Page 43 - Treatment in Istanbul (Turkey)

Specialised in oral and maxillofacial surgery

Graduated from Okan University faculty of dentistry Istanbul (Prosthodontics Department)

Master degree in Dental surgery DDS Okan university

Specialised in oral and maxillofacial surgery from Okan University Istanbul.

He holds the Turkish board from the Turkish Ministry of health.

8 Years experience in the field of oral and maxillofacial surgery and cosmetic dentistry.

5 Years experience in the field of medical tourism.

Languages :

Arabic 

English 

Turkish 

MEDICAL INTEREST 

Face lift 

Body shaping 

Brazilian butt aesthetics 

Breast aesthetics 

Breast reconstruction 

Reconstructive and microsurgical operations

Education 

Istanbul University Cerrahpasa Faculty of Medicine - 2015 

Necmettin Erbakan University Meram Faculty of Medicine - 2021 

Experience 

Health Sciences University, Başakşehir Çam and Sakura City Hospital, Plastic, Reconstructive and Aesthetic Surgery 2021- 2023 

Haliç University Medical Faculty, Department of Plastic, Reconstructive and Aesthetic Surgery 2022 

Necmettin Erbakan University, Meram Faculty of Medicine, Plastic, Reconstructive and Aesthetic Surgery 2016 - 2021 

Kars Digor State Hospital 2015 - 2016

Liv Hospital Ulus

Medical Interests and Activities 

Cardiac Rhythm Disorders 

Pacemaker Implantations 

Electrophsiology and Catheter Ablation 

Atrial Fibrilation Atration 

Resynchronisation Therapy (Pacemaker) for Heart Failure 

Coronary Artery Interventional Therapies (Angiography, Balon – Stent Procedures)

Education and Experience 

Department of Cardiology, Liv Hospital, Ulus 

Department of Cardiology, Anadolu Health Center 

Department of Electrophysiology, University of Leipzig – Heart Center, Germany • Siyami Ersek Cardiovascular Surgery Center 

Faculty of Medicine, İstanbul University Memberships • Turkish Society of Cardiology 

European Society of Cardiology

Memberships 

Turkish Society of Cardiology 

European Society of Cardiology 

Researches and Publications 

International: 16 

National: 20

Book Chapters: 4

1995-2001 Konya Selçuk University Faculty of Medicine,

2002-2008 Ankara Gazi University Faculty of Medicine Chest Diseases Specialization Training,  

2008-2012 Chest Diseases Specialist at Şanlıurfa Mehmet Akif İnan Training and Research Hospital  

Gebze Fatih State Hospital between 2012-2024

2024 Büyük Anadolu Hospital Chest Diseases Specialist

I have experience in COPD, Asthma, Allergic Diseases, Pneumonia, Lung Cancer, Occupational Lung Diseases, Covid-19 Related Diseases, Pulmonary Tuberculosis, Bronchoscopy, intensive care, and sleep disorders.

Specializations

Hypertension

Cardiovascular Occlusion and Treatment

Heart Failure Diagnosis and Treatment

Heart Rhythm Disorders

High Cholesterol

Congenital Heart disease

Education

2009-2015 Azerbaijan Medical University Faculty of Medicine

2017 -2023 Kocaeli University Faculty of Medicine Cardiology Specialization Training

Specialties

Kidney and urinary tract endoscopic stone crushing treatment

Endoscopic Prostate and Bladder Surgery (TUR Method)

Diagnosis and surgery of testicular diseases

Diagnosis and treatment of infertility in men (Varicocele surgeries)

Diagnosis and treatment of sexual dysfunctions

Treatment of urinary incontinence in women

Treatment of nocturnal incontinence in children

Treatment of undescended testicle in children

Circumcision

Experience

1995-1999 Bilecik State Hospital Urology Clinic

1999-2002 Kocaeli Gölcük State Hospital Urology Clinic

2002-2006 Sakarya Karasu State Hospital Urology Clinic and Chief Physician

2006-2012 Kocaeli State Hospital Urology Clinic and Chief Physician

2012-2015 Kocaeli State Hospital Urology Clinic

2015-2018 Kocaeli Public Hospitals Secretary General

2018-2021 Kocaeli Provincial Health Director

2021-2023 Kocaeli Darıca Farabi Training and Research Hospital Urology Clinic

2023- 2024 Kocaeli Gölcük Necati Çelik State Hospital Urology Clinic

2024 Private Darıca Büyük Anadolu Hospital

Education

Uludag University Faculty of Medicine (graduation) 1988

Selcuk University Faculty of Medicine (specialization) 1994

1982-1988 Uludağ University Faculty of Medicine

1990 -1994 Selcuk University Faculty of Medicine, Department of Urology (Specialization)

Scientific Publications

Acar A., Sert I. Ü., Gürbüz R., Ergüney Ş: Submucosal methotrexate applications in inoperable bladder tumors.  S.Ü.T.F. Journal. 1993; 9(1):39-41

Acar A., Sert İ.Ü., Gürbüz R., Arslan E.M., Ergüney Ş. , : Bladder wall and prostate

Translated with DeepL.com (free version)

Experience

Hospitalpark Darıca Hospital

Sultanbeyli State Hospital

Yesilyurt State Hospital

Edirne Health Center No. 4

Education

Selçuk University Faculty of Medicine (1989)

Istanbul Göztepe Training and Research Hospital

Vocational Trainings, Courses and Conferences Attended

Marmara University Istanbul Pediatric Orthopedic Meetings "Sipina Bifida" Symposium

Turkish Neurosurgery Association Cervical Disc Herniation Course

Turkish Neurosurgery Association "Spinal Surgery and Peripheral Nerve Surgery" Training Course

Turkish Neurosurgery Association "Cerebrovascular Surgery" Training Course

Turkish Neurosurgery Association "Head Traumas, Pain Management and Functional Neurosurgery" Training Course

TCDD "Preventive Medicine" Course

Turkish Neurosurgery Association "12th Scientific Congress" Antalya

Turkish Neurosurgery Association "13th Scientific Congress" Istanbul

Turkish Neurosurgery Association Course on "Tumors"

Professional Memberships

Turkish Neurosurgery Association

Turkish Medical Association

Specializations

Diabetes (Sugar)

Thyroid

Hypertension

cholesterol

stomach diseases

intestinal diseases

osteoporosis

Experience

Azerbaijan Gusar Central Hospital

Vreden Russian Research Institute of Traumatology and Orthopedics

Azerbaijan Göranboy, First Lieutenant Doctor

Hospital Park Darıca Hospital

BAH

Education

Azerbaijan Medical Faculty (2015)

Kocaeli Derince Training and Research Hospital (2016-2020)

Vocational Trainings, Courses and Conferences Attended

Internal Medicine Congress

Gastro Academy

Education:

• Degree: Faculty of Medicine, Trakya University, 2009
• Medical Specialty: Internal Medicine, Bakırköy Dr. Sadi Konuk Training and Research Hospital, 2010-2014
• Specialist Doctor: Internal Medicine, Kanuni Sultan Süleyman Training and Research Hospital, 2014-2019
• Specialist Doctor: Internal Medicine, Turkish Hospital Internal Medicine Clinic, Qatar, 2019-2020
• Specialist Doctor: Internal Medicine, Istanbul Medipol University Hospital Mega Hospital Internal Medicine Department, 2020-2024
• Associate Professor Doctor: Internal Medicine, Istanbul Medipol University Medipol Acıbadem Regional Hospital, 2024-Present.

Roles in Projects:

Sub investigator (Assistant Researcher) in the SOUL Study: Cardiovascular Outcome Research of Semaglutide in Type 2 Diabetic Patients, approved by the Turkish Medicines and Medical Devices Agency on May 22, 2019.

Sub investigator (Assistant Researcher) in the international study “SCALE™ Insulin”: Efficacy and Safety of Liraglutide 3.0 mg in Overweight or Obese Patients with Type 2 Diabetes Treated with Basal Insulin (Study Code: NN8022-4272), conducted by Novo Nordisk A.Ş.

Subinvestigator (Assistant Researcher) in the international study NN5401-4266 StepByStep Intensification conducted by Novo Nordisk.

Assistant Researcher in the study "A Research Study to Compare Semaglutide to Insulin Aspart, When Taken Together With Metformin and Insulin Glargine, in People With Type 2 Diabetes (SUSTAIN 11)" (2019-2020).

Assistant Researcher in the PIONEER 1 study: Randomized Clinical Trial of the Efficacy and Safety of Oral Semaglutide Monotherapy in Comparison With Placebo in Patients With Type 2 Diabetes.

Specializations

• Rhinoplasty Aesthetics
• Facial Applications in Surgery
• Breast Aesthetics
• Body Shaping Aesthetics
• Liposuction
• Botox-Filler-Mesotherapy Procedures

 Medical Experience

- *2023 - Present*: Memorial Şişli Hospital  

 Neurosurgery Specialist / Istanbul

- *2013 - 2023*: Bezmialem University Faculty of Medicine  

 Neurosurgery Specialist / Istanbul

- *2011 - 2013*: Konya Beyşehir State Hospital  

 Neurosurgery Specialist / Konya

- *2010 - 2011*: Bezmialem University Faculty of Medicine  

 Research Assistant in Brain and Nerve Surgery / Istanbul

 Medical Education

- *2021 - 2023*: Bezmialem Vakif University Faculty of Medicine  

 / Istanbul / Turkey

- *2006 - 2011*: Bezmialem Vakif University Faculty of Medicine  

 / Istanbul / Turkey

- *2000 - 2006*: Istanbul University Cerrahpasa Faculty of Medicine  

 / Istanbul / Turkey

ACADEMIC CAREER SUMMARY

Degree: Bachelor's
Field: Medicine
University: Atatürk University
Year: 2001

Degree: Master's
Field: Medicine
University: Atatürk University
Year: 2001

Specialization/Doctorate: Internal Medicine/Gastroenterology
University: İnönü University
Year: 2012

Associate Professorship: Gastroenterology
University: İnönü University
Year: 2018

Foreign Language: English, 67.5, 2007

H-index (WoS/Google): 8/10

Impact Factor: 8.1577

Key Research Work:
“Does apocynin increase liver regeneration in the partial hepatectomy model?” Yılmaz Bilgiç, Burhan Hakan Kanat, Onural ÖZHAN, Azibe YILDIZ, Zeynep AKSUNGUR, Mehmet Erman ERDEMLİ, Nigar VARDI, Yusuf TÜRKÖZ, Sami AKBULUT, Adem KÖSE, Hakan PARLAKPINAR. Turkish Journal of Medical Sciences, 2023 (53), 1-12 Q3.

Declared Project Title, Year:
K.3.6. “Investigation of the Effects of Vinpocetine in Sepsis Created by Cecal Ligation and Puncture in Rats” (Principal Investigator), 2023

International Experience:
Advanced Endoscopy Training, Anam Hospital, South Korea (3 months, 2016)
Advanced ERCP Course, Olympus Training Center, Hamburg (2017)

ADMINISTRATIVE POSITIONS

• Institution: İnönü University Turgut Özal Medical Center
  City: Malatya
  Position: Assistant Chief Physician
  Period: 2021 - 2024

Hair Transplant Surgeon, MD. Medical Aesthetic Physician

Dr. Ali Osman SOLUK is a successful hair transplant surgeon who works at Smile Hair Clinic, sharing his experience in hair transplantation and treatment with patients and guiding them. Dr. Ali Osman SOLUK, who graduated from Istanbul Faculty of Medicine, started his medical career in Istanbul Metropolitan Municipality, where he worked as a field physician in Home Health Services and as a senior manager in ISPER, one of the companies of Istanbul Metropolitan Municipality, for a long time. During this time, he contributed as a manager in the execution of most of the health services provided to Istanbulites by the municipality.

During this period, he participated in many national and international fairs and many international meetings with UCLG Health Committee for the development of health tourism in Turkey and the promotion of the country.

Candan Cantaş was born in Sivas in 1996 and completed her primary and secondary education there. She successfully completed her high school education at Prof. Dr. Necati Ersen Anatolian Teacher Training High School, where she was also awarded. In 2014, she started her 5-year dental education at the Faculty of Dentistry at Cumhuriyet University, and completed it in 2019. She started working as a dentist in the same year, and currently works at Istanbul Dental. Candan aims to provide the best treatment to her patients by using up-to-date knowledge and techniques in her field of expertise. She is also determined to have a successful career by focusing on continuous professional development.

Adem Demiral, a Hair Transplant Expert, was born in Ordu in 1980. He specializes in hair transplant applications and holds expertise in health institutions management and management, as well as various aspects of hair transplantation including supportive treatment applications, dermocosmetic and care products, necrosis treatment, GETAT applications, new technologies, and tissue transplantation research. Additionally, he is skilled in emergency case management and incident scene management in extraordinary situations. Adem Demiral pursued his education in First and Emergency Aid Technician (Paramedic) at Kadir Has University in 2000, and later obtained a degree in Health Management from Istanbul University AUZEF in 2019. He also holds an International Hair Transplantation Practitioner Certification Training from Euro Passcard. 

Training and Expertise 

1998 - Prof.Dr.Schakar (Presbiopia Surgery, Forthworth - Texas) 

1990 - Fyodorov Eye Hospital (Refraction Surgery, Moscow) 

1988 - Prof. Dr. Kerin (Vitreo-Retinal Surgery, Duisburg 

1982 - SSK Ankara Dışkapı Hospital (Ophthalmology Specialist) 

1978 - Hacettepe University Faculty of Medicine (Medical Doctor) 

Experience 

VM Medical Park Pendik Hospital, Istanbul 2017 - Still 

Eye Clinic Chief, Beyoğlu Kuledibi Eye EAH (2001-2004) 

Eye Clinic Chief Şişli EAH (1999-2001) II. 

Eye Clinic Chief, Kartal EAH (1995-1999) II. 

Eye Clinic Chief-Chief Physician, Kartal EAH (1993-1994) 

Chief Physician, Kartal Training and Research Hospital, 1st Eye Clinic (1992-1993) 

Conductor-Chief Physician Beyoğlu Kuledibi EAH (1987-1991) 

Başasistan, Beyoğlu Kuledibi Training and Research Hospital Eye Clinic (1986-1987) 

Uzm.Dr.-Başhekim, Nevşehir State Hospital (1982-1985) 

Professional Memberships 

Turkish Ophthalmology Association 

American Academy Ophthalmology 

ESCRS 

Big Club 

Heybeliada Water Sports Club 

125 publications including 27 oversea

AREAS OF INTEREST: 

 Micro surgery 

 Skin tumors 

 wound care 

 Rhinoplasty 

 Liposuction 

 Breast aesthetics 

 Tummy tuck 

 Face lift 

Education and Expertise 

2007-2013 Istanbul University Istanbul Faculty of Medicine– Medical education 

2013-2019 - Health Sciences University Şişli Etfal Training and Research Hospital-Specialization Experience 

2013 January-2019 March-Health Sciences University Şişli Etfal Training and Research Hospital Plastic, Reconstructive and Aesthetic Surgery Clinic, Istanbul -Assistant 

2019 March-2019 April Health Sciences University Şişli Etfal Training and Research Hospital Plastic, Reconstructive and Aesthetic Surgery Clinic, Istanbul -Specialist

2019 June-2021 July Yalova State Hospital Plastic, Reconstructive and Aesthetic Surgery Clinic, Yalova-Expert

Courses and Certificates 

Euorepan Board Certifcate EBOPRAS (European board Certificate)-2020 

Turkish Board Certifcate (Turkish Plastic Surgery Association Board Certificate)-2020 

II. Marmara Region Plastic Surgery Training Meeting - 2014 

22. Basic Microsurgery Course - 2014 

37. Turkish Plastic, Reconstructive and Aesthetic Surgery Association National Congress -2015 

12.Cerrahpaşa Plastic Surgery Days 'Breast Reconstruction' - 2015 

I. Plastic Surgery Assistant Basic Training Course -2016 

39. Turkish Plastic, Reconstructive and Aesthetic Surgery Association National Congress - 2017 

I. Obesity Surgery Symposium - 2018 

Bezmialem Vakıf University Experimental Animal Use Certificate Training - 2018 

ISAPS Course – TURKEY 10th Eurasian International Aesthetic Course with Live Surgeries - 2018 

Preservation Rhinoplasty Course - 2018

Professional Memberships 

Turkish Plastic, Reconstructive and Aesthetic Surgery Association

Dr. Ayan graduated from Medical School in 1991 and completed his urology education in 1997. At the beginning of his carrier, he was a post doctorate research fellow at the Department of Urology of Harvard Medical School, Children’s Hospital in Boston (1999-2000). He studied the effect of partial ureteral obstruction to the kidney in early developmental stage in an experimental animal fetus model. This study provided a significant contribution to a complicated issue of pediatric urology and was cited many times by its successors. 

He became associate professor of urology in 2004 and was appointed as a professor of urology in 2009. He was accepted as a clinical fellow in Minimal Invasive Urologic Oncology at the Department of Surgery, Section of Urology at the University of Chicago (2014-2015). He worked in an intense oncology program mainly concentrated on robotic surgery of prostate and kidney cancer. Because of this background, he is mainly interested in urologic oncology and pediatric urology. The primary portion of his daily practice consist of kidney cancer, prostate cancer, bladder cancer, neonatal hydronephrosis, ureteropelvic junction obstruction, urine reflux to kidney, hypospadias and undescended testis. 

Because of its prevalence in Turkey, Prof. Ayan has a huge experience with urinary stone disease and he is doing large number of endoscopic and percutaneous surgeries for kidney, ureter and bladder stones. 

Prof. Ayan holds United States Medical License and European Board of Urology Certificate. He is a member of AUA, EAU and Turkish Urologic Surgery and Urologic Oncology Societies. 

List of International Scientific Publications; 

1. Ayan S, Yildirim S, Ucar C, Sarioglu Y, Gültekin EY, Butuner C. Corporal reactivity to adenosine and prostaglandin E1 in alloxan-induced diabetic rabbit corpus cavernosum and the effect of insulin therapy. BJU Int, 83: 108-12, 1999. 

2. Yildirim S, Ayan S, Sarioglu Y, Gültekin EY, Butuner C. The effects of long-term oral administration of L-arginine on the erectile response of rabbits with alloxan-induced diabetes. BJU Int, 83: 679-85, 1999. 

3. Ayan S, Kaloglu C, Gökce G, Kılıcarslan H, Gültekin EY. Effect of insulin therapy to diabetic cystopathy: urodynamic and histological findings in a rabbit model. Sc J Urol Nephrol, 33: 392-5, 1999. 

4. Yildirim S, Ayan S, Sarioglu Y, Gültekin Y, Uma S. Does diabetes mellitus affect the progress of tolerance to isosorbide dinitrate (ISDN) in corporal tissue? Nitric Oxide: Biology and Chemistry, 4: 29- 34, 2000. 

5. Ayan S, Sarioglu Y, Yildirim S, Gokce G, Bagcıvan I. Relaxation induced by omeprazole does not change in diabetic rabbit corpus cavernosum. BJU Int, 87(3):265-8, 2001. 

6. Ayan S, Gokce G, Kılıcarslan H, Kaya K, Gultekin EY. An unusual cause of urinary incon tinence: urethral coitus. Sc J Urol Nephrol, 35:254, 2001. 

7. Yildirim S, Simsek R, Ayan S, Gokce G, Sarıoğlu Y, Safak C. Relaxant effect of some benzothiazolinone dervatives on isolated rabbit corpus cavernosum. Urol Res, 29:182-5, 2001. 

8. Ayan S, Roth JA, Freeman MR, Bride SH, Peters C. Partial ureteral obstruction dysregulates the RAS in the fetal sheep. Urology, 58: 301-6, 2001. 

9. Kılıcarslan H, Ayan S, Gokce G, Kaya K, Gultekin EY. Cranial blind ending branch of a bifid ureter. Int Urol Nephrol, 32: 635-6, 2001. 

10. Gokce G, Kılıcarslan H, Ayan S, Yıldız E, Kaya K, Gultekin EY. Adenomatoid tumors of testis and epididym: a report of two cases. Int Urol Nephrol, 32:677-80, 2001. 

11. Ayan S, Gokce G, Kılıcarslan H, Ozdemir O, Yildiz E, Gultekin EY. K-RAS mutation in transitional cell carcinoma of urinary bladder. Int Urol Nephrol, 33:363-67, 2001. 

12. Bulut HE, Onarlıoglu B, Kaloglu C, Özdemir Ö, Ayan S. Effects of experimental diabetes and insulin treatment on rabbit renal morphology: a quantitative and qualitative study. Turk J Med Sci, 31: 209-16, 2001. 

13. Kılıcarslan H, Gokce G, Ayan S, Gultekin EY, Arıkan Y, Hocaoglu S. Fournier’s gangrene: a report of 20 cases. T Klin J Med Res 19:55-58, 2001. 

14. Gokce G, Kılıcarslan H, Ayan S, Tas F, Akar R, Kaya K, Gultekin EY. Genitourinary tuberculosis: A review of 174 cases. Scand J Infect Dis, 34: 338-40, 2002. 

15. Kilicarslan H, Yildirim S, Bagcivan I, Ayan S, Sarac B, Sarioglu Y. Effect of chronic renal failure (CRF) on purinergic responses of corpus cavernosal smooth muscle in rabbits. BJU Int 90(6):596-600, 2002. 

16. Bagcivan I, Gokce G, Ayan S, Yildirim S, Sarac B, Kilicarslan H, Sarioglu Y. Hydrogen-potassium ATPase inhibitors induce relaxation on rabbit prostatic strips in vitro.Int J Urol.;9(11):641-4; discussion 645, 2002. 

17. Bagcivan I, Kilicarslan H, Sarac B, Gokce G, Yildirim S, Ayan S, Sarioglu Y. The evaluation of the effects of renal failure on erectile dysfunction in a chronic renal failure (CRF) rabbit model. BJU Int.;91(7):697-701, 2003 

18. Kilicarslan H, Guvenal T, Ayan S, Gokce G, Cetin A, Gultekin Y. Comparison of outcomes of three different surgical techniques performed for stress urinary incontinence. Int J Urol.;10(3):126- 30, 2003. 

19. Kaya S, Poyraz O, Gökçe G, Kılıçarslan H, Kaya K and Ayan S. Role of Genital Mycoplasmata and Other Bacteria in Urolithiasis. Scand J Infect Dis, 35:315-317,2003. 

20. Kilicarslan H, Gokce G, Ayan S, Atalar M, Kaya S, Kaya K, Gultekin Y. A case of hydatid disease: urinary retention due to isolated retrovesical hydatid cyst in a boy. Scand J Infect Dis, 35 :408-410, 2003. 

21. Gokce G, Kaya K, Kılıcarslan H, Tas F, Ayan S, Yıldız E, Gultekin E Y. Epidermoid cyst in the renal pelvis. Int Urol Nephrol;35(1):9-10, 2003. 

22. Kilicarslan H, Gokce G, Ayan S, Guvenal T, Kaya K, Gultekin EY. Predictors of outcome after in situ anterior vaginal wall sling surgery. Int Urogynecol J Pelvic Floor Dysfunct ;14(5):339-41, 2003. 

23. Kilicarslan H, Gokce G, Kaya K, Ayan S, Gultekin YE. Surgical treatment of penil fractures. Ulus Travma Derg.;9(1):54-6, 2003. 

24. Yildiz E, Gokce G, Kilicarslan H, Ayan S, Goze F, Gultekin EY. Prognostic value of the expression of Ki-67, CD44 and vascular endothelial growth factor, and microvessel invasion, in renal cell carcinoma. BJU Int. 2004 ;93(7):1087-93. 

25. Gokce G, Topsakal K, Ayan S, Kilicarslan H, Gokce SF, Gultekin EY. Case report: Nonobstructive giant urethral stone with two safety pins. Int Urol Nephrol. 2004;36(1):65-6. 

26. Kaya K, Ayan S, Gokce G, Kılıcarslan H, Yildiz E, Gultekin EY. Urinary nuclear matrix protein 22 for diagnosis of renal cell carcinoma. Scand J Urol Nephrol. 38 :1-5,2004. 

27. Ayan S, Kaya K, Topsakal K, Kılıçarslan H, Gokce G, Gültekin Y. Efficacy of tolterodine as a firstline treatment for non-neurogenic voiding dysfunction in children. BJU Int. 96(3):411-4, 2005. 

28. Kaya K, Gokce G , Kaya S, Kilicarslan H, Ayan S, Gultekin EY. Isolated renal and retropertoneal hydatid cysts: a report of 23 cases. Trop Doct. 2006 Oct;36(4):243-6. 

29. Candan F, Ayan S, Tas F, Gokce G, Elagoz S. Spontaneous renal laceration as the presenting feature of polyarteritis nodosa in a patient with familial Mediterranean fever after hepatitis A infection. Rheumatol Int, 25(6):475-7, 2005. 

30. Silig Y, Pinarbasi H, Gunes S, Ayan S, Bagci H, Cetinkaya O. Polymorphisms of CYP1A1, GSTM1, GSTT1, and prostate cancer risk in Turkish population. Cancer Invest, 24(1):41-5, 2006. 

31. Tanzer F, Ozgur A, Bardakci F, Cankorkmaz L, Ayan S. Analysis of a 1-year-old cystinuric patient with recurrent renal stones. Int J Urol. 13(10):1347-9, 2006. 

32. Kilicarslan H, Ayan S, Vuruskan H, Gokce G, Gultekin EY.Treatment of detrusor sphincter dyssynergia with baclofen and doxazosin. Int Urol Nephrol. 2006;38(3-4):537-41. 

33. Ayan S, Topsakal K, Gokce G, Gultekin EY.Efficacy of combined anticholinergic treatment and behavioral modification as a first line treatment for nonneurogenic and nonanatomical voiding dysfunction in children: a randomized controlled trial. J Urol. 2007 Jun;177(6):2325-8; discussion 2328-9. 

34. Ozdemir O, Gul E, Kilicarslan H, Gokce G, Beyaztas FY, Ayan S, Sezgin I.SRY and AZF gene variation in male infertility: a cytogenetic and molecular approach. Int Urol Nephrol. 2007;39(4):1183-9. 

35. Yildiz E, Ayan S, Goze F, Gokce G, Gultekin EY. Relation of microvessel density with microvascular invasion, metastasis and prognosis in renal cell carcinoma. BJU Int. 2008 Mar;101(6):758-64. 

36. Kenan Kaygusuz, Gokhan Gokce, Iclal Ozdemir Kol, Semih Ayan and Sinan Gursoy. Efficacy of Preventive Analgesia with Tramadol or Lornoxicam for Percutaneous Nephrolithotomy: A Prospective, Randomized, Double-Blind, Placebo-Controlled Study. Current Therapeutic Research 68(4), 205-216, 2007. 

37. Kaygusuz K, Gokce G, Gursoy S, Ayan S, Mimaroglu C, Gultekin Y.A comparison of sedation with dexmedetomidine or propofol during shockwave lithotripsy: a randomized controlled trial. Anesth Analg. 2008 Jan;106(1):114-9. 

38. Gokce G, Karboga H, Yildiz E, Ayan S, Gultekin Y. Effect of angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade on apoptotic changes in contralateral testis following unilateral testicular torsion. Int Urol Nephrol. 2008;40(4):989-95. 

39. Ozdemir, O (Ozdemir, Oztuerk); Yildiz, E (Yildiz, Esin); Ayan, S (Ayan, Semih); Gul, E (Gul, Eylem)1; Gokce, G (Gokce, Goekhan); Yildiz, F (Yildiz, Fazilet)1; Koksal, B (Koksal, Binnur)1; Goze, F (Goze, Fahrettin); Gultekin, EY (Gultekin, E. Yener). Epigenetic alterations and oncogenes mutations in urinary bladder carcinomas.CHROMOSOME RESEARCH. 2009, Volume: 17 Supplement: 1 Pages: 171-171 

40. Eskicorapci SY, Türkeri L, Karabulut E, Cal C, Akpinar H, Baltaci S, Baykal K; Turkish Validation Study Group of Kattan Preoperative Nomogram, Kattan MW, Ozen H. Collaborators: Yildirim A, Yazici S, Divrik RT, Ozkardeş H, Koşan M, Kurtuluş FO, Büyükalpelli R, Mungan A, Lekili M, Sahin H, Günlüsoy B, Ayan S, Bozlu M. Validation of two preoperative Kattan nomograms predicting recurrence after radical prostatectomy for localized prostate cancer in Turkey: a multicenter study of the Urooncology Society. Urology. 2009 Dec;74(6):1289-95. 

41. Ozdemir O, Yildiz S, Ayan S, Gül E, Gokce G, Yildiz F, Koksal B. Promoter hypermethylation of tissue specific tumor supressor genes and point mutation in K-ras, c-myc proto-oncogenes in urinary (transitional cell) bladder carcinoma. Health. 2010; 2(8):850-856. 

42. Türkeri L, Tanıdır Y, Çal Ç, Özen H, Şahin H; Collaborators :Kaya C, Karaman İ, Şengör F, Alkibay T, Sözen S, Büyükalpelli R, Can C, Kuyumcuoğlu U, Albayrak S, Abay E, Soyupak B, Tansuğ Z, Fazlıoğlu A, Gültekin Y, Ayan S, Gümüş E, Lekili M, Dillioğlugil Ö, Özer G, Uygur C, Akpınar H. Comparison of the efficacy of single or double intravesical epirubicin instillation in the early postoperative period to prevent recurrences in non-muscle-invasive urothelial carcinoma of the bladder: prospective, randomized multicenter study. Urol Int. 2010;85(3):261-5. 

43. Kuzgunbay B, Yaycioglu O, Soyupak B, Atay Kayis A, Ayan S, Yavascaoglu I, Cal C, Beduk Y; Turkish Study Group of Public Awareness in Testicular Cancer Public awareness of testicular cancer and self-examination in Turkey: A multicenter study of Turkish Urooncology Society.Urol Oncol. 2011 Mar 22. Epub ahead of print] 

44. Biçer H, Korgali E, Gökçe G, Ayan S, Yıldırım S, Gültekin EY. Contractile responses of urinary bladder in an experimental model of chronic renal failure. Bosn J Basic Med Sci. 2012 Nov;12(4):219- 23. 

45. Yaycioglu O, Eskicorapci S, Karabulut E, Soyupak B, Gogus C, Divrik T, Turkeri L, Yazici S, Ozen H; Society of Urooncology Study Group for Kidney Cancer Prognosis. A preoperative prognostic model predicting recurrence-free survival for patients with kidney cancer. Jpn J Clin Oncol. 2013 Jan;43(1):63-8. 

46. Erden Y, Korgalı E, Dundar G, Ayan S, Gokce G, Yildirim S, Gultekin EY. In-vitro effects of PDE5 inhibitor and statin treatment on the contractile responses of experimental MetS rabbit's cavernous smooth muscle. Arch Ital Urol Androl. 2014 Mar 28;86(1):33-8.

Cardiology Department 

Education and Specialty: 

2003 - Medical Education, School of Medicine, Çukurova University 

2009 – Specialty, School of Medicine, Uludağ University 

2015- Associate Professor, Adana Training and Research Hospital 

Experience: 

2012 - 2015 – Head of Educational and Administrative Affairs, ENT Clinic, Haseki Training and Research Hospital (3 years) 

2009 – 2011, Conscription, Şevket Yılmaz Training and Research Hospital, Bursa 

2011-2013 Bursa State Hospital 

2013-2015 Seyhan Practice Hospital, Adana Training and Research Hospital 

2015-2016 Head of Department of Cardiology, Okmeydanı Training and Research Hospital 

February 2016 – July 2019, Head of Department of Cardiology, School of Medicine, Biruni University. 

Fields of Specialties: 

Complex Coronary Interventions 

Complex Peripheral Interventions 

Pacemaker Procedures 

Electrophysiological Study and Ablation 

Heart Valve Interventions (TAVI, Mitraclip, Mitral Balloon) 

Certificates: 

Board Certificate, European Society of Cardiology 

Board Certificate, Turkish Society of Cardiology 

Professional Memberships- Number Insignificant: 

1. European Society of Cardiology 

2. Turkish Society of Cardiology 

3. Member of Istanbul Medical Chamber 

Personal motto: Your heart is entrusted to us 

Researches and Articles: 

Articles published in international peer-review journals: 

1. *Uçar H*, Gür M, Koyunsever NY, Seker T, Türkoglu C, Kaypakli O, Sahin DY, Elbasan Z, Cayli M. Mean platelet volume is independently associated with renal dysfunction in stable coronary artery disease. Platelets (ISI). 2013 Jun; 25(4):274-278. doi: 10.3109/09537104.2013.805406. Epub 2013 Jun 17 

A2. *Uçar H*, Gür M, Yildirim A, Börekçi A, Gözükara MY, Seker T, Kaypakli O, Türkoglu C, Ozaltun B, Akyol S, Harbalioglu H, Sahin DY, Elbasan Z, Cayli M. Increased Aortic Stiffness Predicts Contrast-Induced Nephropathy in Patients With Stable Coronary Artery Disease Undergoing Percutaneous Coronary Intervention. Angiology (ISI). 2014 Oct;65(9):806-11. doi: 10.1177/0003319713504126. Epub 2013 Sep 26. 

A3. *Uçar H*, Gür M, Kivrak A, Koyunsever NY, Seker T, Akilli RE, Türkoglu C, Kaypakli O, Sahin DY, Elbasan Z, Tanboga HI, Cayli M. High-sensitivity cardiac troponin T levels in newly diagnosed hypertensive patients with different left ventricle geometry. Blood Pressure (ISI). 2014 Aug;23(4):240-7. doi: 10.3109/08037051.2013.840429. Epub 2013 Sep 23. 

A4. *Uçar H*, Mustafa Gür M, Gözükara MY, Kıvrak A, Kolcu Z, Akyol S, Kaypaklı O, Elbasan Z, Sahin DY, Türkoglu C, Seker T, Çaylı M. Relationship between mean platelet volume and morning blood pressure surge in newly diagnosed hypertensive patients. The Anatolian Journal of Cardiology (ISI). 2014 Apr 8. doi: 10.5152/akd.2014.5196. [Epub ahead of print]. 

A5. *Uçar H*, Gür M, Seker T, Kaypaklı O, Elbasan Z, Koyunsever NY, Türkoglu C, Özaltun B, Kuloglu O, Kalkan GY, Sahin DY, Çaylı M. High-Sensitivity Cardiac Troponin T is Associated with SYNTAX Score and Diabetes Mellitus in Patients with Stable Coronary Artery Disease. Journal of Clinical & Experimental Cardiology , 2013 Jun; 4(9):1-5. doi: 10.4172/2155-9880.1000263 

A6. *Uçar H*, Gür M, Gözükara MY, Kalkan GY, Baykan AO, Türkoğlu C, Kaypakl O, Seker T, Sen O, Selek S, Cayl M. Gamma glutamyl transferase activity is Independently associated with oxidative stress rather than SYNTAX score. Scand J Clin Lab Invest (ISI). 2014 Sep 2:1-6. [Epub ahead of print] 

A7. *Uçar H*, Gür M, Börrekçi A, Yıldırım A, Baykan AO, Kalkan GY,Koç M, Şeker T, Coşkun M, Şen Ö, Çaylı M. Relationship between extent and complexity of coronary artery disease and different left ventricular geometric patterns in patients with coronary artery disease and hypertension. The Anatolian Journal of Cardiology (ISI). DOI:10.5152/akd.2014.5747 

A8. Çaylı M, Elbasan Z, Gür M, Şeker T, *Uçar H*, Kuloğlu O, Şen O, Şahin DY, Yüksel Kalkan G. Modified flower petal technique in the treatment of isolated ostial left main and non-left main bifurcation lesions. Eurointervention. Accepted 2014 Oct. 20140324-02-R2 

A9. Baykan AO, Yüksel Kalkan G, Gür M, *Uçar H*, Acele A, Seker T, Sen O, Kaypakli O, Harbalioğlu H, Cayli M. Coronary Flow Velocity Reserve in Patients with Ascending Aorta Aneurysm. Echocardiography (ISI). 2014 Oct 7. doi: 10.1111/echo.12782. [Epub ahead of print] 

A10. Şeker T, Gür M, *Uçar H*, Türkoğlu C, Baykan AO, Özaltun B, Harbalıoğlu H, Kalkan GY, Kaypaklı O, Kuloğlu O, Şen Ö, Koç M, Çaylı M. Lower serum 25-hydroxyvitamin D level is associated with impaired myocardial performance and left ventricle hypertrophy in newly diagnosed hypertensive patients. The Anatolian Journal of Cardiology (ISI). DOI:10.5152/akd.2014.5637 

A11. Gözükara MY, Börekçi A, Gür M, Aksoy N, Seker T, Kaypaklı O, *Uçar H*, Türkoğlu C, Koç M, Makca I, Akyol S, Selek S, Caylı M. Gamma Glutamyl Transferase Activity is Associated With Both Paraoxonase Activity and Aortic Stiffness in Hypertensive Patients. J Clin Lab Anal (ISI). 2014 Aug 17. doi: 10.1002/jcla.21785. [Epub ahead of print] 

A12. Kalkan GY, Gür M, Baykan AO, *Uçar H*, Elbasan Z, Şahin DY, Koç M, Börekçi A, Çaylı M. Mean platelet volume is associated with aortic intima-media thickness in patients without clinical manifestation of atherosclerotic cardiovascular disease. The Anatolian Journal of Cardiology (ISI). DOI:10.5152/akd.2014.5576 

A13. Gür M, Türkoglu C, Taskın A, *Uçar H*, Börekçi A, Seker T, Gözükara MY, Kaypaklı O, Akyol S, Selek S, Sahin DY, Elbasan Z, Çayli M. Paraoxonase 1 activity and oxidative stress in patients with anterior ST elevation myocardial infarction undergoing primary percutaneous coronary intervention with and without no-reflow. Atherosclerosis (ISI). 2014 Jun;234(2):415-20. doi: 10.1016/j.atherosclerosis.2014.03.005. Epub 2014 Apr 3. 

A14. Sahin DY, Gür M, Elbasan Z, Kırım S, *Uçar H*, Seker T, Kaypaklı O, Uysal OK, Kıvrak A, Koyunsever NY, Akıllı RE, Caylı M. NT-proBNP predicts impaired myocardial function in newly diagnosed hypertensive patients with preserved ejection fraction. Clinical and Experimental Hypertension (ISI). 2014;36(5):289-94. doi: 10.3109/10641963.2013.810234. Epub 2013 Jul 18. 

A15. Caylı M, Gür M, Kalkan GY, Elbasan Z, Sahin DY, Koyunsever NY, Türkoglu C, Seker T, Kaypaklı O, Harbalıoglu H, Uçar. Gamma glutamyl transferase activity: Relationship with thoracic aortic intima media thickness and inflammation. Herz (ISI). 2014 Sep;39(6):761-766. Epub 2013 Aug 11. 

A16. Çaylı M, Gür M, Elbasan Z, Seker T, Türkoglu C, Kaypaklı O, Sahin DY, *Uçar H*, Kıvrak A, Koyunsever NY, Sen Ö. High-sensitivity cardiac troponin T predicts nondipper hypertension in newly diagnosed hypertensive patients. J Clin Hypertens (Greenwich) (ISI). 2013 Oct;15(10):731- 6. doi: 10.1111/jch.12176. Epub 2013 Aug 7. 

A17. Kalkan GY, Gür M, Baykan AO, Koyunsever NY, Kaypakli O, Sen O, Kuloglu O, Seker T, *Uçar H*, Akyol S, Elbasan Z, Sahin DY, Çayli M. Serum bilirubin level and aortic intima-media thickness in patients without clinical manifestation of atherosclerotic cardiovascular disease. Angiology (ISI). 2014 Apr;65(4):308-12. doi: 10.1177/0003319713507627. Epub 2013 Oct 24. 

A18. Gür M, *Uçar H*, Kuloglu O, Kıvrak A, Seker T, Türkoglu C, Ozaltun B, Kaypaklı O, Sahin DY, Elbasan Z, Tanboga HI, Caylı M. Estimated glomerular filtration rate is associated with both arterial stiffness and N-terminal pro-brain natriuretic peptide in newly diagnosed hypertensive patients. Clinical and Experimental Hypertension (ISI). 2014;36(6):374-9. doi: 10.3109/10641963.2013.827703. Epub 2014 Jan 16. 

A19. Gür M, Caylı M, *Uçar H*, Elbasan Z, Sahin DY, Gözükara MY, Selek S, Koyunsever NY, Seker T, Türkoglu C, Kaypaklı O, Aksoy N. Paraoxonase (PON1) activity in patients with subclinical thoracic aortic atherosclerosis. Int J Cardiovasc Imaging (ISI). 2014 Jun;30(5):889-95. doi: 10.1007/s10554-014-0407-y. Epub 2014 Apr 4. 

A20. Budak YU, Huysal K, Polat M, Tarakçi G, *Uçar H*. Evaluation of the Steelex M600H coagulometer prothrombin time-international normalized ratio assay with Steelex test reagents. Biochem Med (Zagreb) (ISI). 2012 Jan; 22: 121-126 pp. 

A21. Seker T, Türkoglu C, *Uçar H*, Gür M, Sahin DY, Caylı M. Treatment of totally occluded aortic coarctation using a covered stent. Herz (ISI). 2014 Mar; DOI: 10.1007/s00059-013-3984-y [Epub ahead of print] 

A22. Börekçi A, Gür M, Türkoğlu C, Çaylı M, Selek S, Kaypaklı O, *Uçar H*, Coskun M, Seker T, Koç M, Gökdeniz T, Gözükara MY. Oxidative Stress and Paraoxonase 1 Activity Predict ContrastInduced Nephropathy in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention. Angiology (ISI). 2014 May; DOI: 10.1177/0003319714533588 [Epub ahead of print] 

A23. Kalkan GY, Gür M, Haydardedeoglu FE , Sinan Kırım S, Baykan AO, Kuloglu O, *Uçar H*, Sahin DY, Elbasan Z, Seker T, Turkoglu C, Yildirim A, Cayli M. The Association between Aortic Distensibility and Coronary Flow Reserve in Newly Diagnosed Diabetic Patients. Echocardiography (ISI). 2014 May; DOI: 10.1111/echo.12631 [Epub ahead of print] 

A24. Kalkan GY, Gür M, Koyunsever NY, Seker T, Gözükara MY, *Uçar H*, Kaypaklı O, Baykan AO, Akyol S, Türkoglu C, Elbasan Z, Sahin DY, Çaylı M. Serum 25-hydroxyvitamin D level and aortic intima-media thickness in patients without clinical manifestation of atherosclerotic cardiovascular disease. Journal of Clinical Laboratory Analysis (ISI). 2014 Aug 17. doi: 10.1002/jcla.21770. [Epub ahead of print]. 

A25. *Uçar H*, Karaagaç K, Serdar OA, Yetkin ZA, Aktürk Y, Karaagaç EU, Sarıcaoglu H, Arterial Elasticity Measurement in Patients with Behçet Disease. HealthMED (2012’ de ISI) 2012 May; 6: 3255-3261 pp. 

A26. Karaagaç K, *Uçar H*, Karaagaç E, Yetkin ZA, Aktürk Y. The Relation Betwen Aspirin Resistance and Mean Platelet Volume in Patients with Significant Coronary Artery Stenosis. HealthMED (2012’ de ISI) 2012 May ;6: 3701-3705 pp. 

A27. Cander S, Coban S Altuner S, Gül ÖÖ, Yetgin ZA, Akkurt A, *Uçar H*, Tuncel E. Prevalence and Correlates of Erectile Dysfunction in Type 2 Diabetes Mellitus: A Cross-Sectional SingleCenter Study Among Turkish Patients. Metabolic Syndrome and Related Disorders (ISI). 2014 Aug;12(6):324-9. doi: 10.1089/met.2013.0150. Epub 2014 Mar 25. 

A28. Abalı G, *Uçar H*, Elbasan Z , Gür M ,Seker T, Koyunsever NY, Çaylı M, Akpınar O. Effect of Statin on Neutrophil to Lymphocyte Ratio in Patients with Coronary Artery Disease. Experimental & Clinical Cardiology (ISI). 2014 May 

A29. Effect of fasting on 24-h blood pressure values of individuals with no previous history of hypertension. Seker A, Demirci H, Ocakoglu G, Aydin U, Ucar H, Yildiz G, Yaman O. Blood Press Monit. 2017 Oct;22(5):247-252. doi: 10.1097/MBP.0000000000000244 

A30. The importance of the neutrophil-to-lymphocyte ratio in patients with hypertrophic cardiomyopathy. Ozyilmaz S, Akgul O, Uyarel H, Pusuroglu H, Gul M, Satilmisoglu MH, Bolat I, Ozyilmaz I, *Uçar H*, Yildirim A, Bakir I. Rev Port Cardiol. 2017 Apr;36(4):239-246. doi: 10.1016/j.repc.2016.09.014. Epub 2017 Mar 18. English, Portuguese 

A31. A case of stent thrombosis presenting as acute myocardial infarction related to right coronary artery originating from the left coronary system. Ermis E, Kahraman S, Ucar H, Allahverdiyev S. Intractable Rare Dis Res. 2018 Feb;7(1):58-60. doi: 10.5582/irdr.2018.01001. 

A32. Triple Coronary Artery Thrombosis Presenting as Acute Anterior ST-Segment Elevation Myocardial Infarction. Ermis E, Kahraman S, Ucar H, Ozyılmaz SO, Allahverdiyev S. Int J Angiol. 2018 Dec;27(4):223-226. doi: 10.1055/s-0037-1608959. Epub 2017 Dec 12 

A33. Relationship between blood pressure variability and cognitive function in geriatric hypertensive patients with well-controlled blood pressure. Yıldırım E, Ermis E, Allahverdiyev S, Ucar H, Yavuzer S, Yavuzer H, Cengiz M. Aging Clin Exp Res. 2019 Feb 1. doi: 10.1007/s40520- 019-01141-6. 

C2. Book chapters written in other languages: 

C2.1. Hung JS, Lau KW, *Uçar H*, Çaylı M, Çaylı M, Practical Handbook: Practical Handbook of Advanced Interventional Cardiology (Inoue balloon mitral valvuloplasty),437-473 pp, Adana / Turkey, Çukurova Nobel Medical Bookstore, 2014 

C2.2. Feldman T, Nguyen TN, *Uçar H*, Çaylı M, Çaylı M, Practical Handbook: Practical Handbook of Advanced Interventional Cardiology (retrograde percutaneous aortic valvuloplasty), 475-486 pp, Çukurova, Adana / Turkey, Çukurova Nobel Medical Bookstore, 2014 

D. Articles published in local peer-review journals: 

D1. *Uçar H*, Gür M, Seker T, Sahin DY, Kalkan GY, Türkoglu C, Yıldırım A, Kaypaklı O, Elbasan Z, Çaylı M. Impaired kidney function is associated with syntax scorein patients with stable coronary artery disease. Archive of Turkish Society of Cardiology, 2014; DOI: 10.5543/tkda.2014.67790 

D2. Kalkan GY, Gür M, Elbasan Z, Baykan AO, Kuloğlu O, Sahin DY, Seker T, Haydardedeoglu FE, Şen Ö, *Uçar H*, Kırım S, Çayli M. Left Ventricle Geometry Affects Coronary Flow Reserve in Diabetic Patients. Archive of Turkish Society of Cardiology, Doi: 10.5543/tkda.2015.59432 

D3. *Uçar H*, Karaagaç K, Tiryakioglu S. Woven Left Coronary Artery: A Case Report. Turkish Clinics Journal of Medical Research-Case Reports 2014 (22), 5-6 pp. 

D4. Albayrak S, Kemal Karaagaç K, Baran I, Yetgin ZA, *Uçar H*, Aydınlar A, "Carvedilol and Metoprolol in Acute Myocardial Infarction Early Effect of Oxidized LDL and Paraoxonase-1 Activity Abant Medical Journal 2013; DOI: 10.5505/abantmedj.2013.30592 

D5. Gür AK, Eker E, Akyol A, Akdag S, Kolcu Z, Odabası D, *Uçar H*. Useage of Intra-aortic Baloon Pump in the Open Heart Surgeries. Medical Journal of School of Medicine, Harran University 2014 (11), 10-14 pp. 

D6. Aktürk Y, Dilek Yesilbursa D, *Uçar H*, Yücel E, Özdabakoglu O, Eryılmaz S, Sensoy B, Serdar OA, Aydınlar A. The Effect of Diurnal Blood Pressure Change on Heart Rate Recovery After Cardiac Stress Testing in Hypertensive Patients Receiving Treatment. Uludağ University, School of Medicine Journal 2008 (34), 9-13 pp. 

D7. Yesilbursa D, Aydinlar A, Karaagaç K, *Uçar H*, Aktürk Y, Yetgin ZA. Comparison of Depression and Anxiety Levels in Patients With Acute Coronary Syndrome. Journal of Clinical and Analytical Medicine 2014; DOI: 10.4328/JCAM.1443 

D8. Emül A, Karaagaç K, Yetgin ZA, *Uçar H*, Baran I, Aydınlar A. The Effects of Metabolic Syndrome on Aortic Distensibility in Patients with Angiographically Normal Coronary Arteries. Sakarya Medical Journal 2013; DOI: 10.5505/sakaryamj.2013.69672 

D9. Assessment of side branch patency using a jailed semi-inflated balloon technique with coronary bifurcation lesions. Ermiş E, *Uçar H*, Demirelli S, İpek E, Gür M, Çaylı M. Archive of Turkish Society of Cardiology 2018 Jul;46(5):340-348. doi: 10.5543/tkda.2018.47347.