The best ozone therapy clinics in Mexico hold JCI and General Health Council accreditations, operating in cities like Puerto Vallarta and Monterrey. According to Bookimed’s ranking, the top clinics are Immunotherapy Regenerative Medicine, Holistic Bio Spa®, and Stem Solutions. They stand out for serving 5,000+ patients annually, 20+ years in regenerative medicine, and teams with biologists and biophysicists. When choosing a provider, look for Consejo de Salubridad General certification, internationally recognized specialists, and extensive protocol experience, with a balance of safety and outcomes. Always consult a qualified ozone therapy specialist before making a decision.