Doctor with over 20 years of experience in physical medicine and rehabilitation, including leading the Rehabilitation Department and Deputy Chief of the Rehabilitation Department. Has a Specialist Certification in Algiatry and Physical Medicine and Rehabilitation, and has completed courses in myoskeletal medicine, medical acupuncture and physical therapy of the pelvic floor. Has published several works in the field of rehabilitation.
Dr. Manuela Seifert is a top German breast specialist.
Dr. Manuela Seifert is a specialist in diagnostics, therapy and aftercare of breast diseases and sonography.
Dr. Seifer applies breast conserving operations as a key treatment method.
Dr. Séverine Iborra is the Chief Physician of the Department of Gynecology and Obstetrics at Städtisches Klinikum Solingen. Her responsibilities include obstetrics, the delivery room, the neonatal unit, and gynecology. The department also includes the Senology/Breast Clinic at the Bergisches Breast Center Solingen, led by Dr. Manuela Seifert.
Dr. Séverine Iborra is originally from France. She began her medical studies at the University of Lyon and later transferred to Albert-Ludwigs University in Freiburg, where she received her medical license in 2007. She earned her doctorate in 2008 for experimental research in molecular oncology. From August 2008 to November 2013, Dr. Iborra worked as a resident at the University Women’s Clinic in Freiburg. After passing her specialist exams in gynecology and obstetrics, she continued her career as a specialist at the same clinic. In November 2015, she moved to RWTH University Hospital Aachen as a senior physician.
At the Clinic for Gynecology and Obstetrics, under the leadership of Prof. Dr. E. Stickeler, Dr. Iborra led the obstetrics department from 2017 to 2019. Since December 2017, she was responsible for organizing education in the department, and in October 2019, she became the Managing Senior Physician and Personnel Senior Physician of the clinic, a position she held until she moved to Solingen.
In addition to her scientific work, with numerous publications and presentations at major gynecological conferences, Dr. Iborra deepened her medical specialties. She obtained certifications in oncological diagnostics and therapy from the Gynecological Oncology Working Group, as well as additional qualifications in Cervical Pathology and Colposcopy (AGCPC), Urogynecology and Pelvic Reconstructive Surgery (AGUP), and the Professional Association of Gynecologists (BVF).
In 2019, Dr. Iborra successfully completed further specialization in “Gynecological Oncology” and “Special Obstetrics and Perinatal Medicine.” She is an active member of leading German medical societies in her field, including the German Society for Gynecology and Obstetrics, the Cervical Pathology and Colposcopy Working Group, and the German Society for Prenatal and Birth Medicine.
Treatments Offered in Our Gynecology Department
Whenever possible, we offer all procedures as minimally invasive treatments using laparoscopy or the Da Vinci robotic system.
Experience
2019 - 2022
University of Health Sciences, Faculty of Medicine, Ankara City Hospital, Cardiology Clinic, Ankara
2017 - 2019
University of Health Sciences, Faculty of Medicine, Turkey Higher Specialization Training and Research Hospital, Cardiology Clinic, Ankara,
2012 - 2017
Türkiye Higher Specialization Training and Research Hospital, Cardiology Clinic, Ankara,
2012 - 2017
T.R. Karabük University, Faculty of Medicine, Department of Cardiology
2006 - 2006
Türkiye Higher Specialization Training and Research Hospital, Cardiology Clinic, Ankara,
2001 - 2006
Türkiye Higher Specialization Training and Research Hospital, Cardiology Clinic, Ankara,
1996 - 2001
Türkiye Higher Specialization Training and Research Hospital, Cardiology Clinic, Ankara,
Education
2017 Karabük University, Faculty of Medicine, Department of Cardiology
2006 Türkiye Higher Specialization Training and Research Hospital, Cardiology Clinic
2001 Türkiye Higher Specialization Training and Research Hospital, Ankara, Cardiology
1996 Ankara University, Faculty of Medicine
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PROFESSIONAL EXPERIENCE
2011-2012
Erzurum Koprukoyu State Hospital
Department: General Medicine
2012-2017
Istanbul University Cerrahpaşa Medical Faculty
Department: Internal Medicine
06/2017-10/2017
Istanbul Gaziosmanpasa Taksim Training and Research Hospital
Department: Internal Medicine
10/2017-11/2018
Istanbul University Istanbul Medical Faculty
Department: Allergy and Immunology Fellowship
2018/2022
Istanbul University Oncology Institute
Department: Medical Oncology Fellowship
2022-2023
Tekirdag City Hospital
Department: Medical Oncology Specialist
2023-present
Istanbul Medipol University Medipol Bahcelievler Private Hospital
Department: Medical Oncology Assoc. Prof.
EDUCATION
2005-2011
Medical Education
Sivas Cumhuriyet University Medical Faculty, Sivas, Turkey
2012-2017
Internal Medicine
Istanbul University Cerrahpaşa Medical Faculty, Department of Internal Medicine, Istanbul, Turkey
2017-2018
Allergy-Immunology Fellowship
Istanbul University Istanbul Medical Faculty
Department of Internal Medicine, Division of Allergy and Immunology, Istanbul, Turkey
2018-2022
Medical Oncology Fellowship
Istanbul University Oncology Institute, Department of Medical Oncology, Istanbul, Turkey
2022
ESMO Board Certification in Medical Oncology
10th September 2022 in Paris, France.
2023
Medical Oncology Assoc. Prof.
Istanbul Medipol University Department of Medical Oncology, Istanbul, Turkey
INTERNATIONAL CLINICAL TRIALS:
1. Astefania - ROCHE
2. PFİZER
3. RECITE - AMGEN
4. NAVIGATE - BAYER
5. RUBY - Tesaro (PRA)
6. ENGOT-ov43/GOG-3036 - MSD
7. ASTRA ZENECA
8. ROSY-O - ASTRA ZENECA
INTERNATIONAL PUBLICATIONS
I. Published journal articles indexed by SCI, SSCI, and AHCI
Weekly Paclitaxel in Classic Kaposi Sarcoma
Carboplatin Desensitization in Ovarian Carcinoma
High-Dose Chemotherapy for Ewing’s Sarcoma
Multidrug Refractory TFE3(+) Renal Cell Carcinoma
Crizotinib Efficacy in NSCLC with MET Alterations
Clinicopathological Features in ALK Mutant NSCLC
PSMA-Based Tumor Burden in Prostate Cancer
Atezolizumab in Metastatic Urothelial Carcinoma
Pulmonary Sarcomatoid Carcinoma
Prognostic Factors in Atezolizumab-Treated Urothelial Carcinoma
Atezolizumab with Chemotherapy in Small Cell Lung Cancer
FOLFIRINOX vs. Gemcitabine + Nab-Paclitaxel in Pancreatic Cancer
Trastuzumab Emtansine in Older HER2-Positive Breast Cancer Patients
Real-Life Efficacy of Osimertinib in Advanced NSCLC
ALK-Positive Cells Percentage and Alectinib Efficacy
Real-World Data on Alectinib in ALK-Positive NSCLC
Prognostic Factors in Metastatic RCC with T790M Mutation
FLOT Regimen in Metastatic Gastric Cancer
Desensitization Protocol in Lenalidomide Hypersensitivity Reactions
Factors Associated with Diagnostic Skin Test Positivity in PPI Hypersensitivity
Efficacy of Capecitabine and Temozolomide in Neuroendocrine Tumors
Subsequent Treatments in Hormone-Positive Breast Cancer Progression
Termination of Trastuzumab in HER2-Positive Metastatic Breast Cancer
Long-term Outcomes and Predictors of Recurrence in Node-Negative Early Stage Breast Cancer
Prognostic Factors Influencing PFS in HER2-Positive Metastatic Breast Cancer
Treatment Efficacy of Ribociclib or Palbociclib plus Letrozole in Metastatic Breast Cancer
Efficacy and Safety of Sorafenib in Adult Metastatic Osteosarcoma Patients
Single-Agent Temozolomide as Salvage Therapy in Heavily Pretreated Metastatic Sarcoma Patients
Outcomes and Prognostic Factors in Metastatic Renal Cell Carcinoma with Brain Metastases
FLOT Regimen in First-Line Treatment of Metastatic Gastric Cancer
Prognostic Factors of Perioperative FLOT Regimen in Operable Gastric Cancer
Efficacy and Outcomes of Systemic Chemotherapy in Posttransplant Kaposi Sarcoma
Comparison of Second-Line Treatments in Metastatic Renal Cell Carcinoma
Toxicity Management and Effectiveness of Regorafenib in Advance GIST Patients: A Real-world Study - Authors: Paksoy, N., Ferhatoğlu, F., Doğan, İ., Khanmammadov, N., Bozbey, H. U., Karabulut, S., & Taştekin, D. - Journal: TURKISH JOURNAL OF ONCOLOGY, 1(1)
Demographic and Clinical Features and Factors Associated with Survival in Patients with Primary Glomerulonephritis: Single Tertiary Center Experience - Authors: Paksoy, N., Trabulus, S., Seyahi, N., & Altiparmak, M. R. - Journal: Namik Kemal Tip Dergisi, 11(1)
Efficacy of Sorafenib in Symptomatic Patients with Pretreated Progressive Desmoid Tumors - Authors: Paksoy, N., Ferhatoglu, F., Dogan, I., Ak, N., Pehlivan, M., Ekenel, M., & Basaran, M.
Nodal Response to Neoadjuvant Chemotherapy is a Better Predictive Factor of Survival Than Miller-Payne Scoring in Breast Cancer - Authors: Ak, Naziye, et al. - Journal: Journal of Oncological Sciences, 7.2: 42-49
Evaluation of Prognostic and Predictive Values of Hemogram Parameters in Patients with Advanced Stage Ovarian Carcinoma - Authors: Ak, Naziye, et al. - Journal: Turkish Journal of Oncology/Türk Onkoloji Dergisi, 2021, 36.4
Identifying Risk Factors Associated with Survival and Drug-Related Toxicities in Imatinib-Resistant Gastrointestinal Stromal Tumor (GIST) Patients Treated with Sunitinib - Authors: Ferhatoglu, F., Karabulut, S., Paksoy, N., & Tastekin, D.
Real-life Outcomes of ROS1 Fusion-positive Metastatic Lung Cancer Patients who were Treated with Crizotinib - Authors: Dogan, İ., Khanmammadov, N., Paksoy, N., Ferhatoglu, F., Aydın, E., Vatansever, S., & Aydine, A. - Journal: TURK ONKOLOJI DERGISI-TURKISH JOURNAL OF ONCOLOGY
Predictors of the acquisition of T790M mutation in EGFR-mutant metastatic lung cancer patients who were treated with EGFR inhibitors - Authors: Dogan, I., Khanmammadov, N., Paksoy, N., Vatansever, S., Saip, P., & Aydıner, A. - Journal: Eurasian Journal of Pulmonology
Laterality of Adrenal Gland Metastasis in Lung Cancer: Results of a Comparative Study - Authors: Ferhatoglu, F., Gagatay, T., Okumus, G., Aydiner, A., Paksoy, N., Ak, N., ... & Saip, P. - Journal: Eurasian Journal of Medical Investigation, 7(2)
Poor Risk Factors Affecting Cancer Patients Infected with Covid-19: A Retrospective Comparative Study from a Pandemic Hospital - Authors: Ferhatoglu, F., Kapağan, T., Paksoy, N., Ak, N., Medetalibeyoğlu, A., Şenkal, N., ... & Vatansever, S. - Journal: Turk Onkoloji Dergisi, 38(1)
Systemic Treatment Outcomes of Progressive Medullary Thyroid Carcinoma from the Registries of a Tertiary Cancer Center - Authors: Ferhatoglu, F., Paksoy, N., & Başaran, M. - Journal: Namik Kemal Tip Dergisi, 10(4)
Evaluation of clinical features and risk factors related to late recurrence (> 5 years) in patients with breast cancer - Authors: Ferhatoglu, F., Aydiner, A., & Paksoy, N. - Journal: Journal of Surgery & Medicine (JOSAM), 6(12)
Assessing the Clinical Impact of Lutetium-177 DOTATATE Peptide Receptor Radionuclide Therapy (PRRT) on Metastatic Neuroendocrine Tumors: A Multicenter Real-World Data from Türkiye
Thesis:
Istanbul University Cerrahpaşa Medical Faculty, Internal Medicine Department PAKSOY, Nail. Demographical, clinical characteristics and survival factors in patients withprimary glomerulonephritis: Cerrahpasa Medical Faculty Experience. (2016)
International Refereed Congress / Symposium Publications in Proceedings (ASCO/ESMO Abstracts)
Prognostic factors influencing progression-free survival in HER2 positive metastatic breast cancer patients who treated with lapatinib and capecitabine combination
Efficacy of regorafenib and 5-fluorouracil-based rechallenge treatment in the third-line treatment of metastatic colorectal cancer: A Turkish oncology group study
Long-term outcomes and predictors of recurrence in patients with early-stage node-negative breast cancer
Efficacy of temozolomide in pretreated patients with metastatic sarcoma
Efficacy of sorafenib in symptomatic patients with pretreated progressive desmoid tumors
Efficacy of sorafenib in heavily pretreated adult patients with metastatic osteosarcoma
Outcomes and prognostic factors in metastatic renal cell carcinoma patients with brain metastases
Association of response to first-line chemotherapy with the efficacy of atezolizumab in patients with metastatic urothelial carcinoma
Safety and survival in adult women with platinum-sensitive relapsed BRCA mutant ovarian cancer: A study of patients in Olaparib Turkey Early Access Program—LynTurk study
Atezolizumab in patients with metastatic urothelial carcinoma who have progressed after first-line chemotherapy: Results of real-life experiences
Experience
2016 - 2022
ISTANBUL MEDIPOL UNIVERSITY
2010 - 2016
BEZM-I ÂLEM FOUNDATION UNIVERSITY
2010 - 2015
Bezmialem Vakif University Faculty of Medicine
2009 - 2010
Bagcilar Training and Research Hospital
2009 - 2010
ISTANBUL BAGCILAR TRAINING AND RESEARCH HOSPITAL
1997 - 2009
ISTANBUL HASEKI TRAINING AND RESEARCH HOSPITAL
1997 - 2009
Haseki Training and Research Hospital
Education
2016
BEZM-I ÂLEM FOUNDATION UNIVERSITY, DEPARTMENT OF ANESTHESIOLOGY AND REANIMATION
1997
Istanbul Haseki Training and Research Hospital, Anesthesiology and Reanimation
1993
ISTANBUL HASEKI TRAINING AND RESEARCH HOSPITAL, Medical Specialization
1989
Istanbul University, Faculty of Medicine
1983
ISTANBUL UNIVERSITY, CERRAHPAŞA FACULTY OF MEDICINE, FACULTY OF MEDICINE
Experience
2018 - 2022
Health Sciences University – Şişli Hamidiye Etfal Training and Research Hospital
2016 - 2018
Diyarbakır Memorial Dicle Hospital Cardiology Clinic
2010 - 2010
Dicle University Faculty of Medicine, Department of Cardiology
2010 - 2016
Private Veni Vidi Hospital, Cardiology Clinic Supervisor
2006 - 2010
Dicle University Faculty of Medicine, Department of Cardiology
2005 - 2006
Urfa State Hospital
1999 - 2005
Turkey High Specialization Training and Research Hospital
1998 - 1999
Duruca Health Center
Education
2018
Health Sciences University, Cardiology
2010
Dicle University, Department of Cardiology
2005
Cardiology Turkey High Specialization Training and Research Hospital, Medical Specialization
1998
Ege University, Faculty of Medicine
Experience
2016 - 2019 Özel Gebze Konak Hastanesi
2014 - 2015 Özel Medicana Çamlıca Hastanesi
2013 - 2014 Özel Batman Hastanesi
2011 - 2013 Batman Bölge Devlet Hastanesi
Üsküdar Üniversitesi
Gazi Üniversitesi Tıp Fakültesi
Education
2011 Bezmialem Vakıf Üniversitesi Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon
2005 Marmara Üniversitesi, İngilizce Tıp Fakültesi
Education:
İstanbul Pertevniyal Anatolian High School
Trakya University Faculty of Medicine
İstanbul Okmeydanı Training And Research Hospital Family Practice
Experience:
Liv Hospital Ulus 2021-
Acıbadem Fulya Hospital
Adıyaman Sincik District State Hospital
Okmeydanı Training and Research Hospital
İstanbul Gaziosmanpaşa Karlıtepe A.H.D, Bağlarbaşı A.H.D. and Pazariçi A.H.D
Memberships:
Turkish Medical Association (Istanbul Chamber of Doctors)
TAHUD (Turkish Family Physicians Specialty Association)
The doctor is a member of several professional organizations including the Professional Association of German Internists, the German Society of Internal Medicine, the German Society of Pneumology and Respiratory Medicine, the German Sleep Society, the German Lung Foundation, the European Respiratory Society, the Society for Pulmonary Training, the North German Bronchial Carcinoma Working Group, and the North German Society for Pneumology.
Experienced Consultant Physiatrist currently working at Beroun Rehabilitation Hospital with previous experience as a Rehabilitation Doctor, Rehabilitation Medicine Consultant, Chief Physiotherapist, Medical Director and General Practitioner. Has highest Medical Doctor degree from Masaryk University, as well as board certifications in Rehabilitation and Physical Medicine, and General Surgery. Has experience lecturing and has authored numerous publications.