CAR-T Therapy for Multiple Myeloma at Sheba Medical Center at JCI accreditated and Top-10 Hospitals 2025 by Newsweek Sheba Hospital
What's included in this package
Medical Procedures
- CAR T-cell therapy
- 3 meals per day by nutritionist
- 24-hr nurse services
- CT Scan
- Electrocardiogram (ECG)
- Consultation with a doctor
- Blood tests
- Follow-up examination
- Ultrasound
- Biochemistry blood test
- PET/CT
- Consultation with an oncologist
- Consultation with a hematologist
- Consultation with an immunologist
- Сonsultation with an oncohematologist
- Biopsy
- Complete blood count with cancer markers and a proteinogram
- CT angiography
Duration
- 21 days in the hospital
Accommodation
Hospitalization
Transport
Transfer airport-clinic-airport
Additional information
CAR-T Therapy for Multiple Myeloma at Sheba Medical Center
For patients diagnosed with Multiple Myeloma, especially those with relapsed or treatment-resistant disease, access to advanced therapies can significantly change outcomes.
Sheba Medical Center, one of the world’s leading hospitals, offers state-of-the-art CAR-T cell therapy, providing new hope when standard treatments are no longer effective.
Sheba combines innovative immunotherapy, extensive clinical experience, and rapid access to treatment to deliver highly personalized care for complex myeloma cases.
A Faster Path to Advanced Treatment
At Sheba, the entire CAR-T process is performed on-site, ensuring speed, precision, and optimal cell quality what is a key advantage for patients requiring timely intervention.
• Apheresis – collection of the patient’s T-cells
• Cell Engineering – genetic modification at Sheba’s Advanced Biotherapy Center
• Infusion – reinfusion of modified cells designed to recognize and destroy myeloma cells
By avoiding external laboratories, treatment can begin in approximately 10 days, significantly reducing waiting time compared to many international centers.
CAR-T therapy acts as a “living therapy,” continuing to function within the body and offering the potential for deep and durable remission.
All patients are treated under the leadership of Prof. Arnon Nagler, a globally recognized expert in hemato-oncology.
A Powerful Option for Advanced Myeloma
Multiple Myeloma often requires multiple lines of therapy over time. At Sheba, hematologists, oncologists, and immunotherapy specialists work together to develop a personalized treatment strategy, especially for patients who have exhausted conventional options.
CAR-T therapy has shown promising and durable responses in advanced myeloma, offering a new therapeutic pathway where alternatives may be limited.
Why Patients Choose Sheba
• Rapid access to CAR-T therapy – treatment initiation in ~10 days
• Extensive experience – one of the leading CAR-T programs in the region
• Dedicated CAR-T units – with 24/7 expert monitoring
• Multidisciplinary expertise – integrated care across specialties
• Full international support – medical review, travel coordination, and patient assistance
Comprehensive, Personalized Care
Each patient undergoes a complete diagnostic evaluation, including advanced imaging, bone marrow biopsy, genetic and molecular testing, and full medical assessment, ensuring a precise, individualized treatment plan.
Services are provided in English, Russian, and Arabic, ensuring a smooth and supportive experience for international patients.
A Leading Center for Advanced Myeloma Treatment
By combining innovative CAR-T technology, in-house cell production, and world-class expertise, Sheba delivers one of the most advanced and accessible CAR-T programs for Multiple Myeloma worldwide offering patients a real opportunity for long-term disease control and improved quality of life.
24/7 Bookimed assistance
- Personal medical coordinator
- Medical travel arrangements — booking of air tickets and hotel rooms at special partner prices
- Patient advocacy during medical travel
Program price
What's NOT included in this package
Doctor
Dr. Arnon Nagler is an internationally recognized hematologist and bone marrow transplant expert. He is a Professor of Medicine at Tel Aviv University. He is Director Emeritus of Hematology & Bone Marrow Transplantation and the Cord Blood Bank at Sheba Medical Center. He earned his M.D. from the Hebrew University–Hadassah and an M.Sc. in hematopoiesis from Tel Aviv University. He completed postdoctoral training at Stanford. He is board certified in internal medicine and hematology.
He has more than 35 years of experience. He pioneered reduced‑intensity allogeneic transplant protocols for malignant and non‑malignant diseases. He founded Israel’s first public cord blood bank. He performed the country’s first cord blood transplants.
He has held international leadership roles. He served as Chair and Co‑Chair of the ALWP of the EBMT. He was a vice‑chair and long‑term member of EBMT committees. He served on the board of NetCord/EuroCord and as treasurer. He is a frequent invited speaker. He has published widely in journals such as Blood and Leukemia. He has led major clinical trials as a principal investigator and held editorial roles. He has received multiple awards for innovation and clinical excellence.
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About the clinic
Sheba Medical Center is the largest hospital in the Middle East and one of the world’s leading medical institutions, consistently ranked among the global Top 10. Recognized by Newsweek and Statista for eight consecutive years, it ranked 7th worldwide in 2026. The hospital delivers comprehensive multidisciplinary care across all major specialties, including oncology, hematology, cardiology, neurology, and advanced surgery, treating over 2 million patients annually, including international cases. With more than 200 physicians listed among Forbes' Top Doctors, Sheba is a global leader in CAR-T and TIL immunotherapies, precision medicine, and minimally invasive surgery, making it a trusted destination for complex and advanced treatment.
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