Bone marrow transplantation in United States of America: Our Best Clinics and Costs 2024

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Bone marrow transplantation Overview in United States of America

Takeaways
Related procedures & Costs
How it works
What to expect
Benefits
Payment
patients recommend -
85%
Surgery Time - 4 hours
Stay in the country - 90 days
Rehabilitation - 180 days
Anesthesia - General anesthesia
Requests processed - 6882
Bookimed fees - $0

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Content meets the Bookimed Editorial Policy and is medically reviewed by
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Updated: 5/27/2022
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Our Bone marrow transplantation Techniques: What Suits You Best?

When considering Bone marrow transplantation, it’s important to understand the different techniques and which is best suited for you. Here’s a concise comparison of popular options:

Autologous Bone Marrow Transplantation

This procedure involves collecting stem cells from a patient's own bone marrow, processing them, and reinfusing to aid in recovery, especially for cancer treatment, with minimal rejection risk.

Pros: Minimal risk of graft-versus-host disease (GVHD) as it uses the patient's cells. No need for donor matching, making it suitable for certain blood disorders and cancers.
Cons: Requires general anesthesia for cell collection, potentially causing pain and fatigue. Higher relapse rates in some cancers compared to donor transplants.
Effectiveness: Increases survival rates and quality of life in blood-related cancers and disorders.
Duration: 3-5 hours.
Recovery: 1-3 months for initial recovery, full immune recovery up to 12 months.
Best for: Blood cancers like leukemia and lymphoma; beneficial when chemotherapy is insufficient.

Allogenic Bone Marrow Transplantation from a Related Donor

This procedure involves transferring healthy stem cells from a closely matched family member to replace damaged bone marrow in patients with certain diseases.

Pros: Higher success rates due to better donor matching with a related donor, reducing graft-versus-host disease (GVHD) risks. Engraftment is typically faster with 70-90% success.
Cons: Requires a compatible family donor; there is a risk of GVHD despite close matching. Availability of a suitable donor can be limited.
Effectiveness: Success rate is 70-90% with related donors.
Duration: 1-2 hours for the procedure, with additional days for preparation and recovery.
Recovery: Initial recovery takes 3-6 weeks; complete recovery can take several months.
Best for: Blood cancers like leukemia and lymphoma, and certain genetic disorders. Ideal for patients with a suitable family donor.

Allogenic Bone Marrow Transplantation from an Unrelated Donor

This procedure involves transplanting stem cells from a donor who is not genetically related to the recipient, used primarily for treating blood-related diseases.

Pros: Offers a wider donor pool, increasing chances of finding a match. Provides a potential cure for conditions where related donors are unavailable.
Cons: Higher risk of graft-versus-host disease (GVHD) compared to related donor transplants. Requires stringent donor matching, potentially delaying treatment.
Effectiveness: Success rates vary but can be as high as 60-70% in certain conditions.
Duration: The procedure typically takes 1 day for infusion, with 2-4 weeks for engraftment.
Recovery: Recovery period can last 3-6 months, with full immune system recovery taking up to a year.
Best for: Suitable for leukemia, lymphoma, and other serious blood disorders where a related donor is not available.

Haploidentical Stem Cell Transplantation

Involves using stem cells from a half-matched donor, typically a family member, to treat various blood disorders and cancers.

Pros: Availability of donor is higher due to partial match requirement, covering 50% of potential related donors. Reduced waiting time for suitable donor compared to unrelated allogenic transplants.
Cons: Higher risk of graft-versus-host disease (GVHD) compared to fully matched donors, with around 30% incidence rate. Requires more intense conditioning regimens.
Effectiveness: 60-80% success rate in achieving engraftment and remission in certain blood cancers.
Duration: 4-6 hours for the procedure itself.
Recovery: 3-6 months for full recovery and immune reconstitution.
Best for: Patients with leukemia and other hematological malignancies lacking a fully matched donor. Suitable for urgent transplant needs.