Prof Dr Serdar Kabatas

Dr. Serdar Kabatas, graduated from Trakya University Medical Faculty, Edirne/Turkey in 1997. He became a neurosurgeon-specialist- in 2003 and then gained an award for postdoctoral fellowship in Spinal Cord Injury (SCI) and Neural Stem Cell (NSC) at Harvard Medical School in 2007. He has spent most of his scientific carrier in the study of SCI related stem cell applications either experimentally or clinically, stem cell clinical applications in hypoxic-ischemic encephalopathy, traumatic brain injury, cerebral palsy, autism spectrum disorders, periferic nervous system injuries, cell-based approaches for intervertebral disc regeneration, dentritic stem cell vaccines regarding brain tumours, trigeminal neuralgia, aneurysm surgery, etc. Among his achievements are the prediction of neural and anatomical abnormalities of the gastrointestinal system resulting from contusion SCI and functional multipotency of NSCs- its therapeutic implications- in USA. 

In addition to his scientific interests, he is the President of Society of Stem Cell and Cellular Therapies in Turkey. He is also member of AANS, CNS, Society of Neuroscience, Turkish Neurosurgical Society, Society of Nervous System Surgery and Turkish Spine Society. He is the chief editor of Journal of Nervous System Surgery. He had been teaching neurosurgery to medical students at the Baskent University, Turkey from 2008 to 2013. Between 2013 to 2015, he was the chief of Neurosurgery Department in Private Reyap Hospital, Tekirdağ. Curently, he has been the chief of Department of Neurosurgery in University of Health Sciences Turkey, Gaziosmanpaşa Training and Research Hospital, Istanbul, Turkey since 2016. He was awarded as the first candidate for Specialization Thesis (2004) and Board Exam (2011) in Turkey, respectively. He was also awarded as research project regarding Stem Cell Applications in Rat Model (2013) in Turkey. He has more than 100 publications in peer-reviewed international journals with around 1300 citations. His h-index is 21 in google scholar and 17 in web of science. 

Selected Publications: 

1. S.Kabatas, D.Yu, X.D.He, H.S.Thatte, D.Benedict, K.T.Hepgul, P.M.Black, S.Sabharwal, Y.D.Teng, “Neural and anatomical abnormalities of the gastrointestinal system resulting from contusion spinal cord injury.“ Neuroscience 154(4): 1627-1638 pp., 2008 

2. Y.D.Teng, S.Kabatas, J.Li, D.R.Wakeman, E.Y.Snyder, R.L.Sidman, “Functional Multipotency of Neural Stem Cells and Its Therapeutic Implications“, ed. H.Ulrich. Perspectives of Stem Cells, 255-270 pp., Springer Dordrecht Heidelberg London New York © Springer Science+Business Media B.V., 2010 

4. S.Kabatas, Y.D.Teng, “Potential Roles of Neural Stem Cell in Restoration of the Injured Spinal Cord: Review of the Literature.“ Turk Neurosurg 20(2): 103-110 pp., 2010 

5. S. Kabataş, T. Cansever, E. Civelek, C. Yılmaz, "The therapeutic potential of neural stem cells in traumatic brain injuries", Curr Signal Transd T 6(3): 327-336 pp., 2011 

6. Teng YD, Yu D, Ropper AE, Li J, Kabatas S, Wakeman DR, Wang J, Sullivan MP, Redmond DE Jr, Langer R, Snyder EY, Sidman RL. Functional multipotency of stem cells: a conceptual review of neurotrophic factor-based evidence and its role in translational research. Curr Neuropharmacol 9(4): 574-85, 2011. 

7. Karaoz E, Kabatas S, Duruksu G, Okcu A, Subası C, Ay B, Musluman M, Civelek E. Reduction of lesion in injured rat spinal cord and partial functional recovery of motility after bone marrow derived mesenchymal stem cell transplantation. Turk Neurosurg 22(2): 207-17, 2012. 

8. Han I-B, Kim S-W, Ropper AE, Thakor D, Kabatas S, Teng YD. Recent Patents on Cell-based Approaches for Intervertebral Disc Regeneration. Recent Patents on Biomedical Engineering, 5: 122-30, 2012 

9. Sonmez E, Kabatas S, Ozen O, Karabay G, Turkoglu S, Ogus E, Yilmaz C, Caner H, Altinors N. Minocycline Treatment Inhibits Lipid Peroxidation, Preserves Spinal Cord Ultrastructure and Improves Functional Outcome after Traumatic Spinal Cord Injury in the Rat . Spine (Phila Pa 1976). 2013 Jan 30.

10. Han I-B, Ropper AE, Konya D, Kabatas S, Toktas Z, Aljuboori Z, Chi JH, Teng YD. Biological Approaches to Treating Intervertebral Disc Degeneration: Devising stem cell therapies. Cell Transplant 24 (11): 2197-208, 2015. 

11. Aras Y, Sabancı PA, Kabataş S, Duruksu G, Subaşı C, Erguven M, Karaöz E. The Effects of Adipose Tissue-Derived Mesenchymal Stem Cell Transplantation During The Acute And Subacute Phases Following Spinal Cord Injury. Turk Neurosurg 26 (1):127-39, 2016.

12. Kabatas S, Demir CS, Civelek E, Yilmaz I, Kircelli A, Yilmaz C, Akyuva Y, Karaoz E. Neuronal regeneration in injured rat spinal cord after human

dental pulp derived neural crest stem cell transplantation. Bratisl Med J 119 (3): 143-151, 2018

13. Karaoz E, Tepekoy F, Yilmaz I, Subasi C, Kabatas S. Reduction of Inflammation and Enhancement of Motility after Pancreatic Islet Derived Stem Cell Transplantation Following Spinal Cord Injury. J Korean Neurosurg Soc. 2019 Mar;62(2):153-165. 

14. Han IB, Thakor DK, Ropper AE, Yu D, Wang L, Kabatas S, Zeng X, Kim SW, Zafonte RD, Teng YD. Physical impacts of PLGA scaffolding on hMSCs: Recovery neurobiology insight for implant design to treat spinal cord injury.

Exp Neurol. 2019 Oct;320:112980. 

15. Kabataş S, Cİvelek E, Sezen GB, Kaplan N, Savrunlu EC, Çetİn E, Dİren F, KaraÖz E. Functional Recovery after Wharton's Jelly-Derived Mesenchymal Stem Cell Administration in a Patient with Traumatic Brain Injury: A Pilot Study. Turk Neurosurg. 2020;30(6):914-922. 

16. Kabataş S, Civelek E, İnci Ç, Yalçınkaya EY, Günel G, Kır G, Albayrak E, Öztürk E, Adaş G, Karaöz E. Wharton's Jelly-Derived Mesenchymal Stem Cell Transplantation in a Patient with Hypoxic-Ischemic Encephalopathy: A Pilot Study. Cell Transplant. 2018 Oct;27(10):1425-1433. 

17. Teng YD, Wang L, Kabatas S, Ulrich H, Zafonte RD. Cancer Stem Cells or Tumor Survival Cells? Stem Cells Dev. 2018 Nov 1;27(21):1466-1478. 

18. Kabatas S, Civelek E, Savrunlu EC, Kaplan N, Boyalı O, Diren F, Can H, Genç A, Akkoç T, Karaöz E. Feasibility of allogeneic mesenchymal stem cells in pediatric hypoxic-ischemic encephalopathy: Phase I study. World J Stem Cells. 2021 May 26;13(5):470-484. 

19. Kabataş S, Civelek E, Kaplan N, Savrunlu EC, Sezen GB, Chasan M, Can H, Genç A, Akyuva Y, Boyalı O, Diren F, Karaoz E. Phase I study on the safety and preliminary efficacy of allogeneic mesenchymal stem cells in hypoxic-ischemic encephalopathy. World J Exp Med. 2021 Mar 20;11(2):17-29.