Best Sensorineural hearing loss doctors: TOP 95 doctors

Name: Mehmet Palali

Place and year of birth:

Manisa, 11.01.1984

Education:

Istanbul university Cerrahpasa Medicine Faculty 2001-2007 

Specialization: Ankara Numene Science and Research Hospital – ENT clinic – 2008-2013

Experiences:

Yozgat State Hospital: 2013-2016

Canakkale Biga Devlet Hospital : 2016-2017

Medlife Bagcilar Hospital -2017-2018

Erdem Hospital- 2018- present

Professional Interests

Rhinoplasty 

Revision rhinoplasty

Otoplasty

Clinic Attended as a Researcher 

 1) Investigation of SCGB3A1 (UGRP2) gene arrays in patients with nasal polyposis. 

Palalı M, Murat Özcan K, Ozdaş S, Köseoğlu S, Ozdaş T, Erbek SS, Yıldırım E, Ensari S, Dere H. 

Eur Arch Otorhinolaryngol. 2014 Dec;271(12):3209-14. 

2) Prognostic effect of hyperbaric oxygen therapy starting time for sudden sensorineural hearing loss. 

Yıldırım E, Murat Özcan K, Palalı M, Cetin MA, Ensari S, Dere H. 

Eur Arch Otorhinolaryngol. 2015 Jan;272(1):23-8. 

3) Endoskopik Dakriyosistorinostomide Başarısızlık Nedenleri 

Mehmet Ali ÇETİN, Kürşat Murat ÖZCAN, Aykut İKİNCİOĞULLARI, Sabri KÖSEOĞLU, Mehmet PALALI, Serdar ENSARİ, Hüseyin DERE 

Ortadoğu Tıp Dergisi 5 (1): 29-32 2013 

4) Cervical lymphadenopathy: progressive transformation of germinal centers 

İkincioğulları A, Köseoğlu S, Çetin MA, Palalı M, Ensari S, Kayaçetin S, Kulaçoğlu S, Dere H. 

Kulak Burun Bogaz Ihtis Derg. 2013 Sep-Oct;23(5):307-11. 

5) Papiller Onkositik Kistadenom: Olgu Sunumu Mehmet Palalı, Aykut İkincioğulları, Sabri Köseoğlu, Doğan Atan, Erol Yıldırım, Hüseyin Dere 

34. Türk Ulusal Kulak Burun Boğaz ve Baş Boyun Cerrahisi Kongresi P-377 

6) Temporal Kemik Karsinomu İle Birlikte İnverted Papillom Zemininde Gelişen İntranazal Karsinom: Olgu Sunumu 

35. Türk Ulusal Kulak Burun Boğaz ve Baş Boyun Cerrahisi Kongresi PS3-073 

Hüseyin Dere, Mehmet Ali Çetin, Emre Apaydın, Erol Yıldırım, Mehmet Palalı, Aykut İkincioğulları 

7) Burun Tıkanıklığının Nadir Bir Nedeni: Alt Konka Bülloza 

Hakan Dağıstan, Mehmet Palalı 

37. Türk Ulusal Kulak Burun Boğaz ve Baş Boyun Cerrahisi Kongresi EP-124

Certifications:

Hobbies

Play classical guitar

Draw cartoon

Any other educational courses and certificate (those conducted internationally as well):

1. Otorhinolaryngology Allergy Course 2004

2. Occupational English Test OET certificate 2016

3. Ege university Cadaver DBsection Course 2017

Memberships & Associations (Please list all your local, regional and international memberships

Education:

From 2007 to 2013, she studied at Azerbaijan Medical University, Faculty of General Medicine.

From 2014 to 2018, she completed her residency in Otorhinolaryngology at Baku Health Center.

Courses and Trainings:

2019: Completed a course at the Azerbaijan State Institute for the Advanced Training of Doctors named after A. Aliyev.

2022: Participated in the “Emre İlhan Clinic” Fellowship Program in Istanbul, Turkey.

2023: Attended the “All in One Rhinoplasty Congress 8” in Istanbul, Turkey.

2023: Participated in the “17th National Facial Plastic Surgery Congress” in Izmir, Turkey.

2023: Attended the Azerbaijan Rhinologists' International Congress in Baku, Azerbaijan.

2024: Participated in the “All in One Rhinoplasty Congress 9” in Istanbul, Turkey.

2024: Attended the Baku Rhinoplasty Masterclass in Baku, Azerbaijan.

Work Experience:

In 2018, worked as an ENT specialist at Baku Health Center.

Since 2018, has been working as an ENT specialist at Polyclinic No. 20.

Since 2021, has been working as an ENT specialist at Premium Clinic.

Memberships:

Member of the Board of the Azerbaijan Society of Otorhinolaryngology

Member of the Azerbaijan Association of Rhinoplasty Surgeons

Dr. Turgay Toğçuoğlu, with 20 years of experience, has performed many successful surgeries in the field of otolaryngology. He has performed many surgeries on Rhinoplasty

Op. Dr. Ertugrul Kibar

Specialization : Ear Nose Throat

Foreign Language : English

Education :

Medicine:

2011 Abant İzzet Baysal University Faculty of Medicine

Expertise:

2016 Selcuk University Faculty of Medicine – ENT AD.

Thesis:

Evaluation of upper esophageal sphincter pressure in patients with vocal cord pathology

Certificate of competency:

He has The Turkish Board Of Otorihnolaryngologj- Head and Neck Surgery Qualification Certificate.

Experience:

Medical interests and specialties:

Nose aesthetics (Ultrasonic Rhinoplasty)

Endoscopic (closed method) Hearing and Eardrum Surgery

Pediatric ENT Diseases

Snoring Treatment and Surgery

Head and Neck Tumors

Vertigo (Dizziness), Tinnitus (Tinnitus)

Voice and Swallowing Problems

Experience:

2012-2016 Selcuk University ENT Clinic

2016-2019 Konya Training and Research Hospital ENT Clinic

2019-2020 Yalova State Hospital ENT Clinic

2020- 2022 Special Specialists Yalova Hospital

2022- …… Private Sakarya Adatip Hospital

Memberships:

1- Turkish Otorhinolaryngology Head and Neck Surgery Association

2- European Association of Young ENT Physicians

 3- Turkish Medical Association

Article, Presentation, Publication, Congress, Course, Award:

Works:

1- Attention deficit hyperactivity disorder symptoms in children with vocal fold nodules

O Erdur, A Herguner, K Ozturk, E Kibar, C Elsurer, MK Bozkurt, International journal of pediatric otorhinolaryngology 85, 5-7

2- Aberrant internal carotid artery: a rare cause of dysphagia

K Ozturk, O Erdur, E Kibar, F SofuogluJournal of Craniofacial Surgery 27 (3), 818

3- Evaluation of upper esophageal sphincter in benign vocal lesions

E Kibar, O Erdur, K Ozturk European Archives of Oto-Rhino-Laryngology 275 (12), 3033-3037

4- Permanent quadriplegia following replacement of voice prosthesis

K Ozturk, O Erdur, E Kibar Journal of Craniofacial Surgery 27 (8), e741-e743

5- Analysis of cases with otosclerosis

B Çolpan, K Öztürk, Ç Elsurer, E Kibar, Ö Erdur Journal of Otorhinolaryngology 4 (3), 105-10

6- Hydatid Cyst of the Parotid Gland: A Rare Location

O Erdur, B Colpan, F Sofuoglu, E Kibar Journal of Craniofacial Surgery 29 (1), e98-e99

7- Paediatric mandibular fractures: A retrospective study of 15 patients

E Demir, O Erdur, E Kibar, C Elsurer, MK Bozkurt, K ​​Ozturk, B Colpan

British Journal of Oral and Maxillofacial Surgery 54 (10), e113-e114

8- Giant concha bullosa causing severe nasal congestion

Ö Erdur, Ç Elsurer, E Kibar, MK Bozkurt ENT Applications 35 (ENT Applications)

9- Endoscopic excision of recurrent nasal septal pyogenic granuloma

Contemporary Elsurer, Omer Erdur, Hakan Dagestan, Mete Kaan Bozkurt, Ertugrul Kibar

ENT Applications 81 (2016;4(2):81-84)

10- Cervical vertebra osteophytes causing dysphagia: two case reports.

Z Fazliogullari, A Nayman, E Kibar, H Karabagli, K Ozturk, AK Karabulut

Anatomy: International Journal of Experimental & Clinical Anatomy

11- Giant pleomorphic adenoma of parapharyngeal space extending to the skull base

E Kibar, B Colpan, F Sofiev

Op.Dr. İbrahim Altoparlak was born in 1977 in Erzurum.

He started his medical education at Ankara University Faculty of Medicine in 1995 and completed it in 2001. In 2001, he started his specialization training at Ankara University Faculty of Medicine, Ear Nose and Throat Clinic, and completed his specialization in 2006. Between 2006 and 2009, he improved himself in Head and Neck Tumor Surgery and Aesthetic Nose Operations in Ankara Oncology Hospital, Ear Nose and Throat Training Clinic. He has awarded papers at scientific meetings and articles published in scientific journals. Between 2010 and 2018, he worked as a physician at Istanbul Private Doğan Hospital and Private Service Hospital. He has been working in his own practice as of October 2018. In addition, since 2021, 

Dr.Altoparlak continues his operations with the Aesthepan clinic. Dr.Altoparlak performs at least 2 or 3 aesthetic operations a day, and he has hundreds of successful surgeries.

Dr. Hakan Akçin is an experienced Otorhinolaryngology (ENT) specialist. He has worked in the field for over 35 years and graduated from Ankara University Faculty of Medicine in 1988. He is known for treating allergic rhinitis and has achieved strong results with immunotherapy and phototherapy.

Dr. Akçin is skilled in functional endoscopic sinus surgery and rhinoplasty. He focuses on both function and appearance in his procedures. He has performed many successful surgeries and advanced treatments. His thorough approach to patient care in ENT has earned him wide recognition.

Prof. Dr. Fehmi Döner is an experienced Ear, Nose, and Throat (ENT) specialist with more than 20 years in clinical practice. He graduated from Istanbul University Cerrahpaşa Faculty of Medicine. He completed his specialty training at Erzurum Atatürk University Faculty of Medicine.

Dr. Döner earned the titles of associate professor and professor at Süleyman Demirel University in Isparta. These titles reflect his expertise and academic achievements. He now works at Istanbul Medical Park Bahçelievler Hospital. He is recognized for his advanced ENT procedures and strong commitment to patient care.

OP.DR.Paşa Dağıstanlı

experıence

Educatıon and Traınıng

skılls

Prof. Dr. Ali Vefa YÜCETÜRK was born in Aydın in 1963. He graduated from Hakimiyetimilliye Primary School in 1974, Izmir Private Turkish High School in 1980, and graduated from Ege University Faculty of Medicine in 1986.

After completing his compulsory service at Adıyaman's Çelikhan District Health Center in 1986-89, he specialized in Ear Nose and Throat Diseases at Karadeniz Technical University Faculty of Medicine between 1989-92 and worked in the same clinic as a specialist until 1994. KKK in 1993. He did his military service at Izmir Military Hospital.

He started working as an ENT faculty member at Celal Bayar University Faculty of Medicine in 1994, and became an associate professor in 1999 and a professor in 2005.

In 1996, he carried out studies and research on larynx and parotid surgery at the ENT Clinic of the University of Ferrara, Italy, with Prof. Dr. Carlo Calearo and Prof. Dr. Antonio Pastore.

He is a member of the Turkish Otorhinolaryngology and Head and Neck Surgery Association and the Laryngology Association.

He supervised four theses on laryngeal cancer, inner ear hearing loss and snoring-sleep apnea.

He participated in more than 40 congresses, courses and meetings at home and abroad as a speaker and participant.

He has 18 scientific articles published in international and 31 national journals, 11 international and 35 papers presented in national meetings, and 5 copyrighted book chapters. In particular, his studies on snoring, obstructive sleep apnea, voice diseases, laryngeal cancer and ear microsurgery have been at the forefront.

Dr. Enis Ekincioglu is a skilled plastic surgeon and ENT specialist. He focuses on cosmetic facial procedures and head and neck surgery. He received 2nd prize at the 40th National ENT Congress. This award recognizes his clinical skills and research.

Dr. Ekincioglu has published many articles in respected national and international journals. His work has helped advance his field. He is a member of the Turkish Otorhinolaryngology Head and Neck Surgery Society, the European Rhinologic Society, and the American Rhinologic Society.

2022.05 – Current

EAR NOSE AND THROAT SPECİALİST; Asyaeastetic, ıstanbul/turkey

2019.09 – 2022.05

ear nose and throat specialist, özel abat tıp merkezi 

ıstanbul/turkey

2017.09 –2019.09 

ear nose and throat specialist; Necmi Kadıoğlu devlet hastanesi, ISTANBUL/TURKEY

EAR

– Serous otitis and ear tube

– Ear calcification, otosclerosis and spadetomy and teflon piston application

– Chronic middle ear infections and various tympanoplasty surgeries

-Perforated eardrum and surgery

-Cochlear implant

NOSE

-Bone curvature or septoplasty surgery

-RHINOPLASTY SURGERY

-Nose aesthetics

-Sinusitis and surgeries

-Nasal polyps and surgery

-Concha

-Endoscopic operation of tear duct obstruction

Dr. Ender Şahin was born in Kırşehir, Turkey in 1981. He embarked on his journey in the field of medicine at an early age and went on to achieve great heights in his career as a prominent ear, nose, and throat specialist.

In 2007, Dr. Şahin successfully graduated from Hacettepe University Medical Faculty, marking the beginning of his illustrious medical career. His dedication to the field led him to pursue specialization at Ankara Education and Research Hospital in the same year. During his specialized training, he became actively involved in cadaver studies, focusing particularly on the areas of facial plastic and ear surgery.

Dr. Şahin’s commitment to advancing his field is reflected in his membership in prestigious medical associations, including the Turkish Society of Otorhinolaryngology-Head and Neck Surgery (Turkish KBB Society), the Facial Plastic Surgery Association, and the Turkish Medical Association (Türk Tabipleri Birliği).

He now practices at his own private clinic, where he specializes in a wide range of medical procedures, including genioplasty, tonsillectomies, correction of deviated septums, rhinoplasty, ear drum reconstruction, otoplasty (pinning back protruding ears), snoring surgery, endoscopic sinus surgery, endoscopic tear duct surgery, and vocal cord nodule and polyp removal surgeries.

His particular areas of interest include:

• Adenoid (adenoidectomy)
• Otitis Media (middle ear infection)
• Nasal Tumors (tumor removal and reconstruction)

Dr. Ender Şahin’s passion for improving the quality of life for his patients and his dedication to advancing medical knowledge make him a respected figure in the field of otolaryngology. His commitment to the well-being of his patients and his contributions to the medical community continue to leave a lasting impact on the world of medicine.

CURRICULUM VITAE

VOLKERT B. WREESMANN MD PhD

Consultant Otolaryngologist

Oncologic Head and Neck Surgeon

Thyroid and Parathyroid Surgeon

Facial Plastic Surgeon

Principal Positions

• Centro Medico Teknon, Barcelona, Spain

Chairman, Department of Otolaryngology-Head and Neck Surgery

July 1st 2024 – present

• Juaneda, Ciutadella Menorca, Spain

Consultant Otolaryngologist-Head and Neck Surgeon

January 2025 – present

• Avantmedic, Lleida, Spain

Consultant Otolaryngologist-Head and Neck Surgeon

July 1st 2024 – present

• Clinica Omega Zeta, Andorra

Consultant Otolaryngologist-Head and Neck Surgeon

March 1st 2022 – present

• University Hospitals Dorset NHS Foundation Trust

Consultant Otolaryngologist-Head and Neck Surgeon

August 1st 2021 – October 1st 2023

• Oxford University Hospitals NHS Foundation Trust

Honorary Consultant Otolaryngologist-Head and Neck Surgeon

May 1st 2021 – April 30th 2024

• Portsmouth Hospitals University NHS Trust, Portsmouth, UK

Consultant Otolaryngologist-Head and Neck Surgeon

July 18th 2016 – April 30th 2021

• Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK

Consultant Otolaryngologist-Head and Neck Surgeon

November 7th 2015 – May 31st 2016

• Heart of England NHS Trust, Birmingham, UK

Consultant Otolaryngologist-Head and Neck Surgeon

March 1st 2015 – October 31st 2015

• University Medical Center Utrecht, Netherlands

Consultant Otolaryngologist-Head and Neck Surgeon

November 1st 2013 – June 1st 2014

Memberships

• American Head and Neck Society – Member

Netherlands Academy of Otolaryngology - Member

Professional Licences

• United Kingdom

GMC Certification

Fully Registered Medical Practitioner with Specialist Registration with a License to Practice

Registered: 02/02/2015

GMC # 7499626

• United States of America

New York State Department of Health

New York State Education Department

Registered: July 2011

License# P80949

Physician

• Netherlands

Dutch Ministry of Health (BIG Registration)

BIG Registered: 22-06-2005

BIG #19063373601

Physician

Dutch Specialist Board (RGS)

RGS registered: 01-02-2011

RGS #1911979

Otolaryngology-Head and Neck Surgeon

• Spain

Collegi de Metges de Barcelona

COMB: 63638

• Andorra

Collegi de Metges d’Andorra

RPS: 03098

COMA: 876

Education

• Memorial Sloan-Kettering Cancer Center

Surgical Fellowship, Head and Neck Surgery

New York, New York, USA

August 1st 2011 - July 31st 2013

600 bed dedicated cancer center

Performed 1200 major oncologic head and neck resections in 2 years

• United States of America ECFMG Certification

United States Medical Licensing Examination (USMLE)

Certification: June 22nd, 2010

Scores: 

   Step I: 244/99 

   Step IIa-Clinical knowledge: 227/94

   Step IIb-Clinical Skills: PASSED

   Step III: 206/85

• Netherlands Cancer Institute

Surgical Fellowship, Head and Neck Surgery

Amsterdam, The Netherlands

February 1st 2011 - July 31st 2011

Specialized Head and Neck Cancer Surgery Department

200 bed hospital

• Amsterdam University Medical Center/Netherlands Cancer Institute

Residency Training, Otolaryngology-Head and Neck Surgery

Amsterdam, the Netherlands

February 1st 2006 – January 31st 2011

• University of Amsterdam School of Medicine

Medical Doctor (MD)

Amsterdam, the Netherlands

December 2002 - January 28th 2005

• University of Amsterdam

Doctor of Philosophy (PhD), Molecular Biology

Amsterdam, the Netherlands

Thesis title: Molecular-cytogenetic characterization of head and neck cancer

December 2nd, 2004

• Erasmus University School of Medicine

Doctoral Degree in Medicine

Rotterdam, the Netherlands

September 1994 - November 17th, 1998

Research Training

• Memorial Sloan-Kettering Cancer Center

Laboratory of Epithelial Cancer Biology, Head and Neck Service, Department of Surgery, New York, New York, USA

Research Fellowship in Molecular Oncology

Supervisors: Dr. Bhuvanesh Singh MD, PhD and Dr. Jatin P. Shah, MD, FACS

March 1st 1999 - September 30st 2002

• University of California San Francisco (UCSF)

Department of Otolaryngology-Head and Neck Surgery, San Francisco, California, USA

Post-doctoral Research Fellowship in Head and Neck Oncology

Supervisors: Dr. Steven Wang MD And Prof David Eisele MD

February 2005 - January 2006

Academic Activities

University of Amsterdam

Doctorate Examination Committee member

• September 17th, 2013 - PhD Candidate: Dr. I.J. Nixon (United Kingdom)
• October 17th 2014 - PhD Candidate: Dr. J. Pramana (Netherlands)
• November 17th 2015 - PhD candidate: Dr. H. van Monsjou (Netherlands)
• December 11th 2018 - PhD Candidate: Dr. Tihana Ibrahimpasic (United States)
• January 18th, 2021 - PhD Candidate: Dr. Laura Wang (Australia)
• June 2nd, 2021 - PhD Candidate: Dr. Caroline Verhagen (Netherlands)

Conference Faculty

• Advanced Laryngopharyngeal Cancer: Functional Preservation and Rehabilitation, Portsmouth, June 25th - 26th, 2020 (postponed due to COVID) - Chairman
• Functional Preservation and Rehabilitation after Treatment for Advanced Laryngeal Cancer, Portsmouth, March 14th - 15th, 2019 - Chairman
• Portsmouth Parathyroid Conference, Portsmouth, December 14th 2018 – Chairman

Editorial Roles

• European Journal of Surgical Oncology

Associate Editor

January 1st 2023 – present

• European Journal of Surgical Oncology

Guest Editor

March issue 2018, Volume 44, Issue 3, p275-378 - Special issue on thyroid cancer management

• Journal of Oral Pathology and Medicine

Guest Editor

November issue 2021, Volume 51, Issue 10 - Special issue on vascular malformations and tumors of the head and neck

• Scientific Journal Reviewer

Oral Oncology, European Journal of Surgical Oncology, Journal of Surgical Oncology, Head and Neck, International Journal of Cancer

• Scientific Project and Grant Reviewer

Netherlands: Dutch Cancer Society

France: Institute National du Cancer

Awards

• New York Head and Neck Society

Annual Meeting, New York, NY, March 2002

Title of study presented: “MUC1 is a target if 1q amplification and pertains a grave clinical prognosis in papillary thyroid cancer”

Invited Lectures

• European Society of Surgical Oncology meeting, Krakow, 2016
• Barcelona Society of Neurosurgery, Annual Meeting, Baqueira, Spain, February, 2017
• University of Edinburgh, Department of Otolaryngology Academic Conference, March 17th 2017
• Medilex: Performance of Medical Specialists, Zeist, Netherlands, November 9th 2017
• Medilex: Performance of Medical Specialists, Driebergen, Netherlands, October 11th 2017
• Wessex Head and Neck and Thyroid Network Education Day, May 3rd, 2017
• Portsmouth Parathyroid Conference, Portsmouth, UK, December 14th 2018
• Global Post-laryngectomy Rehabilitation Academy, Portsmouth, UK, March 14th 2019
• Health Care Quality Conference, Beverwijk, Netherlands, March 25th, 2019

Published Research Reports

• The growing precision of diagnostic pathways in thyroid nodule evaluation. 

Bekker J, Wreesmann VB. 

Eur J Surg Oncol. 2025 Jan;51(1):109374.

• Special issue: Management of vascular tumors and malformations of the head and neck. 

Oomen KPQ, Brennan PA, Wreesmann VB. 

J Oral Pathol Med. 2022 Nov;51(10):829.

• Angiosarcomas of the head and neck: Impact of large data analysis on clinical management. 
•  
• Wreesmann VB, Oomen KP, Brennan PA. 

J Oral Pathol Med. 2022 Nov;51(10):904-910.

• Current classification of vascular anomalies of the head and neck. 

Oomen KPQ, Wreesmann VB. 

J Oral Pathol Med. 2022 Nov;51(10):830-836.

• A novel classification of carotid body tumors.

Wreesmann VB, Nixon IJ. 

Eur. J. Surg. Oncol. May, 2021

• Management of the contralateral central neck in differentiated thyroid cancer: A contentious issue. 

Shaha AR, Tuttle RM, Wreesmann VB. 

Eur. J. Surg. Oncol. 2021 Apr;47(4):717-719.

• Improvement of oral cancer screening quality and reach: The promise of artificial intelligence. 
•  
• Kar A, Wreesmann VB, Shwetha V, Thakur S, Rao VUS, Arakeri G, Brennan PA. 

J Oral Pathol Med. 2020 Mar 11

• The risk-benefit ratio of chemoradiation treatment in head and neck squamous cell carcinoma: value of extranodal spread and margin status. 

Ammar M, Wreesmann VB. 

Journal of ENT Masterclass, Yearbook 2018, Volume 11, Nr. 1, December 1st, 2018

• Nasal obstruction secondary to an inverted midline supernumerary tooth. 

Jones L, Hilton JM, Heyman J, Viswanathan H, Wreesmann VB, Hayes SM. 

Ann R Coll Surg Engl. 2019 Jan;101(1)

• Fanconi anemia and homologous recombination gene variants are associated with functional DNA repair defects in vitro and poor outcome in patients with advanced head and neck squamous cell carcinoma. 

Verhagen CVM, Vossen DM, Borgmann K, Hageman F, Grénman R, Verwijs-Janssen M, Mout L, Kluin RJC, Nieuwland M, Severson TM, Velds A, Kerkhoven R, O'Connor MJ, van der Heijden M, van Velthuysen ML, Verheij M, Wreesmann VB, Wessels LFA, van den Brekel MWM, Vens C. 

Oncotarget. 2018 Apr 6;9(26):18198-18213.

• Complete nasal obstruction secondary to pacemaker insertion. 

Jones TL, Wreesmann VB, Nilssen E, Hilton J, Hayes SM. 

Ann R Coll Surg Engl. 2018 May;100(5)

• Optimization of the risk-benefit ratio of differentiated thyroid cancer treatment. 

Nasef HO, Nixon IJ, Wreesmann VB. Eur J Surg Oncol. 

2018 Mar;44(3):276-285. Review.

• The risk/benefit ratio of differentiated thyroid cancer treatment: Exploring treatment de-escalation. 

Wreesmann VB; on behalf of EJSO. 

Eur J Surg Oncol. 2018 Mar;44(3):275.

• Aggressive differentiated thyroid cancer. 

Janjua N, Wreesmann VB. 

Eur J Surg Oncol. 2018 Mar;44(3):367-377. Review.

• Role of extracapsular nodal spread and surgical margin status in defining high-risk head and neck squamous cell carcinoma and its treatment intensity. 

Wreesmann VB. 

International Journal of Head and Neck Surgery, April-June 2017; 8(2): 76-83.

• An International Multi-Institutional Validation of Age 55 Years as a Cutoff for Risk Stratification in the AJCC/UICC Staging System for Well-Differentiated Thyroid Cancer.              

Nixon IJ, Wang LY, Migliacci JC, Eskander A, Campbell MJ, Aniss A, Morris L, Vaisman F, Corbo R, Momesso D, Vaisman M, Carvalho A, Learoyd D, Leslie WD, Nason RW, Kuk D, Wreesmann V, Morris L, Palmer FL, Ganly I, Patel SG, Singh B, Tuttle RM, Shaha AR, Gönen M, Pathak KA, Shen WT, Sywak M, Kowalski L, Freeman J, Perrier N, Shah JP. 

Thyroid. 2016 Mar;26(3):373-80.

• Influence of extracapsular nodal spread extent on prognosis of oral squamous cell carcinoma. 
•  
• Wreesmann VB, Katabi N, Palmer FL, Montero PH, Migliacci JC, Gönen M, Carlson D, Ganly I, Shah JP, Ghossein R, Patel SG. 

Head Neck. 2016 Apr;38 Suppl 1:E1192-9.

• Defining a Valid Age Cutoff in Staging of Well-Differentiated Thyroid Cancer. 

Nixon IJ, Kuk D, Wreesmann V, Morris L, Palmer FL, Ganly I, Patel SG, Singh B, Tuttle RM, Shaha AR, Gönen M, Shah JP. 

Ann Surg Oncol. 2015 Jul 28.

• Prognostic value of vascular invasion in well-differentiated papillary thyroid carcinoma.
•  
• Wreesmann VB, Nixon IJ, Rivera M, Katabi N, Palmer F, Ganly I, Shaha AR, Tuttle RM, Shah JP, Patel SG, Ghossein RA. 

Thyroid. 2015 May;25(5):503-8.

• Head and neck squamous cell carcinoma in young patients.

van Monsjou HS, Wreesmann VB, van den Brekel MW, Balm AJ. 

Oral Oncol. 2013 Dec;49(12):1097-102.

• Oral and oropharyngeal squamous cell carcinomas in young patients: The Netherlands Cancer Institute experience. 

van Monsjou HS, M Lopez-Yurda, M. Hauptmann, Balm AJ, van den Brekel MM, Wreesmann VB. 

Head Neck. 2013 Jan;35(1):94-102.

• Oropharyngeal squamous cell carcinoma: a unique disease on the rise?

van Monsjou HS, Balm AJ, van den Brekel MM, Wreesmann VB. 

Oral Oncol. 2010 Nov;46(11):780-5.

• Closure of tracheoesophageal fistula with prefabricated revascularized bilaminar radial forearm free flap. 

Wreesmann VB, Smeele LE, Hilgers FJ, Lohuis PJ. 

Head Neck. 2009 Jun;31(6):838-42.

• Clinical impact of molecular analysis on thyroid cancer management. 

Wreesmann VB, Singh B. 

Surg Oncol Clin N Am. 2008 Jan;17(1):1-35.

Genetic abnormalities associated with chemoradiation resistance of head and neck squamous cell carcinoma. 

van den Broek GB, Wreesmann VB, van den Brekel MW, Rasch CR, Balm AJ, Rao PH. 

Clin Cancer Res. 2007 Aug 1;13(15 Pt 1):4386-91.

• Association of CD44 V3-containing isoforms with tumor cell growth, migration, matrix metalloproteinase expression, and lymph node metastasis in head and neck cancer. 

Wang SJ, Wreesmann VB, Bourguignon LY. 

Head Neck. 2007 Jun;29(6):550-8.

• Downregulation of Fanconi anemia genes in sporadic head and neck squamous cell carcinoma. 
•  
• Wreesmann VB, Estilo C, Eisele DW, Singh B, Wang SJ. 

ORL J Otorhinolaryngol Relat Spec. 2007;69(4):218-25. Epub 2007 Apr 4.

• Patterns of expression of cell cycle/apoptosis genes along the spectrum of thyroid carcinoma progression. 
•  
• Saltman B, Singh B, Hedvat CV, Wreesmann VB, Ghossein R. 
•  
• Surgery. 2006 Dec;140(6):899-905; discussion 905-6.

• Repetitive endoscopic sinus surgery failure: a role for radical surgery? 

Videler WJ, Wreesmann VB, van der Meulen FW, Knegt PP, Fokkens WJ. 

Otolaryngol Head Neck Surg. 2006 Apr;134(4):586-91.

• MUC1 plays a role in tumor maintenance in aggressive thyroid carcinomas. 
•  
• Patel KN, Maghami E, Wreesmann VB, Shaha AR, Shah JP, Ghossein R, Singh B. 
•  
• Surgery. 2005 Dec;138(6):994-1001; discussion 1001-2.

• Chromosomal aberrations in squamous cell carcinomas of the upper aerodigestive tract: biologic insights and clinical opportunities. 

Wreesmann VB, Singh B. 

J Oral Pathol Med. 2005 Sep;34(8):449-59. Review.

• Molecular profiling of tumor progression in head and neck cancer.
•  
• Belbin TJ, Singh B, Smith RV, Socci ND, Wreesmann VB, Sanchez-Carbayo M, Masterson J, Patel S, Cordon-Cardo C, Prystowsky MB, Childs G. 
•  
• Arch Otolaryngol Head Neck Surg. 2005 Jan;131(1):10-8.

• Identification of novel prognosticators of outcome in squamous cell carcinoma of the head and neck. 

Wreesmann VB, Shi W, Thaler HT, Poluri A, Kraus DH, Pfister D, Shaha AR, Shah JP, Rao PH, Singh B. 

J Clin Oncol. 2004 Oct 1;22(19):3965-72.

• Follicular variant of papillary thyroid carcinoma: genome-wide appraisal of a controversial entity. 

Wreesmann VB, Ghossein RA, Hezel M, Banerjee D, Shaha AR, Tuttle RM, Shah JP, Rao PH, Singh B. 

Genes Chromosomes Cancer. 2004 Aug;40(4):355-64.

• Genome-wide profiling of papillary thyroid cancer identifies MUC1 as an independent prognostic marker. 

Wreesmann VB, Sieczka EM, Socci ND, Hezel M, Belbin TJ, Childs G, Patel SG, Patel KN, Tallini G, Prystowsky M, Shaha AR, Kraus D, Shah JP, Rao PH, Ghossein R, Singh B. 

Cancer Res. 2004 Jun 1;64(11):3780-9.

• Genetic abnormalities associated with nodal metastasis in head and neck cancer. 

Wreesmann VB, Wang D, Goberdhan A, Prasad M, Ngai I, Schnaser EA, Sacks PG, Singh B. 

Head Neck. 2004 Jan;26(1):10-5.

• Human papillomavirus DNA and p53 polymorphisms in squamous cell carcinomas from Fanconi anemia patients. 
•  
• Kutler DI, Wreesmann VB, Goberdhan A, Ben-Porat L, Satagopan J, Ngai I, Huvos AG, Giampietro P, Levran O, Pujara K, Diotti R, Carlson D, Huryn LA, Auerbach AD, Singh B. 
•  
• J Natl Cancer Inst. 2003 Nov 19;95(22):1718-21.

• Chromosomal aberrations in patients with head and neck squamous cell carcinoma do not vary based on severity of tobacco/alcohol exposure. 

Singh B, Wreesmann VB, Pfister D, Poluri A, Shaha AR, Kraus D, Shah JP, Rao PH. 

BMC Genet. 2002 Nov 14;3:22. Epub 2002 Nov 14.

• Genome-wide appraisal of thyroid cancer progression. 
•  
• Wreesmann VB, Ghossein RA, Patel SG, Harris CP, Schnaser EA, Shaha AR, Tuttle RM, Shah JP, Rao PH, Singh B. 
•  
• Am J Pathol. 2002 Nov;161(5):1549-56.

• Refractory chronic sinusitis: evaluation of symptom improvement after Denker’s procedure. 
•  
• Wreesmann VB, Fokkens WJ, Knegt PP. 
•  
• Otolaryngol Head Neck Surg. 2001 Nov;125(5):495-500.

• Inflammatory pseudotumour (inflammatory myofibroblastic tumour) of the pancreas: a report of six cases associated with obliterative phlebitis. 
•  
• Wreesmann V, van Eijck CH, Naus DC, van Velthuysen ML, Jeekel J, Mooi WJ. 
•  
• Histopathology. 2001 Feb;38(2):105-10.

• Screening for genetic aberrations in papillary thyroid cancer by using comparative genomic hybridization. 
•  
• Singh B, Lim D, Cigudosa JC, Ghossein R, Shaha AR, Poluri A, Wreesmann VB, Tuttle M, Shah JP, Rao PH. 
•  
• Surgery. 2000 Dec;128(6):888-93;discussion 893-4.

Abstracts (Presentations at scientific meetings):

• Genome-wide screening for genetic prognostic factors in papillary thyroid carcinoma. 
•  
• Wreesmann VB, Ghossein RA, Poluri A, Shaha AR, Tuttle RM, Shah JP Rao PH, Singh B. 

Fifth International Conference on Head and Neck Cancer San Francisco, CA, July 2000.

• Hierarchical Clustering (HC): a Novel Approach to Evaluating the Prognostic Value of Laboratory Parameters in Patients (Pts) Undergoing Chemoradiation Treatment (CRT) for Advanced Laryngopharyngeal Carcinoma (LPC). 

Singh B, Pfister D, Wreesmann VB, Li R, Gogineni S, Bosl G, Hoffman RH, Shah JP, Rao PH. 

37th Annual Meeting of the American Society of Clinical Oncology; New Orleans LA, May 2001.

• Gain of 1q is unique to the tall cell variant of papillary thyroid cancer. 

Wreesmann VB, Ghossein RA, Tuttle RM, Shaha AR, Robbins R, Shah JP, Rao PH, Singh B. 

73rd annual meeting of the American Thyroid Association, Washington D.C. November 2001.

• MUC1 is a target of 1q amplification and pertains a grave clinical prognosis in papillary thyroid cancer. 

Wreesmann VB, Sieczka E, Socci ND, Hezel M, Belbin TJ, Childs G, Patel SG, Shah JP, Rao PH, Ghossein RG, Singh B. 

Annual Meeting of the New York Head and Neck Society, New York, NY, March 2002.

• Genome wide screening identified gains and losses as independent prognostic variables in patients with head and neck squamous cell carcinoma (HNSCC). 

Singh B, Wreesmann VB, Thaler HT, Shi W, Shah JP, Shaha AR, Kraus DH, Boyle JO, Pfister D, Rao PH. 

38th Annual Meeting of the American Society of Clinical Oncology; Orlando, Fl May 2002.

• p53 inactivation by human papillomavirus (HPV) in Fanconi anemia associated squamous cell carcinoma. 

Kutler DI, Goberdhan A, Wreesmann VB, Giampietro PF, Auerbach AD, Singh B. 

The Sixth Research Workshop on the Biology, Prevention, and Treatment of Head and Neck Cancer; Washington D.C.; October 2002.

• Identification of novel prognostic factors in head and neck squamous cell carcinoma. 
•  
• Wreesmann VB, Shi W, Thaler HT, Shah JP, Shaha AR, Kraus DH, Boyle JO, Pfister D, Rao PH, Singh B. 

7th symposion on Research in Head and Neck Cancer; Dusseldorf, Germany, September 4-6 2003.

• Molecular profiling of aggressive papillary thyroid cancer: prognostic significance of MUC1 alterations. 

Wreesmann VB, Sieczka E, Socci ND, Hezel M, Belbin TJ, Childs G, Patel SG, Patel KN, Tallini G, Prystowsky M, Shaha AR, Kraus D, Shah JP, Rao PH, Ghossein RA, Singh B. 

7th symposion on Research in Head and Neck Cancer; Dusseldorf, Germany, September 4-6 2003.

• Chromosomal aberrations in Fanconi anemia-associated squamous cell carcinomas differ from sporadic squamous cell carcinomas from the general population. 

Kutler DI, Rao PH, Wreesmann VB, Goberdhan A, Ngai I, Huvos AG, Giampietro PF, Levran O, Pujara K, Diotti R, Auerbach AD, Singh B. 

15th annual Fanconi Anemia Research Fund scientific symposium, Houston TX, Oct 2003.

• Molecular classification of Fanconi anemia(FA)-associated head and neck squamous cell carcinoma (HNSCC) using oligonucleotide microarrays. 

Kutler DI, Ganly I, Wreesmann VB, Goberdhan A, Ngai I, Huvos AG, Giampietro PF, Levran O, Pujara K, Diotti R, Auerbach AD, Singh B. 

15th annual Fanconi Anemia Research Fund scientific symposium, Houston TX, Oct 2003.

•  
• Genotyping follicular cell-derived thyroid neoplasia: a CGH study of 150 cases.

Wreesmann VB, Ghossein RA, Socci N, Shaha AR, Tuttle RM, Shah JP, Rao PH, Singh B. 

Sixth International Conference on Head and Neck Cancer, Washington DC, August 2004.

• Downregulation of Fanconi anemia genes in sporadic squamous cell carcinomas of the head and neck. 

Wreesmann VB, Estilo C, Eisele DW, Singh B, Wang SJ. 

208th meeting of the Netherlands Society of Otolaryngology-Head and Neck Surgery, Utrecht, April 7th 2006.

• Extracapsular nodal spread does not predict outcome in clinically node negative oral cavity squamous cell carcinoma. 

Wreesmann VB, Ghossein RA, Carlson D, Ganly I, Palmer F, Montero P, Shah JP, Patel SG. 

AHNS 2013 Annual Meeting, April 10 & 11, 2013, Orlando Florida.

• Minor (<2mm) extracapsular spread is not an adverse predictor of outcome in metastatic squamous cell carcinoma of the oral cavity. 

Wreesmann VB, Ghossein RA, Carlson D, Ganly I, Palmer F, Montero P, Shah JP, Patel SG. Presented at the AHNS 2014 Annual Meeting, July 2014, New York, New York.

Books, Chapters:

• Molecular Biology as applied to Head and Neck Oncology

Wreesmann VB, Singh B.

Stell and Maran's Textbook of Head and Neck Surgery and Oncology

Fifth Edition

Chapter, edited by John Watkinson and Ralph Gilbert

• Molecular-Cytogenetic Characterization of Head and Neck Cancer: Identification of molecular prognostic factors and targets of therapy

Wreesmann VB, Singh B.

Book, Amsterdam 2004

Reviewed in: Head and Neck: Volume 29, Issue 1, pages 82–83, January 2007

• Open Conservation Surgery for Laryngeal Cancer

Wreesmann VB, Ganly I

Scott-Brown's Otorhinolaryngology and Head and Neck Surgery, Eighth Edition

Chapter 27

CRC Press, Taylor-Francis Group, June 12th, 2018

• Molecular Oncology

Wreesmann V.B.

Self-Assessment in Head and Neck Surgery and Oncology, First Edition

Chapter 21

Elsevier 2014

Research grants:

Netherlands Cancer Institute “Startgeld” Grant 2008

Project: Fanconi anemia in head and neck cancer

Principal investigators: Wreesmann VB, van den Brekel MW, Balm AJM, Vens C.

Amount granted: 300.000 euro