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Dr. Corrado Lodigiani has been assistant at the Thrombosis Centre of Humanitas research Hospital from 1998 to 2013 and he became Unit Director in 2013. 

Humanitas Thrombosis Center is a state-of-the-art service for the proper management of the diagnosis and therapy of venous thromboembolic pathology (deep and superficial venous thrombosis, pulmonary thromboembolism, visceral venous thrombosis) and arterial (myocardial infarction, cerebral stroke, peripheral arterial disease). 
Other also rare diseases treated are atypical thrombosis, such as the vascular circulation of the retina, the hearing system and the placental circulation during pregnancy. 

Dr. Lodigiani adopts the multidisciplinary approach and works in collaboration with all medical and surgical specialties. In particular, he carries out clinical and instrumental diagnostics (vascular ecocolordoppler) and research on the causes, diagnosis and therapy of thrombotic and bleeding disorders, congenital and acquired. His clinical activity also involves the diagnosis and management of patients suffering from bleeding diseases, such as haemophilia, von Willebrand’s disease and platelet diseases.

Medical areas of interest:  

In recent years, he has devoted himself with particular interest to the testing, in the role of Principal Investigator in International Clinical Studies, of new antithrombotic drugs and, above all, anticoagulants, which are about to be marketed and will constitute a valid and safe alternative to traditional oral anticoagulant therapy (DOACs). He is also working, with great interest, on researching the causes of idiopathic infertility and the usefulness and effectiveness of some therapeutic strategies, such as the use of anticoagulant drugs, improving the results of artificial insemination procedures. He is the author of numerous articles in international scientific journals and speaker at numerous national and international conferences.

Prof. Andrea Lania has graduated at the Università degli Studi of Milan and is specialized in endocrinology. He is the Unit Director of Endocrinology and Diabetology in Humanitas Research Hospital and his specialization is pituitary diseases, pituitary adenomas, thyroid cancer, pancreatic neuroendocrine tumors, poorly differentiated neuroendocrine carcinomas.

Medical areas of interest:
Pituitary tumors, hypopituitarism, acromegaly, Cushing’s disease and syndrome, neuroendocrine tumors, thyroid and thyroid diseases, adrenal and adrenal diseases, hypogonadism.

Research areas of interest:
Study of the pathogenetic mechanisms of pituitary and neuroendocrine tumors, of the molecular mechanisms responsible for the different response of pituitary and neuroendocrine tumors to medical therapy.

Prof. Lania published 198 peer-reviewed papers (Google Scholar H-Index 47; Scopus H-Index 38, cit tot 4604)

Prof. Lania has a long standing expertise in the field of intra-cellular signaling in endocrine tumors. In particular, in the past ten years, he contributed to analyze the role of PKA regulatory subunits in the pathogenesis and control of cell proliferation of endocrine tumors. Moreover, he contributed to define the role of SSTR5 domains involved in the intracellular trafficking of this receptor in human pituitary cells and to analyze the impact of DR2R and SSTR2&5 polymorphic variants on both the clinical outcome and response to medical treatment in patients with pituitary tumors.

Recently, he contributed to identify the role of cytoskeleton protein FLNA in mediating both intracellular signaling and membrane targeting of somatostatin type 2 receptor and D2R in pituitary and pancreatic neuroendocrine tumors. Finally, he contributed to explore the intracellular mechanisms possibly involved in mediating the interplay between drugs commonly used in the treatment of neuroendocrine tumors.

Previous experience:
2005-2008 Fondazione Ospedale Maggiore Policlinico IRCCS, Milan, Italy
Director of Endocrinologic Day Hospital and surgery on pituitary disorders. 

Publications: https://www.ncbi.nlm.nih.gov/pubmed?term=lania%20A 

Prof. Stefano Respizzi is the Head of the Rehabilitation and Functional Recovery Unit in Humanitas Research Hospital. He is specialized in orthopaedic rehabilitation and sport rehabilitation. In 1986, with some colleagues, he founded the Sports Medical Centre of Sesto San Giovanni. In 1988 he founded the GISMI (Italian Group of Study of Isokinetic Method), where he is also an advisor. 

Medical areas of interest: orthopaedic rehabilitation, traumatology and sports rehabilitation, sports medicine, physical therapy

Research areas of interest: orthopaedic rehabilitation, sports medicine, orthopaedics

Previous experience:  

• 1991-1996 Orthopaedic Institute of Gaetano Pini, Italy
  Assistant Physiatrist
• 1991-1991 Hospital of the Piemonte region , Italy
  Specialist doctor in sports medicine
   

In 1986, with some colleagues from Milan, he founded the Centro Medico Sportivo of Sesto San Giovanni, a facility recognized by Lombardia Region and dedicated to the release of certificates of fitness for practicing competitive sports.

He has been a consultant for the Italian Volleyball Federation.
In 1988 he founded GISMI (Gruppo Italiano Studio Metodiche Isokinetiche).
In 2002 he became managing director of Isokinetic Milano, one of the centers of the network of Isokinetic Sports Rehabilitation Centers.

Prof. Romano Lutman is the Head Oncological and interventional radiology Unit.

Medical areas of interest: 
diagnostic and interventional oncology, in particular linked to percutaneous imaging-guided procedures.
He has performed over 3000 CT guided lung biopsies and numerous international trials on anticancer drugs.

Research areas of interest: 
advanced oncological diagnostics. Percutaneous minimally invasive imaging-guided diagnostic and therapeutic procedures in oncology.

Previous experience:  
- 1991-1996 Orthopaedic Institute of Gaetano Pini, Italy
Assistant Physiatrist
- 1991-1991 Hospital of the Piemonte region , Italy
Specialist doctor in sports medicine

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=lutman r

Dr. Paolo Omodei is the Unit Director of the Autonomous section of Clinical Gastroenterology.

He graduated with honors in the academic year 1988-89 at the Università degli studi of Milan. He specialized in Gastroenterology and Digestive Endoscopy in 1994. Winner of the competition for PhD in Research in Clinical Methodology in the academic year 1994-95. In 1996 he won the public competition for Assistant at the Gastroenterology Service of the Niguarda Ca' Granda Hospital in Milan. He held this post until June 1997. From 1997 to 1999 he held the position of Assistant at the Gastroenterology and Digestive Endoscopy Unit of Humanitas Clinical Institute, directed by prof. Alberto Malesci. From 2000 to 2006, he held the position of Assistant of the Gastroenterology and Digestive Endoscopy Unit of the Humanitas Clinical Institute. Since 2006 he has been Head of the Section of Emergency Gastroenterology and Head of Gastroenterology at the Humanitas Clinical Institute. He is Professor of Medicine and Surgery at the University of Milan.

1996-1997 Hospital of Niguarda, Milan, Italy
Assistant in the Gastroenterology and Digestive Endoscopy Services directed by Prof. Raffaele Arcidiacono

1987-1996 Polyclinic Hospital, Milan, Italy
Specialising in Gastroenterology in the Gastroenterology and Digestive Endoscopy service of the Institute of Internal Medicine directed by Prof. Nicola Dioguardi.
Volunteer medical specialist in the Gastroenterology and Digestive Endoscopy service in the Institute of Internal Medicine directed by Prof. Nicola Dioguardi.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=Omodei P

Dr. Paola Maria Magnoni has graduated in general medicine and radiodiagnostics at Università degli Studi of Milan and is the Ultrasound Unit Director of Humanitas Research Hospital, where she dedicates especial attention to internal, oncological, breast, endocrinology and loop ultrasound, performing over 5000 examinations of which 500 needle biopsy annually.

Medical areas of interest: Ultrasound in all its fields of use, especially:

Diagnostic ultrasound: internal, oncological, intestinal loops, endocrinology.

Interventional ultrasound: superficial needle biopsies of areas such as breast, thyroid, soft parts; and deep needle biopsies of areas such as abdominal organs, liver, kidney pancreas; retroperitoneum; paracentesis, thoracentesis, drainage and inflections.

Research areas of interest: sarcomas, early diagnosis in oncological pathologies, iconographic study of IBD, senology, endocrinology.

Dr. Nunzio Paolo Nuzzi has graduated at Università Cattolica del Sacro Cuore (Milan) and carried out his specialisation in neuroradiology. He is the Unit director of Interventional radiology at Humanitas Research Hospital.

Medical areas of interest: interventional neuroradiology, cerebrovascular diseases, ischemic and haemorrhagic stroke, brain aneurysms, brain and spinal arteriovenous malformations and arterial-venous fistulas (AVF), intracranial stenosis and neck stenosis.

Research areas of interest: new biomedical devices for the treatment of cerebrovascular diseases. Clinical research on minimally invasive endovascular procedures.

Prof. Marco Montorsi is the Director of the Department of General and digestive surgery unit in Humanitas Research Hospital and he is Professor of General Surgery at the Humanitas University. His academic career started in the the Humanitas University of Milan, where he entered in 1980 as Assistant Professor and was appointed as Professor of Surgery in 2001.

His main interests are in the field of digestive diseases and in the surgical treatment of the related pathologies, mainly hepatico-pancreatico-biliary (HPB) and colorectal pathologies. He is indeed the Director of the Department of Surgery in Humanitas Research Hospital where a great volume of major abdominal surgeries is routinely performed. Around 250 -300 hepatic and pancreatic resections and 350 colorectal resections.
He began performing laparoscopic colorectal surgery in the early 90s and gained a lot of experience in this field. The vast majority of colorectal tumours diagnosed in the department of Surgery is submitted to laparoscopic resection thus allowing a smooth and safe disease course. A robotic approach with the new Da Vinci equipment is now available for patients with rectal tumours.

Transanal endoscopic microsurgery (TEM) with dedicated instruments is also offered to selected patient with low-sited rectal tumours so sparing major abdominal approach.

A routine policy of strict interaction with the Dept. of Oncology is active for patients needing a perioperative chemo- and radiotherapy with the aim of full integration for a better care and results.

Prof. Marco Montorsi is also Humanitas University President with over 10 years of experience in didactic and clinic teaching to medical students.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=montorsi+marco

Dr. Lucia Torracca is leading the Cardiac Surgery Unit at Humanitas Research Hospital. She received her training at Ospedali Civili di Brescia and at Ospedale San Raffaele with Professor Ottavio Alfieri, were she improved her knowledge in the mitral disease focusing in the reparative and preservative approaches. At the same institution she led the minimal invasive and robotic division before moving to Ospedali Riuniti Di Ancona to be chief of the Cardiac Surgery Complex Unit. Dr. Torracca has performed more than 55 hundred cardiac surgeries. Thanks to her surgical and academic curriculum, she has been an active member of the steering committee of the European Society editing Guidelines for the treatment of heart diseases.

Together with her team in Humanitas, she can approach every cardiac disease affecting adults, especially focusing on the minimal invasive approach to reparative valve disease. State of the art technologies are regularly explored and implemented in the Open Heart dedicated Operating Room and Intensive Care Unit to ensure best outcomes, shorter hospital stay and fewer surgical complications.

The surgical expertise of Dr. Torracca go from open heart circulatory-arrest procedure to off-pump and/or trans-catheter procedures (MitraClip or TransApical Aortic Valve Implants).

Dr. Torracca and her team can claim the highest rate of mitral valve repair in Bi-leaflet prolapse (Barlow Disease) hitting almost 99% of conservative approach in minimal invasiveness at the time of surgery, maintaining >95% success rate at long term follow up: this option is further advantageous in the youngest patient population allowing restrain from anticoagulation therapy and perfectly normal quality of life.

Author or co-author of 151 publications in national and international scientific journals.

Prof. Leonardo Maradei is specialised in orthopaedics and traumatology and is the Director of the Foot Surgery and Minimally Invasive Operations Unit in Humanitas Research Hospital. 

Prof. Leonardo Maradei performs surgery on the foot with minimally invasive techniques and arthroscopic surgery. After his specialization he deepened his studies in arthroscopic surgery of the shoulder and the knee at the Mississippi Sports Medicine & Orthopaedic Center (USA), under the guidance of prof. F. H. Savoie. He has developed considerable experience in shoulder prosthetic surgery as a pupil of prof. Mario Randelli. 
His research is focused on the development of new prosthetic materials for the shoulder. During his years in Humanitas he has performed more than 2000 surgeries on the foot, more than 1000 on the knee and more than a 1000 on the shoulder. 

Dr. Maradei is a professor at Università Statale of Milan where he teaches Medicine and Surgery - Lessons on minimally invasive surgery of the shoulder and knee.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=maradei+leonardo

Dott. Antonio Frontera is the Electrophysiology Unit Director in Humanitas Research Hospital.  

Medical areas of interest: 

After graduating in Medicine and Surgery at the University Cattolica del Sacro Cuore in Rome in 2006, he specialized in Cardiology at the same university in 2012.

Soon after his specialization he moved to England where he was hired as a Clinical and Research Fellow in cardiac electrophysiology at the Bristol Heart Institute (NHS), Bristol. 
He won a scholarship from the European Society of Aritmology (EHRA) and completed his training in cardiac electrophysiology at the prestigious Haut Léveque Hospital in Bordeaux, France, directed by Prof. Michel Haïssaguerre. In the same French university, he obtained his PhD.

During these 5 years of training abroad, he performed about 800 trans catheter ablation surgeries focusing mainly on the treatment of supraventricular arrhythmias. As a researcher, he has published nearly 100 scientific papers on innovation and trans catheter ablation techniques, defibrillator and pacemaker functioning algorithms.

Back to Italy, he was employed at the Aritmology Unit of the San Raffale Hospital specializing in the treatment of ventricular tachycardia, performing more than 150 procedures as a first and second operator.

To date, Dr. Frontera is the author of more than 145 scientific papers published in international journals. He constantly participates in national and international congresses of the sector.

Research areas of interest:
He has particular interest in the analysis of endocavitary signals (EGMs) in ventricular tachycardia and atrial fibrillation.

Thanks to a close collaboration with the Mathematics department of Politecnico di Milano, directed by Prof. Quarteroni, he studied innovative techniques for the treatment of complex arrhythmias.

Previous experience:
 

• Clinical and Research Fellow in Cardiac Electrophysiology - Bristol Heart Institute, Bristol, UK
• Clinical and Research Fellow in Cardiac Electrophysiology - Hôpital Haut Léveque, Bordeaux, FR

Publications: 

Sinus node exit, crista terminalis conduction, interatrial connection and wavefront collision: key features of human atrial activation in sinus rhythm.
Pambrun T, Derval N, Duchateau J, Ramirez FD, Chauvel R, Tixier R, Marchand H, Bouyer B, Welte N, André C, Nakashima T, Nakatani Y, Kamakura T, Takagi T, Krisai P, Ascione C, Balbo C, Cheniti G, Vlachos K, Bourier F, Takigawa M, Kitamura T, Frontera A, Meo M, Denis A, Sacher F, Hocini M, Jaïs P, Haïssaguerre M.Heart Rhythm. 2022 Jan 13

Electrogram fractionation during sinus rhythm occurs in normal voltage atrial tissue in patients with atrial fibrillation.
Frontera A, Limite LR, Pagani S, Cireddu M, Vlachos K, Martin C, Takigawa M, Kitamura T, Bourier F, Cheniti G, Pambrun T, Sacher F, Derval N, Hocini M, Quarteroni A, Della Bella P, Haissaguerre M, Jaïs P.Pacing Clin Electrophysiol. 2021

Slow Conduction Corridors and Pivot Sites Characterize the Electrical Remodeling in Atrial Fibrillation - ScienceDirect
Antonio Frontera MD, Ph.D1, Stefano Pagani Ph.D2, Luca Rosario Limite MD1, Andrea Peirone MD1, Francesco Fioravanti MD1, Bogdan Enache MD6, Jose Cuellar, MD4, Konstantinos Vlachos, MD5, Christian Meyer, MD, MA7, Giovanni Montesano, MD8, Andrea Manzoni, Ph.D2, Luca Dedè2 Ph.D2, Alfio Quarteroni, Ph.D2,3, Decebal Gabriel Lațcu, MD6, Pietro Rossi MD, Ph.D9, Paolo Della Bella MD1.
JACC EP Jan 2022

Right ventricular outflow tract electroanatomical abnormalities in asymptomatic and high-risk symptomatic patients with Brugada syndrome: Evidence for a new risk stratification tool?
Letsas KP, Vlachos K, Conte G, Efremidis M, Nakashima T, Duchateau J, Bazoukis G, Frontera A, Mililis P, Tse G, Cheniti G, Takigawa M, Pambrun T, Prappa E, Sacher F, Derval N, Sideris A, Auricchio A, Jais P, Haissaguerre M, Hocini M.J Cardiovasc Electrophysiol. 2021

Effect of electrode size and spacing on electrograms: Optimized electrode configuration for near-field electrogram characterization.
Takigawa M, Kitamura T, Basu S, Bartal M, Martin CA, Martin R, Cheniti G, Vlachos K, Pillois X, Frontera A, Massoullié G, Thompson N, Bourier F, Lam A, Duchateau J, Pambrun T, Denis A, Derval N, Cochet H, Haïssaguerre M, Sacher F, Hocini M, Jaïs P.Heart Rhythm. 2022 Jan;

Prof. Antonio Costanzo is the Dermatology Unit Director in Humanitas Research Hospital. He graduated with his MD degree in Medicine and Surgery from the University of Rome, La Sapienza in 1994. He then went on to complete post-graduate study and received a speciality degree in Internal Medicine in 1999 and a Dermatology speciality degree in 2006.

Medical areas of interest:

• Inflammatory and autoimmune skin diseases (Psoriasis, Atopic Dermatitis, Alopecia Areata, Chronic Urticaria, Suppurative Hydroadenitis, Scleroderma, Lupus)
• Personalized Medicine, Biological Psoriasis Therapy
• Dermatological Oncology (Melanoma, Actinic Keratosis, Basocellular and Spinocellular Epitheliomas).
• Prevention of skin neoplasms (dermatoscopy, computer mapping of moles).
• Dermatological surgery

Previous experience:

• Director of Dermatology Unit at Sant’Andrea Hospital in Vercelli
• University Researcher/Hospital Assistant at Tor Vergata Hospital 

Research areas of interest: 

• Psoriasis pathogenesis of other inflammatory and autoimmune skin diseases
• Pathogenesis of skin neoplasms
• Genetic disorders of the skin

His clinical research is focused on the characterization of the activity of biologics in psoriasis and psoriatic arthritis. This research is strictly linked to basic research activity on the pathogenesis of psoriasis and on the use of pharmacogenetic approach to predict the efficacy and safety of biologics in psoriasis.

In the past, Professor Costanzo has collaborated to the characterization of basic mechanisms of TNF inflammatory signalling in epithelial cells and NFkappaB regulation by different stimuli. More recently his research group has collaborated to the discovery of IL-21 as critical mediator of keratinocyte proliferation in psoriasis. Professor Costanzo has authored or co-authored more than 120 publications in internationally peer-reviewed journals.

Teaching experience: Full Professor of Dermatology at Humanitas University

Publications: https://www.ncbi.nlm.nih.gov/pubmed/?term=Costanzo+A 

Prof. Alessio Michele Goffredo Aghemo is the Hepatology Unit Director in Humanitas research Hospital.

Medical areas of interest: 

• liver diseases
• viral hepatitis
• metabolic hepatitis
• liver cirrhosis

Previous experience: 

From 2007 to 2017 he was the 1st level Medical Director at the U.O of Gastroenterology of the IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico, Milan.

Research areas of interest: 

Clinical and research activity focused on natural history and treatment of viral hepatitis.

He is the author of 155 peer-reviewed publications (Impact Factor total 1151.3, H-Index 25 according to Scopus, H-Index 20 last 5 years Scopus, H-Index 30 according to Google Scholar) (updated September 2017).

From 2013 to 2016 he was a scientific member of the governing board of the European Association for the Study of the Liver (EASL).

Since 2016 he is a member of the scientific committee of the European Association of Gastroenterology (UEG).

He is a member of the AISF (Italian Association for the Study of the Liver) commission for antiviral drugs directed against HCV (2012-present). Since 2016 he has been the coordinator of the same. 

He was AIFA/EMEA expert for liver disease since 2008.

Member of the Executive Committee of the HCV Regional Network, determined by the Lombardy Region on 28 September 2015.

He participated as an expert in the drafting of the European Guidelines 2013-2014-2015-2016-2017 (EASL) and Italian (AISF) on the Treatment of Chronic Hepatitis C.

Teaching experience:

He is associated professor of Gastroenterology at Humanitas University since September 2017.