Best Medication treatment for multiple sclerosis neurosurgeons in Istanbul: TOP 20 doctors

Gülümser Kızıltaş Tokmak, M.D., graduated from Cerrahpaşa School of Medicine, Istanbul University in 2002 and completed residency at Neurology Clinic, Okmeydanı Teaching and Research Hospital in 2008. She holds a master’s degree in Electrophysiology from Istanbul University, and has studied and worked in fields such as EMG, EEG, PSG, Dementia, Headache, and Vertigo. She has worked at Ağrı State Hospital Neurology Clinic, Hisar Intercontinental Hospital, and Medical Park Hospitals.

Dr. Nejat Akalan is a leading neurosurgeon specializing in brain and nerve surgeries, with over 35 years of experience. His areas of expertise include epilepsy, glioma, skull injuries, movement disorders, spine tumors, herniations, and other nervous disorders. He uses advanced techniques in his surgeries and has published 117 scientific papers and a book.

He was born in 1978 in Prizren (Kosovo). After graduating from "Prizren Science High School" in 1996, he started his education at Pristina University Faculty of Medicine in 1996 and graduated from Kocaeli University Faculty of Medicine between 1999-2005. Between 2006-2011, he completed his specialty training in Neurology at Marmara University Faculty of Medicine, Department of Neurology. During her training, she was especially interested in electrophysiology, dementias and movement disorders. Between 2012-2013, she worked as a lecturer at Üsküdar University. Since 2013, she has been working as a Neurology specialist at NPIstanbul Brain Hospital. She has ongoing scientific studies in the field of neurology. He speaks fluent English, Serbian and Bosnian. In his free time, he is engaged in classical Turkish music.

Publications:

• Bilateral Thalamic Anaplastic Glioma: Case Report. Ibrahim Sun, Celal Salcini , Ayca Sun, Baran Yılmaz, Kadriye Agan. Marmara Medical Journal 2008, Volume 21, Issue 3, Page(s) 257-260
• Electrophysiology and Pathology Findings in a Case of Lafora. Ağan K, Erbaş B, Şalçini C, Uluç K, Günal D, Aktan S. 42nd National Neurology Congress, 2006
• Tumefactive MS: A Case Report. Deniz Borucu, Celal Şalçini, Betül Özdilek, Kayıhan Uluç, Neşe Tuncer Elmacı, Dilek İnce Günal. 43rd National Neurology Congress, 2007
• Creutzfeldt-Jacob Disease; Case Report with Radiologic and CSF Findings. Orhan Yılmaz, Celal Şalçini, Mesrure Köseoğlu, Kayıhan Uluç, İpek Midi, Neşe Tuncer,Önder Us, 43rd National Neurology Congress, 2007
• A Case of Tardive Dystonia Secondary to Low Dose Risperidone. Celal Şalçini, Kadriye Ağan, Dilek İnce Günal, 8th National Parkinson and Movement Disorders Congress, 2009
• Transcranial Direct Current Stimulation in a Patient With Schizoaffective Disorder Manic Episode. Gökben Hızlı Sayar, Celal Salcini, Ali Bayram, Gaye Kağan, Nevzat Tarhan, 2012
• Chapter XVI "SPINAL CORD DISEASES" of Merrit's Neurology Handbook, p:493-502 Uz.Dr. Kayıhan Uluç, Dr. Celal Şalçini, Translation editor O. Doğu, Güneş Tıp Kitapevleri, ISBN No: 978-975-277-207-6, Ankara 2009
• Neurophysiologic Approach to the Complex Organization in Spine: A study on F-wave duration and Cutaneous Silent Period in Primary Restless Legs Patients, İşak B., Uluç K., Şalçini C., Clinical Neuorphysyology, 2010

2002-2007 Istanbul University Istanbul Faculty of Medicine Department of Brain and Nerve Surgery

1988-1995 Trakya University Faculty of Medicine

2015- Atlas University Medicine Hospital

2014-2015 Private Pendik Yüzyıl Hospital Brain and Neurosurgery Clinic

2009-2014 Medicine Hospital Brain and Neurosurgery Clinic

2009-2009 Nisa Hospital Brain and Neurosurgery Clinic

2007-2009 Mardin State Hospital Brain and Neurosurgery Clinic

2002-2007 Istanbul University Istanbul Faculty of Medicine Brain and Neurosurgery

1997-2001 Enez Health Center and Enez State Hospital

Cervical, Thoracic and Lumbar Disc Surgery (endoscopic/microsurgery)

Far lateral (non-canal) lumbar disc surgery (lateral microsurgical approach)

Neurovascular surgery

Cerebrovascular diseases (vascular diseases of the brain)

Aneurysms

Arteriovenous malformations

Cavernomas

Neuro-oncological surgery

Brain tumors

Glial tumors

Meningiomas

Pituitary gland tumors

Metastatic brain tumors

Skull base tumors

Pontocerebellar angle tumors

Pineal tumors

Intraventricular tumors

Spinal disease surgery

Cervical, thoracic and lumbar spine fractures

Spine and spinal cord tumors

Scoliosis

Degenerative spine diseases

Peripheral nerve disease surgery

Peripheral nerve tumors

Entrapment neuropathies

Carpal tunnel syndrome

Ulnar groove syndrome

Tarsal tunnel syndrome

Functional neurosurgery and pain surgery

Trigeminal neuralgia

Microvascular decompression

Epilepsy surgery

Spasticity surgery

Epiduroscopic interventions

Hydrocephalus surgeries

Endoscopic 3rd ventriculostomy

VP shunt surgeries

LP shunt surgeries

Developmental anomalies

Meningomyelocele

Tethered cord syndrome

Arachnoid cyst

Craniosynostosis surgeries

Chiari malformation

Head trauma

Subdural hematomas

Intracerebral hematomas

Article published in internationally refereed journals

Cansever T, Civelek E, Sencer A, Karasu A, Kiris T, Hepgül K, Can H, Canbolat A: Spinal cavernous malformations: a report of 5 cases. Surg Neurol Jun 69 

Effects of combined and individual use of N-methyl-D aspartate receptor antagonist magnesium sulphate and caspase-9 inhibitor z-LEDH-fmk experimental spinal cord injury. A.Sencer, A.Aydoseli, Y.Aras, M.Osman Akçakaya, C.Gömleksiz, H.Can, A.Canbolat. Turkısh Joumal of Trauma&Emergency Surgery 2013

Aydoseli A, Can H, Aras Y, Sabanci PA, Akcakaya MO, Unal OF. Memantine and Q-VD-OPh Treatments in Experimental Spinal Cord Injury: Combined Inhibition of Necrosis and Apoptosis. Turk Neurosurg. 2016

Can H, Kircelli A, Kavadar G, Civelek E, Cansever T, Aydoseli A, Onal MB, Yilmaz C. Lumbosacral Conjoined Root Anomaly: Anatomical Considerations of Exiting Angles and Root Thickness. Turk Neurosurg. 2017

Kırcelli A, Özel Ö, Can H, Sarı R, Cansever T, Elmacı İ. Is the presence of linear fracture a predictor of delayed posterior fossa epidural hematoma? Ulus Travma Acil Cerrahi Derg. 2016 Jul

Kavadar G, Demircioğlu DT, Can H, Emre TY, Civelek E, Senyigit A. The clinical factors associated with benefit finding of complementary medicine use in patients with back pain: A cross-sectional study with cluster analysis. J Back Musculoskelet Rehabil. 2017

Ozer AF, Suzer T, Can H, Falsafi M, Aydin M, Sasani M, Oktenoglu T. Anatomic Assessment of Variations in Kambin’s Triangle: A Surgical and Cadaver Study. World Neurosurg. 2017 Apr

Can H, Aydoseli A, Gömleksiz C, Göker B, Altunrende ME, Dolgun M, Sencer A. Combined and individual use of pancaspase inhibitor Q-VD-OPh and NMDA receptor antagonist riluzole in experimental spinal cord injury. Ulus Travma Acil Cerrahi Derg. 2017

Gomleksiz C, Erbulut DU, Can H, Kodigudla MK, Kelkar AV, Kasapoglu E, Ozer AF, Goel VK. A new lumbar fixation device alternative to pedicle-based stabilization for lumbar spine: In vitro cadaver investigation. J Spinal Cord Med. 2018 Jul 16:1-8.

Aydoseli A, Özgen U, Akgül T, Orhan EK, Adıyaman AE, Can H, Karadağ C. Subacute Traumatic Ascending Myelopathy in a 28-year-old man: A rare case. World Neurosurg. 2019 Apr 28

Article published in national refereed journals

1) Intracranial Hemangioblastomas: Clinical Evaluation of 32 Patients T. Cansever, A. Karasu, K. Hepgül, H. Can, A. Sencer Turkish Neurosurgical Journal 2007, Volume:17 

2) Halil Can, Müge Dolgun, Utku Özgen, Cengiz Gömleksiz, Furkan Diren, Aydın Aydoseli, Yavuz Aras, Altay Sencer. Microsurgical Results in Vestibular Schwannoma Patients; Retrospective Clinical Study. JAREM 2019

3) Furkan Diren , Özcan Gayretli , Halil Can , İlke Ali Gürses , Orhan Barlas. Examination of Pons-Cerebellum Cisterna Anatomy with Endoscopic Retrosigmoid Suboccipital Approach: Cadaver Study. JAREM 2019

He was born in Niğde which is the city middle part of Anatolia. He studied high school in Adana. He graduated from Ankara University Medical School of Medicine. He started his career at Bakırköy Neurological Sciences Hospital in Zeki Oral MD.’s Clinic in 1987 and finished his Neurosurgery residency in 1993. During this period, he completed his micro neurosurgery education, which was a breakthrough for him, at Zurich University “Professor M. Gazi Yaşargil’s Clinic”.

Between 1993-2003, he worked as a teaching assistant and then as an assistant professor at the Professor Necmettin Pamir’s Clinic, Faculty of Medicine, Marmara University. At the same time, he obtained clinical and surgical gains in the field of neurooncology and vascular neurosurgery at Professor Donlin M. Long and Daniele Rigamonti's Clinic at Johns Hopkins University, USA. In 2003, he received the title of Associate Professor of Neurosurgery.

Between 2004-2010, he worked as Chief of Clinic in Göztepe Training and Research Hospital of Ministry of Health. During this period, he led his clinic to become the only accredited clinic by EANS (The European Association of Neurosurgical Societies) in Turkey, with its educational and care services. During this period, he completed his endoscopic skull base training starting at the University of Pittsburgh.

In 2010, he started to work for Acıbadem University Faculty of Medicine and became a Professor of Neurosurgery. He established the Neurosurgery Department in Medipol University Faculty of Medicine on 2012. He served as a Head of Neurosurgery Department in Memorial Health Group Istanbul Hospitals between 2014-2018. He served Neurosurgery Department of Maslak Hospital of Acıbadem Health Group with his team between 2018- September 2021.

Since 01.10.2021, He have started to work with his team at my private clinic located in Fulya and Ulus Hospital of Liv Health Group.

He served as the founding chairman of ”Skull Base Society” in Turkey. He is also a member of the Executive Committee of the European Skull Base Society (ESBS).

There are more than 110 scientific papers which he hs published in international refereed journals (SCI/SCIEx) and in national refereed journals and 18 scientific articles. He Has more than 250 scientific congress presentations, published books and chapters in books.

Certificates

1. The Course of Functional and Stereotactic Neurosurgery, 1990, Oulu, Finland.

2. European Course participation that holds by EANS for 5 years cycle (Amsterdam/1988, Rostock/1989, Çeşme/1994, Klagenfurt/1995, Aalborg/1996).

3. "Primary Examination" for European Board was passed in Klagenfurt,1995, Austria.

4."Advanced Training on Functional Disorders with Leksell Gamma Knife", 2004, Marseille, France.

5. "Advanced Training on Vestibular Schwannomas and Skull Base Surgery wiyh Leksell Gamma Knife", 2004, Marseille, France.

6. The certificate for "DISC Nucleoplasty in Cervical and Lumbar Disc Diseases", 2004, Freiburg, Germany.

7. "Neuropathfinder" Train - the - Trainer Meeting, 2009, Wien, Austria.

8. " Neuropathfinder" Train - the - Trainer Meeting, 2011, Athens, Greece.

9. The certificate for "Full- Endoscopic Spine Surgery", 2011, Herne, Germany.

General Information and Presentation

He completed his primary education at Şenlikköy Primary School and his secondary education at the Istek Foundation Florya Bilge Kagan High School. He graduated from Istanbul University Cerrahpaşa Faculty of Medicine in 2001. He completed his specialist education in Istanbul Medical Faculty Neurology Department in 2006. In 2006 he worked at the Neurology Clinic and the PharmaZentrum Research Center of the Faculty of Medicine of the University of Basel, Switzerland. Between 2007 and 2011, Bakırköy Prof. Dr. He worked at Mazhar Osman Mental Health and Neurological Diseases Training and Research Hospital in the 3rd Neurology Clinic and in the Dementia and Movement Disorders policlinics. Since October 2011, he has been working at Istanbul University of Science, Faculty of Medicine, Neurology, USA.

Experience

İstanbul Bilim University Faculty of Medicine Neurology, 

Şişli Florence Nightingale Hospital 

Kadıköy Florence Nightingale Hospital Neurology Clinics, 

Gayrettepe Metropolitan Florence Nightingale Hospital PET department.

Education:

Medical Faculty, Trakya University,  

Edirne, Turkey (1994-2000)

Professional Experience:

General Practitioner and Emergency Physician

Bartın (2000-2004)

Specialization:  

Department of Neurosurgery, S.B. Göztepe Training and Research Hospital,  

Istanbul (2004-2010)

Participation in the Accreditation Process by the European Association of Neurosurgical Societies (EANS) during  

Specialization (2004-2010)

Completion of Compulsory Service as Specialist Physician

Tokat State Hospital, Tokat (2010-2012)

Assistant Professor, Department of Neurosurgery

Gaziosmanpaşa University, Tokat (2012-2014)

Contribution to the Establishment of the Department of Neurosurgery at Medipol University  

(2012-2014)

Lecturer

Medipol University, Istanbul (2012-2014)

Specialist Physician

Memorial Istanbul Hospitals, Istanbul (2014-2018)

Lecturer, Faculty of Health Sciences

Eurasia University, Istanbul (2014-2021)

Associate Professor in the field of Neurosurgery (2021- )

Specialist Physician

Acıbadem Maslak Hospital, Istanbul (2018-2021)

Specialist Physician

Liv Hospital Ulus, Istanbul (2021-2023)

2023 –

Istanbul Florence Nightingale Hospital, Istanbul

Skills and Achievements:

Obtained Associate Professorship in the field of Neurosurgery (2021)

Experience in Academic Teaching and Management (2012-2021)

Proficiency in Turkish (Native) and English (Advanced)

Specializations

Brain Tumors

Aneurysm Surgery

Pituitary Surgery

Spine Surgery

Waist neck and back hernias

Spine Tumors

Spinal Fractures

Peripheral Nerve Surgery