As a urology specialist providing medical services, Prof. Dr. Hasan Biri graduated from Ankara University Faculty of Medicine in 1987. He started his residency in urology at Gazi University Hospital in 1987 and completed his specialization in 1992, becoming a urology specialist. Dr. Biri completed his compulsory service between 1993-1995. In 1995, he was appointed as an assistant professor at Gazi University Faculty of Medicine. Between 1997-1998, he participated in research in many areas of uro-oncology such as radical prostatectomy and radical cystectomy at the University of Southern California Kneed Norris Uro-oncology Center, and was involved in many clinical practices. He successfully passed the associate professorship exam in 1998 and continued his education and training activities as an associate professor at Gazi University. Between 2000-2003, he served as the head of urology and chief physician at Gazi Ankara Hospital. In 2004, he became a professor at Gazi University Faculty of Medicine. Throughout his academic career, he has published over 80 national and international publications and presented papers. As the founding president of Koru Healthcare Group, Prof. Dr. Hasan Biri currently provides medical services to his patients at Özel Koru Ankara Hospital. Prof. Dr. Hasan Biri is particularly specialized in robotic surgery, and his medical interests include:
• Uro-oncology
· Prostate Cancer
· Bladder Cancer
· Kidney Cancer
· Testicular Cancer
• Andrology
• Robotic Surgery (Prostate, Bladder, Kidney, Renal Artery Stenosis)
• Endourology
• Benign Prostatic Hyperplasia
• Kidney Stone Disease
• Infertility.
PROFESSIONAL EXPERIENCE
2011-2012
Erzurum Koprukoyu State Hospital
Department: General Medicine
2012-2017
Istanbul University Cerrahpaşa Medical Faculty
Department: Internal Medicine
06/2017-10/2017
Istanbul Gaziosmanpasa Taksim Training and Research Hospital
Department: Internal Medicine
10/2017-11/2018
Istanbul University Istanbul Medical Faculty
Department: Allergy and Immunology Fellowship
2018/2022
Istanbul University Oncology Institute
Department: Medical Oncology Fellowship
2022-2023
Tekirdag City Hospital
Department: Medical Oncology Specialist
2023-present
Istanbul Medipol University Medipol Bahcelievler Private Hospital
Department: Medical Oncology Assoc. Prof.
EDUCATION
2005-2011
Medical Education
Sivas Cumhuriyet University Medical Faculty, Sivas, Turkey
2012-2017
Internal Medicine
Istanbul University Cerrahpaşa Medical Faculty, Department of Internal Medicine, Istanbul, Turkey
2017-2018
Allergy-Immunology Fellowship
Istanbul University Istanbul Medical Faculty
Department of Internal Medicine, Division of Allergy and Immunology, Istanbul, Turkey
2018-2022
Medical Oncology Fellowship
Istanbul University Oncology Institute, Department of Medical Oncology, Istanbul, Turkey
2022
ESMO Board Certification in Medical Oncology
10th September 2022 in Paris, France.
2023
Medical Oncology Assoc. Prof.
Istanbul Medipol University Department of Medical Oncology, Istanbul, Turkey
INTERNATIONAL CLINICAL TRIALS:
1. Astefania - ROCHE
2. PFİZER
3. RECITE - AMGEN
4. NAVIGATE - BAYER
5. RUBY - Tesaro (PRA)
6. ENGOT-ov43/GOG-3036 - MSD
7. ASTRA ZENECA
8. ROSY-O - ASTRA ZENECA
INTERNATIONAL PUBLICATIONS
I. Published journal articles indexed by SCI, SSCI, and AHCI
Weekly Paclitaxel in Classic Kaposi Sarcoma
Carboplatin Desensitization in Ovarian Carcinoma
High-Dose Chemotherapy for Ewing’s Sarcoma
Multidrug Refractory TFE3(+) Renal Cell Carcinoma
Crizotinib Efficacy in NSCLC with MET Alterations
Clinicopathological Features in ALK Mutant NSCLC
PSMA-Based Tumor Burden in Prostate Cancer
Atezolizumab in Metastatic Urothelial Carcinoma
Pulmonary Sarcomatoid Carcinoma
Prognostic Factors in Atezolizumab-Treated Urothelial Carcinoma
Atezolizumab with Chemotherapy in Small Cell Lung Cancer
FOLFIRINOX vs. Gemcitabine + Nab-Paclitaxel in Pancreatic Cancer
Trastuzumab Emtansine in Older HER2-Positive Breast Cancer Patients
Real-Life Efficacy of Osimertinib in Advanced NSCLC
ALK-Positive Cells Percentage and Alectinib Efficacy
Real-World Data on Alectinib in ALK-Positive NSCLC
Prognostic Factors in Metastatic RCC with T790M Mutation
FLOT Regimen in Metastatic Gastric Cancer
Desensitization Protocol in Lenalidomide Hypersensitivity Reactions
Factors Associated with Diagnostic Skin Test Positivity in PPI Hypersensitivity
Efficacy of Capecitabine and Temozolomide in Neuroendocrine Tumors
Subsequent Treatments in Hormone-Positive Breast Cancer Progression
Termination of Trastuzumab in HER2-Positive Metastatic Breast Cancer
Long-term Outcomes and Predictors of Recurrence in Node-Negative Early Stage Breast Cancer
Prognostic Factors Influencing PFS in HER2-Positive Metastatic Breast Cancer
Treatment Efficacy of Ribociclib or Palbociclib plus Letrozole in Metastatic Breast Cancer
Efficacy and Safety of Sorafenib in Adult Metastatic Osteosarcoma Patients
Single-Agent Temozolomide as Salvage Therapy in Heavily Pretreated Metastatic Sarcoma Patients
Outcomes and Prognostic Factors in Metastatic Renal Cell Carcinoma with Brain Metastases
FLOT Regimen in First-Line Treatment of Metastatic Gastric Cancer
Prognostic Factors of Perioperative FLOT Regimen in Operable Gastric Cancer
Efficacy and Outcomes of Systemic Chemotherapy in Posttransplant Kaposi Sarcoma
Comparison of Second-Line Treatments in Metastatic Renal Cell Carcinoma
Toxicity Management and Effectiveness of Regorafenib in Advance GIST Patients: A Real-world Study - Authors: Paksoy, N., Ferhatoğlu, F., Doğan, İ., Khanmammadov, N., Bozbey, H. U., Karabulut, S., & Taştekin, D. - Journal: TURKISH JOURNAL OF ONCOLOGY, 1(1)
Demographic and Clinical Features and Factors Associated with Survival in Patients with Primary Glomerulonephritis: Single Tertiary Center Experience - Authors: Paksoy, N., Trabulus, S., Seyahi, N., & Altiparmak, M. R. - Journal: Namik Kemal Tip Dergisi, 11(1)
Efficacy of Sorafenib in Symptomatic Patients with Pretreated Progressive Desmoid Tumors - Authors: Paksoy, N., Ferhatoglu, F., Dogan, I., Ak, N., Pehlivan, M., Ekenel, M., & Basaran, M.
Nodal Response to Neoadjuvant Chemotherapy is a Better Predictive Factor of Survival Than Miller-Payne Scoring in Breast Cancer - Authors: Ak, Naziye, et al. - Journal: Journal of Oncological Sciences, 7.2: 42-49
Evaluation of Prognostic and Predictive Values of Hemogram Parameters in Patients with Advanced Stage Ovarian Carcinoma - Authors: Ak, Naziye, et al. - Journal: Turkish Journal of Oncology/Türk Onkoloji Dergisi, 2021, 36.4
Identifying Risk Factors Associated with Survival and Drug-Related Toxicities in Imatinib-Resistant Gastrointestinal Stromal Tumor (GIST) Patients Treated with Sunitinib - Authors: Ferhatoglu, F., Karabulut, S., Paksoy, N., & Tastekin, D.
Real-life Outcomes of ROS1 Fusion-positive Metastatic Lung Cancer Patients who were Treated with Crizotinib - Authors: Dogan, İ., Khanmammadov, N., Paksoy, N., Ferhatoglu, F., Aydın, E., Vatansever, S., & Aydine, A. - Journal: TURK ONKOLOJI DERGISI-TURKISH JOURNAL OF ONCOLOGY
Predictors of the acquisition of T790M mutation in EGFR-mutant metastatic lung cancer patients who were treated with EGFR inhibitors - Authors: Dogan, I., Khanmammadov, N., Paksoy, N., Vatansever, S., Saip, P., & Aydıner, A. - Journal: Eurasian Journal of Pulmonology
Laterality of Adrenal Gland Metastasis in Lung Cancer: Results of a Comparative Study - Authors: Ferhatoglu, F., Gagatay, T., Okumus, G., Aydiner, A., Paksoy, N., Ak, N., ... & Saip, P. - Journal: Eurasian Journal of Medical Investigation, 7(2)
Poor Risk Factors Affecting Cancer Patients Infected with Covid-19: A Retrospective Comparative Study from a Pandemic Hospital - Authors: Ferhatoglu, F., Kapağan, T., Paksoy, N., Ak, N., Medetalibeyoğlu, A., Şenkal, N., ... & Vatansever, S. - Journal: Turk Onkoloji Dergisi, 38(1)
Systemic Treatment Outcomes of Progressive Medullary Thyroid Carcinoma from the Registries of a Tertiary Cancer Center - Authors: Ferhatoglu, F., Paksoy, N., & Başaran, M. - Journal: Namik Kemal Tip Dergisi, 10(4)
Evaluation of clinical features and risk factors related to late recurrence (> 5 years) in patients with breast cancer - Authors: Ferhatoglu, F., Aydiner, A., & Paksoy, N. - Journal: Journal of Surgery & Medicine (JOSAM), 6(12)
Assessing the Clinical Impact of Lutetium-177 DOTATATE Peptide Receptor Radionuclide Therapy (PRRT) on Metastatic Neuroendocrine Tumors: A Multicenter Real-World Data from Türkiye
Thesis:
Istanbul University Cerrahpaşa Medical Faculty, Internal Medicine Department PAKSOY, Nail. Demographical, clinical characteristics and survival factors in patients withprimary glomerulonephritis: Cerrahpasa Medical Faculty Experience. (2016)
International Refereed Congress / Symposium Publications in Proceedings (ASCO/ESMO Abstracts)
Prognostic factors influencing progression-free survival in HER2 positive metastatic breast cancer patients who treated with lapatinib and capecitabine combination
Efficacy of regorafenib and 5-fluorouracil-based rechallenge treatment in the third-line treatment of metastatic colorectal cancer: A Turkish oncology group study
Long-term outcomes and predictors of recurrence in patients with early-stage node-negative breast cancer
Efficacy of temozolomide in pretreated patients with metastatic sarcoma
Efficacy of sorafenib in symptomatic patients with pretreated progressive desmoid tumors
Efficacy of sorafenib in heavily pretreated adult patients with metastatic osteosarcoma
Outcomes and prognostic factors in metastatic renal cell carcinoma patients with brain metastases
Association of response to first-line chemotherapy with the efficacy of atezolizumab in patients with metastatic urothelial carcinoma
Safety and survival in adult women with platinum-sensitive relapsed BRCA mutant ovarian cancer: A study of patients in Olaparib Turkey Early Access Program—LynTurk study
Atezolizumab in patients with metastatic urothelial carcinoma who have progressed after first-line chemotherapy: Results of real-life experiences
Experience
2017 - 2022 Haseki Training and Research Hospital, Associate Professor
2017 - 2022 Haseki Training and Research Hospital
2013 - 2017 Haseki Training and Research Hospital
2013 - 2017 Haseki Training and Research Hospital, Chief Resident
2010 - 2013 Silivri State Hospital (Compulsory Service Obligation)
2008 - 2008 University of Michigan Medical School
2005 - 2010 Istanbul Medical Faculty, Department of Urology
Education
2010 Istanbul University, Istanbul Medical Faculty, Department of Urology
2004 Istanbul University, Istanbul Medical Faculty
Publications
International Peer-Reviewed Journals:
Culpan M, Atis G, Sanli O, Bozkurt Y, Atmaca AF, Semerci B, Kutsal C, Canda AE, Akbulut F, Tugcu V, Boylu U, Erturhan S, Koca O, Ateş F, Halis F, Soyupek S, Turna B, Cakmak S, Sahin S, Erdem S, Yildirim A. "Comparison of Tumor Enucleation and Standard Partial Nephrectomy According to Trifecta Outcomes: A Multicenter Study by the Turkish Academy of Urology, Uro-Oncology Working Group." J Invest Surg. 2022 May;35(5):1112-1118.
Sahan M, Sarilar O, Akbulut MF, Demir E, Savun M, Sen O, Ozgor F. "Flexible ureterorenoscopy and laser lithotripsy with regional anesthesia vs general anesthesia: A prospective randomized study." Int Braz J Urol. 2020 Nov-Dec;46(6):1010-1018.
Cubuk A, Yanaral F, Savun M, Ayranci A, Erbin A, Yazici O, Akbulut MF, Sarilar O. "Modified autologous transobturator tape surgery - evaluation of short-term results." Ginekol Pol. 2020;91(2):51-56.
Kandemir E, Savun M, Sezer A, Erbin A, Akbulut MF, Sarilar Ö. "Comparison of Miniaturized Percutaneous Nephrolithotomy and Standard Percutaneous Nephrolithotomy in Secondary Patients: A Randomized Prospective Study." J Endourol. 2020 Jan;34(1):26-32.
Ucpinar B, Erbin A, Ayranci A, Caglar U, Alis D, Basal S, Sarilar O, Akbulut MF. "Prediction of recurrence in non-muscle invasive bladder cancer patients. Do patient characteristics matter?" J BUON. 2019 Jul-Aug;24(4):1659-1665.
Ozdemir H, Erbin A, Sahan M, Savun M, Cubuk A, Yazici O, Akbulut MF, Sarilar O. "Comparison of supine and prone miniaturized percutaneous nephrolithotomy in the treatment of lower pole, middle pole and renal pelvic stones: A matched pair analysis." Int Braz J Urol. 2019 Sep-Oct;45(5):956-964.
Erbin A, Ucpinar B, Cubuk A, Yazici O, Uysal H, Savun M, Basal S, Akbulut MF. "The Impact of Sheath Size in Miniaturized Percutaneous Nephrolithotomy in Adult Patients; A Matched-pair Analysis." Urol J. 2019 Dec 24;16(6):536-540.
Güler A, Erbin A, Ucpinar B, Savun M, Sarilar O, Akbulut MF. "Comparison of miniaturized percutaneous nephrolithotomy and standard percutaneous nephrolithotomy for the treatment of large kidney stones: a randomized prospective study." Urolithiasis. 2019 Jun;47(3):289-295.
Yanaral F, Ozgor F, Savun M, Agbas A, Akbulut F, Sarilar O. "Shock-wave Lithotripsy for Pediatric Patients: Which Nomogram Can Better Predict Postoperative Outcomes?" Urology. 2018 Jul;117:126-130.
Arslan B, Akbulut MF, Onuk O, Küçüktopçu O, Çilesiz NC, Ozkan A, Yazıcı G. "A comparison of Amplatz dilators and metal dilators for tract dilatation in mini-percutaneous nephrolithotomy." Int Urol Nephrol. 2017 Apr;49(4):581-585.
Akbulut F, Kucuktopcu O, Kandemir E, Ucpinar B, Ozgor F, Simsek A, Arslan B, Erbin A, Yanaral F, Binbay M, Gurbuz G. "Efficacy and safety of mini percutaneous nephrolithotomy in obese patients." Springerplus. 2016 Jul 22;5(1):1148.
Sancak EB, Oguz S, Akbulut T, Uludag A, Akbas A, Kurt O, Akbulut MF. "Female sexual dysfunction in androgenetic alopecia: Case-control study." Can Urol Assoc J. 2016, July;10(7-8):E251-256.
Akbulut F, Kucuktopcu O, Kandemir E, Sonmezay E, Simsek A, Ozgor F, Binbay M, Muslumanoglu AY, Gurbuz G. "Comparison of flexible ureterorenoscopy and mini-percutaneous nephrolithotomy in treatment of lower calyceal stones smaller than 2 cm." Ren Fail. 2016;38(1):163-7.
Tok A, Akbulut F, Buldu I, Karatag T, Kucuktopcu O, Gurbuz G, Istanbulluoglu O, Armagan A, Tepeler A, Tasci AI. "Comparison of microperc and mini-percutaneous nephrolithotomy for medium-sized lower calyx stones." Urolithiasis. 2016 Apr;44(2):155-9.
Akbulut F, Tok A, Penbegul N, Daggulli M, Eryildirim B, Adanur S, Gurbuz G, Celik H, Utangac MM, Dede O, Bodakcı MN, Tepeler A, Sarica K. "Colon perforation related to percutaneous nephrolithotomy: from diagnosis to treatment." Urolithiasis. 2015 Nov;43(6):521-6.
Ozluk Y, Sari S, Guzel NT, Firat P, Akbulut F, Kilicaslan I. "Mixed epithelial and stromal tumor of the kidney with sarcomatous transformation metastatic to the lung: A case report." Anal Quant Cytopathol Histpathol. 2015 Jun;37(3):199-205.
Ozgor F, Kucuktopcu O, Sarilar O, Toptas M, Simsek A, Gurbuz ZG, Akbulut MF, Binbay M. "Does previous open renal surgery or percutaneous nephrolithotomy affect the outcomes and complications of percutaneous nephrolithotomy." Urolithiasis. 2015 Nov;43(6):541-7.
Ugurlu İM, Akman T, Binbay M, Tekinarslan E, Yazıcı Ö, Akbulut MF, Özgör F, Müslümanoğlu AY. "Outcomes of retrograde flexible ureteroscopy and laser lithotripsy for stone disease in patients with anomalous kidneys." Urolithiasis. 2015 Feb;43(1):77-82.
Simsek A, Ozgor F, Kirecci SL, Akbulut MF, Sonmezay E, Yuksel B, Kucuktopcu O, Gurbuz ZG. "Results of tension-free vaginal tape for recurrent stress urinary incontinence after unsuccessful transobturator tape surgery." J Obstet Gynaecol Res. 2014 Jun;40(6):1764-9.
Simsek A, Kirecci SL, Kucuktopcu O, Ozgor F, Akbulut MF, Sarilar O, Ozkuvanci U, Gurbuz ZG. "Comparison of paroxetine and dapoxetine, a novel selective serotonin reuptake inhibitor in the treatment of premature ejaculation." Asian J Androl. 2014 Sep-Oct;16(5):725-7.
Akbulut F, Kucuktopcu O, Sonmezay E, Simsek A, Ozgor F, Gurbuz ZG. "Partial penectomy after debridement of a Fournier's gangrene progressing with an isolated penile necrosis." Ulus Travma Acil Cerrahi Derg. 2014 Sep;20(5):385-8.
Simsek A, Ozgor F, Yuksel B, Kucuktopcu O, Kirecci SL, Toptas M, Sarilar O, Berberoglu AY, Gurbuz ZG, Mimaroglu S, Akbulut F, Baykal M, Arslan B, Savun M, Ucpinar B. "Female sexual function after transobturator tape in women with urodynamic stress urinary incontinence." Springerplus. 2014 Sep 30;3:570.
Akbulut F, Akman T, Salabas E, Dincer M, Ortac M, Kadioglu A. "Neurovascular bundle dissection for Nesbit procedure in congenital penile curvature patients: medial or lateral?" Asian J Androl. 2014 May-Jun;16(3):442-5.
Kadioglu A, Sanli O, Akman T, Canguven O, Aydin M, Akbulut F, Kucukdurmaz F. "Factors Affecting the Degree of Penile Deformity in Peyronie's Disease: An Analysis of 1001 Patients." J Androl. 2011 Sep-Oct;32(5):502-8.
Akman T, Sanli O, Uluocak N, Akbulut F, Nane I, Demir S, Kadioglu A. "The most commonly altered type of Peyronie's disease deformity under oral colchicine treatment is lateral curvature that mostly shifts to the dorsal side." Andrologia. 2011 Feb;43(1):28-33.
Akbulut MF, Sanli O, Kadioglu A. "Editorial Comment on: Are Infertile Men Less Healthy than Fertile Men? Results of a Prospective Case-Control Survey." Eur Urol. 2009 Dec;56(6):1032.
Acar O, Akinci M, Uluocak N, Akbulut F, Kilicaslan I, Gokce O. "Paratesticular metastasis of malignant melanoma: a case report." Kaohsiung J Med Sci. 2008 Jun;24(6):315-8.
Çubuk A, Erbin A, Savun M, Ayranci A, Üçpınar B, Yanaral F, Sarılar Ö, Basal Ş, Akbulut MF. "Autologous transobturator midurethral sling." Turk J Urol. 2018 Dec 21;45(3):230-232.
Sarılar Ö, Özgör F, Küçüktopçu O, Uçpınar B, Akbulut MF, Savun M, Gürbüz ZG, Binbay M. "Is standard percutaneous nephrolithotomy still the standard treatment modality for renal stones less than three centimeters?" Turk J Urol. 2017 Jun;43(2):165-170.
Akbulut F, Savun M, Ucpinar B, Sahan M, Arslan B, Ozgor F, Simsek A, Berberoglu AY, Baykal M, Binbay M. "Duplicated Renal System with H Shaped Ureter: An Extraordinary Anomaly." Case Rep Urol. 2016;2016:4062515.
Akbulut F, Kucuktopcu O, Kandemir E, Sonmezay E, Simsek A, Ucpinar B, Ozgor F, Gurbuz G. "Comparison of efficacy of laser lithotripter with ultrasonic lithotripter in mini percutaneous nephrolithotomy." Arch Ital Urol Androl. 2016 Jan 14;87(4):276-9.
Ozgor F, Simsek A, Aydogdu O, Kucuktopcu O, Sarilar O, Berberoglu AY, Akbulut MF, Binbay M. "Bleeding during laparoscopic partial nephrectomy: Can a hemostatic matrix help to improve hemostasis?"
2011 – 2015, (Internal Medicine Specialist) Istanbul University Istanbul School of Education and Career
Medicine Department of Internal Medicine
2015 – 2016, (Internal Medicine) Specialist Istanbul Haydarpasa Numune Training and Research Hospital
2016 – 2019, (Medical Oncology) Istanbul University Istanbul School of Medicine Department of Medical Oncology
2019 – 2021, (Medical Oncology Specialist) - Istanbul Haydarpasa Numune Training and Research Hospital
2021 – 2024, (Associate Professor) Marmara University School of Medicine Department of Medical Oncology
Memberships in Scientific Organizations
ASCO
ESMO
TTOD
AVOD
Publications
In the field of oncology, he has published over 30 peer-reviewed articles at both international and national levels.
Awards Received
EAACI The European Academy of Allergy and Clinical Immunology 2019 Best Poster Award
"The top 3rd verbal presentation, IGICC (11th International Gastrointestinal Cancers Conference – IGICC2021)"
Speeches Delivered at National Congresses, Conferences, and Symposia:
Courses, Meetings, and Certificates
ESMO certified Medical Oncologist since 2019
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