Bone marrow transplant procedure is aimed to save patient lives with such severe malfunctions of blood or immune systems. This intervention is not available in every country. But when it is, the success rate may be higher or lower, depending on whether local clinics have enough experience to perform a procedure. So, many patients — both children and adults — are forced to look for the most effective options worldwide. 

Keep reading the article how much a bone marrow transplant costs globally, what factors affect the price, where you can get a procedure cheaper without outcome worsening, and even book a proper clinic for a BMT procedure.

What Is a Bone Marrow Transplant?

A bone marrow transplant (also referred to as BMT, or stem cell transplant, hematopoietic cell transplantation) is a procedure to replace damaged bone marrow with healthy stem cells. BMT is typically indicated when your own stops or cannot produce a required number of blood cells.

There are 3 types of bone marrow transplants:

  • autologous — a person receives cells taken from own blood; this type is used mainly in patients with leukemia and leukosis if they haven’t affected the bone marrow itself. The transplant is aimed at reviving the body's ability to produce healthy blood cells after chemo- or radiotherapy.
  • allogeneic from a related donor — BMT with the use of bone marrow from a relative donor.
  • allogeneic from an unrelated donor — a patient receives bone marrow from the matched donor through the Bank of Donors. A special blood test can accurately determine the compatibility of a donor and a recipient for transplantation.

Why Is Bone Marrow Transplant Performed?

A bone marrow transplant can be used to:

  • replace a malfunctioned bone marrow with healthy stem cells (typically in case of leukemia, anemia)
  • Replace a bone marrow and enhance it for a normal functioning after high dose of radiation- and chemotherapy.
  • Restore a bone marrow affected as a result of some genetic diseases progress (for instance, Hurler's syndrome and adrenoleukodystrophy (ALD).

Bone marrow procedure overview

Diseases and Conditions Treated by BMT

The bone marrow transplant surgery is performed to treat people of all ages suffering from hematological and autoimmune diseases, in particular, leukemia, thalassemia, lymphoma, anemia, myeloma, and immune deficiency.

Bone Marrow Transplant: Procedure Overview

Each patient within bone marrow procedure should go through such stages:

  • Pre-op medical evaluation
  • Collecting stem cells (own or donor ones)
  • Chemo or/and radiation therapy cycles
  • Procedure itself
  • Post-op follow-up.

Let's consider these conditions more detailed below:

Pre-op medical evaluation

Before a BMT procedure, a patient undergoes medical tests to evaluate general health conditions and some specific indicators. Then a nurse places a catheter in the vein to inject required medications and solutions. 

The price for bone marrow transplants usually includes expenses for pre-op BMT preparation.

Stem cell collection 

The next important step is to collect stem cells for infusion. If we speak about autologous BMT, you will receive special medications to stimulate your own stem cells production for further collection. 

If a patient expects for allogeneic BMT and a donor is found, then doctors gather donor cells.

Chemo or/and radiation therapy cycles

Before bone marrow transplant infusion, a patient undergoes chemo- or radiotherapy to destroy cancer cells if you have cancer diagnosis, suppress the immune system for better adopting new cells. 

Procedure itself

A BMT procedure is absolutely painless, and is similar to the blood transfusion process. A patient stays awake and conscious, no anesthetic solution is needed. New bone marrow bodies are administered through a catheter in the vein.

Post-op follow-up

Once new bone marrow cells reach your body, they travel through the bloodstream, reach a bone marrow and start multiplying. In several weeks, healthy stem cells will reach a required level. 

How Much Does Bone Marrow Cost Worldwide?

The price of a bone marrow transplant differs across the world. Below you can get familiar with the outline demonstrating the BMT price range globally.

Country

Price

Turkey

from $20,000

India

from $15,000

Thailand

from $137,000

Germany

from $197,000

South Korea

from $115,000

Spain

from $72,000

Israel

from $190,000

Great Britain

from $170,000

USA

from $400,000

The price for a stem cell transplant pointed in the table is initial: it may reach, depending on a transplant type, patient health condition, and further toleration of transplant cells.

Autologous vs. Allogeneic Bone Marrow Transplant Types: Price Overview

There are 2 main types of bone marrow transplant known — autologous and allogeneic ones. The cost of autologous BMT is lower compared to allogeneic as far as own patient cells are taken. 

In case of an allogeneic BMT, the significant part of expenses is wasted on analysis to detect the best donor match, so an average cost can be increased by twice. You can compare approximate prices for these 2 type of BMT procedure in the table below:

Country

Autologous BMT price

Allogeneic BMT price

Turkey

from $30,000

from $40,000

India

from $11,000

from $21,000

Germany

$164,000

$275,000

Spain

from $72,000

from $127,000

Thailand

from $137,000

on request

South Korea

from $115,000

on request

Great Britain

from $170,000

from $210,000

USA

from $400,000

from $550,000

TOP Bone Marrow Transplant Centers List

We have collected bone marrow transplant centers located in different countries and estimated high by Bookimed patients:

Turkey

Anadolu Medical Center
Turkey, Istanbul
92% patients recommend

Anadolu Medical Center is a multidisciplinary medical facility located in Istanbul, Turkey. It is affiliated with the Johns Hopkins Hospital in the USA and recognized as one of the top 10 hospitals in the world by the Medical Travel Quality Alliance (MTQUA). Anadolu provides American treatment standards at an affordable cost and offers a wide range of services, including oncology, hematology, urology, neurosurgery, women's health, IVF, and check-ups. Doctor Zafer Gülbaş, Prof. MD, is the founder of Anadolu's Bone Marrow Transplantation Center and is one of the top lymphoma specialists in Turkey, with over 1,500 bone marrow transplants performed to date. The clinic provides a "all inclusive" leukemia treatment program which includes diagnosis, chemotherapy, and the Bone marrow transplantation in Turkey. Anadolu Medical Center offers language assistance, transfer service from the airport to the hotel and back, as well as booking a hotel conveniently located 10-15 minutes away. Patients from the US, UK, Romania, Bulgaria, and Azerbaijan have praised Anadolu Medical Center for its professionalism, cleanliness, attention to detail, and skilled and experienced medical staff.

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Hospital certificates and accreditation of quality

International Organization for Standardization certificate for Anadolu Medical Center Joint Commission International  certificate for Anadolu Medical Center European Society for Medical Oncology certificate for Anadolu Medical Center Organisation of European Cancer Institutes Certificate certificate for Anadolu Medical Center  Johns Hopkins Medicine certificate for Anadolu Medical Center Patient Choice for Basic Check-up certificate for Anadolu Medical Center Patient choice in Oncology & Hematology Oncology certificate for Anadolu Medical Center International Accreditation System for Interventional Oncology Services (IASIOS) certificate for Anadolu Medical Center  Planetree's Gold Certificate certificate for Anadolu Medical Center

Latest review

Verified review.
Everything in the clinic is at the highest level, now we are undergoing examination and treatment, using modern equipment, doctors found another tumor that was not seen in Ukraine, the pro doctors inspire 100% confidence. Interpreter Svetlana constantly supports and knows how to calm her down and she is a very pleasant woman. If you want to recover and live long, come to Anadolu! Many thanks to the bookimed team for organizing, our coordinator Alexey is just super. Thanks a lot, everyone!
— Евгений
Ukraine, Jul 7, 2023
Jul 7, 2023 • Verified review.
Consultation with an oncologist:  Before and After Photos. Explore patients' results Consultation with an oncologist:  Before and After Photos. Explore patients' results

Medipol Mega University Hospital
Turkey, Istanbul
87% patients recommend
  • The BMT is performed for children and adults at Medipol.
  • 500,000 patients choose Medipol for treatment annually. A significant number of them prefer Medipol to have the best bone marrow transplant.
  • Medipol is 1 out of 4 medical centers in Turkey equipped with Pyxis Medication Management System that controls the medicines taking. It provides a patient with a right drug and dose in an appropriate time. This system excludes any error in medicines taking.
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Hospital certificates and accreditation of quality

Joint Commission International  certificate for Medipol Mega University Hospital Patient choice in Pediatric Oncology & Hematology Oncology certificate for Medipol Mega University Hospital

Latest review

Verified review.
Hello! I thank the bookimed team for getting us to the clinic in Medipol Turkey. I was very confused and did not even know how to find a clinic! I accidentally looked at this clinic on YouTube and decided to write to bookimed. You just have no idea how scared I was thinking if I was doing the right thing! It turns out to be very correct. I got good doctors. I am satisfied. God forbid that my son recovers and that no one ever gets sick. Many thanks to Marina, she is always my motivator at any time, I can write to her, she will gladly answer and explain everything to me. May Allah grant you all long life and health! Come visit us in Tashkent, I love you all! The most important thing in life is health, I completely changed my priorities, because when you understand that you can’t do anything, you start just asking Allah.
— Гульноза
Uzbekistan, Jul 27, 2023
Jul 27, 2023 • Verified review.

Memorial Şişli Hospital
Turkey, Istanbul
89% patients recommend

Memorial Şişli Hospital in Istanbul is the largest multidisciplinary medical center in Istanbul. It is the 1st hospital in Turkeу and the 21st in the world accredited by Joint Commission International (JCI) for the high quality of treatment.

Memorial Şişli specialties are the following: oncology, bone marrow transplant, in vitro fertilization (IVF), neurosurgery, and organ transplant. The success rate of organ transplant at Memorial is 90%.

Patients from 92 countries choose Memorial Şişli for treatment annually.

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Hospital certificates and accreditation of quality

International Organization for Standardization certificate for Memorial Şişli Hospital Joint Commission International  certificate for Memorial Şişli Hospital

Latest review

Verified review.
I recently had strabismus surgery at Memorial Şişli Hospital in Turkey and I am extremely satisfied with my experience. The hospital's facilities were top-notch and the staff was friendly and attentive. What stood out the most was the expertise and care provided by the doctor. The surgery went smoothly, and the post-operative care was thorough. I highly recommend Memorial Şişli Hospital for anyone seeking medical treatment.
— BoldErdene
Republic of Korea, Aug 27, 2023
Aug 27, 2023 • Verified review.

Emsey Hospital
Turkey, Istanbul
91% patients recommend

Emsey Hospital is a multi-specialty private medical center located in Turkey, providing healthcare services to patients from all around the world since 2012. It has ISO and JCI accreditation, and offers treatments in general medicine, surgical medicine, and internal medicine. The hospital also has an Advanced Spine Surgery Center and a Bone Marrow Transplantation Unit with 45 beds, making it one of the largest BMT units in Turkey. The clinic has received many positive reviews for its well-tuned system for a comfortable stay, examination, and treatment. Patients are met at the airport and placed in a good hotel with all amenities. The doctors are experienced and highly qualified, and the language barrier is managed with interpreters. The hospital offers transfer services from airport-hotel-clinic-airport. The Bone Marrow Transplantation procedure is performed by Doctor Serdar Bedii Omay, who has international articles and publishings in the field of Hematology and Bone Marrow Transplantation. For more information, visit Emsey Hospital for the Bone Marrow Transplantation procedure in Turkey.

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Hospital certificates and accreditation of quality

Joint Commission International  certificate for Emsey Hospital

Latest review

Verified review.
I liked everything very much, we were met at the airport, we were put up in a luxury hotel, it is located next to the hospital, it is very convenient, the next day we met at the hospital with an interpreter, we went around, we waited for all the tests and on the same day the operation was performed, the care was super, they were discharged on the third day. Everything was super, I recommend this to everyone clinic 🥰
— Юлия
Poland, Sep 21, 2023
Sep 21, 2023 • Verified review.

Germany

Helios Hospital Berlin Buch
Germany, Berlin
92% patients recommend

Helios Hospital Berlin Buch is the largest and modern hospital in the capital of Germany. It is one of the top-ranked hospitals in 2018 according to the Focus magazine. It provides treatments of oncology and surgical oncology, orthopedics, neurosurgery and obesity. The hospital is highly recommended by 94% of patients.

The clinic offers Bone marrow transplantation in Germany, which is provided by the experienced doctor Bertram Glass. Prof. Glass is an expert in hematology, internal oncology and stem cell transplant, who heads the Hematology Department at Helios Berlin-Buch. He is a lecturer at Asklepios Medical School and professor at the University Medical Center Gottingen.

Patients who have visited the hospital appreciate the staff, the quality of the medical services and the comfortable accommodation which corresponds the level of a 5* hotel. Patients also express their gratitude to Bookimed employees for organizing their trips.

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Hospital certificates and accreditation of quality

International Organization for Standardization certificate for Helios Hospital Berlin Buch TOP German hospital according to 2019 Focus ranking certificate for Helios Hospital Berlin Buch World's Best Hospitals 2021 by Newsweek certificate for Helios Hospital Berlin Buch

Latest review

Verified review.
The clinic and the professor are just BEAUTIFUL !!! It is a pity that in our countries not everyone can afford treatment there. Sorry, but this is sincere.
— Виктор
Ukraine, Dec 18, 2021
Dec 18, 2021 • Verified review.

Thailand

Bumrungrad International Hospital
Thailand, Bangkok
90% patients recommend

Bumrungrad International Hospital is a global medical facility in Bangkok, Thailand that specializes in oncology, ophthalmology, orthopedics, neurosciences, heart surgery, check-ups, etc. Over 1 million patients choose Bumrungrad annually. 50% of them are international ones from over 190 countries.

The hospital is one of the largest private centers in Southeast Asia and one of the most significant world’s outpatient clinics. Bumrungrad International is recognized as TOP-10 best hospitals and TOP-30 most technologically advanced clinics in the world.

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Hospital certificates and accreditation of quality

International Organization for Standardization certificate for Bumrungrad International Hospital Joint Commission International  certificate for Bumrungrad International Hospital Global Healthcare Accreditation Program certificate for Bumrungrad International Hospital World's Best Hospitals 2020 by Newsweek certificate for Bumrungrad International Hospital World's Best Hospitals 2021 by Newsweek certificate for Bumrungrad International Hospital World's Best Smart Hospitals 2021 by Newsweek certificate for Bumrungrad International Hospital World's Best Hospitals 2022 by Newsweek certificate for Bumrungrad International Hospital World's Best Smart Hospitals 2023 by Newsweek certificate for Bumrungrad International Hospital

Latest review

Verified review.
Bookimed had suggested me the best doctors for my kids and myself. As I preferred to have my booking in the Bumrungrad hospital, they exactly understood my requirements and provided with great help. For anyone who doesn’t have any experience also will get proper guidance from bookimed. Thanks a lot.
— Prema
Bangladesh, Sep 10, 2023
Sep 10, 2023 • Verified review.
Consultation with an endocrinologist:  Before and After Photos. Explore patients' results Consultation with an endocrinologist:  Before and After Photos. Explore patients' results

Italy

San Donato Hospital
Italy, Milan
87% patients recommend

Ospedale San Raffaele (San Raffaele Research Hospital) in Milan is one of the largest research hospitals in Europe, offering ad hoc methods for rare immune system and genetic diseases treatment. The hospital is particularly strong in oncology, oncohematology, neurosurgery, neurology, cardiovascular surgery, urology, and gynecology, performing over 52,000 operations annually.

The hospital offers Bone Marrow Transplantation in Italy, with the world's first stem cell therapy for patients with severe combined immune deficiency disorder (ADA-SCID).

The hospital has received positive reviews from patients, who praised the staff and organization of the hospital. Led by Professor Fabio Ciceri, the Hematology and Bone Marrow Transplantation Unit at San Raffaele Research Hospital and the Blood Transfusion Centre, the hospital is a reliable choice for treatment.

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Hospital certificates and accreditation of quality

Scientific Institute for Research and Healthcare Accrediatation certificate for San Donato Hospital World's Best Hospitals 2021 by Newsweek certificate for San Donato Hospital

Latest review

Verified review.
The Hospital handled my appointment and the paperwork promptly and efficiently. My outpatient contact with the Consultant was very professional. I would not hesitate to recommend Bookimed for enabling to have the required treatment.
— Anonymous
Italy, Jan 22, 2022
Jan 22, 2022 • Verified review.

Israel

Hadassah Medical Center
Israel, Jerusalem
90% patients recommend
  • Hadassah Bone Marrow Transplant Department is the 1st in Israel to receive the accreditation from Joint Accreditation Committee ISCT-EUROPE & EBMT (JACIE). It means that BMT procedure at Hadassah is performed at the same level as in top world bone marrow transplant hospitals.
  • More than 3,500 bone marrow transplant procedures have been performed at Hadassah — 1,200 of them for children.
  • Over 40 years of experience in bone marrow transplantation.
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Hospital certificates and accreditation of quality

Nobel Peace Prize certificate for Hadassah Medical Center World's Best Hospitals 2021 by Newsweek certificate for Hadassah Medical Center World's Best Smart Hospitals 2021 by Newsweek certificate for Hadassah Medical Center

Latest review

Verified review.
Hello! My husband was treated at the University Hospital Hadassah. He has liver cancer. He is extremely impressed with the quality of medical care, the attention of professors Daniel Shuval, Alan Bloom, Ayal Hubert and their colleagues. He is grateful for the care of him. We had the opportunity to choose treatment in 5 leading hospitals in the world. And we are glad that by choosing HADASS we made the best and the right choice. Because this hospital has world-class medical care. But this would not have happened if it had not been for the wonderful organization and work of the specialists from the International Department who have been helping us all the time. With all my heart I thank everyone who helped and continues to help Pavel Kalchev in his fight against cancer. I wish all HADASS specialists health. Health for their families. Ivelina Krustinkova Bulgaria
— Ивелина
Bulgaria, Feb 28, 2020
Feb 28, 2020 • Verified review.

What Do Factors Affect BTM Cost?

As you see, the cost of bone marrow transplant procedure ranges significantly. And literally, a low cost does not mean poor efficacy, and the high one does not guarantee an excellent result. 

Let’s puzzle out why BMT costs range so drastically, and what factors are primary influencers:

Country

The country you are going to have BMT surgery is among top factors that determines the final price of your treatment. The deal is that some countries provide lower price policies for all goods and services, including medical ones. So,medical education and doctors’ fees are lower, too. So, countries with mild price policies are Turkey, India, Poland, Czech Republic, etc. While the USA and the UK, countries with high citizen income, provide medical assistance at a corresponding high level.

BMT type

One more criteria affecting bone marrow transplant cost is its type — autologous or allogeneic ones. For patients, who need allogeneic BMT, doctors will be searching for a donor and wasting time and expenses for matching tests. Plus, it requires efforts and material to collect donor stem cells, transport, and preserve them.

Patient condition

The more severe patient condition is, the longest hospital stay, more medications, and additional therapies are required. Due to this, only your doctor can determine a complete list of medical services needed, with further cost estimation.

What Does BTM Price Contain?

The price is packaged, and it covers:

Please note that this is a preliminary list of the services. It can differ between hospitals and countries. And the price mostly depends on the patient’s necessity in searching for a donor.

What Else Influences the Bone Marrow Price?

The bone marrow transplant cost depends on:

  • The stage of disease
  • Comorbidities and complications if any
  • The pricing policy in the selected country and hospital.

Why Is Bone Marrow Transplant So Expensive?

Type of required BMT

The cost of a bone marrow/stem cell transplant primary depends on the procedure type — autologous (with patient's marrow cells) or allogeneic (with cells, harvested from a donor) with the sequential steps.

In case, a patient requires a donor, a medical team starts a process to find a person with similar genetic markers in the blood for a transplant. It can be a family member or an unrelated donor.

Searching for a donor requires appealing to the donor banks, finding matches and the following testing. Thus, it is a time & money consuming procedure.

The cost of allogeneic transplant from an unrelated donor is twice as expensive as a transplant from a related donor.

It costs almost three times as much as an autologous BMT (in Turkey, for instance).

Patient's age and hospital stay

Transplants are usually more expensive in patients younger than 20 years (considered as pediatric patients) due to more extended in-hospital stay.

For example, pediatric patients have 1.6 times higher average cost of bone marrow transplant and expenses for outpatient care compared with adult recipients. The median total duration of hospitalization was 43 days vs. 30 days according to the Center for International Blood and Marrow Transplant Research (USA).

In general, the hospital stay takes up to 30 days. The preliminary period before the transplant takes 5-10 days. During the period, a patient takes drugs or receive chemotherapy, and/or radiotherapy to destroy unhealthy cells. This time is called a conditioning regimen.

After a transplant, a patient is vulnerable to infections because of the weak immune system. At the time, transplanted stem cells start to grow and develop, and the person’s immune system is recovering. A patient is put into a special ward with air filters to make sure no microbes or infections get into it.

In case of any post-transplant complications, the discharge is also postponed increasing the total cost of stem cell transplantation.

Bone Marrow Transplant Cost with Insurance

For patients, covered by health insurance, the out-of-pocket costs for a bone marrow transplant typically consist of doctor's fee, lab, and prescription drug copays as well as coinsurance of 10-50% for the procedure. Most health insurance plans cover the total cost completely or partly. It includes preliminary testing, the collection, and delivery of stem cells, the procedure, and post-operative recovery costs. The prices can vary depending on a region and hospital.

Personal expenses associated with bone marrow transplants, such as food and lodging expenses, incurred, when a patient and their family moves to be closer to a transplant center, are not covered by insurance.

Get a BMT cost estimate

FAQ

Is bone marrow transplant successful?

75 to 91.5% patients reach up 1-year survival rate after the procedure. The result depends on the patient's age, and condition, the medical team's professionalism, donor-recipient matching. The outcome is much better the closer donor's profile is to the recipient's needs.

People usually gain excess fat because they do not follow doctor's recommendations and ignore a healthy lifestyle.

What is bone marrow transplant side effects?

The risk of side effects from the infusion is minimal. Fever, low blood pressure, chest pain, cough are among short-term side effects after the procedure. During the rehab after stem cells transplants, a patient can face infections, organ dysfunction, infertility, depression, and some others.

What is bone marrow transplant side effects?

The risk of side effects from the infusion is minimal. Fever, low blood pressure, chest pain, cough are among short-term side effects after the procedure. During the rehab after stem cells transplants, a patient can face infections, organ dysfunction, infertility, depression, and some others.

Who can give bone marrow transplant?

Anyone can be a donor if a person is healthy and has a desire. A person can donate blood cells to a relative or a stranger. In this case, it’s necessary to contact the nearest donor register and find out the details. Each bank has its criteria and procedure for donating. Once you register, your blood samples are compared with those who are seeking treatment. If you match, you'll be asked for a donation. According to the Be The Match Foundation, a chance to become a donor is 1 in 430.

Is bone marrow transplant safe for the donor?

The procedure is safe but can go along with some side effects as a headache, pain in the back or hip, fatigue. Still one should remember that no medical procedure is risk-free.

How does bone marrow transplant work for the donor?

  • There are 2 ways of donating: marrow stem cells or peripheral blood cells (PBSCs). The patient’s treating doctor chooses the way.
    If PBSCs donation: 91% of donors have 1 session. A person is connected to a blood cell separator device via tubes in both arms. The device collects cells from your arm, picks some platelets and white blood cells into a special bag. Afterward, it returns plasma and red blood cells to your body via the other arm.
    If marrow donation: it's a surgical procedure under general anesthesia. A doctor collects marrow from both sides of the donor’s pelvic bone via small incisions. Most donors return home the same day or the next day after the donation.

Can bone marrow transplant change blood type?

Yes, after the allogeneic transplant a recipient’s blood type is changed into the donor's. Healthy blood cells with their own set of antibodies and antigens replace the damaged cells with their sets. The complete replacement takes 4-6 weeks.

Can bone marrow transplant change DNA?

Yes, it can. A person has the allogeneic transplant from an unrelated donor. As the result, donor's genome gets to the recipient's and a person has 2 sets of DNA, not one as usual. This phenomenon is called chimerism.

Takeaways

A bone marrow transplant is the main hope for people with blood cancers and some disorders affected bone marrow. The procedure is associated with physical difficulties, prolonged hospitalization and is quite a pricey one. The hospital should be chosen according to the experience of a transplant team and its heading doctor, hospital’s equipment and services provided. The BMT cost depends on the range of factors, including bone marrow transplant type, the patient’s condition and pricing policy in the country.

The most affordable option can be find in Indian and Turkish hospitals — the prices are explained by the economic growth level in these countries. The most affordable option in Europe is considered Italian hospital while Germany offers the highest prices.

In case you would like to have an appointment in the hospital or need assistance in selecting the right one, submit a request and we will do our best to take care of your medical travel.