Best Alzheimer's disease neurologists in Istanbul: TOP 25 doctors

Dr. Baris Metin is an experienced Neurologist with over 7 years of experience in Turkey and Belgium. He specializes in Memory Disorders, Functional Neuroimaging, Epilepsy, Electroencephalography, Headaches and Sleep Disorders, and has numerous research papers in national and international scientific journals.

Gülümser Kızıltaş Tokmak, M.D., graduated from Cerrahpaşa School of Medicine, Istanbul University in 2002 and completed residency at Neurology Clinic, Okmeydanı Teaching and Research Hospital in 2008. She holds a master’s degree in Electrophysiology from Istanbul University, and has studied and worked in fields such as EMG, EEG, PSG, Dementia, Headache, and Vertigo. She has worked at Ağrı State Hospital Neurology Clinic, Hisar Intercontinental Hospital, and Medical Park Hospitals.

Dr. Tamer Atasever is a Nuclear Medicine Specialist with 39 years of experience, speaking English and Turkish. He is a professor in Gazi University and has been a director of the Department of Nuclear Medicine in Ankara Order Laboratory. He is a member of the Turkey Association of Nuclear Medicine and the European Association of Nuclear Medicine.

Neurosurgery Training: Gazi University, Department of Neurosurgery, 2011 

H index: 10, I10 Index: 12 Citations: 296

 Dr Mehmet Tonge has international and nationwide 32 publications, 12 book chapters, 92 oral and poster presentations and 41 invited lectures, mostly on Stereotactic and Functional Neurosurgery. 

Work & Training experience:

2004-2011: Gazi University, Department of Neurosurgery (Residency)

 2008: Zurich University Hospital, Department of Neurosurgery (Intraoperative MRI applications), Switzerland 

2008: Zurich University Hospital, Department of Neurosurgery: Microneurosurgery, white matter dissection, interventional neuroradiology courses, Switzerland 

2011 – 2012: Sinop Ataturk State Hospital, Neurosurgeon

 2012 – 2013: Cankiri State Hospital, Neurosurgeon 

2013 – 2014: Istanbul Medipol University, Department of Neurosurgery & Gamma Knife Center (Ass Prof) 

2013 – now: Maastricht University Neurosurgery & Neuroscience Department (Visiting scientist, PhDc) The Netherlands 

2014: Maastricht University, The Netherlands: Deep Brain Stimulation Fellowship 2014-2018: Istanbul Memorial Hospital Neurosurgery: Staff Neurosurgeon

 2016-2018: Istanbul Florence Nightingale Hospital (Consultant, Gamma Knife Center) 

2018-now: Istanbul Medipol University (Stereotactic & Functional Neurosurgery, Gamma Knife Center) Ass. Prof.) 

Dr Mehmet Tonge has completed 4-year cycle EANS (European Association of Neurosurgical Societies) Training courses. 

Clinical areas of interest:

 • Stereotactic & Functional Neurosurgery

 • Surgery for movement disorders

• * MR Guided Focused Ultrasound (MRgFUS)

 • Gamma Knife Radiosurgery 

• Surgery for pain & spasticity 

• Psychosurgery

Research areas of interest: 

• Deep brain stimulation

• * MR Guided Focused Ultrasound (MRgFUS)

 • Stereotactic radiosurgery 

Administrative duties:

 • Turkish Neurosurgical Society, Sterotactic & Functional Neurosurgery Section: Board member 2015- 2017 

• Turkish Neurosurgical Society, Sterotactic & Functional Neurosurgery Section: Board member (Secretary) 2017-2019

 • Turkish Skull Base Society: Board member 2016-2018

 • Turkish Skull Base Society: Supervisory board member 2018-2020

 • Deep Brain Stimulation and Movement Disorders Surgery Society: Executive Board Member, (Accountant) 2023-still 

Memberships: 

• WSSFN (World Stereotactic & Functional Neurosurgery Society) 

• ESSFN (European Stereotactic & Functional Neurosurgery Society)

 • Deep Brain Stimulation and Movement Disorders Surgery Society

 • Deep Brain Stimulation Society 

• International Stereotactic Radiosurgery Society 

• Leksell Gamma Knife Society 

• EANS (European Association of Neurosurgical Societies) 

• Turkish Neurosurgical Society

• Turkish Skull Base Society

Sample Publications: 

1. Tonge M. Technological developments in electric based DBS. Deep Brain Stimulation 2024 4(36-41) DOI: https://doi.org/10.1016/j.jdbs.2023.12.001 

2. Akgul E, Onan HB, Islek I, Tonge M, Durmus Y, Barburoglu M, Azizova A, Erol C, Hakyemez B, Sencer S, Aydin K, Arat A. Flow diverter stents in the treatment of recanalized intracranial aneurysms. Interv Neuroradiol. 2021 Aug;27(4):481-489. doi: 10.1177/1591019921990507. Epub 2021 Jan 28. PMID: 33509011; PMCID: PMC8580529. 

3. Mulders AEP, Temel Y, Tonge M, Schaper FLWVJ, van Kranen-Mastenbroek V,Ackermans L, Kubben P, Janssen MLF, Duits A. The association between surgical characteristics and cognitive decline following deep brain stimulation of the subthalamic nucleus in Parkinson's disease. Clin Neurol Neurosurg. 2021 Jan;200:106341. doi: 10.1016/j.clineuro.2020.106341. Epub 2020 Nov 3. PMID: 33160716. 

4. Wetzelaer P, Vlis T, Tonge M, Ackermans L, Kubben P, Evers S, Kocabicak E, Temel Y. Management of Hardware Related Infections after DBS Surgery: A Cost Analysis. Turk Neurosurg. 2018;28(6):929- 933. doi: 10.5137/1019-5149.JTN.21511-17.1. PMID: 29465741. 

5. Bedirli N, Emmez G, Ünal Y, Tönge M, Emmez H. Effects of positive end- expiratory pressure on intracranial pressure during pneumoperitoneum and Trendelenburg position in a porcine mode. Turk J Med Sci. 2017 Nov 13;47(5):1610-1615. doi: 10.3906/sag-1609-17. PMID: 29152942. 

6. Sari R, Tonge M, Bolukbasi FH, Onoz M, Baskan O, Silav G, Elmaci I. Management of Failed Cranioplasty. Turk Neurosurg. 2017;27(2):201-207. doi: 10.5137/1019-5149.JTN.15395-15.0. PMID: 27593759. 

7. Tonge M, Kocabicak E, Ackermans L, Kuijf M, Temel Y. Final Electrode Position in Subthalamic Nucleus Deep Brain Stimulation Surgery: A Comparison of Indirect and Direct Targeting Methods. Turk Neurosurg. 2016;26(6):900-903. doi: 10.5137/1019-5149.JTN.13739-14.1. PMID: 27337232. 

8. Tonge M, Ackermans L, Kocabicak E, van Kranen-Mastenbroek V, Kuijf M, Oosterloo M, Kubben P, Temel Y. A detailed analysis of intracerebral hemorrhages in DBS surgeries. Clin Neurol Neurosurg. 2015 Dec;139:183-7. doi: 10.1016/j.clineuro.2015.10.017. Epub 2015 Oct 23. PMID: 26513430. 

9. Silav G, Bölükbaşı FH, Özek E, Tönge M, Önöz M, Elmacı İ. A Simple Technique for Bone Storage after Decompressive Craniectomy in Children. Pediatr Neurosurg. 2015;50(3):161-4. doi: 10.1159/000381748. Epub 2015 May 14. PMID: 25998533. 

10. Yilmaz MB, Donmez H, Tonge M, Senol S, Tekiner A. Vertebrojugular arteriovenous fistula and pseudoaneurysm formation due to penetrating vertebral artery injury: case report and review of the literature. Turk Neurosurg. 2015;25(1):141-5. doi: 10.5137/1019-5149.JTN.8247-13.1. PMID: 25640560. 

11. Kurt G, Tönge M, Çeltıkçı E, Çapraz I, Serdaroğlu A, Bılır E. Surgery for intractable temporal lobe epilepsy: experience of a single institution. Turk J Med Sci. 2014;44(5):866-70. doi: 10.3906/sag-1307- 30. PMID: 25539559. 

12. Yılmaz MB, Tönge M, Emmez H, Kaymaz F, Kaymaz M. Neuroprotective effects of quetiapine on neuronal apoptosis following experimental transient focal cerebral ischemia in rats. J Korean Neurosurg Soc. 2013 Jul;54(1):1-7. doi: 10.3340/jkns.2013.54.1.1. Epub 2013 Jul 31. PMID: 24044072; PMCID: PMC3772279. 

13. Yilmaz MB, Egemen E, Tonge M, Kaymaz M. Transoral protrusion of a peritoneal catheter due to gastric perforation 10 years after a ventriculoperitoneal shunting: case report and review of the literature. Turk Neurosurg. 2013;23(2):285-8. doi: 10.5137/1019-5149.JTN.4904-11.1. PMID: 23546921. 

14. Omerhodzic I, Tonge M, Matos B, Musabeliu E, Raspanti C, Ferdinandov D, Galimova R, Muroi C, Balik V, Kursumovic A. Neurosurgical training programme in selected European countries: from the young neurosurgeons' point of view. Turk Neurosurg. 2012;22(3):286-93. doi: 10.5137/1019- 5149.JTN.5133-11.0. PMID: 22664994. 

15. Ergun E, Kurt G, Tonge M, Aytar H, Tas M, Baykaner K, Ceviker N. Effects of phenytoin sodium on dura mater healing in a rat model of CSF leakage. Turk Neurosurg. 2011;21(4):471-6. PMID: 22194102. 

16. Emmez H, Tonge M, Tokgoz N, Durdag E, Gonul I, Cevıker N. Radiological and histopathological comparison of microporous polysaccharide hemospheres and oxidized regenerated cellulose in the rabbit brain: a study of efficacy and safety. Turk Neurosurg. 2010 Oct;20(4):485-91. doi: 10.5137/1019- 5149.JTN.3300-10.2. PMID: 20963698. 

17. Emmez H, Yildirim Z, Kale A, Tönge M, Durdağ E, Börcek AO, Uçankuş LN, Doğulu F, Kiliç N, Baykaner MK. Anti-apoptotic and neuroprotective effects of α-lipoic acid on spinal cord ischemiareperfusion injury in rabbits. Acta Neurochir (Wien). 2010 Sep;152(9):1591-600; discussion 1600-1. doi: 10.1007/s00701-010-0703-9. Epub 2010 Jun 10. PMID: 20535507. 

18. Kurt G, Tonge M, Börcek AO, Karahacioglu E, Gurel O, Baykaner K, Ceviker N, Aykol S. Fractionated gamma knife radiosurgery for optic nerve tumors: a technical report. Turk Neurosurg. 2010 Apr;20(2):241-6. doi: 10.5137/1019-5149.JTN.1681-09.3. PMID: 20401852. 

19. Emmez H, Kale A, Tönge M, Cakir A, Ceviker N. Two meningiomas with different histological grades in the same patient. Case report. Neurol Med Chir (Tokyo). 2010;50(8):686-8. doi: 10.2176/nmc.50.686. PMID: 20805656.

2002-2007 Istanbul University Istanbul Faculty of Medicine Department of Brain and Nerve Surgery

1988-1995 Trakya University Faculty of Medicine

2015- Atlas University Medicine Hospital

2014-2015 Private Pendik Yüzyıl Hospital Brain and Neurosurgery Clinic

2009-2014 Medicine Hospital Brain and Neurosurgery Clinic

2009-2009 Nisa Hospital Brain and Neurosurgery Clinic

2007-2009 Mardin State Hospital Brain and Neurosurgery Clinic

2002-2007 Istanbul University Istanbul Faculty of Medicine Brain and Neurosurgery

1997-2001 Enez Health Center and Enez State Hospital

Cervical, Thoracic and Lumbar Disc Surgery (endoscopic/microsurgery)

Far lateral (non-canal) lumbar disc surgery (lateral microsurgical approach)

Neurovascular surgery

Cerebrovascular diseases (vascular diseases of the brain)

Aneurysms

Arteriovenous malformations

Cavernomas

Neuro-oncological surgery

Brain tumors

Glial tumors

Meningiomas

Pituitary gland tumors

Metastatic brain tumors

Skull base tumors

Pontocerebellar angle tumors

Pineal tumors

Intraventricular tumors

Spinal disease surgery

Cervical, thoracic and lumbar spine fractures

Spine and spinal cord tumors

Scoliosis

Degenerative spine diseases

Peripheral nerve disease surgery

Peripheral nerve tumors

Entrapment neuropathies

Carpal tunnel syndrome

Ulnar groove syndrome

Tarsal tunnel syndrome

Functional neurosurgery and pain surgery

Trigeminal neuralgia

Microvascular decompression

Epilepsy surgery

Spasticity surgery

Epiduroscopic interventions

Hydrocephalus surgeries

Endoscopic 3rd ventriculostomy

VP shunt surgeries

LP shunt surgeries

Developmental anomalies

Meningomyelocele

Tethered cord syndrome

Arachnoid cyst

Craniosynostosis surgeries

Chiari malformation

Head trauma

Subdural hematomas

Intracerebral hematomas

Article published in internationally refereed journals

Cansever T, Civelek E, Sencer A, Karasu A, Kiris T, Hepgül K, Can H, Canbolat A: Spinal cavernous malformations: a report of 5 cases. Surg Neurol Jun 69 

Effects of combined and individual use of N-methyl-D aspartate receptor antagonist magnesium sulphate and caspase-9 inhibitor z-LEDH-fmk experimental spinal cord injury. A.Sencer, A.Aydoseli, Y.Aras, M.Osman Akçakaya, C.Gömleksiz, H.Can, A.Canbolat. Turkısh Joumal of Trauma&Emergency Surgery 2013

Aydoseli A, Can H, Aras Y, Sabanci PA, Akcakaya MO, Unal OF. Memantine and Q-VD-OPh Treatments in Experimental Spinal Cord Injury: Combined Inhibition of Necrosis and Apoptosis. Turk Neurosurg. 2016

Can H, Kircelli A, Kavadar G, Civelek E, Cansever T, Aydoseli A, Onal MB, Yilmaz C. Lumbosacral Conjoined Root Anomaly: Anatomical Considerations of Exiting Angles and Root Thickness. Turk Neurosurg. 2017

Kırcelli A, Özel Ö, Can H, Sarı R, Cansever T, Elmacı İ. Is the presence of linear fracture a predictor of delayed posterior fossa epidural hematoma? Ulus Travma Acil Cerrahi Derg. 2016 Jul

Kavadar G, Demircioğlu DT, Can H, Emre TY, Civelek E, Senyigit A. The clinical factors associated with benefit finding of complementary medicine use in patients with back pain: A cross-sectional study with cluster analysis. J Back Musculoskelet Rehabil. 2017

Ozer AF, Suzer T, Can H, Falsafi M, Aydin M, Sasani M, Oktenoglu T. Anatomic Assessment of Variations in Kambin’s Triangle: A Surgical and Cadaver Study. World Neurosurg. 2017 Apr

Can H, Aydoseli A, Gömleksiz C, Göker B, Altunrende ME, Dolgun M, Sencer A. Combined and individual use of pancaspase inhibitor Q-VD-OPh and NMDA receptor antagonist riluzole in experimental spinal cord injury. Ulus Travma Acil Cerrahi Derg. 2017

Gomleksiz C, Erbulut DU, Can H, Kodigudla MK, Kelkar AV, Kasapoglu E, Ozer AF, Goel VK. A new lumbar fixation device alternative to pedicle-based stabilization for lumbar spine: In vitro cadaver investigation. J Spinal Cord Med. 2018 Jul 16:1-8.

Aydoseli A, Özgen U, Akgül T, Orhan EK, Adıyaman AE, Can H, Karadağ C. Subacute Traumatic Ascending Myelopathy in a 28-year-old man: A rare case. World Neurosurg. 2019 Apr 28

Article published in national refereed journals

1) Intracranial Hemangioblastomas: Clinical Evaluation of 32 Patients T. Cansever, A. Karasu, K. Hepgül, H. Can, A. Sencer Turkish Neurosurgical Journal 2007, Volume:17 

2) Halil Can, Müge Dolgun, Utku Özgen, Cengiz Gömleksiz, Furkan Diren, Aydın Aydoseli, Yavuz Aras, Altay Sencer. Microsurgical Results in Vestibular Schwannoma Patients; Retrospective Clinical Study. JAREM 2019

3) Furkan Diren , Özcan Gayretli , Halil Can , İlke Ali Gürses , Orhan Barlas. Examination of Pons-Cerebellum Cisterna Anatomy with Endoscopic Retrosigmoid Suboccipital Approach: Cadaver Study. JAREM 2019

Dr. Nesrin Helvacı Yılmaz is a neurology specialist based in Turkey and has over 10 years of medical experience. She has a degree in general medicine from Hacettepe University Medical School, a specialty in neurology from Ankara University Medical School, a specialty in general medicine from Silivri Kolan Hospital, and a specialty in nephrology from Istanbul University. She is a member of The Turkish Neurological Society, The Turkish Medical Association, and The Turkish Association of Sleep Medicine.

Specialist of regenerative medicine

Medical Interests

• Demyelinating Diseases and MS

• Peripheral Neuropathy and Motor Neuron Disease (ALS)

• Neuromuscular Junction Diseases (MG)

• Movement Disorders and Parkinson's Disease

• headaches

• Alzheimer's and other Dementias

• Epilepsy

Education

• Faculty of Medicine Ondokuz Mayıs University 1990

• Neurology Ankara Training and Research Hospital 1997

• Clinical Neurophysiology Medical Specialization Board 2011

Experience

• MoH Kastamonu and Samsun Health Center No. 7 1990-1992

• Ankara Training and Research Hospital Neurology Clinic 1992-1997

• Abant İzzet Baysal University Düzce Faculty of Medicine 1999-2006

• Düzce University Faculty of Medicine 2007-2011

• Düzce University Faculty of Medicine 2011-2021

• Liv Vadi Istanbul 2021-

Memberships

• Turkish Neurological Society

• Turkish Society of Clinical Electrophysiology

• Istanbul Medical Chamber

General Information and Presentation

He completed his primary education at Şenlikköy Primary School and his secondary education at the Istek Foundation Florya Bilge Kagan High School. He graduated from Istanbul University Cerrahpaşa Faculty of Medicine in 2001. He completed his specialist education in Istanbul Medical Faculty Neurology Department in 2006. In 2006 he worked at the Neurology Clinic and the PharmaZentrum Research Center of the Faculty of Medicine of the University of Basel, Switzerland. Between 2007 and 2011, Bakırköy Prof. Dr. He worked at Mazhar Osman Mental Health and Neurological Diseases Training and Research Hospital in the 3rd Neurology Clinic and in the Dementia and Movement Disorders policlinics. Since October 2011, he has been working at Istanbul University of Science, Faculty of Medicine, Neurology, USA.

Experience

İstanbul Bilim University Faculty of Medicine Neurology, 

Şişli Florence Nightingale Hospital 

Kadıköy Florence Nightingale Hospital Neurology Clinics, 

Gayrettepe Metropolitan Florence Nightingale Hospital PET department.

Assoc. Prof.  Nesrin Helvacı Yılmaz graduated from Hacettepe University in 2000 as a Medical Doctor.  She completed her specialty training in the Department of Neurology at Ankara University in 2006.

She started her compulsory service in Mardin Nusaybin State Hospital in 2007.  Nesrin Helvacı Yılmaz continued her duty in Gaziantep 27 December State Hospital in 2008.  She worked as a neurologist at Biophysis Nilüfer Medical Center and Ali Osman Sönmez Oncology Hospital in Bursa between 2010-2011, and at Istanbul Universal Aksaray Hospital between 2011-2012. From October 2012, she started to work as a Doctor Lecturer in Istanbul Medipol University Neurology Department.  Nesrin Helvacı Yılmaz received the title of associate professor in 2021.  In 2015, she worked as an Honorary Observer in Parkinson's Disease and Deep Brain Stimulation (Neuromodulation) at UCL Queen Square Institute of Neurology, National Hospital for Neurology in London.  She took part in many training programs on Deep Brain Stimulation (Neuromodulation) in Turkey and abroad between 2013-2022.

Regarding her speciality in Parkinson's disease and movement disorders, she has 5 Tubitak projects, a 2-chapter book , 30 clinical researches and 80 reports presented in domestic and abroad. Assoc. Prof. Nesrin Helvacı Yılmaz, who is still working within the staff of Medipol University, managed the Parkinson's and Movement Disorders Unit of the Department of Neurology during her working time and plans Deep Brain Stimulation therapy applications with the neurosurgical team.

Since September 2018, she has been working as a coordinator for student education in the 5th semester of Neurology. As of December 2022, she has developed treatment plans for patients at Medipol University Istanbul Parkinson's Disease and Movement Disorders Center (PARMER) and provides the most appropriate personal medical follow-up and treatment support for each patient.

PUBLICATIONS

1-Yilmaz N, Yigit A, Akbostanci MC. Clozapine induced epilepsy. Revue Neurologique 2004, Nov;160/11:1093.

2-Nesrin Helvacı Yılmaz, Nursel Aydın. Sıcak Su Epilepsili Bir Olgu. Türkiye Klinikleri Nöroloji Dergisi 2004/Cilt2/Sayı 2.

3-Nesrin Helvacı Yılmaz, Nursel Aydın. Refleks Epilepsiler. Türkiye Klinikleri Nöroloji Dergisi 2004/Cilt2/Sayı 2.

4-Mine Hayriye Sorgun, Bilge Koçer, Funda Kaplan, Nesrin Yılmaz, Nezih Yücemen, Canan Yücesan. Multipl Sklerozda Kraniyal Nöropati. Turk Norol Derg 2011;17:137-142.

5-Nesrin Helvacı Yılmaz, Gökçen Duymaz, Mehmet Akif Yaşar. Parkinson Hastalığı Olan Bir Olguda Malign Sendrom. Turk Norol Derg 2012:18;123-125.

6-Yilmaz NH, Akbostanci MC, Oto A, Aykac O. Prevalence of restless legs syndrome in Ankara, Turkey: an analysis of diagnostic criteria and awareness. Acta Neurol Belg 2012 Oct 31. [Epub ahead of print].

7-Yılmaz NH, Bingol AP. Sensitivity and specificity of Ankara University Cerebral Dominance Inventory in comparison with the Wada test. Acta Neurol Belg 2013 Jun 6 [Epub ahead of print].

8-Sema Demirci, Nesrin Helvacı Yılmaz, Efsun Şenocak, Fatih Han Bölükbaşı. Pons Kavernomu: Kranial Manyetik Rezonans Görüntüleme Bulguları. Turk Norol Derg 2012:19:72.

9-Nesrin Helvacı Yılmaz, Sinem Atik Güngör, Taflan Sahlepçi. Küçük hücreli akciğer kanseri tedavisinde cisplatin kullanımı sırasında gelişen akut iskemik inme: olgu sunumu. J Kartal TR. Baskıdaki Makaleler: KEAH-26937.

POSTERLER:

-Serebral venöz tromboz ve bruselloz Birlikteliği; Olgu Sunumu (42. Ulusal Nöroloji Kongresi-Antalya 2006)

-Waldenström makroglobulinemisine eşlik eden epileptik nöbetler ve nonkonvülsif status epileptikus (42. Ulusal Nöroloji Kongresi-Antalya 2006)

-Prevalence of Restless Legs Syndrome in Ankara, Turkey (16. Uluslararası Parkinson ve Hareket Bozuklukları Kongresi-Dublin 2012).

-Konjenital Miyastenik Sendrom (29. Ulusal Nörofizyoloji EEG-EMG Kongresi- Antalya 2013).

-Beşinci haftada duyusal iletimleri normal olan bir enjeksiyon nöropatisi olgusu (29. Ulusal Nörofizyoloji EEG-EMG Kongresi- Antalya 2013).

-Olgu sunumu: Mononöritis mültipleks ve lepra (29. Ulusal Nörofizyoloji EEG-EMG Kongresi- Antalya 2013).

-İdyopatik Parkinson Hastalığı’nda hızlanmış unutma ve uyku kalitesi (10. Ulusal Parkinson ve Hareket Bozuklukları Kongresi-Antalya 2013).

-Hiperglisemiye bağlı hemikore ve bazal gangliyon hiperintensitesi: Olgu sunumu (10. Ulusal Parkinson ve Hareket Bozuklukları Kongresi-Antalya 2013).