Reception and waiting area at Ospedale Santa Maria, modern clinic interior in Italy

Patient room at Ospedale Santa Maria with modern beds and comfortable amenities

Mammography room at Ospedale Santa Maria Bari with doctor consulting patient

Waiting area at Ospedale Santa Maria with modern seating and indoor plants

Doctor consultation with couple at Ospedale Santa Maria clinic, Italy

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Italy, Bari

Infertility Treatment in Ospedale Santa Maria

7 patients

chose clinic for Reproductology Treatment

About the clinic

Infertility treatment at Ospedale Santa Maria in Bari, Italy, offers a full path from diagnosis to advanced reproductive techniques. An initial consultation is free, with full IVF treatment cycles costing around $4,075 to $4,650, and donor embryo packages around $7,877. The clinic's reproductive medicine unit has over 30 years of experience and is affiliated with a major international network.

Diagnostic Approach

The clinic provides thorough fertility diagnostics. This workup helps identify the cause of infertility. Available tests include:

Andrology laboratory analysis
Spermiogram
Detailed hormonal analysis
Ultrasound monitoring and other imaging

Treatment Methods

The center performs over 1,200 procedures yearly. Dr. Pasquale Totaro leads the team with 31 years of expertise and 1,000+ procedures performed. He is a member of ESHRE and SIGO. The clinic offers a complete range of assisted reproduction techniques.

Non-surgical and Surgical Options

Intrauterine Insemination (IUI): A first-line, non-surgical treatment.
In Vitro Fertilization (IVF): The clinic has performed over 10,000 egg retrievals.
Intracytoplasmic Sperm Injection (ICSI): For severe male factor infertility, offered since 1991.
Embryo culture to blastocyst: Improves embryo selection before transfer.

Additional Fertility Services

Cryopreservation (Vitrification): For freezing sperm, eggs, or embryos.
Heterologous fertilization: Anonymous sperm or egg donor programs.

Treatment Packages and Pricing

The clinic provides clear package options. Each package includes medical visits, lab tests, and the core procedures. Flights and accommodation are not included.

1-cycle IVF Package: Typically costs between $4,075 and $4,650. It covers monitoring, egg retrieval, embryo transfer, and follow-up tests.
3-cycle IVF Package: May cost around $12,960 for three attempts.
Embryo Donation Package: Costs around $7,877 and includes donor embryos and the transfer procedure.

With its long-standing expertise and comprehensive care model, Ospedale Santa Maria provides a structured approach to fertility treatment. You can discuss your specific situation directly with their specialists.

Highlights

1969 Year of foundation

400 doctors

Most Popular Clinic for Infertility Treatment

9000 patients per year

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Average answering time – 5 minutes

Treatments prices in the clinic

Last price update — 29.03.2025. Prices can be changed depending on the medical case and doctor's recommendations.

Reproductology

treatment	Price
Embryo Donation	$7877
In Vitro Fertilization (IVF)	$4075 - $4650
Embryo cryopreservation	Price on request
Cryopreservation of sperm	Price on request
Artificial Insemination	Price on request
Testicular sperm extraction (TESE)	Price on request
Testicular sperm aspiration (TESA)	Price on request

Clinic Doctors

Reproductive endocrinologist

Pasquale Totaro

Reproductive endocrinologist, Obstetrician-gynecologist, Gynecologist

Experience 33 years

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Licences

Institutional accreditation certificate for Ospedale Santa Maria, Bari, Puglia Region

hospital accreditations of quality

Patient choice for IVF

UA, Patient choice for IVF certificate for Ospedale Santa Maria

Patient choice for Check-up

UA, Patient choice for Check-up certificate for Ospedale Santa Maria

Ospedale Santa Maria: more details about the clinic

Italy, Bari

Medically Assisted Reproduction (MAR) and Infertility Center

Ospedale Santa Maria in Bari, a multi-specialist hospital structure accredited with the National Health Service, is part of GVM Care & Research and is a point of reference for Italy for diagnosis, therapy, and research in the field of male infertility and femininity, with 30 years of experience. Its Medically Assisted Procreation Center provides a complete path of support for couples who have difficulty conceiving: from gynecological and andrological examinations to diagnostic imaging, up to first level (intrauterine insemination) and second level (in vitro fertilization) help techniques IVF and intracytoplasmic sperm injection ICSI), cryopreservation of semen, oocytes, and embryos, heterologous fertilization with a donation of both female and male gametes, without forgetting psychological counseling, which is essential to accompany the couple throughout the process.

Ospedale Santa Maria in Bari was one of the first centers in Italy to use the ICSI technique, performing over 10,000 egg retrievals since 1991, resulting in approximately 2,500 pregnancies and as many children. With an average of 1,200 first- and second-stage procedures per year, the center performs more than one-third of the procedures in the region. Santa Maria Hospital is a national reference point for medically assisting reproduction (MAP) and is the health facility with the highest volume of procedures in southern Italy. The medically assisted procreation programs of the Ospedale Santa Maria have the most innovative international protocols.

The Infertility Treatment Center is also active in the research field. It implements protocols to help patients understand the importance of correct prevention and accurate information, then a timely diagnosis of infertility, targeted treatments, and, where necessary, the conservation of one's gametes as an investment for tomorrow.

According to a public reporting portal of Italian healthcare facilities, comparing the performance of the facilities based on the data released by the Istituto Superiore di Sanità (MAP Register), Ospedale Santa Maria - GVM Care & Research of Bari is in first position for number of cycles of IUI, intrauterine insemination — level I technique, while for the number of oocyte thawing procedures - level II and III technique — the hospital of Santa Maria occupies the 4th place in the national ranking.

Additional services

Language assistance

Available

free

Accommodation

Hotel (apartments) near the clinic, billed daily

Patient reviews

Google 4

5 Google reviews

Peter Edholm

Aug 29, 2022

Spotless experience with friendly and professional service. I recently went for PCR where they also assisted in filling out the necessary forms to be able to travel. My father in law also had surgery here, and he had the same great experience. My go to place in Puglia, highly recommended.

Giuliana Marrese

Oct 10, 2025

Impressive facility, welcoming, very kind. The staff were excellent at making me feel at ease. I felt at home. The nursing staff was diligent, attentive, and very professional! And very well-trained! Very efficient services and very short wait times. The best cardiology department in Puglia. The head physician, Dr. Izzo, is very professional, and the head nurse, Dr. Ernesto, is a very humane person. Humanity is the key word. A truly special thank you to the cardiology nurses who make the hospital stay so peaceful and family-like! I sincerely thank everyone! Thank you, Santa Maria Cardiology.

Antonio Torchiaro

Oct 6, 2025

I would like to express my sincere gratitude to the entire clinic team for their professionalism, expertise, and compassionate approach throughout my treatment. The surgery was a success thanks to the extraordinary skill of Professors Ludovico and Pagliarulo, whose attentiveness and helpfulness instilled confidence and reassurance from the very beginning. A special thanks to the head nurse, always present and attentive to every patient's need, and to the nursing and healthcare staff, especially Angela and Rosa, for their kindness, patience, and smiles, which make the post-operative period more peaceful. In this facility, you feel not just a patient, but a person who is truly listened to and cared for. An example of healthcare excellence in every respect. Congratulations and heartfelt thanks to everyone.

Nicolò Bucci

Oct 14, 2025

I began my journey to address and combat my illness in a top-notch facility in Milan. After several trips, expenses, and, above all, extremely long waits, I left without any resolution. Therefore, I decided to turn to the Santa Maria Clinic, which quickly allowed me to be admitted and have surgery. I'm writing these lines because I found an excellent environment and staff, first and foremost Dr. Ludovico and his colleagues on the urology team, the anesthetists and operating room nurses, but especially the urology ward nurses and healthcare assistants who, from the moment I walked in until I was discharged, welcomed me and provided me with excellent care. When you're battling a terrible disease, finding people like this is the best medicine. In conclusion, we often make journeys of hope to facilities up north, but we also have excellent healthcare here, and we must make the most of it. Therefore, to the entire urology ward team, I simply say THANK YOU, THANK YOU, THANK YOU.

Studio Legale Ciliento

Sep 5, 2025

I thank Professor Giuseppe Speziale and the Cardiac Surgery Department at Santa Maria Hospital for performing, in June 2025, with excellence and high professionalism, a delicate heart operation to replace an organic mitral valve prosthesis implanted in 2011 with a mechanical one. The surgery was performed using video-assisted minithoracotomy, meaning without opening the sternum, despite the fact that, in my case, it was a repeat operation and despite the fact that I had previously undergone breast cancer surgery with a silicone prosthesis. Just seven days after the surgery, I returned home (after spending two days in intensive care and five days on the ward) without any pain or discomfort. Within a month, with some respiratory and cardiocirculatory rehabilitation (performed at the same hospital, thanks to excellent physiotherapists), I returned to an active life. I was unfamiliar with this particular surgical approach, because many Italian facilities continue to operate in the traditional manner, that is, by opening the sternum, causing immense physical and psychological suffering for the patient, who is forced to recover much more slowly and painfully (I had personally experienced this years before). I was terrified at the mere thought of undergoing a second sternotomy, until I met Prof. Giuseppe Speziale, who immediately reassured me, dispelling all my doubts and uncertainties, instilling in me a great sense of security that comes from a profound awareness of his own professional skills and abilities. This is an innovative surgical technique, practiced at the Santa Maria Hospital in Bari (and I'm proud of this, since it's my hometown), and one that many Italian healthcare facilities aren't even familiar with. Today, a couple of months later, I feel compelled to write these lines to sincerely thank Prof. Giuseppe Speziale, who for years has brilliantly managed the entire cardiac surgery department with high levels of expertise and professionalism, surrounded by a first-class team endowed with great availability and humanity. My most sincere thanks go to all the medical and paramedical staff of the Cardiac Surgery Department and the Intensive Care Unit at Santa Maria Hospital in Bari, who have cared for me continuously, even post-operatively, with skill, professionalism, and immense humanity. A special applause, from the bottom of my heart, goes to all of Prof. Speziale's staff. Giuseppe Speziale, to the cardiac surgeons, the interventionalists, the anesthetists, the very young nurses in the intensive care unit like Alessandro Miacola, to Chiara, the head nurse of the intensive care unit, who with delicate kindness fixed my cap to hold back my long hair as soon as I woke up, to all the nurses in the cardiac surgery department like Michele, Elisenda, Rosy, Florianna, Simona and all the others, to the head nurse of the cardiac surgery unit, Ms. Doriana, who welcomed me from the first moment as if I were at home, to Ms. Dina who always supported me throughout my hospital journey to complete the bureaucratic procedures. I owe a special thanks to all those who have accompanied me on this journey, giving me their smiles and words of comfort every day. I refer in particular to all the staff and healthcare workers like Lidia, Marilena, Maria, Angela, Anka, and Marta; to the cleaning ladies like Nicla and Anna, who dedicate themselves with sacrifice and dedication to their work every day, never sparing themselves, but always capable of offering us a smile or a kind gesture; and to the physiotherapists like Marica and Giuseppe, who supported me throughout my rehabilitation journey on the ward with great expertise, humanity, and availability. My deepest thanks go to the entire Cardiac Surgery Department, and my deepest respect to the GVM Group. Thank you, thank you, thank you! Francesca Paola Ciliento