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Dr. Ercan Karacaoglu is a specialist in Aesthetic, Plastic, and Reconstructive Surgery with over 20 years of experience. He has been a leading surgeon at Memorial Ataşehir Hospital since 2010. He also served as an Associate Professor at Brown University in the USA, where he received advanced training in surgical techniques.

Dr. Karacaoglu is recognized worldwide. He is a member of the American Society of Plastic Surgeons (ASPS), the European Board of Plastic, Reconstructive and Aesthetic Surgery (EBOPRAS), and the International Society of Aesthetic Plastic Surgery (ISAPS). He has written five international book chapters and published 31 international and 13 national research papers. He has also delivered 73 conference presentations and received 185 citations.

Dr. Karacaoglu specializes in advanced and minimally invasive procedures, such as endoscopic facial rejuvenation and laser lipolysis. He is an international speaker and educator, known for achieving natural and patient-focused results.

Prof. Dr. Burak Onan is a cardiovascular surgeon with expertise in mitral valve diseases, coronary artery bypass surgery, heart valve repair, and aortic aneurysm treatment. He has published 150 scientific articles. He has also presented his work at many national and international conferences.

Dr. Onan has held key positions in leading hospitals and academic boards. He also serves on ethics committees. He is a member of respected organizations, including the Turkish Society of Thoracic and Cardiovascular Surgery and the EACTS Robotic Cardiac Surgery Group. His work shows a strong commitment to innovation and high standards in cardiac care.

Dr. Ilker Comez is a specialist in Urology with a focus on High-Intensity Focused Ultrasound (HIFU) for prostate cancer treatment and laparoscopic simple prostatectomy (LSP). He is known for his proficiency in various surgical techniques, including the transvesical and retropubic transcapsular (Millin) technique, and both extraperitoneal and transperitoneal approaches for LSP. Dr. Comez has made substantial contributions to the literature on LSP, exploring its benefits, conflicts, and surgical techniques. His professional practice is marked by a commitment to improving lower urinary tract symptoms (LUTS) and reducing residual volume, while also minimizing cost and complications for patients.

Education Info:

 

Graduated from Orgeneral Halil Sözer Primary School, Eskisehir – 2003
Graduated from Kılıçoğlu Anatolian Highschool, Eskisehir -2007

Graduated from Marmara University School of Medicine with instructions fully in English, Istanbul, 2013

Internship in Abroad:

April, 2013  One month internship in a department of ENT in Basel University Hospital, Basel, Switzerland

Experience :

Work experience on Sleeping Apnea at the Labaratory of Polisomnography, Section of Pulmonary Diseases in Akademik Hospital, Istanbul. (2010-2011)

Work experience in Dr.Back Up Company related to Medline, Istanbul. ( between July-October of 2013)

Work experience in a clinic of emergency in Cankırı City Hospital, Cankırı. (from November of 2013 to January of 2014)

Work experience in a clinic of Otorhinolaryngology, Head and Neck Surgery in Istanbul Bagcilar Research Hospital(from July 2014-2018)

Work experience in a clinic of Otorhinolaryngology, Head and Neck Surgery in Istanbul Bahcelievler State Hospital(from September 2018-2020)

Work experience in a clinic of Otorhinolaryngology, Head and Neck Surgery in Istanbul Florya Medical Park Hospital ( from January 2021- November 2023)

Work experience as an instructor in medical school of Istanbul Aydın University ( from April 2021- December 2023)

Now working in his private clinic in Tesvikiye Mah. Terrace Fulya Center, Istanbul. 

Mostly Work On;

Septorhinoplasty,

Rhinoplasty,

Tipplasty,

Revision Rhinoplasty,

Ethnic Rhinoplasty

Asian Rhinoplasty

Otoplasty.

Liplift surgery,

Bichectomy,

Chin implants,

Septoplasty,

Endoscopic Septoplasty,

Congress:

2008, 2009, 2010 Masco (Marmara Medical Student Congress)

18th April 2013, International Congre for Pediatric Surgery, Aarau, Baden, Switzerland

37th Turkish National Congress of Otorhinolaryngology Head and Neck Surgery-2015

12th Turkish National Congress of  Rhinology-2016

8th Turkish National Congress of Istanbul’s Otorhinolaryngology Head and Neck Surgeons-2016

13th Turkish National Congress of  Rhinology-2017

14th Turkish National Congress of  Rhinology-2018

41th Turkish National Congress of Otorhinolaryngology Head and Neck Surgery-2020

International Reviews and Researchs:

http://mmj.dergisi.org/pdf/pdf_MMJ_523.pdf Pg.33,oral presentation 28.

“Comparison of Frey Syndrome Rates Following Superficial Parotidectomy and Partial Superficial Parotidectomy for Pleomorphic Adenoma.”

PMID:27391515

J Craniofac Surg. 2016 Jul;27(5):e469-71

“Can serum neutrophil to lymphocyte ratio be a predictive biomarker to help differentiate active chronic otitis media from inactive chronic otitis media?"

J Craniofac Surg. 

“Histopathological Effects of Bone Cement on Cartilage Tissue”

J Craniofac Surg. May/Jun 2019;30(3):936-939.

 doi: 10.1097/SCS.0000000000005202.

“Single-sided Sinonasal Mass: A Retrospective Study”

North Clin Istanb. 2018 Apr 12;5(2):139-143.

 doi: 10.14744/nci.2017.57984. eCollection 2018.

“Effects of Repeated Atmospheric Pressure Alterations on the Inner Ear.”

Aerosp Med Hum Perform. 2021 Jul 1;92(7):550-555.

doi:10.3357/AMHP.5732.2021. PMID: 34503628

“Association of Conductive Hearing Loss with the Structural Changes in the

Organ of Corti. “

ORL J Otorhinolaryngol Relat Spec. 2021;83(4):272-279. doi:

10.1159/000513871. Epub 2021 Mar 30. PMID: 33784680

“Chest Image Staging and Prevalence of Current Smoking among Hospitalized

COVID-19 Patients in Turkey.”

ENT-Uptades. 2022; 12: 44-50

DOI: 10.5152/entupdates.2021.21065

National Reviews and Researchs:

http://mmj.dergisi.org/pdf/pdf_MMJ_523.pdf Pg.33,oral presentation 28.

“The Reliability of Istanbul Municipal Water Supply in terms of public health”

Ongoing Researchs:

Serum Vitamin D düzeyinin BPPV üzerine etkisi.

Attended Medical Courses:

Rhinoplasty School in Eskisehir- July, 2015

Pediatric Airway Problems and live surgery- April, 2015

Functional Endoscopic Sinus Surgery- October, 2015

Functional Endoscopic Sinus Surgery Cadaver Course- August, 2016

Obstructive Sleep Apnea Course-October, 2016

Facial Plastic Course- October, 2016

Facial Plastic Course, Sapanca, 2017

Middle Ear Surgery Cadaver Course-  2017

Rhinoplasty School- 2019

All in One Rhinoplasty Course- 2019

All in One Rhinoplasty Course- 2020

Botox and Filler Course-2020

Foreign Languages:

English (Advanced)

German (Beginner)

Members of Communities:

Turk Tabipler Birligi- Turkish Doctor’s Union

EAACI- European Academy of Allergy and Clinical Immunology

2022 – Present

Private Clinic, Istanbul, Türkiye
Founder & Specialist in Obstetrics and Gynecology

Providing personalized care in all areas of gynecology, obstetrics, infertility, and in vitro fertilization (IVF)

Focus areas include: high-risk pregnancies, miscarriage management, gynecological surgery, genital aesthetics, and assisted reproductive techniques

Conducting patient-centered treatments and minor surgical procedures in a private practice setting.

2017 – 2022

Medipol University Hospital, Istanbul, Türkiye
Faculty Member & Specialist in Obstetrics and Gynecology

Instructor in gynecology and obstetrics internship programs for Faculty of Medicine students

Active in academic teaching, clinical training, and mentorship

Conducted scientific research with national and international publications

Specialized in advanced infertility treatment and reproductive endocrinology.

2018

Memorial Şişli Hospital, Istanbul, Türkiye
Gynecology, Obstetrics, and IVF Department

Worked in the IVF and infertility unit

Participated in advanced reproductive technologies and assisted conception treatments.

2009 – 2012

Adana Maternity Hospital, Adana, Türkiye
Specialist in Obstetrics and Gynecology (Compulsory Service)

Managed a high volume of deliveries and surgical cases

Gained extensive hands-on experience in routine and high-risk obstetric cases

Performed gynecological surgeries and emergency interventions.

2004 – 2009

Adana Numune Training and Research Hospital, Adana, Türkiye
Resident Physician, Obstetrics and Gynecology Department

Completed residency with a high case load in one of Turkey's busiest surgical training hospitals

Performed thousands of obstetric deliveries and gynecological surgeries

Ranked among the top 10 in the TUS national specialization exam in the gynecology/obstetrics category.

Certifications & Training

Ministry of Health Certification in Assisted Reproductive Techniques – Clinical and Laboratory Applications

Advanced training in infertility treatment, genital aesthetics, high-risk pregnancies, and minimally invasive gynecological procedures

2018 - Present, Istanbul/Istanbul/Türkiye

MEMORIAL BAHCELIEVLER HOSPITAL

Nuclear Medicine Specialist

2011 - Present, Antalya/Antalya/Türkiye

MEDSTAR HOSPITAL

Nuclear Medicine Specialist

1998 - 2011, Antalya/Antalya/Türkiye

AKDENİZ UNIVERSITY FACULTY OF MEDICINE

Lecturer at the Department of Nuclear Medicine

1997 - 1997, Izmir/Izmir/Türkiye

ATATURK EDUCATION AND RESEARCH HOSPITAL

Radiology Specialist

1992 - 1993, Ankara/Ankara/Türkiye

ANKARA ONCOLOGY HOSPITAL

Nuclear Medicine Specialist

2018 - Present, Istanbul/Istanbul/Türkiye

MEMORIAL BAHCELIEVLER HOSPITAL

Orthopedics and Traumatology Specialist

2016 - 2018, Istanbul/Istanbul/Türkiye

GOP TAKSIM TRAINING AND RESEARCH HOSPITAL

Orthopedics and Traumatology Education and Administrative Officer

2013 - 2016, Istanbul/Istanbul/Türkiye

GOP TAKSIM TRAINING AND RESEARCH HOSPITAL

Orthopedics and Traumatology Education Officer

2002 - 2013, Istanbul/Istanbul/Türkiye

TAKSIM TRAINING AND RESEARCH HOSPITAL

Orthopedics and Traumatology Specialist

2000 - 2002, Istanbul/Istanbul/Türkiye

BALTALIMANI TRAINING AND RESEARCH HOSPITAL

Orthopedics and Traumatology Specialist

1999 - 2000, Istanbul/Istanbul/Türkiye

TAKSIM TRAINING AND RESEARCH HOSPITAL

Orthopedics and Traumatology Specialist

1997 - 1999, Istanbul/Istanbul/Türkiye

PRIVATE AKSARAY VATAN HOSPITAL

Orthopedics and Traumatology Specialist

1994 - 1997, Kastamonu/Kastamonu/Türkiye

INEBOLU STATE HOSPITAL

Orthopedics and Traumatology Specialist – Compulsory Service

2021 - Present, Istanbul/Türkiye

MEMORIAL BAHCELIEVLER HOSPITAL

INTERNAL DISEASES AND GASTROENTROLOGY SPECIALIST

2014 - 2021, Gaziantep/Türkiye

GAZİANTEP UNIVERSITY FACULTY OF MEDICINE INTERNAL DISEASES DEPARTMENT/GASTROENTEROLOGY DEPARTMENT LECTURER

2012 - 2014, Gaziantep/Türkiye

GAZİANTEP ŞEHİT KAMİL STATE HOSPITAL GASTROENTEROLOGY DEPARTMENT (COMPULSORY SERVICE)

2018 - Present, Istanbul/Istanbul/Türkiye

MEMORIAL BAHCELIEVLER HOSPITAL

General Surgery Specialist

2016 - 2017, Istanbul/Istanbul/Türkiye

FLORANCE NIGHTINGALE KADIKOY AND ATAŞEHİR HOSPITALS

Director of the Surgery Center for Esophageal and Gastric Diseases

2015 - 2016, Istanbul/Istanbul/Türkiye

FLORANCE NIGHTINGALE KADIKOY HOSPITAL

Director of Colon and Rectum Surgery and Gastrointestinal System Motility Unit

2012 - 2016, Istanbul/Istanbul/Türkiye

TC ISTANBUL SCIENCE UNIVERSITY GENERAL SURGERY DEPARTMENT

Faculty Member, Advanced Laparoscopic Surgery

2011 - 2012, Istanbul/Istanbul/Türkiye

MINISTRY OF HEALTH HAYDARPASA NUMBER EA HOSPITAL

Chief of General Surgery Clinic

2008 - 2011, Istanbul/Istanbul/Türkiye

MINISTRY OF HEALTH HAYDARPASA NUMBER EA HOSPITAL

Deputy Chief of General Surgery Clinic

2005 - 2008, Istanbul/Istanbul/Türkiye

MINISTRY OF HEALTH HAYDARPASA NUMBER EA HOSPITAL

Chief Assistant of General Surgery Clinic

2003 - 2005, Istanbul/Istanbul/Türkiye

MINISTRY OF HEALTH SISLI ETFAL EA HOSPITAL

Chief Assistant of General Surgery Clinic

1997 - 2002, Istanbul/Istanbul/Türkiye

TC ISTANBUL UNIVERSITY CERRAHPAŞA MEDICAL FACULTY

Clinical Chief Assistant of the Department of General Surgery

⸻

EDUCATION

2022

Associate Professor

2017 - 2020, Istanbul/Turkey

University of London, School of Hygiene and Tropical Medicine

Master’s Program in Clinical Trials

2013, Istanbul/Turkey

AMERICAN HOSPITAL, IVF UNIT

Ministry of Health Subspecialty Training in Reproductive Medicine

2005 - 2010, Istanbul/Turkey

İSTANBUL GÖZTEPE TRAINING AND RESEARCH HOSPITAL

Residency in Obstetrics and Gynecology

1998 - 2004, Istanbul/Turkey

İSTANBUL UNIVERSITY, CERRAHPAŞA FACULTY OF MEDICINE

Medical Doctor (M.D.) Education                                                                      

dr.Semih Tiber Menetşe

Education

2009-2014 Marmara University Faculty of Medicine

2016-2023 Okmeydanı Training and Research Hospital (Specialty)

Experience

2010 Cardiology Clinic, Cardiology Hospital C. I . Parhon Iaşi/ Romania

2011 Gastroenterology Clinic, Hospital Clínico Universitario Lozano Blesa Zaragoza/ Spain

2012 Plastic Surgery Clinic Sapienza University of Rome Italy

2012 Herlev Hospital, Copenhagen Denmark

2012 Hippokration General Hospital, Athens Greece

2016-2023 Okmeydani Training and Research Hospital

2023-2024 Necip Fazil Training and Research Hospital (Chief Physician)​

Dr. Senay Yilmaz is an experienced Eye Diseases Specialist. She has performed over 9,000 surgeries, including advanced procedures like strabismus surgery. Dr. Yilmaz is a member of the Turkish Society of Ophthalmology (TOD).

She has published three scientific articles and has presented her research at national and international congresses, including the European Strabismological Association. Her work highlights her expertise and dedication to ophthalmology.

Dr. Serkan Orhan is an experienced otolaryngologist and facial plastic surgeon. He has 25 years of practice, focusing on rhinoplasty and advanced ENT procedures. Dr. Orhan has performed over 5,500 treatments. His expertise includes cochlear implant placement, septoplasty, nasal polyp surgery, embolization for epistaxis, and prosthetic ear and nose surgeries.

Dr. Orhan is a faculty member at the University of Istanbul. He completed his residency at the ORL Department of Radboud University in the Netherlands. He also attended advanced courses at the Royal National Ear Nose and Throat Hospital in London. His international training highlights his dedication to his field.

Education Information
2012-2017 Mental Health Psychiatry Residency at Istanbul University Cerrahpaşa Faculty of Medicine
Course and Seminar Participations :
Cognitive Behavioral Therapy by Prof. Dr. Mehmet Zihni Sungur
Various trainings and presentations at National and International Congresses
Personal Competencies:
Foreign Language: English, Russian

Medical Interests and Activities 

Cardiac Rhythm Disorders 

Pacemaker Implantations 

Electrophsiology and Catheter Ablation 

Atrial Fibrilation Atration 

Resynchronisation Therapy (Pacemaker) for Heart Failure 

Coronary Artery Interventional Therapies (Angiography, Balon – Stent Procedures)

Education and Experience 

Department of Cardiology, Liv Hospital, Ulus 

Department of Cardiology, Anadolu Health Center 

Department of Electrophysiology, University of Leipzig – Heart Center, Germany • Siyami Ersek Cardiovascular Surgery Center 

Faculty of Medicine, İstanbul University Memberships • Turkish Society of Cardiology 

European Society of Cardiology

Memberships 

Turkish Society of Cardiology 

European Society of Cardiology 

Researches and Publications 

International: 16 

National: 20

Book Chapters: 4

Cardiovascular Surgery (Pediatric ) 

Prof. Dr. Emin Tireli completed his Medical initiative degree from Istanbul University Faculty of Medicine Cardiovascular Surgery. He also did his Specialization in Cardiac Surgery from the same university.  As a professor, he provided his service to the university. Currently, he is working as a specialist at Altınbaş University Hospital Medical Park Bahçelievler in the department of Cardiac Surgery.

 Prof. Dr. Emin Tireli is proficiently treating such problems

• Congenital heart disease ,
• Pediatric cardiac surgery
• Adult cardiac surgery 
• Aortic surgery 
• Aneurysm 
• Coronary artery 
• Heart valve surgery 

Scientific Publications

1. [The effect of two different glycemic management protocols on postoperative cognitive dysfunction in coronary artery bypass surgery].

Kurnaz P, Sungur Z, Camci E, Sivrikoz N, Orhun G, Senturk M, Sayin O, Tireli E, Gurvit H.

Rev Bras Anestesiol. 2017 May - Jun;67(3):258-265. doi: 10.1016/j.bjan.2016.01.007. Epub 2017 Feb 27. Portuguese.

PMID: 28256333 Free Article

Select item 25134394

2. The role of Porphyromonas gingivalis in the development of atherosclerosis and its relationship with fim A genotype.

Ziver T, Balci A, Ergin S, Gode S, Kuskucum M, Torlak Z, Yuksel P, Tokman HB, Ipek G, Tireli E, Midilli K, Yekeler I, Kiraz N, Kocazeybek B.

Clin Lab. 2014;60(7):1225-32.

PMID: 25134394

Select item 24631983

3. Pressure-controlled mechanical ventilation is more advantageous in the follow-up of patients with chronic obstructive pulmonary disease after open heart surgery.

Ugurlucan M, Basaran M, Erdim F, Selimoglu O, Caglar IM, Zencirci E, Filizcan U, Ogus NT, Yildiz Y, Tireli E, Isik O, Dayioglu E.HeartSurg Forum. 2014 Feb;17(1):E1-6. doi: 10.1532/HSF98.2013236

PMID: 24631983

Select item 23571798

4. Extracardiac off-pump fontan completion for single ventricle with dextrocardia. Goksel OS, Gok E, Tireli E, Dayioglu E.Innovations (Phila). 2013 Jan-Feb;8(1):73-5. doi: 10.1097/IMI.0b013e3182810e08.

PMID: 23571798

Select item 22450102

5. Aorto-GoreTex central shunt with side-to-side aortic anastomosis.Uğurlucan M, Tireli E.Ann Thorac Surg. 2012 Apr;93(4):1400-1; author reply 1401. doi: 10.1016/j.athoracsur.2011.10.049. No abstract available. PMID: 22450102

Select item 22362623

6. Transcaval invasion of right atrium by thymoma: resection via transient cava-pulmonary shunt. Toker A, Tireli E, Tanju S, Kaya S.Eur J Cardiothorac Surg. 2012 May;41(5):1175-7. doi: 10.1093/ejcts/ezr261. Epub 2012 Feb 22.PMID: 22362623 Select item 22124632

7. Aorta after stent grafting for mycotic aneurysm.Alpagut U, Ugurlucan M, Tireli E, Rozanes I, Dayioglu E.Arq Bras Cardiol. 2011 Oct;97(4):e78-81. English, Portuguese, Spanish.

PMID: 22124632 Free Article Select item 21729497

8. Modified Nikaidoh procedure in a patient with transposition of the great arteries, ventricular septal defect, and left ventricular outflow tract obstruction with unusual coronary anatomy. Ugurlucan M, Sayin OA, Tireli E Cardiol Young. 2011 Dec;21(6):703-6. doi: 10.1017/S104795111100062X. Epub 2011 Jun 27. PMID: 21729497 Select item 21440183,

9. Off-pump Fontan and fenestration during single ventricle palliation. Ugurlucan M, Karabay BC, Tireli E.Ann Thorac Surg. 2011 Apr;91(4):1309-10. doi: 10.1016/j.athoracsur.2010.07.101. No abstract available. PMID: 21440183 Select item 21177304

10. Endovascular treatment of mycotic saccular aneurysms of the thoracic aorta. Ugurlucan M, Umaroglu S, Tireli E, Alpagut U.Interact Cardiovasc Thorac Surg. 2011 Jan;12(1):63. doi: 10.1510/icvts.2010.249102A. No abstract available.PMID: 21177304 Select item 21158914

11. Bilateral PDA in a patient with VSD and pulmonary atresia. Ugurlucan M, Sayin OA, Dayioglu E, Tireli E. JCard Surg. 2011 Jan;26(1):107-10. doi: 10.1111/j.1540-8191.2010.01165.x. Epub 2010 Dec 16.PMID: 2115891 Select item 20954441

12. Aneurysm and Helicobacter pylori relationship: the seropositivity of CagA, VacA and other antigens of Helicobacter pylori in abdominal and ascending aortic aneurysms.

Ziver T, Yuksel P, Ipek G, Yekeler I, Bayramoglu Z, Tireli E, Saribas S, Aslan M, Yalvac SD, Ozdomanic I, Torlak Z, Dirican A, Torun MM, Kocazeybek B.

New Microbiol. 2010 Jul;33(3):233-42.

PMID: 20954441 Free Article Select item 20951266

13. Surgical versus endovascular treatment for type B aortic dissections.

Ugurlucan M, Karabay BC, Alpagut U, Tireli E. J Thorac Cardiovasc Surg. 2010 Nov;140(5):1202-3.e1. doi: 10.1016/j.jtcvs.2010.06.062. No abstract available. PMID: 20951266 Free Article Select item 20942745

14. Glutamine enhances the heat shock protein 70 expression as a cardioprotective mechanism in left heart tissues in the presence of diabetes mellitus.Ugurlucan M, Erer D, Karatepe O, Ziyade S, Haholu A, Gungor Ugurlucan F, Filizcan U, Tireli E, Dayioglu E, Alpagut U.  Expert Opin Ther Targets. 2010 Nov;14(11):1143-56. doi: 10.1517/14728222.220100.521500.

PMID: 20942745

Select item 20694768

15. Infrarenal aortic coarctation. Alpagut U, Ugurlucan M, Sayin OA, Tireli E, Dayioglu E.Wien Med Wochenschr. 2010 Jul;160(13-14):372-5. doi: 10.1007/s10354-010-0810-5. PMID: 20694768

Select item 20519309

16. The aortoplasy technique. Karabay CB, Ugurlucan M, Abbasi SH, Tireli E.Asian Cardiovasc Thorac Ann. 2010 Jun;18(3):316. doi: 10.1177/0218492310365362. No abstract available. PMID: 20519309

Select item 20335395

17. eComment: Advance of guidewire from the brachial artery to facilitate correct positioning of the stent graft during repair of type 3 aortic dissections. Ugurlucan M, Alpagut U, Tireli E, Dayioglu E .Interact Cardiovasc Thorac Surg. 2010 Apr;10(4):599. doi: 10.1510/icvts.2009.223040A. No abstract available. PMID: 20335395 Select item 20042418

18. Single-institutional 22 years experience on cardiac myxomas. Cetin G, Gursoy M, Ugurlucan M, Uzunhasan I, Hatemi AC, Tireli E, Kucukoglu S, Kansiz E. angiology 2010 Jul;61(5):504-9. doi: 10.1177/0003319709352489. Epub 2009 Dec 29. PMID: 20042418

Select item 19766858

19. Minimally invasive mitral valve surgery after previous sternotomy. Goksel OS, Tireli E. Ann Thorac Surg. 2009 Oct;88(4):1384; author reply 1384. doi: 10.1016/j.athoracsur.2009.03.020. No abstract available. PMID: 19766858 Select item 19660147

20. Single-stage correction, with extensive pulmonary arterial reconstruction, of a pulmonary arterial sling associated with tetralogy of Fallot. Goksel OS, Tireli E, Celebi A. Cardiol Young. 2009 Sep;19(5):519-21. doi: 10.1017/S1047951109991119. Epub 2009 Aug 7. PMID: 19660147