Best Medication therapy for urinary incontinence urologists: TOP 46 doctors

Dr. Ismael Avila Iniguez is a certified General Surgeon and Urologist who graduated from the Medical Faculty of the Autonomous University of Guadalajara with honors and has performed over 3,000 Urological and Oncological surgical procedures. He is a member of various associations and has been recognized for his work in organ transplant units and cancer care. He regularly attends seminars both in the US and Mexico.

Dr. graduated from Istanbul Faculty of Medicine in 2004. Tuncay TAŞ, after the training he received at Heildelberg University, Germany, Heilbronn SLK Hospital "Laparoscopy, Robotics and Oncology Center" in 2006 and 2007, has served his patients for many years, especially in the field of Robotic and Laparoscopic surgery in Turkey. Dr. TAŞ completed his urology specialization in Istanbul in 2010.

The majority of urology practice consists of cancer diagnosis, treatment and follow-up; prostate, kidney, bladder diseases; microscopic varicocele operation, MicroTESE, sperm enhancing treatments, azoospermia, erectile dysfunction treatments and other testicular diseases in the field of men's health; HOLEP, Rezum and TUR Prostate surgery in the field of adult male health; urinary incontinence treatments in the field of women's health; minimally invasive kidney stone treatments in general urology; Surgical treatment of hypospadias and other urological disorders in children.

He works as a faculty member at the Private Urology Clinic (Safe Urology) and the University.

Scientific Organizations of which he is a Member

Turkish Urology Association

Turkish Medical Association

Endourology Association

European Association of Urology

International Stem Cell Applications Association

Specializations

Urological Oncology

Laparoscopic Urology

kidney problems

Neurourology

Penis Surgery

Education

2004

Istanbul Faculty of Medicine

medical School

2006 2007

University of Heidelberg, Germany

Scholarship: Urological Oncology and Laparoscopic Urology Department of Urology SLK Kliniken Heilbronn University of Heidelberg, Germany

2010

Health Sciences University Taksim Training and Research Hospital

Postgraduate Medical Education – Specialization in Urology

I am Assoc. Prof. Dr. Esra Ozbasli, a board-certified OB-GYN and Genital Cosmetic Surgeon with over 21 years of experience. My dedication to excellence and patient satisfaction has established our clinic as a trusted destination for women’s health and aesthetic procedures in Nişantaşı, heart of Istanbul.I received my medical degree from Istanbul University Cerrahpaşa Medical Faculty, followed by specialized training in obstetrics and gynecology at Istanbul Zeynep Kamil Women and Children Diseases Training and Research Hospital. After working as an academician at Acıbadem University for 12 years, I became an associate professor there by exhibiting my scientific articles in many respected international scientific journals published in Pubmed. During this period, I trained many medical students and OBGYN specialist colleagues in the field of genital aesthetics surgery, urogyneacology. My advanced training in genital cosmetic surgery provided me with expertise in the latest techniques for enhancing and restoring female genital aesthetics and function. I hold certifications in Genital Aesthetics and Cosmetic Gynecology (Vaginal Rejuvenation), Certificate of da Vinci System Training as a Console Surgeon (since 2013) and the ECFMG certificate for foreign medical graduates. Additionally, I possess advanced-level English proficiency (TOEFL score 600 in 2003), ensuring clear communication with international patients. I have completed an observership in New York University in 2005. 

Specialized Services:

 • Genital Cosmetic Surgery: Labioplasty, hudoplasty, vaginoplasty, lipofilling, PRP therapy, hyaluronic acid filling, hymenoplasty, labia majora plasty, vulvar whitening, G-shot, O-shot, treatment of atrophic vagina, lichen sclerosis, and vaginal laxity.

 • Minimally Invasive Surgery: Laparoscopy, robotic surgery, hysteroscopy for fibroids, endometrioma, endometrial polyps, ovarian cysts, tubal ligation, intrauterine septum resection, abnormal vaginal bleeding, and hysterectomy.

 • Menopause Treatment: Bioidentical hormone therapy for managing menopausal symptoms, mezotherapy and laser for atrophic vagina.

•Urinary incontinence treatment: Sling operations (TOT), hyaluronic acid filling, laser treatments.

• Cervical Dysplasia Diagnosis and Treatment: Co-test, PAP-smear, colposcopy guided biopsy and LEEP conization.

International Patient Services: 

We offer a package service for our foreign patients that includes: 

• Arrangements for flights and hotel stays • Pick-up service from the airport and hotel • Assistance throughout your stay to ensure a smooth and stress-free experience • Sightseeing of Istanbul before the surgery if requested

Why Choose Us: 

• Expertise: With over two decades of specialized experience, I offer advanced surgical techniques and personalized care. 

• Innovation: Utilizing the latest technology in minimally invasive and cosmetic procedures to ensure optimal results.

 • Quality Care: I perform my surgeries in A-class hospitals equipped with advanced technological surgical devices. 

• Compassion: Committed to providing a comfortable, supportive, and private environment for all patients. 

Experience

2017 - 2022 Haseki Training and Research Hospital, Associate Professor

2017 - 2022 Haseki Training and Research Hospital

2013 - 2017 Haseki Training and Research Hospital

2013 - 2017 Haseki Training and Research Hospital, Chief Resident

2010 - 2013 Silivri State Hospital (Compulsory Service Obligation)

2008 - 2008 University of Michigan Medical School

2005 - 2010 Istanbul Medical Faculty, Department of Urology

Education

2010 Istanbul University, Istanbul Medical Faculty, Department of Urology

2004 Istanbul University, Istanbul Medical Faculty

Publications

International Peer-Reviewed Journals:

Culpan M, Atis G, Sanli O, Bozkurt Y, Atmaca AF, Semerci B, Kutsal C, Canda AE, Akbulut F, Tugcu V, Boylu U, Erturhan S, Koca O, Ateş F, Halis F, Soyupek S, Turna B, Cakmak S, Sahin S, Erdem S, Yildirim A. "Comparison of Tumor Enucleation and Standard Partial Nephrectomy According to Trifecta Outcomes: A Multicenter Study by the Turkish Academy of Urology, Uro-Oncology Working Group." J Invest Surg. 2022 May;35(5):1112-1118.

Sahan M, Sarilar O, Akbulut MF, Demir E, Savun M, Sen O, Ozgor F. "Flexible ureterorenoscopy and laser lithotripsy with regional anesthesia vs general anesthesia: A prospective randomized study." Int Braz J Urol. 2020 Nov-Dec;46(6):1010-1018.

Cubuk A, Yanaral F, Savun M, Ayranci A, Erbin A, Yazici O, Akbulut MF, Sarilar O. "Modified autologous transobturator tape surgery - evaluation of short-term results." Ginekol Pol. 2020;91(2):51-56.

Kandemir E, Savun M, Sezer A, Erbin A, Akbulut MF, Sarilar Ö. "Comparison of Miniaturized Percutaneous Nephrolithotomy and Standard Percutaneous Nephrolithotomy in Secondary Patients: A Randomized Prospective Study." J Endourol. 2020 Jan;34(1):26-32.

Ucpinar B, Erbin A, Ayranci A, Caglar U, Alis D, Basal S, Sarilar O, Akbulut MF. "Prediction of recurrence in non-muscle invasive bladder cancer patients. Do patient characteristics matter?" J BUON. 2019 Jul-Aug;24(4):1659-1665.

Ozdemir H, Erbin A, Sahan M, Savun M, Cubuk A, Yazici O, Akbulut MF, Sarilar O. "Comparison of supine and prone miniaturized percutaneous nephrolithotomy in the treatment of lower pole, middle pole and renal pelvic stones: A matched pair analysis." Int Braz J Urol. 2019 Sep-Oct;45(5):956-964.

Erbin A, Ucpinar B, Cubuk A, Yazici O, Uysal H, Savun M, Basal S, Akbulut MF. "The Impact of Sheath Size in Miniaturized Percutaneous Nephrolithotomy in Adult Patients; A Matched-pair Analysis." Urol J. 2019 Dec 24;16(6):536-540.

Güler A, Erbin A, Ucpinar B, Savun M, Sarilar O, Akbulut MF. "Comparison of miniaturized percutaneous nephrolithotomy and standard percutaneous nephrolithotomy for the treatment of large kidney stones: a randomized prospective study." Urolithiasis. 2019 Jun;47(3):289-295.

Yanaral F, Ozgor F, Savun M, Agbas A, Akbulut F, Sarilar O. "Shock-wave Lithotripsy for Pediatric Patients: Which Nomogram Can Better Predict Postoperative Outcomes?" Urology. 2018 Jul;117:126-130.

Arslan B, Akbulut MF, Onuk O, Küçüktopçu O, Çilesiz NC, Ozkan A, Yazıcı G. "A comparison of Amplatz dilators and metal dilators for tract dilatation in mini-percutaneous nephrolithotomy." Int Urol Nephrol. 2017 Apr;49(4):581-585.

Akbulut F, Kucuktopcu O, Kandemir E, Ucpinar B, Ozgor F, Simsek A, Arslan B, Erbin A, Yanaral F, Binbay M, Gurbuz G. "Efficacy and safety of mini percutaneous nephrolithotomy in obese patients." Springerplus. 2016 Jul 22;5(1):1148.

Sancak EB, Oguz S, Akbulut T, Uludag A, Akbas A, Kurt O, Akbulut MF. "Female sexual dysfunction in androgenetic alopecia: Case-control study." Can Urol Assoc J. 2016, July;10(7-8):E251-256.

Akbulut F, Kucuktopcu O, Kandemir E, Sonmezay E, Simsek A, Ozgor F, Binbay M, Muslumanoglu AY, Gurbuz G. "Comparison of flexible ureterorenoscopy and mini-percutaneous nephrolithotomy in treatment of lower calyceal stones smaller than 2 cm." Ren Fail. 2016;38(1):163-7.

Tok A, Akbulut F, Buldu I, Karatag T, Kucuktopcu O, Gurbuz G, Istanbulluoglu O, Armagan A, Tepeler A, Tasci AI. "Comparison of microperc and mini-percutaneous nephrolithotomy for medium-sized lower calyx stones." Urolithiasis. 2016 Apr;44(2):155-9.

Akbulut F, Tok A, Penbegul N, Daggulli M, Eryildirim B, Adanur S, Gurbuz G, Celik H, Utangac MM, Dede O, Bodakcı MN, Tepeler A, Sarica K. "Colon perforation related to percutaneous nephrolithotomy: from diagnosis to treatment." Urolithiasis. 2015 Nov;43(6):521-6.

Ozluk Y, Sari S, Guzel NT, Firat P, Akbulut F, Kilicaslan I. "Mixed epithelial and stromal tumor of the kidney with sarcomatous transformation metastatic to the lung: A case report." Anal Quant Cytopathol Histpathol. 2015 Jun;37(3):199-205.

Ozgor F, Kucuktopcu O, Sarilar O, Toptas M, Simsek A, Gurbuz ZG, Akbulut MF, Binbay M. "Does previous open renal surgery or percutaneous nephrolithotomy affect the outcomes and complications of percutaneous nephrolithotomy." Urolithiasis. 2015 Nov;43(6):541-7.

Ugurlu İM, Akman T, Binbay M, Tekinarslan E, Yazıcı Ö, Akbulut MF, Özgör F, Müslümanoğlu AY. "Outcomes of retrograde flexible ureteroscopy and laser lithotripsy for stone disease in patients with anomalous kidneys." Urolithiasis. 2015 Feb;43(1):77-82.

Simsek A, Ozgor F, Kirecci SL, Akbulut MF, Sonmezay E, Yuksel B, Kucuktopcu O, Gurbuz ZG. "Results of tension-free vaginal tape for recurrent stress urinary incontinence after unsuccessful transobturator tape surgery." J Obstet Gynaecol Res. 2014 Jun;40(6):1764-9.

Simsek A, Kirecci SL, Kucuktopcu O, Ozgor F, Akbulut MF, Sarilar O, Ozkuvanci U, Gurbuz ZG. "Comparison of paroxetine and dapoxetine, a novel selective serotonin reuptake inhibitor in the treatment of premature ejaculation." Asian J Androl. 2014 Sep-Oct;16(5):725-7.

Akbulut F, Kucuktopcu O, Sonmezay E, Simsek A, Ozgor F, Gurbuz ZG. "Partial penectomy after debridement of a Fournier's gangrene progressing with an isolated penile necrosis." Ulus Travma Acil Cerrahi Derg. 2014 Sep;20(5):385-8.

Simsek A, Ozgor F, Yuksel B, Kucuktopcu O, Kirecci SL, Toptas M, Sarilar O, Berberoglu AY, Gurbuz ZG, Mimaroglu S, Akbulut F, Baykal M, Arslan B, Savun M, Ucpinar B. "Female sexual function after transobturator tape in women with urodynamic stress urinary incontinence." Springerplus. 2014 Sep 30;3:570.

Akbulut F, Akman T, Salabas E, Dincer M, Ortac M, Kadioglu A. "Neurovascular bundle dissection for Nesbit procedure in congenital penile curvature patients: medial or lateral?" Asian J Androl. 2014 May-Jun;16(3):442-5.

Kadioglu A, Sanli O, Akman T, Canguven O, Aydin M, Akbulut F, Kucukdurmaz F. "Factors Affecting the Degree of Penile Deformity in Peyronie's Disease: An Analysis of 1001 Patients." J Androl. 2011 Sep-Oct;32(5):502-8.

Akman T, Sanli O, Uluocak N, Akbulut F, Nane I, Demir S, Kadioglu A. "The most commonly altered type of Peyronie's disease deformity under oral colchicine treatment is lateral curvature that mostly shifts to the dorsal side." Andrologia. 2011 Feb;43(1):28-33.

Akbulut MF, Sanli O, Kadioglu A. "Editorial Comment on: Are Infertile Men Less Healthy than Fertile Men? Results of a Prospective Case-Control Survey." Eur Urol. 2009 Dec;56(6):1032.

Acar O, Akinci M, Uluocak N, Akbulut F, Kilicaslan I, Gokce O. "Paratesticular metastasis of malignant melanoma: a case report." Kaohsiung J Med Sci. 2008 Jun;24(6):315-8.

Çubuk A, Erbin A, Savun M, Ayranci A, Üçpınar B, Yanaral F, Sarılar Ö, Basal Ş, Akbulut MF. "Autologous transobturator midurethral sling." Turk J Urol. 2018 Dec 21;45(3):230-232.

Sarılar Ö, Özgör F, Küçüktopçu O, Uçpınar B, Akbulut MF, Savun M, Gürbüz ZG, Binbay M. "Is standard percutaneous nephrolithotomy still the standard treatment modality for renal stones less than three centimeters?" Turk J Urol. 2017 Jun;43(2):165-170.

Akbulut F, Savun M, Ucpinar B, Sahan M, Arslan B, Ozgor F, Simsek A, Berberoglu AY, Baykal M, Binbay M. "Duplicated Renal System with H Shaped Ureter: An Extraordinary Anomaly." Case Rep Urol. 2016;2016:4062515.

Akbulut F, Kucuktopcu O, Kandemir E, Sonmezay E, Simsek A, Ucpinar B, Ozgor F, Gurbuz G. "Comparison of efficacy of laser lithotripter with ultrasonic lithotripter in mini percutaneous nephrolithotomy." Arch Ital Urol Androl. 2016 Jan 14;87(4):276-9.

Ozgor F, Simsek A, Aydogdu O, Kucuktopcu O, Sarilar O, Berberoglu AY, Akbulut MF, Binbay M. "Bleeding during laparoscopic partial nephrectomy: Can a hemostatic matrix help to improve hemostasis?"

Marital Status : He is married, his wife is an ophthalmologist, and he is the father of two sons, aged 27 (Medical doctor) and 20 (Student).

Educational Status

1988 Uludağ University Faculty of Medicine / Bursa

1982 Kabataş Boys' High School / Istanbul

1979 Göztepe Secondary School / Istanbul

1976 Harun Reşit Primary School / Istanbul

Institutions he works for

2020 Biruni University Hospital, Head of Urology Department / ISTANBUL
2017 Yeni Yüzyıl University Gaziosmanpaşa Hospital, Head of Urology Department / ISTANBUL

2016 Taksim Training and Research Hospital Urology Clinic Education and Administrative Supervisor / Istanbul

2009 Bağcılar Training and Research Hospital Urology Clinic Chief / Istanbul

2007 International Hospital, Yeşilköy / Istanbul

2007 Ankara Training and Research Hospital 2nd Urology Clinic / Ankara

2001 Military Service, Marshal Fevzi Çakmak Military Hospital / Erzurum

1999 Bergama State Hospital / Izmir

1997 Ankara Training and Research Hospital Specialization Program / Ankara

1992 Izmit State Hospital / Izmit

 

diplomas

2011 Professorship

2006 Associate Professorship

1997 Urology Specialist

1988 Doctor of Medicine

Associations and organizations of which he is a member

European Association of Urology

Turkish Urology Association

Northern Marmara Urology Association

Endourology Association

Nuhoğlu Foundation

Scientific Publications

Author of over 100 publications, presentations and book chapters, 58 of which are international.

Dr. Sılay is an experienced pediatric urologist practicing in Turkey.

Specialty

Assoc. Prof. Selçuk Sılay specializes in robotic surgery for urology conditions in children.

Dr. Selçuk Sılay has provided over:

• 300 pediatric laparoscopic surgeries
• 100 pediatric robotic surgeries
• 300 closed kidney stone surgeries in children.

Work experience

• Since 2018 – Urologist in Memorial Bahçelievler Hospital and Memorial Ataşehir Hospital
• 2017-2018 – Pediatric urology robotic surgery specialist in Mehmet Akif Ersoy Training and Research Hospital
• 2016-2018 – Head of Pediatric Urology Department in Istanbul Medeniyet University Göztepe Training and Research Hospital
• 2011-2016 – Head of Pediatric Urology Department at the Bezmialem Foundation University
• 2009 – Urology Specialist in Diyarbakir Bismil State Hospital
• 2006-2007 – Urology and Robotic Surgery Specialist.

Education

• 1997-2003 – Ankara University Medical School – Degree in general medicine
• 2003 – Baylor College of Medicine (USA) – Training in urology
• 2004-2009 – Istanbul Şişli Hamidiye Etfal Education And Research Hospital – Training in urology
• 2006-2007 – Baylor College of Medicine (USA) – Internship in urology
• 2014-2015 – Texas Children's Hospital (USA) – Pediatric Urology Robotic Surgery Training (USA).

Awards

• 2016 Young Academician of the Year Award by the 24th National Urology Congress in Cyprus
• 2018 Crystal Matula Award as European Academician of the Year.

Scientific activity

Prof. Selçuk Sılay provides research in robotic surgery in children. Has written over 80 articles.

Membership in organizations

• The Turkish Society of Pediatric Urology
• The European Association of Urology
• The European Society for Paediatric Urology
• The Turkish Association of Urology.

Specialties

Kidney and urinary tract endoscopic stone crushing treatment

Endoscopic Prostate and Bladder Surgery (TUR Method)

Diagnosis and surgery of testicular diseases

Diagnosis and treatment of infertility in men (Varicocele surgeries)

Diagnosis and treatment of sexual dysfunctions

Treatment of urinary incontinence in women

Treatment of nocturnal incontinence in children

Treatment of undescended testicle in children

Circumcision

Experience

1995-1999 Bilecik State Hospital Urology Clinic

1999-2002 Kocaeli Gölcük State Hospital Urology Clinic

2002-2006 Sakarya Karasu State Hospital Urology Clinic and Chief Physician

2006-2012 Kocaeli State Hospital Urology Clinic and Chief Physician

2012-2015 Kocaeli State Hospital Urology Clinic

2015-2018 Kocaeli Public Hospitals Secretary General

2018-2021 Kocaeli Provincial Health Director

2021-2023 Kocaeli Darıca Farabi Training and Research Hospital Urology Clinic

2023- 2024 Kocaeli Gölcük Necati Çelik State Hospital Urology Clinic

2024 Private Darıca Büyük Anadolu Hospital

Education

Uludag University Faculty of Medicine (graduation) 1988

Selcuk University Faculty of Medicine (specialization) 1994

1982-1988 Uludağ University Faculty of Medicine

1990 -1994 Selcuk University Faculty of Medicine, Department of Urology (Specialization)

Scientific Publications

Acar A., Sert I. Ü., Gürbüz R., Ergüney Ş: Submucosal methotrexate applications in inoperable bladder tumors.  S.Ü.T.F. Journal. 1993; 9(1):39-41

Acar A., Sert İ.Ü., Gürbüz R., Arslan E.M., Ergüney Ş. , : Bladder wall and prostate

Translated with DeepL.com (free version)

Specializations

RIRS (Laser Stone Breaking in the Kidney)

Open-Closed Prostate Surgeries

Urological Cancer Surgeries

Urinary Incontinence Treatment

Infertility Treatment

Specializations

RIRS (Laser Stone Breaking in the Kidney)

Open-Closed Prostate Surgeries

Urological Cancer Surgeries

Urinary Incontinence Treatment

Infertility Treatment

Specializations

Prostate Diseases Treatment

Kidney, Urinary Tract, Bladder Stone and Tumor Treatment

Infertility, Treatment of Sexual Diseases

Urinary Incontinence Treatment

Circumcision, Undescended Testicle Treatment

• Education Status
•  
• 1988 Uludağ University Faculty of Medicine / Bursa
• 1982 Kabataş Boys’ High School / Istanbul
• 1979 Göztepe Secondary School / Istanbul
• 1976 Harun Reşit Primary School / Istanbul

Institutions: He Works For

• 2020 Biruni University Hospital, Head of Urology Department / ISTANBUL
• 2017 Yeni Yüzyıl University Gaziosmanpaşa Hospital, Head of Urology Department / İSTANBUL
• 2016 Taksim Training and Research Hospital Urolog Clinic Education and Administrative Supervisor / Istanbul
• 2009 Bağcılar Training and Research Hospital Urology Clinic Chief / Istanbul
• 2007 International Hospital, Yeşilköy / Istanbul
• 2007 Ankara Training and Research Hospital 2nd Urology Clinic / Ankara
• 2001 Military Service, Marshal Fevzi Çakmak Military Hospital / Erzurum
• 1999 Bergama State Hospital / Izmir
• 1997 Ankara Training and Research Hospital Specialization Program / Ankara
• 1992 Izmit State Hospital / Izmit

Diplomas

• 2011 Professorship
• 2006 Associate Professorship
• 1997 Urology Specialist
• 1988 Doctor of Medicine

Education:

Medical Degree: Çukurova University Faculty of Medicine (1993)

Specialization in Urology: Şişli Etfal Training and Research Hospital (2005)

Professional Experience:

Current Position: Practicing at İstinye University Hospital Medical Park Gaziosmanpaşa, Istanbul

Past Experience: Extensive work in both public and private healthcare sectors, including significant contributions at Istanbul İstinye University Health Practice and Research Center.

Areas of Interest:

Pediatric Urology

Urogynecology

Treatment of pediatric urology disorders

Urological surgeries and procedures

Professional Memberships:

Member of several prestigious medical societies, including the Turkish Medical Association, European Society of Pediatric Urology, and the Turkish Society of Pediatric Urology.

Certifications:

Dr. Güllüoğlu has completed numerous certifications and advanced training programs, reflecting his commitment to continuous professional development and staying at the forefront of urological advancements.

Prof. Dr. Berkan Reşorlu was born in 1979 in Ankara. He completed his Medical Education in Ankara University between 1997-2003. Between 2003-2008, he completed his residency in Urology at Ankara University Faculty of Medicine and became a Urology Specialist. He has carried out many international studies after his specialization, has contributed significantly to the literature by publishing more than 110 articles in international journals with SCI / SCI-E index, and in 2013 he received the title of Associate Professor, in 2022 he received the title of Professor.

Personal information

Title: Associate Professor

Branch: Urology

Work History:

1 Istanbul Ümraniye Training and Research Hospital

2 Kars State Hospital

3 Çatalca İlyas Çokay State Hospital

4 Istanbul Bilim University Faculty of Medicine Urology Clinic

5 Gayrettepe Florence Nightinagle Hospital

Medical Specialties and Subspecialties:

Laparoscopic Surgery

Education

2007 - Istanbul University Cerrahpaşa Faculty of Medicine

2012 - Istanbul Ümraniye Training and Research Hospital (Specialization)

Education:

1997 – 2003    Hacettepe University

2004 – 2009     Ankara Dışkapı Training and Research Hospital

2016 – 2019     Afyon Kocatepe University

Experience:

2022 – Still       Lokman Hekim Akay Hospital

2019 – 2022     Private Meddem Hospital

2018 – 2019      Afyon Kocatepe University

2015 – 2018      Afyon Kocatepe University

2012 – 2015      Bozok University Faculty of Medicine

2010 – 2012     Ankara Dışkapı Training and Research Hospital

2009 – 2010      TSK Rehabilitation and Care Center Presidency

2004 – 2009     Ankara Dışkapı Training and Research Hospital