Best Heart Valve Replacement Clinics in Italy: 6 Top-Rated Centers

San Donato Hospital performs over 20,000 heart valve operations annually with a 97% success rate that exceeds European standards. The procedure may cost around €40,000, typically covering the surgery and pre-evaluation. As Italy’s #1 cardiac surgery unit, the hospital offers both open and minimally invasive approaches, including TAVI, with world-class specialists like Prof. Maisano on staff. The IRCCS-accredited facility maintains rigorous quality standards.

IRCCS Ospedale Galeazzi - Sant'Ambrogio is recognized for its cardiovascular unit, specializing in heart valve replacement procedures. The hospital combines expertise from two renowned institutions, offering advanced cardiac care. Heart valve replacement typically costs between $1,400 and $4,500.

With 1,400 heart operations performed annually, Ospedale San Raffaele specializes in minimally invasive valve replacement using robot-assisted techniques with 3D cameras. The estimated cost for heart valve replacement surgery is around €50,000. This leading European research hospital is part of Gruppo San Donato and holds ISO certification, offering advanced cardiac care with direct metro access from Milan airports.

Dr. Giuseppe Speziale specializes in minimally invasive heart valve replacements, with thousands of complex procedures performed. He trained at La Sapienza University and leads cardiac surgery departments across Italy. The procedure may cost around $43,350–$50,390. Dr. Speziale is Vice President of GVM Care & Research and an active member of major cardiac societies.

Maria Cecilia Hospital handles over 15% of Italy's cardiac surgeries, specializing in complex heart valve replacements with a multidisciplinary Heart Team. The procedure typically costs around $2,600–$6,400. Dr. Carlo Savini, an international expert in mitral restorative and minimally invasive cardiac surgery, trained at top European institutions and holds memberships in ISMICS and EACTS.

Prof. Giuseppe Speziale specializes in minimally invasive valve surgery and received the "Top Doctors Awards" in 2021. Heart valve replacement may cost around $3,400–$8,500. He serves as National Coordinator of Cardiac Surgery for GVM Care & Research and Director at multiple hospitals. His expertise includes mitral valve repair and aortic surgery. The clinic operates under Italian Health Service accreditation.