Wien). 2010 Sep;152(9):1591-600; discussion 1600-1. doi: 10.1007/s00701-010-0703-9. Epub 2010 Jun 10. PMID: 20535507. 

18. Kurt G, Tonge M, Börcek AO, Karahacioglu E, Gurel O, Baykaner K, Ceviker N, Aykol S. Fractionated gamma knife radiosurgery for optic nerve tumors: a technical report. Turk Neurosurg. 2010 Apr;20(2):241-6. doi: 10.5137/1019-5149.JTN.1681-09.3. PMID: 20401852. 

19. Emmez H, Kale A, Tönge M, Cakir A, Ceviker N. Two meningiomas with different histological grades in the same patient. Case report. Neurol Med Chir (Tokyo). 2010;50(8):686-8. doi: 10.2176/nmc.50.686. PMID: 20805656.

2002-2007 Istanbul University Istanbul Faculty of Medicine Department of Brain and Nerve Surgery

1988-1995 Trakya University Faculty of Medicine

2015- Atlas University Medicine Hospital

2014-2015 Private Pendik Yüzyıl Hospital Brain and Neurosurgery Clinic

2009-2014 Medicine Hospital Brain and Neurosurgery Clinic

2009-2009 Nisa Hospital Brain and Neurosurgery Clinic

2007-2009 Mardin State Hospital Brain and Neurosurgery Clinic

2002-2007 Istanbul University Istanbul Faculty of Medicine Brain and Neurosurgery

1997-2001 Enez Health Center and Enez State Hospital

Cervical, Thoracic and Lumbar Disc Surgery (endoscopic/microsurgery)

Far lateral (non-canal) lumbar disc surgery (lateral microsurgical approach)

Neurovascular surgery

Cerebrovascular diseases (vascular diseases of the brain)

Aneurysms

Arteriovenous malformations

Cavernomas

Neuro-oncological surgery

Brain tumors

Glial tumors

Meningiomas

Pituitary gland tumors

Metastatic brain tumors

Skull base tumors

Pontocerebellar angle tumors

Pineal tumors

Intraventricular tumors

Spinal disease surgery

Cervical, thoracic and lumbar spine fractures

Spine and spinal cord tumors

Scoliosis

Degenerative spine diseases

Peripheral nerve disease surgery

Peripheral nerve tumors

Entrapment neuropathies

Carpal tunnel syndrome

Ulnar groove syndrome

Tarsal tunnel syndrome

Functional neurosurgery and pain surgery

Trigeminal neuralgia

Microvascular decompression

Epilepsy surgery

Spasticity surgery

Epiduroscopic interventions

Hydrocephalus surgeries

Endoscopic 3rd ventriculostomy

VP shunt surgeries

LP shunt surgeries

Developmental anomalies

Meningomyelocele

Tethered cord syndrome

Arachnoid cyst

Craniosynostosis surgeries

Chiari malformation

Head trauma

Subdural hematomas

Intracerebral hematomas

Article published in internationally refereed journals

Cansever T, Civelek E, Sencer A, Karasu A, Kiris T, Hepgül K, Can H, Canbolat A: Spinal cavernous malformations: a report of 5 cases. Surg Neurol Jun 69 

Effects of combined and individual use of N-methyl-D aspartate receptor antagonist magnesium sulphate and caspase-9 inhibitor z-LEDH-fmk experimental spinal cord injury. A.Sencer, A.Aydoseli, Y.Aras, M.Osman Akçakaya, C.Gömleksiz, H.Can, A.Canbolat. Turkısh Joumal of Trauma&Emergency Surgery 2013

Aydoseli A, Can H, Aras Y, Sabanci PA, Akcakaya MO, Unal OF. Memantine and Q-VD-OPh Treatments in Experimental Spinal Cord Injury: Combined Inhibition of Necrosis and Apoptosis. Turk Neurosurg. 2016

Can H, Kircelli A, Kavadar G, Civelek E, Cansever T, Aydoseli A, Onal MB, Yilmaz C. Lumbosacral Conjoined Root Anomaly: Anatomical Considerations of Exiting Angles and Root Thickness. Turk Neurosurg. 2017

Kırcelli A, Özel Ö, Can H, Sarı R, Cansever T, Elmacı İ. Is the presence of linear fracture a predictor of delayed posterior fossa epidural hematoma? Ulus Travma Acil Cerrahi Derg. 2016 Jul

Kavadar G, Demircioğlu DT, Can H, Emre TY, Civelek E, Senyigit A. The clinical factors associated with benefit finding of complementary medicine use in patients with back pain: A cross-sectional study with cluster analysis. J Back Musculoskelet Rehabil. 2017

Ozer AF, Suzer T, Can H, Falsafi M, Aydin M, Sasani M, Oktenoglu T. Anatomic Assessment of Variations in Kambin’s Triangle: A Surgical and Cadaver Study. World Neurosurg. 2017 Apr

Can H, Aydoseli A, Gömleksiz C, Göker B, Altunrende ME, Dolgun M, Sencer A. Combined and individual use of pancaspase inhibitor Q-VD-OPh and NMDA receptor antagonist riluzole in experimental spinal cord injury. Ulus Travma Acil Cerrahi Derg. 2017

Gomleksiz C, Erbulut DU, Can H, Kodigudla MK, Kelkar AV, Kasapoglu E, Ozer AF, Goel VK. A new lumbar fixation device alternative to pedicle-based stabilization for lumbar spine: In vitro cadaver investigation. J Spinal Cord Med. 2018 Jul 16:1-8.

Aydoseli A, Özgen U, Akgül T, Orhan EK, Adıyaman AE, Can H, Karadağ C. Subacute Traumatic Ascending Myelopathy in a 28-year-old man: A rare case. World Neurosurg. 2019 Apr 28

Article published in national refereed journals

1) Intracranial Hemangioblastomas: Clinical Evaluation of 32 Patients T. Cansever, A. Karasu, K. Hepgül, H. Can, A. Sencer Turkish Neurosurgical Journal 2007, Volume:17 

2) Halil Can, Müge Dolgun, Utku Özgen, Cengiz Gömleksiz, Furkan Diren, Aydın Aydoseli, Yavuz Aras, Altay Sencer. Microsurgical Results in Vestibular Schwannoma Patients; Retrospective Clinical Study. JAREM 2019

3) Furkan Diren , Özcan Gayretli , Halil Can , İlke Ali Gürses , Orhan Barlas. Examination of Pons-Cerebellum Cisterna Anatomy with Endoscopic Retrosigmoid Suboccipital Approach: Cadaver Study. JAREM 2019

He was born in Niğde which is the city middle part of Anatolia. He studied high school in Adana. He graduated from Ankara University Medical School of Medicine. He started his career at Bakırköy Neurological Sciences Hospital in Zeki Oral MD.’s Clinic in 1987 and finished his Neurosurgery residency in 1993. During this period, he completed his micro neurosurgery education, which was a breakthrough for him, at Zurich University “Professor M. Gazi Yaşargil’s Clinic”.

Between 1993-2003, he worked as a teaching assistant and then as an assistant professor at the Professor Necmettin Pamir’s Clinic, Faculty of Medicine, Marmara University. At the same time, he obtained clinical and surgical gains in the field of neurooncology and vascular neurosurgery at Professor Donlin M. Long and Daniele Rigamonti's Clinic at Johns Hopkins University, USA. In 2003, he received the title of Associate Professor of Neurosurgery.

Between 2004-2010, he worked as Chief of Clinic in Göztepe Training and Research Hospital of Ministry of Health. During this period, he led his clinic to become the only accredited clinic by EANS (The European Association of Neurosurgical Societies) in Turkey, with its educational and care services. During this period, he completed his endoscopic skull base training starting at the University of Pittsburgh.

In 2010, he started to work for Acıbadem University Faculty of Medicine and became a Professor of Neurosurgery. He established the Neurosurgery Department in Medipol University Faculty of Medicine on 2012. He served as a Head of Neurosurgery Department in Memorial Health Group Istanbul Hospitals between 2014-2018. He served Neurosurgery Department of Maslak Hospital of Acıbadem Health Group with his team between 2018- September 2021.

Since 01.10.2021, He have started to work with his team at my private clinic located in Fulya and Ulus Hospital of Liv Health Group.

He served as the founding chairman of ”Skull Base Society” in Turkey. He is also a member of the Executive Committee of the European Skull Base Society (ESBS).

There are more than 110 scientific papers which he hs published in international refereed journals (SCI/SCIEx) and in national refereed journals and 18 scientific articles. He Has more than 250 scientific congress presentations, published books and chapters in books.

Certificates

1. The Course of Functional and Stereotactic Neurosurgery, 1990, Oulu, Finland.

2. European Course participation that holds by EANS for 5 years cycle (Amsterdam/1988, Rostock/1989, Çeşme/1994, Klagenfurt/1995, Aalborg/1996).

3. "Primary Examination" for European Board was passed in Klagenfurt,1995, Austria.

4."Advanced Training on Functional Disorders with Leksell Gamma Knife", 2004, Marseille, France.

5. "Advanced Training on Vestibular Schwannomas and Skull Base Surgery wiyh Leksell Gamma Knife", 2004, Marseille, France.

6. The certificate for "DISC Nucleoplasty in Cervical and Lumbar Disc Diseases", 2004, Freiburg, Germany.

7. "Neuropathfinder" Train - the - Trainer Meeting, 2009, Wien, Austria.

8. " Neuropathfinder" Train - the - Trainer Meeting, 2011, Athens, Greece.

9. The certificate for "Full- Endoscopic Spine Surgery", 2011, Herne, Germany.

General Information and Presentation

He completed his primary education at Şenlikköy Primary School and his secondary education at the Istek Foundation Florya Bilge Kagan High School. He graduated from Istanbul University Cerrahpaşa Faculty of Medicine in 2001. He completed his specialist education in Istanbul Medical Faculty Neurology Department in 2006. In 2006 he worked at the Neurology Clinic and the PharmaZentrum Research Center of the Faculty of Medicine of the University of Basel, Switzerland. Between 2007 and 2011, Bakırköy Prof. Dr. He worked at Mazhar Osman Mental Health and Neurological Diseases Training and Research Hospital in the 3rd Neurology Clinic and in the Dementia and Movement Disorders policlinics. Since October 2011, he has been working at Istanbul University of Science, Faculty of Medicine, Neurology, USA.

Experience

İstanbul Bilim University Faculty of Medicine Neurology, 

Şişli Florence Nightingale Hospital 

Kadıköy Florence Nightingale Hospital Neurology Clinics, 

Gayrettepe Metropolitan Florence Nightingale Hospital PET department.

Education:

Medical Faculty, Trakya University,  

Edirne, Turkey (1994-2000)

Professional Experience:

General Practitioner and Emergency Physician

Bartın (2000-2004)

Specialization:  

Department of Neurosurgery, S.B. Göztepe Training and Research Hospital,  

Istanbul (2004-2010)

Participation in the Accreditation Process by the European Association of Neurosurgical Societies (EANS) during  

Specialization (2004-2010)

Completion of Compulsory Service as Specialist Physician

Tokat State Hospital, Tokat (2010-2012)

Assistant Professor, Department of Neurosurgery

Gaziosmanpaşa University, Tokat (2012-2014)

Contribution to the Establishment of the Department of Neurosurgery at Medipol University  

(2012-2014)

Lecturer

Medipol University, Istanbul (2012-2014)

Specialist Physician

Memorial Istanbul Hospitals, Istanbul (2014-2018)

Lecturer, Faculty of Health Sciences

Eurasia University, Istanbul (2014-2021)

Associate Professor in the field of Neurosurgery (2021- )

Specialist Physician

Acıbadem Maslak Hospital, Istanbul (2018-2021)

Specialist Physician

Liv Hospital Ulus, Istanbul (2021-2023)

2023 –

Istanbul Florence Nightingale Hospital, Istanbul

Skills and Achievements:

Obtained Associate Professorship in the field of Neurosurgery (2021)

Experience in Academic Teaching and Management (2012-2021)

Proficiency in Turkish (Native) and English (Advanced)

Specializations

Brain Tumors

Aneurysm Surgery

Pituitary Surgery

Spine Surgery

Waist neck and back hernias

Spine Tumors

Spinal Fractures

Peripheral Nerve Surgery