Entrance of Holistic Bio Spa clinic with glass doors and plants

Consultation room at Holistic Bio Spa with exam bed and modern office setup

IV therapy room with recliners and medical monitor at Holistic Bio Spa clinic

Reception area at Holistic Bio Spa with staff and patient waiting lounge in Mexico

Treatment room at Holistic Bio Spa with medical bed and oxygen tanks

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Mexico, Puerto Vallarta

Holistic Bio Spa®

About the clinic

Holistic Bio Spa is an integrative medical center in Puerto Vallarta serving 5,000 patients annually. It combines holistic, regenerative, and alternative medicine with conventional care. Core specialties include integrative oncology and peptide therapy.

10-pass hyperbaric ozone therapy, plasmapheresis, and high-dose vitamin C IV treatments available.
Uses allogenic NK cell therapy and exosome therapy to target cancer cells.
Custom nutritional plans based on DNA testing to strengthen immunity.
Offers red light therapy, cryotherapy, PEMF, HOCATT, and TMS for recovery.
Treats patients from the USA, Canada, Europe, Australia, and Latin America.

Highlights

2004 Year of foundation

4 doctors

2500 patients per year

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Average answering time – 5 minutes

Accepted payment methods

No payment is needed now. You will be charged directly at the clinic when you arrive.
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Treatments prices in the clinic

Last price update — 29.03.2025. Prices can be changed depending on the medical case and doctor's recommendations.

Endocrinology

treatment
Radioiodine therapy	Price on request
Diabetes mellitus treatment with stem cells	Price on request
Thyroidectomy	Price on request
Bioidentical hormone replacement therapy (BHRT)	Price on request

Oncology

treatment
Brachytherapy	Price on request
Hormone therapy	Price on request
Radioiodine therapy	Price on request
Immunotherapy	Price on request
Cryotherapy	Price on request
Brachytherapy for prostate cancer	Price on request
Thyroidectomy	Price on request
Hormone therapy for prostate cancer	Price on request
Cryotherapy for kidney cancer	Price on request

Gastroenterology

treatment
Hormone therapy	Price on request

Dental Treatment

treatment
All-on-4 Dental Implants	Price on request
All-on-6 Dental Implants	Price on request
Porcelain Veneer	Price on request
Tooth Extraction	Price on request
Tooth Whitening	Price on request
Root canal treatment	Price on request
Osteoplasty	Price on request
Braces	Price on request
Veneers	Price on request
Installation of PFM crown	Price on request
Prosthesis of a tooth	Price on request
Treatment of caries	Price on request
Tooth restoration (bonding)	Price on request
Treatment of pulpitis	Price on request
Plastic of gingival recession	Price on request
Sinus-lifting	Price on request
Installation of a dental implant with crown	Price on request
Dental Implant	Price on request
Apicoectomy	Price on request
Crown Lengthening	Price on request
Dental Crown Installation	Price on request
Tooth Reshaping	Price on request
Dental bridge installation	Price on request
Teeth Cleaning (Scaling)	Price on request
Dental Implant with Abutment	Price on request
Gingivectomy	Price on request
Denture	Price on request
All-on-2 Dental Implants	Price on request
Dental cyst removal	Price on request
Nobel Biocare Dental Implants	Price on request
Dental bonding	Price on request
Hollywood Smile	Price on request
Gum surgery	Price on request
Zirconia crown installation	Price on request
Smile makeover	Price on request
Zygomatic All-on-2 implants	Price on request
Flapless All-on-2 implant surgery	Price on request
Zygomatic All-on-4 implants	Price on request
Same day All-on-4 dental implants	Price on request
Zirconia All-on-4 dental implants	Price on request
Zygomatic All-on-6 implants	Price on request
Hybrid All-on-6 implant denture	Price on request
Same day All-on-6 dental implants	Price on request
Endoscopic apicoectomy	Price on request
Temporary anchorage devices (TADs)	Price on request
Twin block braces	Price on request
Onlay bone graft	Price on request
Particulate bone graft	Price on request
Instant veneers	Price on request
Removable veneers	Price on request
Dental crown replacement	Price on request
Esthetic crown lengthening	Price on request
Functional crown lengthening	Price on request
Laser crown lengthening	Price on request
Open flap crown lengthening	Price on request
Same day crown	Price on request
Gold crown	Price on request
Temporary crown	Price on request
Dental bridge for molars	Price on request
Dental bridge prep	Price on request
Porcelain bridge	Price on request
Removable dental bridge	Price on request
Temporary dental bridge	Price on request
Zirconia dental bridge	Price on request
Implant bridge	Price on request
Screw retained implant bridge	Price on request
Endosteal implant	Price on request
Transosteal implant	Price on request
Zygomatic implant	Price on request
Immediate load dental implant	Price on request
Two stage dental implant	Price on request
Tilted implant	Price on request
Surgical extraction of tooth /root	Price on request
Full-Arch Implant-Fixed Complete Dentures in Monolithic Zirconia (6 titanium implants)	Price on request
Full-Arch Implant-Fixed Complete Dentures in Monolithic Zirconia (8 titanium implants)	Price on request
Zirconia veneers	Price on request
Grillz	Price on request
Dental Jewellery	Price on request
Gold Grillz	Price on request
Gemstone Grillz	Price on request
Enamel Grillz	Price on request
Dental prosthetics installation	Price on request

Therapy

treatment
Symptomatic treatment	Price on request
Course of treatment with own stem cells	Price on request
Course of treatment with donor stem cells	Price on request
Drug treatment	Price on request
Ozone therapy	Price on request
Intravenous vitamin C therapy	Price on request
Vitamin infusions	Price on request
Treatment of chronic pain after hernia surgery	Price on request

Diagnostics

treatment
Treatment of chronic pain after hernia surgery	Price on request

Aesthetic Medicine and Cosmetology

treatment
Brow lift	Price on request
Rejuvenation with own stem cells	Price on request
Rejuvenation with donor stem cells	Price on request
Hair mesotherapy	Price on request
PRP Hair Loss Treatment	Price on request
Hyaluronic Acid Threads Lifting	Price on request
Bioidentical hormone replacement therapy (BHRT)	Price on request
Botox for men	Price on request
Botox under eyes	Price on request
Dermabrasion facial	Price on request
Dermabrasion for tattoo removal	Price on request
Diamond dermabrasion	Price on request
Diamond microdermabrasion	Price on request
Hydrafacial dermabrasion	Price on request
Hydro dermabrasion	Price on request
Microdermabrasion	Price on request
Face bump removal	Price on request
Platelet-Rich Plasma (PRP) Therapy	Price on request
Vitamin infusions	Price on request
Exosome therapy	Price on request

Narcology and alcoholism

treatment
Treatment of drug addiction	Price on request

Maxillofacial Surgery

treatment
Mandibular osteotomy	Price on request
Orthognathic surgery	Price on request

Longevity health

treatment
Rejuvenation with own stem cells	Price on request
Rejuvenation with donor stem cells	Price on request
Ozone therapy	Price on request
Intravenous vitamin C therapy	Price on request

Wellness retreats

treatment
Detox retreats	Price on request

Stem Cells

treatment
Stem Cell Therapy	Price on request
Stem cell rejuvenation therapy (anti-aging)	Price on request
Stem cell therapy for knees	Price on request

Clinic Doctors

General practitioner

Eslie Perez

General practitioner

Experience 12 years

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Wellness Specialist

Eduardo Fernandez

Wellness Specialist

Experience 12 years

View

Before & after photos (1)

The results of the procedure are provided by the clinics

Before and after stem cell therapy for knee at Holistic Bio Spa®, improved mobility result

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Licences

COFEPRIS regulatory document for Holistic Bio Spa®, Mexico

Holistic Bio Spa®: more details about the clinic

Mexico, Puerto Vallarta

Holistic Bio Spa® provides a range of alternative cancer treatments designed to complement conventional therapies, focusing on overall well-being and supporting the body's natural healing processes.

Integrative approach to cancer care

The clinic combines conventional medicine with evidence-based complementary therapies, addressing health's physical, emotional, and mental aspects.

Nutritional therapy

Personalized plans – Customized nutrition plans based on DNA testing to strengthen immunity and reduce inflammation.
Detoxification – Programs designed to eliminate toxins and minimize the side effects of conventional treatments.

Ozone therapy

10-pass hyperbaric Ozone therapy – Enhances oxygen levels, supports immune function, and promotes detoxification.
Rectal Ozone insufflation – Improves brain oxygenation and reduces systemic inflammation.

Intravenous (IV) therapies

High-dose vitamin C – Supports immune function, enhances chemotherapy and radiation effects, and reduces inflammation.
Additional IV therapies – These include mistletoe, peptides, antioxidants, and exosomes to aid in recovery.
Plasmapheresis – Removes toxins and heavy metals from the blood to improve overall health.
Allogenic NK cells protocol – Uses donor stem cells to target remaining cancer cells in blood cancer treatments.

Supportive therapies

Hyperbaric oxygen therapy – Accelerates healing and recovery.
Cryotherapy – Supports recovery and is used in certain cancer treatments.
Red light therapy – Reduces inflammation and promotes skin and tissue repair.
Hormone replacement therapy – Balances hormones to enhance energy levels, bone health, and overall well-being.

Mind-body medicine

Stress reduction – Incorporates TMS, meditation, and yoga to support mental well-being.
Emotional support – Provides counseling and therapies to address the emotional challenges of cancer.
Quantum biofeedback – Helps reset brain responses to emotional stressors.

Herbal and botanical medicine

Uses evidence-based supplements to strengthen immunity and promote overall health.

Traditional Chinese medicine (TCM)

Acupuncture – Helps relieve pain and reduce treatment side effects.
TCM therapies – Supports energy balance and immune system function.

Key benefits

Holistic focus – Addresses the whole person, not just the disease.
Personalized care – Treatments are tailored to individual needs and medical history.
Complementary approach – Supports conventional treatments and helps reduce side effects.
Minimally invasive methods – Promotes faster recovery with reduced physical strain.

Additional services

Transfer

Airport to clinic

free

Clinic to airport

free

Language assistance

Available

free

Accommodation

Hotel (apartments) near the clinic, billed daily

Patient reviews

Google 4.8

5 Google reviews

Juan Cisneros

Sep 24, 2025

From the moment I walked in, I felt a sense of calm and renewal. The atmosphere at Holistic Bio Spa is truly peaceful and welcoming, designed to make you feel at ease right away. The staff is incredibly attentive, professional, and genuinely caring, always taking the time to understand individual needs and tailor treatments accordingly. The therapies are a perfect balance of modern techniques and natural healing, leaving me feeling both rejuvenated and deeply relaxed. What I appreciate most is the holistic approach — it’s not just about the body, but also about restoring harmony to mind and spirit.

Ashley Kim

Jun 30, 2025

I can’t say enough good things about Holistic Bio Spa — this place is truly a gem in Puerto Vallarta. From the moment I walked in, I was struck by the prestige and calm of the space — it’s immaculately clean, beautifully designed, and instantly puts you at ease. The staff is incredibly kind, welcoming, and knowledgeable, and the clinic is conveniently located just a short ride from the airport, making it perfect for travelers seeking real healing. What really stood out was the variety of cutting-edge and holistic treatments they offer — everything from ozone therapy and IV drips to acupuncture, cupping, and bee venom therapy. I was fortunate enough to see Dr. Bridget for acupuncture, and I can confidently say she is one of the most gifted healers I’ve encountered anywhere in the world. Her session incorporated electrical stimulation on the needles, cupping, and bee venom therapy, and I felt an immediate lift in my energy and a noticeable relief from anxiety and depression I’ve been carrying. She is intuitive, gentle, and clearly passionate about her craft. I was so impressed that I booked several more appointments during my stay in Puerto Vallarta. If you’re looking for true healing in a supportive and serene environment, this is the place. Highly recommend!

Groovinda Dasi

Jun 5, 2025

A Gem in Puerto Vallarta: Holistic Bio Spa: My great friend David Avocado Wolfe suggested I go to the "Holistic Bio Spa" when he heard I had spike proteins in my blood after a bout of covid last fall. I booked a flight and off I went and I was so very happy I listened to my instincts and went. My experience there was the best ever by far and would recommend this clinic to anyone who is having from serious health issues to just wanting general health support and preventative medicine treatments. The staff is super professional and friendly and made me feel so cared for. Dr. Zoli has attracted the best of the best staff. I went for 2 weeks and had all protocols done from Lasser Plasmapheresis ( filters the blood), Vitamin drips, Ten pass hyperbaric Ozone, Methlyene Blue, Glutathione, Vitamin d3 shots and more +++ I found out thru blood tests that my hormone levels were low and that was dressed immediately and I was sent home to continue the protocol with hormonal peptides. I am back home and integrating my experience. I feel I had the best cleanse ever and then my body was filled with all the goodness from all the drips I had. My energy is much better, my moods have stabalized and I feel revitalized. Highly beneficial! and best of all no spike proteins in my blood! Thank you Dr. Zoli and your super hero team. I also met so many new high vibe friends at the clinic.

Byrnes Vogel

Apr 9, 2025

Since I moved here with my wife Ana, I found the Holistic Bio Spa. It has been a great experience for me. I have neuropathy in my feet and issues with my left shoulder and knee. The therapy that is a available at Holistic Bio Spa is unparalleled. From massage to Cryrogenic Chamber Therapy to Steam Sauna Ozone HOCATT, it is the best medicine for you. The staff is excellent, from the doctors to the receptionists, to the excellent therapists. Just a few names of these great people. Sorry if I don’t name them all. Dr. Zoli, Selene, Megan, Alejandra, Esmeralda, Ramiro, Martin and all the others. Also the people that were there before that have moved on. You can not go wrong to get your health care here. Salud! Byrnes

Calum Coburn

Oct 10, 2025

Update: They fixed their phone number. I had the extreme displeasure of talking with a bot who identified itself as 'Holly'. The bot repeated itself over and over again, and tried to assure me that it was a real human. It was clearly running on a script. I could hear a computer keyboard in the background. What a VERY odd company! Appears to be closed down. They don't answer their Mexican or international phone numbers. Their website chat is a bot, with no way to get to a human. Their contact form gives an error.