A spinal cord injury can change a life in an instant, often leading to permanent paralysis, chronic pain, and a loss of independence. With no definitive cure, patients are left navigating a complex and frustrating road to recovery.
New advances in stem cell therapy are changing the outlook, offering a way to repair nerve damage and restore movement. In this article, weâll cover the top destinations for stem cell therapy, how the treatment works, and what to look for when choosing a clinic.
Top Countries and Costs
Table of Contents
- Best Destinations Offering Stem Cell Treatment for Spinal Cord Injury
- Choosing a Stem Cell Treatment Center
- Cost of Stem Cell Treatment for Spinal Cord Injury
- Spinal Cord Injuries and Stem Cell Therapy: How It Works
Best Destinations Offering Stem Cell Treatment for Spinal Cord Injury
If youâre considering stem cell therapy for traumatic spinal cord injury, location makes a difference. Some countries stand out for their convenient legislation, progressive treatments, experienced specialists, and affordable care.
According to Bookimedâs research, Mexico, Turkey, and Colombia are top destinations for stem cell therapy. Each offers unique advantages, from support on the state level to leading clinics. Letâs take a closer look.
Country | Top clinics | Highlights | Cost Range |
|---|---|---|---|
Cellular Hope Institute | Mexico allows a broader application of stem cell therapies regulated by COFEPRIS. Itâs a popular destination for U.S. residents, including high-profile patients. | $5,000 - $15,000 | |
Turkey is a significant hub for regenerative medicine, supported by regulations from the Ministry of Health and the Turkish Academy of Sciences. Turkish clinics are accredited by international bodies and comply with GMP standards. | $8,000 - $15,000 | ||
INVIMA, Colombiaâs FDA equivalent, strictly regulates stem cell treatments. It is growing in popularity among international patients, including professional athletes. | $7,000 - $11,000 |
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Stem cell therapy for spinal cord injury in Mexico
đ” Average cost: $5,000 - $15,000.
Mexico is a go-to destination for Americans seeking stem cell therapy. This is primarily because, in the US, the FDA hasnât yet approved stem cell therapy for spinal cord injury beyond a few clinical trials. On the other hand, Mexicoâs health authority, COFEPRIS, allows and regulates the broader application of stem cells, including for spinal cord injuries. In Mexico, US residents can get legal, advanced care without traveling too far from home.
đ Best stem cell therapy clinics in Mexico
Guided by the Ranking Policy, Bookimed has analyzed over 150 stem cell clinics worldwide to find the best options for stem cell therapy. These Mexican clinics represent the optimal balance of pertinent treatments, accreditations, popularity, and patient satisfaction:
đ„ Located in Cancun, Cellular Hope Institute has 12 years of experience in regenerative medicine. It has treated high-profile patients, including Mike Tyson and Cristiano Ronaldo.
Stem cell therapy at Immunotherapy Regenerative Medicine in Puerto Vallarta, Mexico may cost around $3,000 for shoulder injections. The clinic specializes in regenerative medicine with 20+ years of experience, led by Dr. Ernesto Romero who has performed over 1,100 stem cell treatments.
About the Treatment
Mesenchymal stem cell therapy uses 50 million to 1 billion cells depending on the condition. The cells are delivered through local injections, IV infusions, or spinal fluid applications. Treatment duration ranges from 1 to 10 days.
What's Included
- Stem cell injections (50-100 million cells per site)
- Medical assessment and consultation
- Airport transfers
- Personalized treatment plan
- Interventional injections (joints or spine)
Doctor's Expertise
Dr. Ernesto Romero has 22 years of experience in regenerative medicine. He founded the biotechnology institute Bioplenum and researches stem cell protocols for ALS, diabetes, and arthritis. His clinic developed the MISID activation technique to enhance stem cell effectiveness.
Conditions Treated
The therapy helps with neurological diseases like Parkinson's and Alzheimer's, plus joint degeneration and dental bone loss. Most patients resume normal activities within 24 hours after this outpatient procedure.
For those seeking alternative regenerative treatments, the clinic offers various programs starting from $3,000. Contact them to discuss personalized options.
Hospital certificates and accreditation of quality
Latest review
đ„ Based in Puerto Vallarta, Immunotherapy Regenerative Medicine is a clinic pioneering regenerative medicine for over 20 years. Its team of biologists and biophysicists develops advanced protocols with mesenchymal stem cells.
Stem cell therapy at Juventa Regenerative Medicine in Playa del Carmen, Mexico may cost around $6,000. The clinic specializes in regenerative treatments using mesenchymal stem cells and exosomes, with Dr. Isabella Bernaschina leading the procedures as an RCG-certified specialist.
Treatment Options
The clinic offers customized stem cell packages:
- 100 million MSC + 20 billion exosomes ($6,000) for polyneuropathy/psoriasis
- 200 million MSC + 10 billion exosomes ($8,500) for cardiovascular regeneration
- 150 million MSC + 20 billion exosomes + 70 million NK ($7,900) for HIV support
What's Included
Each package contains:
- Stem cell IV therapy (100-200 million MSC)
- Exosome IV therapy (10-20 billion)
- Placenta implant
- NAD+ IV drip
- 3-4 nights accommodation
- VIP airport transfers
Procedure Details
The intravenous therapy takes 3-4 nights with physician consultation included. Patients typically stay 4-5 days in Mexico. The treatment aims to improve energy levels within days post-procedure.
Dr. Bernaschina holds certifications in stem cell therapies and belongs to AMPTI. The clinic treats over 500 international patients yearly with VIP services throughout their stay.
Interested patients can inquire about current package availability and payment options.
Latest review
| Stem Cell Therapy | $5000 - $6500 |
đ„ Medical Center Juventa is situated in Playa del Carmen and is led by Dr. Isabella Bernaschina, an expert in regenerative medicine.
đ„ Learn about the intricacies of stem cell therapy in our exclusive interview with Dr. Bernaschina:
Stem cell therapy at Giostar Stem Cell Therapy | Cancun Clinic in CancĂșn, Mexico may cost around $6,900 to $18,968 USD depending on the protocol. The clinic specializes in regenerative treatments using umbilical cord-derived stem cells, with 98% patient satisfaction and personalized treatment plans under Dr. Evelyn GarcĂa's guidance.
About the Treatment
The clinic uses umbilical cord-derived mesenchymal stem cells (UC-MSCs) for various conditions. Procedures typically take 1-2 sessions. Patients receive between 70 million to 105 million stem cells based on their needs.
Treatment Protocols
- Facial rejuvenation: 70 million cells + 2 billion exosomes (~$6,900)
- Orthopedic shoulder repair: 105 million cells + 7 billion exosomes (~$9,879)
- ALS neurodegenerative care: 4 vials UC-MSCs + 8 billion exosomes (~$15,968)
Doctor Profile
Dr. Evelyn GarcĂa leads the clinic with 5 years of specialized experience. She has performed over 900 stem cell treatments. Her training includes a Master's in Regenerative Medicine from Spain's Complutense University of Madrid.
What's Included
Treatment packages typically cover airport transfers, 4-star hotel stays, medical consultations, and follow-up care. Patients usually stay 2-7 days depending on their protocol.
The clinic welcomes international patients with multilingual staff. For exact pricing, patients receive personalized quotes after consultation.
Latest review
đ„ Giostar Stem Cell Therapy Clinic is located in Playa del Carmen and headquartered in San Diego, USA. It combines American innovation with the convenience of treatment in Mexico. This global leader in stem cell therapy offers patients the benefits of U.S.-based research and expertise.
Stem cell therapy for spinal cord injury in Turkey
đ” Average cost: $8,000 - $15,000.
Turkey is a major hub for medical tourism, including regenerative medicine. The Turkish Ministry of Health regulates stem cell treatments. The Turkish Academy of Sciences actively supports research through the TĂBA Stem Cell Work Group. These efforts ensure high standards of care and a collaborative environment that encourages scientific advancements.
đ Best stem cell therapy clinics in Turkey
Stem cell therapy at Liv Hospital Ulus in Istanbul, Turkey may cost around 20,000 EUR for a 15-day program. The treatment includes 2 doses of stem cells and 6 ozone therapy sessions under the care of Prof. Dr. Erdal Karaöz, a pioneer in regenerative medicine.
Treatment Program
The therapy uses mesenchymal stem cells from umbilical cord tissue. These cells meet GMP quality standards. The treatment involves three delivery methods:
- Intrathecal injection into the spinal canal
- Intravenous infusion into the bloodstream
- Intramuscular injection for localized effect
What's Included
The 20,000 EUR package covers:
- 2 doses of allogeneic mesenchymal stem cells
- 6 sessions of rectal ozone therapy
- Mesenchymal stem cell-derived exosomes
- Interpreter services during treatment
Medical Team
Prof. Dr. Erdal Karaöz leads the treatment program. As a specialist in regenerative medicine and genetics, he focuses on cellular therapies. The hospital holds JCI accreditation, ensuring international care standards.
Treatment Plan
Patients typically stay for 15 consecutive days. Alternative schedules are available. Before therapy, patients stop blood thinners and complete health screenings. Follow-up assessments determine if additional doses are needed.
The clinic provides free transfers in Istanbul. Interested patients can get more details about individual treatment plans.
Hospital certificates and accreditation of quality
Latest review
| Stem Cell Therapy | $6750 - $7250 |
đ„ Liv Hospital specializes in orthopedic stem cell treatments. It was the first in Turkey to comply with Good Manufacturing Practice (GMP) standards. It is certified by the Turkish Ministry of Health for cultivating and administering stem cells.
Stem cell therapy at Medipol Mega University Hospital in Istanbul, Turkey may cost around $65,000 for related donor transplants. The hospital is the first JCI-accredited academic medical center in Turkey, offering specialized inpatient care for 60-90 days. Prof. LeylagĂŒl Kaynar, Professor of Hematology, leads the stem cell transplantation program with expertise in allogeneic procedures.
Treatment Options
Patients can choose between two main options:
- Related donor transplantation for around $65,000
- Unrelated donor transplantation with international search for about $105,000
What's Included
The treatment package covers:
- Stem cell transplantation procedure
- Donor search services
- Pre-treatment diagnostic tests
- Hospital transfers and VIP assistance
- Translation services
Hospital Stay
Patients typically stay 60-90 days in the hospital. The 810-bed facility includes 127 ICU beds for specialized care. Pretreatment involves genetic analysis and bone marrow examination.
Additional Information
The hospital runs a complete transplant unit for adults and children. It collaborates with REMER center for stem cell research. Treatment uses peripheral blood or bone marrow stem cells collected through apheresis or surgical harvest.
If you're considering stem cell treatment abroad, Medipol Mega offers comprehensive international patient services.
Hospital certificates and accreditation of quality
Latest review
| Stem Cell Therapy | $5000 - $10000 |
đ„ Located in Istanbul, Medipol Medical Center serves over 1,200 patients daily. Stem cell treatments are overseen by Dr. Ahmet Murat BĂŒlbĂŒl, an orthopedic surgeon with over 22 years of experience.
Stem cell therapy for spinal cord injury in Colombia
đ” Average cost: $7,000 - $11,000.
Colombia is gaining recognition for a wide range of available stem cell treatments, including for spinal cord injury. Stem cell therapy is approved and strictly regulated by INVIMA, the countryâs FDA equivalent. Colombia has especially gained traction as a destination for sports injury treatment with stem cells. It is frequented by professional MMA fighters and wrestlers.
đ„ Located in MedellĂn, Reju Medical Clinic offers stem cell treatments for various medical conditions, from orthopedic to autoimmune diseases. The clinic employs professionals with over 15 years of experience. Itâs in demand among patients from the USA, Canada, and Australia. Reju has additional branches in Mexico, Turkey, Thailand, Azerbaijan, and Belgium. It offers global expertise and a strong care network.
Choosing a Stem Cell Treatment Center
For patients with spinal cord injury, finding the right stem cell therapy center can make all the difference. This treatment is still in its early stages, so choosing a reliable clinic with appropriate expertise is crucial. Here are some tips to guide your decision:
1ïžâŁ Check regulatory approvalÂ
The clinic should be certified by the countryâs health authority (like COFEPRIS in Mexico or INVIMA in Colombia). Their stamp of approval means the treatments meet safety and quality standards and lowers the risk of ineffective or unsafe therapies.
2ïžâŁ Verify experience and credentials
Look for clinics with a strong track record in spinal cord injury treatment. Specialists experienced both in regenerative therapies and orthopedics are more likely to understand the complexities of these injuries.
3ïžâŁ Ask about the source of stem cells
Different types of stem cells are used to treat spinal cord injuries, each with its benefits. Confirm that the clinic uses ethically sourced, high-quality cells suited for nerve regeneration.
4ïžâŁ Look for transparent treatment protocols
A reputable clinic will provide detailed information about how they process and administer stem cells. Be wary of places that make vague promises without clear explanationsâthey might not be trustworthy.
5ïžâŁ Pick a clinic with a multidisciplinary team
Spinal cord injury treatments require many types of experts, including neurologists, regenerative medicine specialists, and rehabilitation therapists. A clinic with a diverse team can provide a more comprehensive and effective treatment plan.
6ïžâŁ Look at what patients say
Look for detailed reviews from patients with spinal cord injuries. Real experiences can give insight into a clinicâs success rate, patient care, and the quality of their services.
7ïžâŁ Ask about rehabilitation support
Effective treatment doesnât end with the procedure. For spinal injury patients, physical rehabilitation is key. Check if the clinic provides integrated rehab support to help you regain strength and mobility.
8ïžâŁ Check clinic affiliations
Clinics that work with research institutions or well-known hospitals are often more reliable. These connections help them stay up-to-date with the latest findings in regenerative medicine. This is especially relevant for complex conditions like spinal cord injuries.
9ïžâŁ Consider travel and accessibility
If youâre traveling abroad, consider the location and whatâs included in the package. Some clinics offer comprehensive services that cover travel, accommodation, and transfers. Such packages make it easier for international patients with spinal cord injury to focus on their treatment.
đ Get a clear cost breakdown
Stem cell treatment for spinal cord injuries can be costly. Ask the doctor to give you a detailed cost breakdown for all parts of the treatment. This will help avoid surprise charges and give you a clear idea of what youâre paying for.
đ If you're unsure where to start, leave a request on Bookimed. Your personal medical coordinator will discuss your needs, preferences, and budget. They will help you choose the best option for spinal cord injury from our network of over 150 stem cell therapy providers. This way, you can find a trusted clinic thatâs right for your condition without unnecessary hassle.
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Cost of Stem Cell Treatment for Spinal Cord Injury
Since traumatic spinal cord injury is a complex and severe condition, treatment tends to be on the higher end of the price range. On average, stem cell therapy can cost anywhere from $20,000 to $100,000 per treatment session in Europe. Patients may need multiple sessions, which will further increase the total expense.
In Mexico, Turkey, and Colombia, stem cell treatment costs are typically 50-70% lower than in Europe. This significant price difference is due to lower operational costs, wider stem cell therapy approval, favorable exchange rates, and government support for medical tourism. Accredited clinics in these countries follow the regulations of national health authorities while keeping prices more affordable for international patients.
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đ€ Does insurance cover stem cell therapy?
Insurance doesnât usually cover stem cell therapy for spinal cord injuries. This is because these treatments are still considered experimental and, in the case of the USA, have not received FDA approval for broader use.Â
However, itâs worth checking with your insurance provider, as policies vary. For example, some may cover certain aspects of the spinal cord injury treatment, such as related tests or rehabilitation.
đ€ What does the cost of stem cell therapy include?
The cost of stem cell treatment for spinal cord injuries typically includes:
- Initial consultation and diagnosis. Doctors will assess the severity of the injury and determine the best treatment plan.
- Stem cell harvesting and processing. Depending on the type of stem cells, this may involve harvesting from the patientâs body or using donor cells. Specialists then process the collected stem cells to ensure clinical safety.
- Treatment administration. This covers the actual procedure, including any necessary equipment and medications.
â Additional inclusions in the package offers
Clinics catering to international patients often offer all-inclusive packages with extra services. They intend to make the process smoother and more cost-effective in the long run:
- Travel arrangements and airport transfers. Clinics can provide transportation between the airport, clinic, and hotel. If you decide to opt for Bookimedâs support, your personal coordinator can also assist you with booking flights.
- Accommodation. Packages may include hotel stays for the duration of the treatment, ranging from a few days to several weeks.
- Language assistance. Clinics may provide translators for international patients to ensure clear communication with the medical team.
- Rehabilitation services. Since functional recovery is critical for spinal injury patients, packages might also include physical therapy sessions to support the healing process.
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Spinal Cord Injuries and Stem Cell Therapy: How It Works
To make an informed decision, itâs important to understand how spinal cord injuries affect the body and how stem cell treatments work to repair the damage.
What do we know about spinal cord injuries?
A spinal cord injury disrupts the crucial connection between the brain and the rest of the body. This can result from trauma, such as car accidents, falls, or sports injuries, as well as from illnesses like tumors or infections.Â
There are two main types of spinal cord injuries:
- Complete spinal cord injury, where there is no function or sensation below the injury site, and
- Incomplete spinal cord injury, where there is some ability to move or feel, depending on the severity of the damage.
In addition to mobility issues, these injuries can cause:
- chronic pain;
- muscle spasms;
- complications with bladder, bowel, and respiratory functions.Â
The biggest challenge is that the spinal cord does not naturally regenerate, which limits recovery options. Thatâs why stem cell therapy is gaining attention as a potential breakthrough.
How can stem cell therapy help?
Stem cells are unique because they have the power to transform into many different types of cells in the body. Stem cell therapy aims to repair and regenerate damaged nerve cells in the spinal cord. Hereâs how it works:
- Cell replacement. Stem cells can transform into new, healthy nerve cells to replace the damaged ones.
- Repair & support. They release substances that support existing cells, modulate the inflammatory response, and promote tissue repair.
- Stimulated nerve growth. Stem cells can encourage the regrowth of nerve fibers (axonal regeneration), potentially restoring some lost functions.
đïž Hear Dr. Bernschina explain why stem cells are so precious:
đ€ How does stem cell therapy compare to conventional treatments for spinal cord injury?
Traditional therapies for spinal cord injury, like physical rehabilitation, primarily reduce symptoms and help patients adapt to their new limitations. These methods can improve mobility, manage pain, and support daily function.
On the other hand, stem cell therapy aims to repair and regenerate damaged nerve tissues. By promoting cell growth, reducing inflammation, and encouraging nerve regeneration, stem cell treatments target the root of the injury.
Different types of stem cells can be used for treating spinal cord injuries:
- Mesenchymal stem cells (MSCs). Often derived from bone marrow, adipose tissue (fat), or umbilical cords. Mesenchymal stem cells are known for their ability to reduce inflammation and repair tissue.
- Embryonic stem cells (ESCs). These are highly versatile stem cells, capable of developing into over 200 different cell types. They can rapidly proliferate and have great potential for repairing complex tissues, including the spinal cord. However, their use is limited by ethical concerns, risks of tumor formation, and the need for immunosuppressive drugs to prevent rejection.
- Induced pluripotent stem cells (iPSCs). Lab-engineered adult cells that act like embryonic ones. They show significant promise because they preserve the versatility of embryonic stem cells without the associated ethical issues.
- Neural stem cells (NSCs). Naturally inclined to develop into nerve cells, these are used specifically to address neurological damage and offer targeted repair.
Clinical trials and stem cell research
Various studies on stem cells for spinal injuries highlight improvements in mobility, sensory perception, and other crucial functions. Here are just some of the findings:
đ Yale University clinical trial
Yale University researchers tested how intravenous administration of bone marrow-derived MSCs would impact patientsâ motor skills. Over half of the patients showed significant improvements, such as walking and better hand coordination, within weeks after receiving stem cell injections.
The American Spinal Injury Association (ASIA) Impairment Scale was used to measure motor and sensory functions:
- At 6 months, 12 of 13 patients improved their ASIA grade.
- Notably, 5 patients improved from ASIA C (weak, limited movement) to ASIA D (stronger muscle control, more controlled movement) just one day after the infusion of mesenchymal stem cells.
đ Mayo Clinic study
A study conducted by the Mayo Clinic looked at the effectiveness of adipose-derived stem cells:
- 7 out of 10 participants showed better sensation, increased muscle strength, and improved bowel function.
- All participants moved up at least 1 level on the ASIA scale, reflecting tangible progress.
đ PrimeCell Therapeutics clinical trial
A clinical trial by a Californian biotechnology company further demonstrated that stem cell treatment can enhance patients' ability to walk, stand, and regain sensory perception:
- 60% of patients could stand up;
- 40% could walk on parallel bars with braces;
- 28% could walk without braces;
- 16% could walk using crutches.
Patients also showed better sensitivity, motor function, bladder control, and even improvements in sexual function.
âł Timing matters: Acute, subacute, and chronic spinal cord injury
Studies show that administering treatment soon after the injury is more effective than in the chronic phase, where scar tissue can hinder the growth of transplanted cells.Â
Yoon et al. found that 33.3% of patients treated early improved their ASIA scores. On the other hand, only 5.2% of patients with chronic spinal cord injury showed similar improvements. However, large doses of stem cells led to moderate improvements in motor and sensory scores even in chronic cases.
â Safety
Across all of the above studies, stem cell therapy has shown a good safety profile. No severe adverse events were consistently linked to the treatment.Â
Mild side effects included:
- headaches;Â
- musculoskeletal pain;
- gastrointestinal discomfort.Â
The side effects were manageable with standard medications.
What can you expect from the stem cell treatment procedure?
1. đ©ș Initial consultation & diagnosis
A thorough medical examination is needed to assess the extent of the injury and determine if stem cell therapy is appropriate. Specialists will review your medical history and conduct necessary tests.
2. đŹ Harvesting & processing
- Harvesting. Patientâs own stem cells are collected from bone marrow, fat tissue, or other sources. Alternatively, donor cells may be used (usually from a stem cell bank).
- Processing. In a lab, the stem cells are processed to ensure they are pure and viable for treatment.
3. đ Treatment session
There are two main types of stem cell administration for traumatic spinal cord injury:
- Intravenous administration. Stem cells are injected into the bloodstream, allowing them to circulate and reach the injury site. This method is less invasive and delivers supportive cells throughout the body.
- Intrathecal injection. Stem cells are injected directly into the cerebrospinal fluid surrounding the spinal cord. Intrathecal administration allows the cells to reach the injury site more directly, potentially increasing the effectiveness of the treatment.
4. đ©č Recovery & follow-up
Regular check-ups will let the doctor track your and change the course of treatment as needed. Stem cell treatment can also be combined with physical therapy to maximize the results.
Patient testimonials
Hearing from those who have already undergone stem cell treatment can provide valuable insight. Below are testimonials from Bookimed patients who have shared their experiences with stem cell treatments:
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All medical content on this page is prepared by authors with specialized medical education and reviewed by certified physicians in the relevant field. Medical review by Kayhan Turan , Orthopedic surgeon .
Last updated: June 20, 2025.
- Statistics: Figures are based on Bookimedâs internal database December 2025, which includes analysis of 12,450 patient requests across 5 accredited clinics in Mexico.
- Pricing: Cost information is provided directly by Bookimedâs partner clinics and updated regularly to reflect current 2025 market conditions. Actual expenses may differ depending on case complexity, surgeon expertise, and clinic location.
- Clinical Data: Treatment outcomes and patient satisfaction figures are collected from Bookimedâs verified clinic database and supported by data from peer-reviewed medical sources such as PubMed, The Lancet, JAMA, and NEJM (2023â2025).
All data is provided for general informational purposes and may not represent individual results or experiences.
- Mayo Clinic. (2024). Spinal Cord Injury. https://www.mayoclinic.org/diseases-conditions/spinal-cord-injury/symptoms-causes/syc-20377890
- Cleveland Clinic. (2023). Stem Cells. https://my.clevelandclinic.org/health/body/24892-stem-cells
- YaleNews. (2021). Yale scientists repair injured spinal cords using patients’ own stem cells. https://news.yale.edu/2021/02/22/yale-scientists-repair-injured-spinal-cords-using-patients-own-stem-cells
- Mayo Clinic News Network. (2024). Study documents safety, improvements from stem cell therapy after spinal cord injury. https://newsnetwork.mayoclinic.org/discussion/study-documents-safety-improvements-from-stem-cell-therapy-after-spinal-cord-injury/
- Frontiers in Immunology. (2023). Mesenchymal stem cells in the treatment of spinal cord injury: Mechanisms, current advances and future challenges. https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1141601/full