The best detox retreat clinics in Mexico hold JCI and General Health Council accreditations, operating in cities like Puerto Vallarta and Playa del Carmen. According to Bookimed’s ranking, the top clinics are Holistic Bio Spa® and Juventa Regenerative Medicine . They stand out for serving 5,000+ international patients yearly and offering therapies like plasmapheresis, exosome therapy, and hyperbaric ozone therapy. When choosing a provider, look for therapies supervised by board-certified specialists, international accreditations, and proven patient satisfaction, with a balance of safety and holistic care. Always consult a qualified detox specialist before making a decision.