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Last updated: 10/7/2025

Trans-sphenoidal hypophysectomy (adenomectomy) in Germany: Our Best Clinics and Costs 2025

85 %
patient recommendation
21 K+
patients
820К+ patients have got assistance since 2014
50 countries
1,500 clinics
6K+ reviews
3K+ qualified doctors

How Much Does Trans-sphenoidal hypophysectomy (adenomectomy) Cost in Germany?

The cost of trans-sphenoidal hypophysectomy (adenomectomy) in Germany typically ranges from $22,000 to $35,000. Prices vary depending on the hospital, the neurosurgeon’s expertise, whether the approach is endoscopic or microscopic, and the complexity of the tumor. In the United States, the average cost is $85,000 (per AANS). This means trans-sphenoidal hypophysectomy in Germany is about 66% less expensive than in the U.S.

German hospitals usually include pre-operative diagnostics (MRI, blood work), the surgery itself, anesthesia, surgical materials, several days of inpatient care, and post-op monitoring. In the U.S., hospital, anesthesia, and imaging fees are often billed separately, with the listed price covering only the surgeon’s fee. Patients should confirm which services, follow-ups, and imaging are included at each German clinic.

Key Benefits

Why choose Germany for trans-sphenoidal hypophysectomy (adenomectomy)?

  • Accredited clinics: Clinics in Germany hold recognition from the KTQ (Cooperation for Transparency and Quality in Healthcare). This ensures they maintain high standards of medical care.
  • Latest technologies: The use of techniques such as endoscopic endonasal approaches and neuronavigation systems like Brainlab, along with surgical instruments from brands like Karl Storz, enhances precision and outcomes.
  • High success rates: Trans-sphenoidal hypophysectomy (adenomectomy) in Germany has an efficacy rate of up to 95% for non-invasive pituitary adenomas. The procedures also have low complication rates.
  • Expert surgeons: Leading neurosurgeons in Germany often hold certifications from the German Society of Neurosurgery (DGNC). They perform over 500 successful procedures annually, showcasing their expertise and experience.

Access advanced Trans-sphenoidal hypophysectomy (adenomectomy) solutions in trusted clinics .

GermanyTurkeyAustria
Trans-sphenoidal hypophysectomy (adenomectomy)from $22,000from $6,560from $25,000
Data verified by Bookimed as of December 2025, based on patient requests and official quotes from 43 clinics worldwide. Median costs are based on real invoices (2024–2025) and updated monthly. Actual prices may vary.
Authored by Anna Leonova
Head of Content Marketing Team

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Discover the Best Trans-sphenoidal hypophysectomy (adenomectomy) Clinics in Germany: 2 Verified Options and Prices

The Bookimed clinic ranking is based on data science algorithms, providing a trusted, transparent, and objective comparison. It takes into account patient demand, review scores (both positive and negative), the frequency of updates to treatment options and prices, response speed, and clinic certifications.

Trans-sphenoidal hypophysectomy (adenomectomy) Overview in Germany

Takeaways
Related procedures & Costs
How it works
What to expect
Benefits
Payment
patients recommend -
85%
Surgery Time - 2 hours
Stay in the country - 7 days
Rehabilitation - 1 day
Anesthesia - General anesthesia
Requests processed - 21657
Verified patient reviews - 20
Bookimed fees - $0

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Reviews about Bookimed: Discover Patients' Insights

All reviews
Валерий • Herniated disk
Ukraine
Jan 21, 2020
Verified review.
"We definitely would not have such a result
I did a similar operation 20 years ago in Germany - now it’s definitely better, now the postoperative period has been reduced to a day and it is less painful. The hospital is good, double ward and the conditions are comfortable. There is a shower in the room, it’s convenient. We spoke with Ralph Bull, a doctor before the operation. After the first consultation, there remained uncertainty whether to do the operation or not. In this regard, doctors are careful and if there is a risk of surgery with complications, they can offer injections and physiotherapy, which is cheaper and safer. Nevertheless, in my case, the doctor once again reviewed the MRI and decided to do the operation. Adequate treatment, do not inject too much, gave pain medication. In general, everything is fine, the postoperative period is small and everything is good so far. We definitely would not have such a result.
Medical Center in SolingenRalf Buhl
Viktoriia Solikha • Brain tumor
Ukraine
Sep 16, 2019
Verified review.
- No one tried to scare or speed up the treatment process, but on the contrary, explained the risks and different methods of treatment, which encouraged and inspired hope for a favorable resolution of my problem
Good evening !!! I was in the clinic for a consultation in early September. Dr. Bul and the staff are very polite, attentive, calm, and what is surprising, they are not trying to make money on you, but they offer options for cheaper treatment and testing. No one tried to scare or speed up the treatment process, but on the contrary, explained the risks and different methods of treatment, which encouraged and inspired hope for a favorable resolution of my problem.
About Bookimed service
I am completely satisfied, as they answered all the questions posed, coordinated and accompanied me from the moment I went to the clinic until I returned home.
Medical Center in SolingenRalf Buhl
Ihor Sushko • Herniated disk
Ukraine
Aug 9, 2019
Verified review.
I advise all friends now Bookimed will always help
In general, the impressions are certainly positive, and it is impossible to compare with our medicine. And according to the statistics of the treatment of my problem itself, the effectiveness is of course much higher. Of course, it’s hard with the language barrier, except for our girls in the international center, I didn’t hear a Russian word in 7 days, it was certainly difficult, and in principle translators also helped when I was with them. I advise all friends now Bookimed will always help.
Medical Center in Solingen
Anonymous • Herniated disk
Azerbaijan
Jun 24, 2019
Verified review.
I can say that the patients would write down all their questions in advance, so that later they would not think that they should ask the doctor, you also need to think in advance what you want in principle from the consultation and then it will definitely be useful
Everything is fine, they arranged a remote consultation to understand whether it is possible to perform an operation. This format is definitely needed, very useful. I can say that the patients would write down all their questions in advance, so that later they would not think that they should ask the doctor, you also need to think in advance what you want in principle from the consultation and then it will definitely be useful.
Nordwest Clinic (Krankenhaus)
Ольга • Spondylolisthesis
Ukraine
Apr 30, 2019
Verified review.
"I was very pleased with the clinic, the doctors and the company Bukibmed, and I can recommend the professors Buhl and Flo
Good day. Operated on 10.04.2019 spondealistez at the doctors of Bul and Flo, joint operation of a neurosurgeon and an orthopedist. Doctors are beautiful with golden hands. Actually because of these doctors this clinic was chosen, and in this many thanks to the coordinator Alyona. The surgery went great, recovery after surgery, under the close supervision of doctors and physiotherapists, also went well. The clinic itself is on the level of convenience of an average private clinic in Kiev. The staff is attentive and always ready to help. The chamber was spacious, clean and bright. The work of the international department was a little upset, they were allowed to sign documents in German without a paper translation at least into English, I’m not talking about the Russian language. Sometimes they consulted with doctors in German, without literally translating what they were talking about. But despite this, I was very pleased with the clinic, the doctors and the company Bukibmed, and I can recommend the professors Buhl and Flo.
Medical Center in Solingen
Anonymous • Spinal stenosis
Kenya
Feb 17, 2020
Verified review.
I did an online consultation with the doctor thou was expecting a good feedback but instead it turned out to be a heartbreaking one but it was a fact maybe that I didn't knew but otherwise they are average.
About Bookimed service
Yes I was satisfied.
Bremen-Mitte Clinic
Muhammad Seleem • Brain tumor
Kuwait
Apr 25, 2024
Verified review.
All in all, the experience was excellent
All in all, the experience was excellent. The only issue that I had was the delay that I am facing in receiving the doctor’s report.
The facility is good.
Delay in getting the report.
Medical Center in Solingen
TATIANA MARICHEVA • Brain tumor
Russian Federation
Sep 4, 2019
Verified review.
He gave an exhaustive consultation!
The clinic is good, Dr. Bull is a neurosurgeon, a high professional in oncology, he gave an exhaustive consultation!
Medical Center in SolingenRalf Buhl

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Updated: 04/25/2024
Authored by
Anna Leonova
Anna Leonova
Head of Content Marketing Team
A certified medical writer with 10+ years of experience, developed Bookimed’s trusted content, backed by a Master’s in Philology and medical expert interviews worldwide.
Anna Leonova Linkedin
Reviewed by Bookimed Medical Advisor
Fahad Mawlood
Medical Editor & Data Scientist
General practitioner. Winner of 4 scientific awards. Served in Western Asia. Former Team Leader of a medical team supporting Arabic-speaking patients. Now responsible for data processing and medical content accuracy.
Fahad Mawlood Linkedin
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