Best Spinal cord stimulator (SCS) neurosurgeons: TOP 30 doctors

Scientific degree, name, surname: Specialist. Dr. Teyub Hasanov

Medical Division: Neurosurgery

Education:

Dokuz Eylul University, Turkey - September 2002 - June 2009

Marmara University Faculty of Medicine – Department of Brain and Neurosurgery, Turkey June 2010 – June 2015

Work experience:

Fatih University Hospital Brain and Neurosurgery (Teacher) - 2015-2016

Bahcheshehir University Medical Park Goztepe and VM Medical Park Pendik Hospital Brain and Neurosurgery (Associate Professor's Assistant) - 2016-2021

Bona Dea Hospital - 2021-2023

Special Educational Programs in Neurosurgery:

Cranial Base Surgery Cadaver Course: September 20-21, 2013, Marmara University Institute of Neurological Sciences; ISTANBUL

Course Director: Associate Professor Ashkin Sheker

The VI Evidence-Based Multidisciplinary Neuro-Oncology Symposium - November 01-02, 2013, Point Barbaros Hotel, Istanbul, Turkey

Chairman of Neuro-Oncology Society: Prof. Dr. M. Ibrahim ZIYAL

Turkish Neurosurgery Society Endoscopic Skull Base Surgery Cadaver Course: November 15-16, 2013, Marmara University Institute of Neurological Sciences; ISTANBUL

World Federation of Neurosurgical Societies Cranial Base Surgery Cadaver Course: June 2011, Istanbul 

Turkish Neurosurgery Society the 26th Scientific Congress: April 20-24, 2012, Belek, Antalya 

Turkish Neurosurgery Society the 27th Scientific Congress: April 12-16, 2013, Belek, Antalya

Courses in Fundamentals of Neurosurgery:

Period 4, Course 1, March 10-20, 2016, Cheshme, Izmir

Period 4, Course 2, February 15-19, 2017, Cheshme, Izmir

Period 4, Course 3, March 14-18, 2018, Cheshme, Izmir

Period 4, Course 4, March 20-23, 2019, Belek, Antalya

Scientific Works:

A. Presentations and Articles at International Scientific Meetings

Ozoner B., Gungor A., ​​Hasanov T., Toktas Z.O., & Kilij T. (2020).

Neurosurgical practice during the coronavirus disease 2019 (COVID-19) pandemic. World Neurosurgery, 140, 198-207.

Mikayilli M., Hasanov T., Otluoglu G.D., Najitarhan D.E., Toktas Z.O., & Cholak A. (2020). Congenital lateral encephalocele - case report. Child Nervous System, 36 (12), 3119-3122.

Mikayilli M., Hasanov T., Otluoglu G.D, Najitarhan D.E., Erdogan, R.B.A, Demir N, ... & Cholak A. (2019). Spontaneous idiopathic cerebrospinal fluid rhinorrhea. Journal of Craniofacial Surgery.

Otluoglu G. D., Hasanov T., Mert B., Toktas Z.O., Konya D., & Demir M.K. (2019). Missed microcatheter breakage and cauda equina migration after endovascular neurointervention for dural arteriovenous fistula as a rare cause of tethered spinal cord: a case report. Journal of Neurosurgery: Spine, 32(4), 607-610.

Yilmaz B., SHENER S., TEYYUB H., AKAKIN A., YAPIJIER O., & Demir M.K. (2018). Visual qualitative assessment of apparent diffusion coefficient quantification and Ki-67 proliferation index of diffusion-weighted imaging to predict atypia in surgical meningiomas. Marmara Medical Journal, 31(2), 68-75.

DEMIR Mustafa Kemal, YAPIJIER Ozlem, HASANOV Teyyub, KILICH Deniz, KILICH Türker. Rapidly expanding calvarial Langerhans cell histiocytosis with low Ki-67 in adults: a difficult diagnosis on magnetic resonance imaging. Journal of Neuroradiology, 2018, 31.4: 390-394.

DEMIR Mustafa Kemal, YAPICIER Ozlem, HASANOV Teyyub, YILMAZ Baran, KILICH Turker. Hydatid disease: MR image of calvarium and superior sagittal sinus spread. Journal of Neuroradiology, 2018, 31.3: 320-323.

DEMIR Mustafa Kemal, YAPIJIER Ozlem, HASANOV Teyyub, GUNDUZ Mehmet Alp, KILICH Turker. Systemic large B-cell non-Hodgkin's lymphoma presenting as a massive hemorrhagic intracerebral mass. Diagnostic and invasive imaging, 2017, 98.10: 737.

UNAL E, ANTAR V, HASANOV T, GUZEL A, KILICH K. P16. 32 Primary brain lymphomas. Case report and literature review. Neurooncology, 2017, 19. Supplement 3: iii. 115.

Demirchi G, Hasanov T, Bayri Y, Konya D "Occipitocervical Fusion in Craniovertebral Junction Pathologies" Congress of Neurological Surgeons 2013 Annual Meeting, San Francisco, CA, 2013

B. Articles Published in International Peer-Reviewed Journals:

Hasanov T, Cholak A. Orbital tumors in childhood. Bagdatoglu C, editor. Overview of Pediatric Central Nervous System Tumors From Diagnosis to Treatment. 1st Edition. Ankara: Turkey Clinics; 2021. pp. 85-7.

Teyyub Hasanov; AKAKIN Akin; Kilij Turker. Management of Treatment in Arteriovenous Malformations. Turkish Clinics Neurosurgery – Special Topics, 2019, 9.1: 20-26.

Murat Shakir Ekshi, Teyyub HASANOV, Yashar BAYRI, Mustafa İbrahim ZIYAL, Ashkin Sheker, "Jasper Stone-Like Skull: Massive Cranial Metastasis with Leptomeningeal Flow - A Rare Case Report", Journal of Neurological Sciences (in Turkish), 2013, Volume 30, Issue 4, p. 776-779.

Ozgur Chelik, Teyyub HASANOV, Suheyla Uyar BOZKURT, Yashar BAYRI, Mustafa Ibrahim ZİYAL, "Granulocytic Sarcoma of the Cavernous Sinus Presenting with Trigeminal Neuralgia", Turkish Journal of Neurosurgery 2013, Volume: 23, Number: 3, p. 327-330.

Murat Shakir Ekshi, Teyyub Hasanov, Baran Yilmaz, Akin Akakin, Yashar Bayri, Suheyla Uyar Bozkurt, Turker Kilij, "Isolated breast cancer metastasis to the pituitary gland" Indian Journal of Neurology 2014, Volume 62, pp70-71.

Murat Shakir Ekshi, Teyyub Hasanov, Suheyla Uyar Bozkurt, Yashar Bayri, M. Ibrahim Ziyal, "Two Different Primary Tumors in the Same Brain - Case Report and Literature Review", Journal of Neurological Sciences, 2014, Volume 31, Issue 3, p. 635-640. 6 p.

Bahattin TANRIKULU, Teyyub HASANOV, Suheyla UYAR BOZKURT, Ashkin Sheker, "Schwannoma Similar to Sacral Pure Spinal Epidural Cavernoma: A Case Report", Journal of Neurological Sciences, 2015, Volume 32, Issue 2, pp. 412-417

Articles presented at international scientific meetings and published in collections of scientific works:

Ekshi M.S, Demirji G, Hasanov T, Chelik O, Bayri Y "Familial Chiari Malformation", Turkish Neurosurgery Society 26th Annual Scientific Congress, April 20-24, 2012, Belek, Antalya

Atik A.F, Hasanov T, Chelik O, Bayri Y, Konya D, "Posttraumatic Epidural Hematoma and Retroorbital Abscesses: Case Report", Turkish Neurosurgery Society 26th Annual Scientific Congress, April 20-24, 2012, Belek, Antalya

Doğrul R, Ekshi M.S, Hasanov T, Bayri Y, Konya D, "Migration of Instrumental Material into the Abdomen in a Surgically Treated Spondylolisthesis Patient", Turkish Neurosurgery Society 27th Annual Scientific Congress, April 12-16, 2013, Belek, Antalya

Hasanov T, Ekshi M.S, Chelik O, Bayri Y, Bozkurt S.U, Ziyal I, "Isolated Cavernous Sinus Myeloid Sarcoma Presenting with Trigeminal Neuralgia", Turkish Neurosurgery Society 27th Annual Scientific Congress, April 12-16, 2013, Belek, Antalya

Yilmaz B. Toktas Z. Konya D. Hasanov T. Intracranial Complications of Lumbar Spinal Surgery.

D. Book Section

Akin A, Hasanov T. Fundamentals of Surgical Treatment in Parkinson's Disease. Bijeroglu H, Tonge M, Sechkin M, Adiguzel E, Gurvit H, Hanji M, editors. Movement Disorders Surgery: 2019.

Hasanov T, Toktas Z. Spinal Injuries. Furunjuoglu Y. Emergency Medical Manual. Gunesh Medical Bookstores: 2020 
 

Neurosurgery Training: Gazi University, Department of Neurosurgery, 2011 

H index: 10, I10 Index: 12 Citations: 296

 Dr Mehmet Tonge has international and nationwide 32 publications, 12 book chapters, 92 oral and poster presentations and 41 invited lectures, mostly on Stereotactic and Functional Neurosurgery. 

Work & Training experience:

2004-2011: Gazi University, Department of Neurosurgery (Residency)

 2008: Zurich University Hospital, Department of Neurosurgery (Intraoperative MRI applications), Switzerland 

2008: Zurich University Hospital, Department of Neurosurgery: Microneurosurgery, white matter dissection, interventional neuroradiology courses, Switzerland 

2011 – 2012: Sinop Ataturk State Hospital, Neurosurgeon

 2012 – 2013: Cankiri State Hospital, Neurosurgeon 

2013 – 2014: Istanbul Medipol University, Department of Neurosurgery & Gamma Knife Center (Ass Prof) 

2013 – now: Maastricht University Neurosurgery & Neuroscience Department (Visiting scientist, PhDc) The Netherlands 

2014: Maastricht University, The Netherlands: Deep Brain Stimulation Fellowship 2014-2018: Istanbul Memorial Hospital Neurosurgery: Staff Neurosurgeon

 2016-2018: Istanbul Florence Nightingale Hospital (Consultant, Gamma Knife Center) 

2018-now: Istanbul Medipol University (Stereotactic & Functional Neurosurgery, Gamma Knife Center) Ass. Prof.) 

Dr Mehmet Tonge has completed 4-year cycle EANS (European Association of Neurosurgical Societies) Training courses. 

Clinical areas of interest:

 • Stereotactic & Functional Neurosurgery

 • Surgery for movement disorders

• * MR Guided Focused Ultrasound (MRgFUS)

 • Gamma Knife Radiosurgery 

• Surgery for pain & spasticity 

• Psychosurgery

Research areas of interest: 

• Deep brain stimulation

• * MR Guided Focused Ultrasound (MRgFUS)

 • Stereotactic radiosurgery 

Administrative duties:

 • Turkish Neurosurgical Society, Sterotactic & Functional Neurosurgery Section: Board member 2015- 2017 

• Turkish Neurosurgical Society, Sterotactic & Functional Neurosurgery Section: Board member (Secretary) 2017-2019

 • Turkish Skull Base Society: Board member 2016-2018

 • Turkish Skull Base Society: Supervisory board member 2018-2020

 • Deep Brain Stimulation and Movement Disorders Surgery Society: Executive Board Member, (Accountant) 2023-still 

Memberships: 

• WSSFN (World Stereotactic & Functional Neurosurgery Society) 

• ESSFN (European Stereotactic & Functional Neurosurgery Society)

 • Deep Brain Stimulation and Movement Disorders Surgery Society

 • Deep Brain Stimulation Society 

• International Stereotactic Radiosurgery Society 

• Leksell Gamma Knife Society 

• EANS (European Association of Neurosurgical Societies) 

• Turkish Neurosurgical Society

• Turkish Skull Base Society

Sample Publications: 

1. Tonge M. Technological developments in electric based DBS. Deep Brain Stimulation 2024 4(36-41) DOI: https://doi.org/10.1016/j.jdbs.2023.12.001 

2. Akgul E, Onan HB, Islek I, Tonge M, Durmus Y, Barburoglu M, Azizova A, Erol C, Hakyemez B, Sencer S, Aydin K, Arat A. Flow diverter stents in the treatment of recanalized intracranial aneurysms. Interv Neuroradiol. 2021 Aug;27(4):481-489. doi: 10.1177/1591019921990507. Epub 2021 Jan 28. PMID: 33509011; PMCID: PMC8580529. 

3. Mulders AEP, Temel Y, Tonge M, Schaper FLWVJ, van Kranen-Mastenbroek V,Ackermans L, Kubben P, Janssen MLF, Duits A. The association between surgical characteristics and cognitive decline following deep brain stimulation of the subthalamic nucleus in Parkinson's disease. Clin Neurol Neurosurg. 2021 Jan;200:106341. doi: 10.1016/j.clineuro.2020.106341. Epub 2020 Nov 3. PMID: 33160716. 

4. Wetzelaer P, Vlis T, Tonge M, Ackermans L, Kubben P, Evers S, Kocabicak E, Temel Y. Management of Hardware Related Infections after DBS Surgery: A Cost Analysis. Turk Neurosurg. 2018;28(6):929- 933. doi: 10.5137/1019-5149.JTN.21511-17.1. PMID: 29465741. 

5. Bedirli N, Emmez G, Ünal Y, Tönge M, Emmez H. Effects of positive end- expiratory pressure on intracranial pressure during pneumoperitoneum and Trendelenburg position in a porcine mode. Turk J Med Sci. 2017 Nov 13;47(5):1610-1615. doi: 10.3906/sag-1609-17. PMID: 29152942. 

6. Sari R, Tonge M, Bolukbasi FH, Onoz M, Baskan O, Silav G, Elmaci I. Management of Failed Cranioplasty. Turk Neurosurg. 2017;27(2):201-207. doi: 10.5137/1019-5149.JTN.15395-15.0. PMID: 27593759. 

7. Tonge M, Kocabicak E, Ackermans L, Kuijf M, Temel Y. Final Electrode Position in Subthalamic Nucleus Deep Brain Stimulation Surgery: A Comparison of Indirect and Direct Targeting Methods. Turk Neurosurg. 2016;26(6):900-903. doi: 10.5137/1019-5149.JTN.13739-14.1. PMID: 27337232. 

8. Tonge M, Ackermans L, Kocabicak E, van Kranen-Mastenbroek V, Kuijf M, Oosterloo M, Kubben P, Temel Y. A detailed analysis of intracerebral hemorrhages in DBS surgeries. Clin Neurol Neurosurg. 2015 Dec;139:183-7. doi: 10.1016/j.clineuro.2015.10.017. Epub 2015 Oct 23. PMID: 26513430. 

9. Silav G, Bölükbaşı FH, Özek E, Tönge M, Önöz M, Elmacı İ. A Simple Technique for Bone Storage after Decompressive Craniectomy in Children. Pediatr Neurosurg. 2015;50(3):161-4. doi: 10.1159/000381748. Epub 2015 May 14. PMID: 25998533. 

10. Yilmaz MB, Donmez H, Tonge M, Senol S, Tekiner A. Vertebrojugular arteriovenous fistula and pseudoaneurysm formation due to penetrating vertebral artery injury: case report and review of the literature. Turk Neurosurg. 2015;25(1):141-5. doi: 10.5137/1019-5149.JTN.8247-13.1. PMID: 25640560. 

11. Kurt G, Tönge M, Çeltıkçı E, Çapraz I, Serdaroğlu A, Bılır E. Surgery for intractable temporal lobe epilepsy: experience of a single institution. Turk J Med Sci. 2014;44(5):866-70. doi: 10.3906/sag-1307- 30. PMID: 25539559. 

12. Yılmaz MB, Tönge M, Emmez H, Kaymaz F, Kaymaz M. Neuroprotective effects of quetiapine on neuronal apoptosis following experimental transient focal cerebral ischemia in rats. J Korean Neurosurg Soc. 2013 Jul;54(1):1-7. doi: 10.3340/jkns.2013.54.1.1. Epub 2013 Jul 31. PMID: 24044072; PMCID: PMC3772279. 

13. Yilmaz MB, Egemen E, Tonge M, Kaymaz M. Transoral protrusion of a peritoneal catheter due to gastric perforation 10 years after a ventriculoperitoneal shunting: case report and review of the literature. Turk Neurosurg. 2013;23(2):285-8. doi: 10.5137/1019-5149.JTN.4904-11.1. PMID: 23546921. 

14. Omerhodzic I, Tonge M, Matos B, Musabeliu E, Raspanti C, Ferdinandov D, Galimova R, Muroi C, Balik V, Kursumovic A. Neurosurgical training programme in selected European countries: from the young neurosurgeons' point of view. Turk Neurosurg. 2012;22(3):286-93. doi: 10.5137/1019- 5149.JTN.5133-11.0. PMID: 22664994. 

15. Ergun E, Kurt G, Tonge M, Aytar H, Tas M, Baykaner K, Ceviker N. Effects of phenytoin sodium on dura mater healing in a rat model of CSF leakage. Turk Neurosurg. 2011;21(4):471-6. PMID: 22194102. 

16. Emmez H, Tonge M, Tokgoz N, Durdag E, Gonul I, Cevıker N. Radiological and histopathological comparison of microporous polysaccharide hemospheres and oxidized regenerated cellulose in the rabbit brain: a study of efficacy and safety. Turk Neurosurg. 2010 Oct;20(4):485-91. doi: 10.5137/1019- 5149.JTN.3300-10.2. PMID: 20963698. 

17. Emmez H, Yildirim Z, Kale A, Tönge M, Durdağ E, Börcek AO, Uçankuş LN, Doğulu F, Kiliç N, Baykaner MK. Anti-apoptotic and neuroprotective effects of α-lipoic acid on spinal cord ischemiareperfusion injury in rabbits. Acta Neurochir (Wien). 2010 Sep;152(9):1591-600; discussion 1600-1. doi: 10.1007/s00701-010-0703-9. Epub 2010 Jun 10. PMID: 20535507. 

18. Kurt G, Tonge M, Börcek AO, Karahacioglu E, Gurel O, Baykaner K, Ceviker N, Aykol S. Fractionated gamma knife radiosurgery for optic nerve tumors: a technical report. Turk Neurosurg. 2010 Apr;20(2):241-6. doi: 10.5137/1019-5149.JTN.1681-09.3. PMID: 20401852. 

19. Emmez H, Kale A, Tönge M, Cakir A, Ceviker N. Two meningiomas with different histological grades in the same patient. Case report. Neurol Med Chir (Tokyo). 2010;50(8):686-8. doi: 10.2176/nmc.50.686. PMID: 20805656.

Work Experience:

• 2011-2014 (Haziran) Kütahya Tavşanlı Doç. Dr. Mustafa Kalemli Hospital

• 2014(Haziran)-2019 ( Haziran) Kütahya Özel Anadolu Hospital

• 2019- 2020 İstanbul Arnavutköy Hosptial

• 2020- 2023 Özel İstanbul Şafak Hospital

• 2024 -halen OrtoCare Clinic

Education:

▪ 1989-1993 Erzurum High School

▪ 1993-1994 İzmir 60. Yıl High School

▪ 1994-1997 İzmir 60. Yıl High School

▪ 1997-2004 Dokuz Eylül University Medicine Faculty

▪ 2005-2011 Dokuz Eylül Universtiy Orthopaedics and Traumatology Department

Profesional Experience:

• Joint and Cartilage Surgery and Stem Cell treatment

• Sports Medicine and Joint Arthroscopy

• Joint Arhtroplasty (knee- hip-shoulder prothesis)

• Hand Surgery and Microsurgery

• Spinal Surgery

• Traumatolgy

Postgraduate Education:

• 2006 Orthopaedic Trauma Course

• 2008 Monolateral Eksternal Fixator Course

• 2009 Prof. Dr. Rıdvan Ege Han Surgery Course

• 2009 Advanced Orthoapedic Trauma Course

• 2009 Based Arthroscopy Course

• 2010 AO Trauma Course ( Principles in Operative Fracture Treatment)

• 2010 3.Based İntrameduller Nailing Course

• 2011 AO Trauma Course (Advances in Operative Fracture Treatment)

• 2011 2. Advanced İntrameduller Nailing Course

• 2011 XII. Advanced Artrhroscopy Course

• 2012 Ankle Arthroscopy Course

• 2012 Shoulder Artrhroscopy Course

• 2013 AO Trauma Masters Course

• 2013 Knee Arthroplasty and Revision Arthroplasty Course ( Viyana/ Avusturya)

• 2015 Primer and Revision Knee Artrhroplasty Course( Arthroschool Courses)

• 2016 Master Knee Arthroscopy Course ( Acıbadem Univ./ İstanbul )

• 2020 Live lig spinall instrumentation kursu (Medtronic İstanbul)

Congress and Symposiums

• 2002 Eğitim Programı Geliştirme Sempozyumu

• 2004 III. National Medicine Education Congress

• 2017 National Medicine Student Congress

• 2008 8th İnternational Turkish Spine Congress

• 2009 XXI. National Orthopaedy and Traumatology Congress

• 2010 12. National Hand and Upper Extremity Surgery Congress

• 2001 II. National Medicine Education Congress

• 2011 XXII. National Orthopaedy and Traumatology Congress

• 2012 10. ArthroplastyWinter Congress

• 2012 13th European Federation of National Associations of Orthopaedics and Traumatology Congress

• 2012 13. National Hand and Upper Extremity Surgery Congress

• 2013 Osteosynthese İnternational 2013

• 2013 14th European Federation of National Associations of Orthopaedics and Traumatology Congress

• 2014 10th Central European Orthopaedic Congress

• 2014 24. National Orthopaedy and Traumatology Congress

• 2015 25, National Orthopaedy and Traumatology Congress

• 2016 26. National Orthopaedy and Traumatology Congress

• 2017 Eurospine 2017 Congress Ireland

Bibliography:

• 2011 XXII. Ulusal Türk Ortopedi ve Travmatoloji Kongresi Poster Bildirisi (İNTRAMEDULLER

ÇİVİLEME YÖNTEMİ İLE OPERE EDİLEN TİBİA CİSİM KIRIKLI HASTALARIN TAKİBİNDE

KULLANILAN RADYOGRAFİK KAYNAMA SKORLAMA SİSTEMİNİN GÜVENİLİRLİĞİNİN

HASTA KLİNİĞİ İLE DOĞRULANMASI )

• 2013 Osteosynthese İnternational 2013 and İntramedullary Nailing Courses Oral Presentation

(F1.4 Verification of the reliability of the radiographic union score for tibial fractures in

the follow-up of patients with tibia corpus fractures operated via the intramedullary

nailing technique using the patients’ clinical condition. E. Cekic1, E. Alici2,)

• 2014 10th Central European Orthopaedic Congress Oral Presentation ( The Reliability of

Radiographic Union Score).

• Reliability of the Radiographic Union Score for Tibial Fractures Acta Orthop Traumatol Turc

2014;48(5):533-540 doi: 10.3944/AOTT.2014.14.002

• Prediction of tibial nonunion at the 6-week time point Keir A. Ross, Kevin O’Halloran, Renan C.

Castillo, Max Coale, Justin Fowler, Jason W. Nascone, Marcus F. Sciadini, Christopher T. LeBrun,

Theodore T. Manson, Anthony R. Carlini, Josef E. Jolissaint, Robert V. O’Toole*

• Reprodutibilidade do escore radiográfico de consolidac¸ão das fraturas da tíbia (RUST) Fernando

Antonio Silva de Azevedo Filhoa,b,∗, Ricardo Britto Cotiasa, Matheus Lemos Azib e Armando Augusto

de Almeida Teixeiraa

• Does weight-bearing assignment after intramedullary nail placement alter healing of tibial shaft

fractures? D.A. Greenhilla,∗, M. Poormanb, C. Pinkowskib, F.V. Ramseyb, C. Haydela

• Will My Tibial Fracture Heal? Predicting Nonunion at the Time of Definitive Fixation Based on

Commonly Available Variables

Kevin O’Halloran MD, Max Coale BA, Timothy Costales BS,Timothy Zerhusen Jr BS, Renan C. Castillo PhD,

Jason W. Nascone MD,Robert V. O’Toole MD

• Feasibility and Value of Radiographic Union Score Hip Fracture after Treatment with Intramedullary

Nail of Stable Hip Fractures

• Image quality of cone beam computed tomography for evaluation of extremity fractures in the presence

of metalhardware: visual grading characteristics analysis

1GREG M OSGOOD, MD, 2GAURAV K THAWAIT, MD, 2NIMA HAFEZI-NEJAD, MD,

2DELARAM SHAKOOR, MD,1ADAM SHANER, MD, 3JOHN YORKSTON, PhD, 4WOJCIECH B

ZBIJEWSKI, PhD, 4JEFFREY H SIEWERDSEN, PhDand 2SHADPOUR DEMEHRI, MD

• Correlation Between RUST Assessments of Fracture Healing to Structural

and Biomechanical Properties

Margaret E. Cooke,1 Amira I. Hussein,1 Kyle E. Lybrand,1 Alexander Wulff,1 Erin Simmons,1

Jeffrey H. Choi,1 Jody Litrenta,1William M. Ricci,2 Jason W. Nascone,3 Robert V. O’Toole,3 Elise F.

Morgan,4 Louis C. Gerstenfeld,1 Paul Tornetta III1

• EXPLORING PROGNOSTIC FACTORS ASSOCIATED WITH

ADVERSE OUTCOMES IN PATIENTS WITH FRACTURES OF THE

TIBIAL SHAFT

By RAMAN MUNDI, MD, BHSc

A Thesis Submitted to the School of Graduate Studies in Partial Fulfillment of the

Requirements for the Degree Master of Science

McMaster University

• Value of a radiographic score for the assessment of healing of nailed femoral

and tibial shaft fractures: A retrospective preliminary study

Vasiliki Perlepea,⁎, Andrea Ceratoa, Dan Putineanua, Celine Buglib, Guy Heynend,

Patrick Omoumia,c, Bruno Vande Berga

About me

I graduated from Izmir Dokuz Eylul University with the orthopedics branch. After I graduated, I carried out some

studies focusing on especially on

joint and cartilage surgery and stem cells. In this, I worked with many professional and amateur sport clubs. Also,

I worked on joint replacement surgery

for further aged people. Approximately, I achieved 10 thousand people who took knee and hip replacement

surgery from me. I attended to many international conferences about joint and cartilage surgery. Now I start

Ortocare Clinic for orthopedics and health center. In here, I treat my patients using the most advanced

technologies in the world, such as foot health centers, electromagnetic therapy, cryocabin therapy, backup

therapy and stem cell therapy. In our clinic, I continue to my work on non-surgical treatments, especially antiaging

treatment, and to eliminate pain problems in patients. On top of that, I also carry out some post-operative

rehabilitation and medical plates exercises.

Education

• (1998-2004), Bachelor's Degree Hacettepe University Faculty of Medicine, Ankara
• (2005-2010), Doctorate / Specialization in Medicine Haydarpaşa Numune Training and Research Hospital

Experience

• 2005-2011, Assistant Doctor Haydarpaşa Numune Training and Research Hospital, Department of Radiology
• 2011-2013, Specialist Doctor Kahramanmaraş Women's and Children's Hospital, Kahramanmaraş Necip Fazıl City Hospital (mandatory service)
• 2013-2022, Specialist Doctor Ministry of Health Fatih Sultan Mehmet Training and Research Hospital, Department of Radiology
• 2022, Associate Professor Ministry of Health Fatih Sultan Mehmet Training and Research Hospital, Department of Radiology

Prof. Erkan Kaptanoğlu, M.D. was born in Balikesir, Turkey in 1966. After completing his primary school, secondary school and high school education in Balikesir, he graduated from Istanbul University, Cerrahpasa Faculty of Medicine in 1990. He completed his internship at Peterborough District Hospital and Lincoln County Hospital in the United Kingdom. After a year of compulsory medical service, he completed his residency, which he had started in 1992, at Ankara Numune Training and Research Hospital in 1997 and became a Neurosurgery Specialist. After being assigned at the same hospital as Chief Resident in the same year, he studied “spinal cord injury and spinal cord regeneration” as a “research fellow” alongside Prof. Charles Tator, M.D., at the University of Toronto Faculty of Medicine in 1998-1999. After returning from Canada in 1999, he was tasked by the Ministry of Health to establish a Field Hospital and to work in cooperation with the Turkish Red Crescent Society at Hakkari, Şemdinli for two months. Following this assignment, he volunteered to work for the 1999 Marmara Earthquake relief effort.

He became an Associate Professor of Neurosurgery in 2004. He earned the title Doctor of Science (Ph.D.) by completing a doctorate program on Advanced Neuroscience between 2000-2005, at Hacettepe University Institute of Medical Sciences. He joined the project for autologous stem cell therapy in human spinal cord injuries with the Departments of Neurosurgery and Hematology at the Ankara University Faculty of Medicine. In 2009, he was appointed as Deputy Chief to the 1st Neurosurgery Clinic at the Ankara Numune Hospital, where he had been working.

At this hospital, in which he worked until 2010, he supervised and attended complex cranial, pediatric, spinal, trauma and vascular neurosurgery operations. He continued his academic research at Ankara University, Department of Anatomy and research laboratories of Ankara University and Hacettepe University for the purpose of developing strategies for complex spinal surgery operations.

With his research on spinal cord injuries and spinal anatomy, he won many awards such as the Acibadem Hospital Medical Research Award, 1st Place in 2000, Turkish Neurosurgical Society Dr. Mahir Tevruz Scientific Research Award, Tübitak and Brain Research Society Wheyt Award in 2001, Turkish Neurosurgical Society Hamit Ziya Gokalp Young Neurosurgeons Research Award, 2nd Place in 2002, Turkish Neurosurgical Society Yildiz Yalcinlar Scientific Research Award in 2004.

In 2010, he went to Cyprus to found the Near East University Faculty of Medicine Hospital with the guidance of Hacettepe University, and was appointed as full Professor. Between 2010-2015, he served as the Founder and Head of Department at the Near East University and Founder and Deputy Chief Physician at the University Training and Research Hospital in TRNC.

In 2000-2001, he served as a member of the editorial board for Türk Nöroşirurji Dergisi and Turkish Neurosurgery journal. Between the years 2001-2006, he served as an assistant editor for Türk Nöroşirurji Dergisi and Turkish Neurosurgery journals. In 2002-2003, he served as the Chairman of the Young Neurosurgeons Committee under the Turkish Neurosurgical Society. He was elected to the Turkish Neurosurgical Society Spinal and Peripheral Nerve Surgery Group Board of Directors to serve between 2003-2009. In 2013, he was again elected as a member to the Turkish Neurosurgical Society Spinal and Peripheral Nerve Surgery Group Board of Directors. In 2015, he became the Chairman of the Turkish Neurosurgical Society Spinal and Peripheral Nerve Surgery Group Board of Directors. In 2018, he was elected as a member to the Board of Turkish Neurosurgery Academy.

In 2015, he was appointed to the Marmara University Faculty of Medicine, Department of Neurosurgery and was elected as the Head of Department. During the same period, he also served as the Director of the Institute of Neuroscience. In 2018, he completed his tenure as the Head of Department. Reaching the end of this tenure in 2019, he retired from his duties as the Director of the Institute of Neuroscience and as a Member of the Faculty of Medicine. During his tenure at Marmara University, he supervised and accompanied surgical operations for complex cases from cranial patients to brain tumors (gliomas, meningiomas and hypophysis adenomas in particular), cerebral hemorrhages, Parkinson’s disease, trauma and vascular neurosurgery. He performed complex spinal surgery operations such as surgeries for spinal deformities (e.g. scoliosis and kyphosis), thoracoscopic spinal surgeries and sacral tumor surgeries. He conducted research and experimental studies on stem cell therapy and regeneration in spinal cord injuries. Between 2019-2020, currently He continues his clinical practice and surgeries along with his local and international academic studies, from his private clinic and Istanbul Brain and Spine Center.

He has attended numerous national and international courses and meetings as an instructor and speaker, was a guest speaker in over 100 events and conferences. He has published 65 international, 35 national scientific articles, edited 7 books, written 52 book chapters. He has served in the organizational committee 5 times in international meetings and 22 times in national meetings.

He is a member of the Turkish Medical Association, Turkish Cypriot Medical Association, Turkish Neurosurgical Society, Turkish Spine Society, EUROSPINE, AO Spine, Turkish Neurosurgery Academy.

Assoc. Prof. Ozdogan, M.D., Ph.D., completed his education at Yeditepe University Health Sciences Institute in the Molecular Medicine Doctorate Program under Prof. Dr. Turgay İsbir, and he also studied at Saint Louis University in Arkansas, USA, with Prof. Dr. M. Gazi Yasargil. He pursued a Clinical Fellowship in Brain and Nerve Surgery at Yeditepe University Hospital, guided by Prof. Dr. Yasargil and Prof. Dr. Uğur Türe. Additionally, he underwent specialization training at Ufuk University Faculty of Medicine, the Faculty of Medicine at Gazi University, and completed his secondary education at İçel Anatolian High School.

Professionally, he has held various positions, including Faculty Member in the Department of Neurosurgery at Haliç University, and Associate Professor at Private Adatip Istanbul Hospital and Biruni University Hospital. He has also served as an Associate Professor at S.B.U. Kartal, Sancaktepe, and Istanbul Training and Research Hospitals, and worked as a Chief Assistant at S.B.U. Gaziosmanpaşa Taksim and Kartal Training and Research Hospitals. His earlier roles include Specialist Doctor at S.B.U. Baltalimanı Bone Diseases Hospital and Mus State Hospital, as well as Clinical Fellow at Yeditepe University Faculty of Medicine Hospital.

Assoc. Prof. Özdoğan is a member of several professional associations, including the Turkish Neurosurgery Association, Turkish Spine Association, and the Turkish Neurosurgery Society’s Neuroanatomy, Neurovascular, and Neurooncology Groups. He is also affiliated with the European Association of Neurosurgical Societies.

HOMO HOMINI MEDICUS. Eclectic surgeon, specialist in orthopedics and traumatology, pioneer of endoscopic surgery, radio-guided and minimally invasive robotics of the spine and small and large joints (knee, hip, foot, shoulder, elbow and wrist). He combines surgery with regenerative medicine, which he was the first to launch in Italy and Europe, with the use of FSV cells (Stromal Vascular Fraction, particularly rich in stem cells). Adolfo Panfili boasts a prestigious scientific and sporting curriculum of international importance, as well as being an expert in homeopathy, homotoxicology, phytotherapy, acupuncture and BEST chiropractic. Expressly commissioned by his teacher, Prof. Linus Pauling (multiple Nobel Prize winner), inventor of Orthomolecular medicine, he founded AIMO, (International Association of Orthomolecular Medicine), revisiting this science and merging it with other super-specialist branches, including regenerative medicine , aimed at restoring and repairing cartilage, bone and joint structures, vertebral discs, ligaments, tendons, etc.

Prof Adolfo Panfili, orthopedic surgeon with a very long CV of international standing. He is president of AIMO, the International Association of Orthomolecular Medicine of which he is the founder. He was a student of the double Nobel Prize winner Linus Pauling, inventor of Orthomolecular medicine. Prof Panfili has revisited and expanded this science by merging it with other sciences and techniques including the use of Stromal Vascular Fraction.

– He is Deputy Rector for International Relations as well as Dean of the Master's Faculty of Orthomolecular Sciences at the Popolare University of Milan;

– He is the first to have carried out minimally invasive robotic surgery in orthopedics in Italy with the Mazor system;

– He is Trainer and Proctor of Dtrax, a minimally invasive posterior cervical fusion and distraction system;

– He is the Director of various High Technology Minimally Invasive Spinal Surgery Centers accredited with the NHS and otherwise;

– He is the founder and director of the first Italian Center for Minimally Invasive Robotic Spine Surgery and one of the most eminent members of robotic surgery at the “International Academy for Robotic Spine Surgery”;

Prof. Panfili has been treating vertebrae, posture and nutrition in close synergy since the beginning of his thirty-year professional activity, both from a surgical and manipulative point of view, being among other things the first orthopedist in Europe to graduate in Best Chiropractic with Prof. Ted Morter, one of the best chiropractors in the world, of whom he was the best European student.

– He is currently a pioneer in the use and application of the Stromal Vascular Fraction in the field of well-being, anti-aging and longevity, with particular reference to orthopaedics, the spine and cervical, the aspect of cartilage damage for prevention of degenerative diseases of the hips, knees and intervertebral discs.

Education and Specialization:

• Medical Degree: Hacettepe University Faculty of Medicine (1981)
• Specialization in Neurosurgery: Kocaeli University Faculty of Medicine, Neurosurgery Department

Professional Experience:

• 1994-1998: Associate Professor and Head of the Neurosurgery Department, Kocaeli University
• 1998-Present: Professor and Head of the Neurosurgery Department, Kocaeli University
• Current Position: Neurosurgeon at VM Medical Park Pendik Hospital

International Experience:

• 1993: Observer at The Midland Centre for Neurosurgery and Neurology, Birmingham, UK
• Trained in syringomyelia and stereotactic neurosurgery under Bernard Williams, M.D., and Edward R. Hitchcock, M.D.

Clinical Experience:

• Performed over 5629 endoscopic surgeries including:
  • 4384 Pituitary Adenomas
  • 209 Rathke's Cleft Cysts
  • 152 Craniopharyngiomas
  • 121 Chordomas/Chondrosarcomas
  • 98 Tuberculum Sellae Meningiomas and other pathologies in the sellar region

Research and Publications: Prof. Dr. Savaş Ceylan has numerous publications in internationally recognized journals, covering a wide range of neurosurgical topics. His research includes pioneering work in endoscopic transsphenoidal surgery for pituitary tumors and other sellar region pathologies.

Professional Memberships:

• American Association of Neurological Surgeons (AANS)
• Congress of Neurological Surgeons (CNS)
• Academia Eurasiana Neurochirurgica
• International Federation of Neurosurgical Societies (IFNE)
• World Federation of Neurosurgical Societies (WFNS) Skull Base Committee
• Turkish Neurosurgery Association
• Turkish Society of Nervous System Surgery

Awards:

• 2016 Turkish Neurosurgery Association Service Award
• Scientific Publication Awards from Kocaeli University

Education:

Medical Faculty, Trakya University,  

Edirne, Turkey (1994-2000)

Professional Experience:

General Practitioner and Emergency Physician

Bartın (2000-2004)

Specialization:  

Department of Neurosurgery, S.B. Göztepe Training and Research Hospital,  

Istanbul (2004-2010)

Participation in the Accreditation Process by the European Association of Neurosurgical Societies (EANS) during  

Specialization (2004-2010)

Completion of Compulsory Service as Specialist Physician

Tokat State Hospital, Tokat (2010-2012)

Assistant Professor, Department of Neurosurgery

Gaziosmanpaşa University, Tokat (2012-2014)

Contribution to the Establishment of the Department of Neurosurgery at Medipol University  

(2012-2014)

Lecturer

Medipol University, Istanbul (2012-2014)

Specialist Physician

Memorial Istanbul Hospitals, Istanbul (2014-2018)

Lecturer, Faculty of Health Sciences

Eurasia University, Istanbul (2014-2021)

Associate Professor in the field of Neurosurgery (2021- )

Specialist Physician

Acıbadem Maslak Hospital, Istanbul (2018-2021)

Specialist Physician

Liv Hospital Ulus, Istanbul (2021-2023)

2023 –

Istanbul Florence Nightingale Hospital, Istanbul

Skills and Achievements:

Obtained Associate Professorship in the field of Neurosurgery (2021)

Experience in Academic Teaching and Management (2012-2021)

Proficiency in Turkish (Native) and English (Advanced)

Specializations

Brain Tumors

Aneurysm Surgery

Pituitary Surgery

Spine Surgery

Waist neck and back hernias

Spine Tumors

Spinal Fractures

Peripheral Nerve Surgery

Faculty of Medicine Hacettepe School of Medicine (1994-2001)

Specialty training: Istanbul Training and Research Hospital (2002-2008)

In 2015, he was awarded the title of Associate Professor.

On February 01, 2021, he was promoted to Professor.

Professional Positions:

• Consultant MD, Balıkesir Military Hospital (2008-2009)

• Consultant MD, Şanlıurfa Training and Research Hospital (2009-2011)

• Assistant Professor MD, Dicle University, Department of Orthopedics and Traumatology (2011-2017)

• Associate Professor MD, Istanbul Medipol University, Faculty of Medicine, Department of Orthopedics and Traumatology (2017-2020)

• Professor MD, Istanbul Medipol University, Faculty of Medicine, Department of Orthopedics and Traumatology (2021 – Ongoing)

• 2017;Yakın Doğu Üniversite Hastanesi
• 2015 - 2017; Aksaz Asker Hastanesi
• 2010 - 2015; GATA Haydarpaşa Eğitim Hastanesi Ankara
• 2001 - 2007; GATA Tıp Fakültesi Ankara

Specializations

Arthroscopic Surgery (Knee, Shoulder, Ankle)

Arthroplasty Surgery (Knee, Hip, Joint Prostheses)

Pediatric Orthopedics

Hand and Upper Extremity Surgery

Micro Surgery - Hand Surgery

Lengthening and Deformity Surgery

Athlete Injuries

Trauma (Fracture) Surgery

Experience

Beylikbağı Health Center (2008-2009)

Gebze Fatih State Hospital (2009-2013)

Kocaeli University Faculty of Medicine (2013-2018)

Gulf State Hospital (2018-2022)

Gebze Fatih State Hospital (2022-2023)

HospitalPark Darıca Hospital (2023-....)

Education

19 Mayıs University Faculty of Medicine 2001-2008

Kocaeli University Faculty of Medicine Specialization 2013 -2018

EDUCATION:

• Turhan and Mediha Tansel Primary School (1979–1984)
• Kültür College (1984–1988)
• Semiha Şakir High School (1988–1991)
• Marmara University Faculty of Medicine (1991–1997)
• Marmara University Faculty of Medicine, Neurosurgery Department, Specialist Training (1997–2002)
• Title of Associate Professor in Neurosurgery (May 31, 2021)

ADDITIONAL TRAINING:

• "Visiting Physician," University of Southern California, Department of Neurosurgery (1998)
• "Microsurgery Training," GATA (Gülhane Military Medical Academy), Ankara Education and Research Hospital (2003)

PROFESSIONAL EXPERIENCE:

• Gülhane Military Medical Academy Haydarpaşa Training and Research Hospital (2002–2003)
• Dr. Lütfi Kırdar Kartal Training and Research Hospital (2003–2005)
• Private Avicenna Ataşehir Hospital (2005–2012)
• Private 29 Mayıs Hospital (2012–2013)
• Maltepe State Hospital (2013–2018)
• Kartal Dr. Lütfi Kırdar City Hospital (2018–2020)
• Private Academic Hospital (2020–2022)
• Hisar Intercontinental Hospital (2022–2024)
• Private Medipol Acıbadem Regional Hospital (2024–Present)

ADMINISTRATIVE AND ACADEMIC ROLES:

• Board Member, Neurosurgical Society (2006–2009)
• Head of the Emergency Department, Maltepe State Hospital (2014–2016)
• Deputy Chief Physician, Private Academic Hospital (2020–2021)
• Advisory Board Member, Beykent University Faculty of Medicine (2018–2024)
• Faculty Member, Galata University Faculty of Health Sciences (2022–2024)
• Director, Continuous Education Center, Galata University (2022–2024)

Dr. Nooshin is Specialist Neurologist with more than 10 years of extensive experience in her field. She earned his medical degree and board certification of neurology from the most prestigious university in Iran, Tehran University of Medical Sciences. Further, she pursued advanced training through a fellowship in headache disorders at the Danish Headache Centre, University of Copenhagen, under the supervision of Professor Jes Olesen, who is well-known as the godfather of the headache around the world. She also attended a two years mastership program of headache disorders at the University of Copenhagen. She is a fellow of European Headache Federation and a member of the Educational Committee of the International Headache Society.

EXPERTISE:

• Treating and diagnosing different types of headaches
• Botox injection and nerve blocks for treating headache disorders
• Diagnosing and treatment of spine disorders (low back pain, cervical pain, discopathy)
• Treatment of vertigo, tinnitus, sleep disorders and dementia
• Diagnosis and treatment of muscle and nerve disorders (Carpal Tunnel Syndrome, polyneuropathy, myopathy, myasthenia gravis)
• Treatment of stroke, epilepsy, multiple sclerosis
• EEG, EMG-NCV, VEP

Piya Assawaboonyadej, M.D.

Medical School: Suleyman Demirel University, 2004

Neurosurgery Training: Gazi University, Department of Neurosurgery, 2011

Dr Mehmet Tonge has international and nationwide 32 publications, 12 book chapters, 92 oral and poster presentations and 41 invited lectures, mostly on Stereotactic and Functional Neurosurgery.

Work & Training experience:

2004-2011: Gazi University, Department of Neurosurgery (Residency)

2008: Zurich University Hospital, Department of Neurosurgery (Intraoperative MRI applications), Switzerland

2008: Zurich University Hospital, Department of Neurosurgery: Microneurosurgery, white matter dissection, interventional neuroradiology courses, Switzerland

2011 – 2012: Sinop Ataturk State Hospital, Neurosurgeon

2012 – 2013: Cankiri State Hospital, Neurosurgeon

2013 – 2014: Istanbul Medipol University, Department of Neurosurgery & Gamma Knife Center (Ass Prof)

2013 – now: Maastricht University Neurosurgery & Neuroscience Department (Visiting scientist, PhDc) The Netherlands

2014: Maastricht University, The Netherlands: Deep Brain Stimulation Fellowship 2014-2018: Istanbul Memorial Hospital Neurosurgery: Staff Neurosurgeon

2016-2018: Istanbul Florence Nightingale Hospital (Consultant, Gamma Knife Center)

2018-now: Istanbul Medipol University (Stereotactic & Functional Neurosurgery, Gamma Knife Center) Ass. Prof.)

Dr Mehmet Tonge has completed 4-year cycle EANS (European Association of Neurosurgical Societies) Training courses.

Clinical areas of interest:

• Stereotactic & Functional Neurosurgery

• Surgery for movement disorders

• Gamma Knife Radiosurgery

* Surgery for pain & spasticity

* Psychosurgery

Research areas of interest:

* Deep brain stimulation

• Stereotactic radiosurgery