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Best Countries & Costs for Xofigo Radium-223 in the World

The best countries for Xofigo Radium-223 in the world are Turkey, Germany, Israel, , and . All five combine accredited hospitals, experienced surgeons, and procedure costs up to 90% lower than in the US. Bookimed's ranking is based on 63 patient requests and 12 verified clinics across 50+ countries.

Save up to

90%

vs. average UK or US prices

Data from 12 verified clinics across 30 countries
Meet the experts behind this page

Medically reviewed by

Fahad Mawlood
Medical Editor & Data Scientist
Authored by Anna Leonova
Head of Content Marketing Team
Clinics in :
Turkey Germany

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We've transformed the clinic search process, making it simple, fast, and personal.
Answer a few questionsTake a short quiz to share your Xofigo Radium-223 goals.
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Choose the best optionCompare offers and choose the clinic that suits you best.
You can also browse all 12 clinics below.

How Much Does Xofigo Radium-223 Cost?

The average price of Xofigo Radium-223 is $12,957, the minimum price is $12,957, and the maximum price is $12,957.
TurkeyAustriaSpain
Xofigo Radium-223from $7,000from $20,000from $14,000
Data verified by Bookimed as of May 2026, based on patient requests and official quotes from 12 clinics worldwide. Median costs are based on real invoices (2025–2026) and updated monthly. Actual prices may vary.

Turkey: Best Country for Xofigo Radium-223 in the World – from $7,000

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Germany: Top Country for Xofigo Radium-223 Abroad – from $50,000

Germany serves as a global hub for Xofigo Radium-223 due to its specialized nuclear medicine infrastructure. Major centers concentrate on alpha-particle therapy to treat prostate cancer that has spread to bones. Treatment helps reduce bone pain while sparing healthy tissue from radiation damage.

  • Surgical volume. German centers manage massive patient loads. Bremen-Mitte Clinic treats 40,000+ patients annually across 38 departments.
  • Nuclear medicine expertise. Facilities often use the Siemens Biograph mCT for precise cancer cell targeting and monitoring.
  • Strict quality standards. Clinics maintain ISO certification and high Focus magazine rankings for oncology care excellence.
  • Treatment costs. Total care packages for six cycles range from $50,000 to $80,000.

Bookimed Expert Insight: German clinics often structure Xofigo care as outpatient therapy. This allows patients to undergo treatment without long hospital stays. Coordination teams at centers like Bremen-Mitte Clinic handle scheduling quickly. This efficiency is vital because metastatic cancer requires timely intervention to be effective.

What patients say: Patients note that Germany offers incredibly efficient scheduling for radiopharmaceuticals. They are often surprised by how quickly they can start treatment compared to other countries. The facilities are modern, and the coordination makes navigating specialized nuclear medicine much easier.

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Israel: Top Country for Xofigo Radium-223 Abroad – from $7,800

Israel provides targeted oncology care with radioactive Radium-223 for patients with metastatic prostate cancer. Specialized clinics combine molecular radiotherapy with precise diagnostic scans to locate bone metastases. Treatment focus remains on prolonging life and reducing severe pain while protecting healthy surrounding bone marrow cells.

  • Precision cost. Treatment typically costs from $7,800 to $10,500 at major medical centers.
  • Expert surgical oversight. Specialists like Dr. Ofer Merimsky have 30+ years of clinical and academic oncology experience.
  • Safe radiation protocols. JCI-certified hospitals like Sourasky perform 34,000+ operations annually under strict international safety standards.
  • High success benchmarks. Top oncological departments in Tel Aviv maintain an average 90% success rate for treatments.

Bookimed Expert Insight: Israeli hospitals often couple Xofigo with PET/CT PSMA scans to ensure the medicine reaches every lesion. This detailed mapping helps doctors at facilities like Sourasky precisely track how well the treatment is working. It is a highly coordinated process involving nuclear medicine and oncology teams.

What patients say: Patients note the medical coordinators in Israel make the logistics of radioactive treatments feel manageable. They often describe the hospital environment as deeply professional and supportive during intensive therapies. Many emphasize that doctors here take extra time to explain how alpha particles target only bone tumors.

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How Bookimed Ranks the Best Affordable Countries for Xofigo Radium-223 Abroad

Transparent methodology - so you can trust our recommendations.

Whether you're looking for the cheapest place to get xofigo radium-223 or the highest-rated specialists abroad, Bookimed's ranking accounts for everything that matters. It uses a smart algorithm that continuously analyzes real-world data from verified verified clinics worldwide, including:

  • 63 patient requests

    We analyze thousands of real cases to identify destinations with the highest patient demand and best outcomes for xofigo radium-223.

  • 20 verified patient reviews

    Real feedback on hospital facilities, staff communication, recovery experience, and long-term results.

  • Accreditation standards

    International accreditations such as JCI and ISO 9001, or equivalent national certifications, verified annually.

  • Board-certified specialists

    Evaluated by credentials, volume of successful cases for xofigo radium-223, and specialized training.

  • Transparent price data

    Aggregated directly from clinics and cross-checked against other ranking criteria - so the cheapest countries for xofigo radium-223 on our list are also among the safest.

  • Medical excellence & innovation

    We prioritize countries using the latest techniques and equipment for xofigo radium-223, with proven track records in international patient care.

Choosing a country for Xofigo Radium-223 abroad shouldn't come down to guesswork. Having helped over 900,000 patients, we know which destinations combine the best specialists, safest hospitals, and affordable prices. We're here to help you find the right one.

Why we?

Your personal Bookimed medical coordinator

  • Supports you at every stage
  • Helps choose the right clinic and doctor
  • Ensures quick and convenient access to information
Authored by
Anna Leonova
Anna Leonova
Head of Content Marketing Team
A certified medical writer with 10+ years of experience, developed Bookimed’s trusted content, backed by a Master’s in Philology and medical expert interviews worldwide.
Anna Leonova Linkedin
Reviewed by Bookimed Medical Advisor
Fahad Mawlood
Medical Editor & Data Scientist
General practitioner. Winner of 4 scientific awards. Served in Western Asia. Former Team Leader of a medical team supporting Arabic-speaking patients. Now responsible for data processing and medical content accuracy.
Fahad Mawlood Linkedin

All You Need to Know about Xofigo Radium-223

What is radium-223 (Xofigo)?

Radium-223 is a kind of internal radiotherapy to treat metastases in the bones caused by prostate cancer. Xofigo is a brand name that produces radium-223.

Xofigo mechanism of action is the following: radium-223 affects bone cancer cells. This radioactive agent is similar to calcium, so it is absorbed by bones. As a result, cancer cells, located in the bones, are directly destroyed by radium-223 (Xofigo) radiation.

How is radium-223 (Xofigo) for prostate cancer used?

  1. A patient arrives to a hospital, undergoes diagnostic procedure to determine a dose of Xofigo injections.
  2. The medical center orders radium-223 (Xofigo). The delivery of the drug takes about 1 week. The therapy starts.
  3. Radium-223 (Xofigo) is a radioactive agent administered intravenously. A doctor puts a thin cannula in the vein during a treatment session. It takes about 1 minute.

The Xofigo injection is repeated every 4 weeks. The maximum number of injections is 6. The procedure is outpatient — you leave the hospital immediately after the injection. A patient can stay in the country for this period or to return home after injection.

To control a patient's health condition, blood tests are required between treatment sessions.

When is radium-223 (Xofigo) indicated?

Radium-223 (Xofigo) injection is indicated in case:

  • when surgical or hormonal treatments are ineffective for prostate cancer no longer
  • cancer (metastases) has spread to the bones but not other parts of the body
  • a patient has not been treated by Abiraterone (a hormonal therapy drug). The following treatment with radium-223, in this case, increases the risk of bone fractures.

Among the contraindications to radium-223 (Xofigo) for prostate cancer treatment may be:

Bone marrow pathologies/problems — radium-223 (Xofigo) can provoke lowering blood cells down. In this case, a patient will need a blood transfusion. Previous or current treatment with chemotherapy or extensive radiotherapy. Other abnormal health conditions.

Only a doctor can determine whether radium-223 (Xofigo) is adequate prostate cancer treatment in your case and estimate possible risks.

What are the side effects of radium-223 for prostate cancer?

Radium-223 (Xofigo) may cause such side effects:

  • diarrhea
  • nausea
  • swelling in the extremities
  • vomiting
  • reduced blood cells counts
  • pain in bones.

In most of the cases, side effects are mild. But do not hesitate to tell your doctor if some of them occur.

What are the recommendations after prostate cancer treatment with radium-223?

A doctor will give you recommendations specific for your case, however there some universal advice:

  • drink a lot of water for a few days after treatment to speed up radiation withdrawing from your body
  • wash the hands carefully every time you visit a toilet
  • wash your underwear separately to avoid radiation spread.

You need to follow this advice for several days during the treatment with radium-223.

What is the price for radium-223?

Radium-223 (Xofigo) cost is considered quite high compared to prostatectomy, HIFU, or brachytherapy prices, for instance.

However, radium-223 is the only treatment option that can prolong a patient's life in case of prostate cancer stage 4 with metastases in the bones.

The cost of radium-223 (Xofigo) is pointed for an injection. Only a doctor can determine how many doses a patient needs after diagnostic procedures.

Compare the prices for radium-223 (Xofigo) in the hospitals listed on this page.

You can always get a personalized quote by filling out a form on Bookimed. This option is free.

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