Omotesando HELENE Clinic is a regenerative medicine center in Tokyo, Japan. It specializes in autologous mesenchymal stem cell (MSC) and exosome-based therapies. The clinic opened in 2014 and treats adults across 19 departments. Its in-house Cell Processing Center meets ISO Class 5 cleanroom standards. The lab uses AI image analytics and barcode management for cell traceability.
In 2017, it became the world's first stem cell clinic to receive GCR certification. The clinic also holds ISO 9001 certification for quality management. It won the Quality Choice Prize in the Diamond category from the ESQR. Its 24 doctors take part in international research on MSC safety. Medical interpreters support patients in 13 languages, including English, Chinese, and French.
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Average answering time – 5 minutes
Omotesando HELENE Clinic is a private regenerative medicine facility in Tokyo's Omotesando district. Established in 2014, it operates from a single building dedicated to advanced cellular therapies. The clinic specializes in autologous adipose-derived mesenchymal stem cells (MSCs) and exosome-based treatments.
The clinic holds several quality credentials that validate its clinical and laboratory standards. It maintains ISO 9001 certification for quality management. In June 2017, the facility became the first stem cell clinic worldwide to receive GCR (Global Clinic Rating) certification.
The European Society for Quality Research has recognized the clinic with multiple awards:
The clinic has published peer-reviewed research on the safety of high-dose intravenous MSC administration. MEDTECH Outlook APAC named it a Top Regenerative Medicine Solution Provider in 2025.
The medical team focuses on autologous therapies, which use a patient's own cells to support healing. Physicians conduct detailed evaluations using medical history and in-house blood tests before starting any protocol. Each patient receives a dossier with certified laboratory reports for every procedure.
Specialists offer targeted treatments for several indications:
The rehabilitation department supports stroke recovery. Protocols address motor impairments, cognitive issues, and autonomic nervous system disorders. The team provides guidance for both the acute phase and long-term recovery after hospital discharge.
The clinic operates the Omotesando Cell Culture Lab, a dedicated Cell Processing Center (CPC). This facility manages the entire cellular workflow – from collection and storage to cultivation and testing. The lab meets standards equivalent to Good Manufacturing Practice (GMP).
Safety protocols include several technical safeguards:
Stem cell quantification follows a multi-stage verification workflow. Staff confirm cell count and viability at least twice using ZEISS Axio Vert.A1 microscopy. Proprietary AI image analytics then assess cell activity before preparation.
Omotesando HELENE Clinic treats international patients through a specialized multilingual team. Medical interpreters help with consultations and coordination. The team supports over 10 languages, including English, Chinese, French, Korean, and Vietnamese.
Patients can access online pre-consultations before traveling to Japan. These sessions let physicians review medical records and discuss treatment options remotely. After treatment, patients rest in a dedicated recovery area. Staff provide home-care instructions and emergency guidance before discharge.
The clinic is not accepting new requests
Average answering time – 5 minutes