CAR-T Therapy for Acute Lymphoblastic Leukemia (ALL) at Sheba Medical Center
What's included in this package
Medical Procedures
- CAR T-cell therapy
- Post-operative care
- 3 meals per day by nutritionist
- 24-hr nurse services
- CT Scan
- Electrocardiogram (ECG)
- Consultation with a doctor
- Preoperative tests
- Blood tests
- Follow-up examination
- Biochemistry blood test
- PET/CT
- Consultation with an oncologist
- Consultation with a hematologist
- Consultation with an immunologist
- Consultation with a pediatric hematologist
- Сonsultation with an oncohematologist
- Biopsy
- Complete blood count with cancer markers and a proteinogram
- CT angiography
Duration
- 21 days in the hospital
Accommodation
Hospitalization
Transport
Transfer airport-clinic-airport
Additional information
CAR-T Therapy for Acute Lymphoblastic Leukemia (ALL) at Sheba Medical Center
For patients diagnosed with Acute Lymphoblastic Leukemia (ALL), especially those with relapsed or treatment-resistant disease, access to advanced therapy can be life-changing.
Sheba Medical Center, ranked among the World's Top 10 Hospitals by Newsweek 2026, offers state-of-the-art CAR-T cell therapy, providing new hope where conventional treatments may no longer be effective.
Sheba Medical Center is internationally recognized for its expertise in advanced cellular therapies, including CAR-T therapy for ALL, particularly in pediatric and young adult patients, combining cutting-edge science with extensive clinical experience.
A Faster Path to Life-Saving Treatment
At Sheba, the entire CAR-T process is performed on-site, ensuring speed, precision, and optimal cell quality, critical in fast-progressing diseases like ALL.
• Apheresis – collection of the patient’s T-cells
• Cell Engineering – genetic modification at Sheba’s Advanced Biotherapy Center
• Infusion – reinfusion of modified cells designed to target and eliminate leukemia cells
By keeping the entire process in-house, treatment can begin in approximately 10 days, significantly faster than many international centers.
CAR-T therapy acts as a “living drug,” continuing to work in the body and offering the potential for deep and lasting remission.
All patients are treated under the leadership of Prof. Arnon Nagler, a globally recognized expert in hemato-oncology.
Outstanding Outcomes That Offer Real Hope
These outcomes provide a powerful treatment option and a second chance for patients with limited alternatives.
Why Patients Choose Sheba
• Rapid access to CAR-T therapy – treatment initiation in ~10 days
• Extensive experience – leading CAR-T program in the region
• Dedicated CAR-T units – specialized care with 24/7 monitoring
• Multidisciplinary expertise – hematology, oncology, and immunotherapy teams working together
• Full international support – medical review, travel coordination, and patient assistance
Comprehensive, Personalized Care
Each patient undergoes a full diagnostic evaluation, including advanced imaging, bone marrow biopsy, genetic and molecular testing, and complete medical assessment, ensuring a precise, individualized treatment plan.
Services are available in English, Russian, and Arabic, providing a seamless experience for international patients and their families.
By combining innovative CAR-T technology, in-house cell production, and world-class expertise, Sheba delivers one of the most advanced and accessible CAR-T programs for ALL worldwide, offering patients not just treatment, but a real opportunity for remission and renewed life.
24/7 Bookimed assistance
- Personal medical coordinator
- Medical travel arrangements — booking of air tickets and hotel rooms at special partner prices
- Patient advocacy during medical travel
Program price
special price valid till September 25, 2026
What's NOT included in this package
Doctor
Dr. Arnon Nagler is a hematologist at Sheba Medical Center in Israel. He is a professor at Tel Aviv University and a renowned transplant expert. Dr. Nagler founded Israel’s first public cord blood bank. He also performed the first cord blood transplantations in the country. He completed postdoctoral training at Stanford University and is board-certified in hematology.
- Pioneered reduced–intensity allogeneic transplant protocols for blood cancers.
- Served as Chair of the Acute Leukemia Working Party for the EBMT.
- Published over 400 articles in leading journals like Blood and Leukemia.
- Works at Sheba Medical Center, ranked 7th worldwide by Newsweek in 2026.
How are we doing?
About the clinic
Sheba Medical Center is the largest hospital in the Middle East and ranked 7th worldwide by Newsweek in 2026. It treats over 2 million patients annually and is a global leader in CAR-T and TIL immunotherapies. Core specialties include oncology, immunotherapy, precision medicine, and cardiology.
- JCI and ISO accredited with eight consecutive years in the Newsweek global Top 10.
- In-house CAR-T manufacturing through its GMP-certified Advanced Biotherapy Center (ABC).
- Over 200 Sheba doctors are listed among Forbes' Top Doctors.
- One of the few centers worldwide developing CAR-T therapies for severe autoimmune diseases.
- Campus includes six major hospitals, among them the Leviev Heart Center and Edmond and Lily Safra Children's Hospital.
Payment & Rewards
You don’t pay for our services
You make your payment directly at the clinic or to their official bank account.
Some clinics may require a deposit as a part of their policy.
Spread out your payments with installment options.
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