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Best Targeted therapy doctors in Ramat Gan: TOP 9 doctors

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Einat Shacham Shmueli

  • 26 years of experience
  • Location: Israel, Ramat Gan
  • Dr. Einat Shacham‑Shmueli is a senior medical oncologist at the Gastrointestinal Clinic, Cancer Center, Sheba Medical Center. She treats cancers of the colon, stomach, and pancreas. She also manages metastatic disease. She uses precision diagnostics and biomarkers, systemic therapies, and radiotherapy. Care is provided within a multidisciplinary team.

    She has authored more than 25 peer‑reviewed papers on GI oncology, tumor biology, and new treatments. Her work includes studies on stenting for malignant colonic obstruction. She serves as an investigator in international programs, including the NCI, the Radiation Therapy Oncology Group, and the Cancer Therapy Evaluation Program.

    Education: MD, Tel Aviv University. Oncology residency, Tel Aviv Sourasky Medical Center. Advanced training in GI oncology, UCSF. Accreditations: Board certified in Oncology and Gastroenterology. Member, Israel Society of Oncology and Radiotherapy.

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Yuri Goldes

  • 28 years of experience
  • Location: Israel, Ramat Gan
  • Dr. Yuri Goldes is a general surgeon with more than 20 years of clinical experience. He specializes in upper gastrointestinal and oncologic surgery. He is Deputy Director of the Department of General Surgery and Transplantation at Sheba Medical Center in Tel Aviv. He also leads the Upper GI Surgery Unit. He was named to Forbes Israel’s Best Doctors in 2025. He is ranked among Israel’s Best Gastrointestinal Surgeons by Forbes. In 2019, he received the Israeli Ministry of Health “Best Doctor of the Year” award.

    He is an expert in advanced minimally invasive and robotic surgery. He treats diaphragmatic hernia, achalasia, GERD, and gallbladder disease. He also performs oncologic surgery for pancreatic, gastric, and esophageal cancers. He uses laparoscopic and robotic techniques.

    He pioneered some of Israel’s first robotic oncologic resections of the stomach and pancreas. He is among a small group worldwide who perform minimally invasive Whipple procedures (pancreaticoduodenectomy) using advanced laparoscopy. He applies methods that improve outcomes and speed recovery. He provides personalized care.

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Amit Tirosh

  • 26 years of experience
  • Location: Israel, Ramat Gan
  • Prof. Amit Tirosh leads the Neuroendocrine Tumors Service at Sheba Medical Center – a top specialist for complex NET cases.

    • Expert in hereditary NET syndromes like MEN1 and VHL
    • Head of Endocrine Oncology Bioinformatics Lab
    • Advanced training at NIH in endocrine tumor genetics
    • Published 40+ papers on NET treatments
    • Main physician at Sheba's multidisciplinary VHL clinic
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Raanan Berger

  • 27 years of experience
  • Location: Israel, Ramat Gan
  • Professor Raanan Berger, MD PhD, is a medical oncologist and radiotherapist. He is Director of the Cancer Center at Sheba Medical Center and heads its clinical research unit. He was listed in Forbes Israel’s “Best Doctors” (2025). He leads the genitourinary oncology program with a focus on prostate cancer. His care includes systemic therapy and radiotherapy in a multidisciplinary, patient-centered model.

    He is board-certified in oncology. He earned his MD and PhD at Tel Aviv University and completed his clinical training at Sheba. He then completed a postdoctoral fellowship at Dana-Farber/Harvard, focusing on prostate cancer with Dr. Philip Kantoff and molecular oncology in Dr. William C. Hahn’s lab. He is a member of ESMO and ASCO. He has co-authored more than 20 peer-reviewed papers, including studies on outcomes in high- versus very high-risk prostate cancer and on BRCA1/2 in large cohorts.

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Nir Kleinmann

  • 25 years of experience
  • Location: Israel, Ramat Gan
  • Dr. Nir Kleinmann, MD, directs the Endourology and Kidney Stones Unit at Sheba Medical Center. He is an expert in minimally invasive urology and urologic oncology. His focus is the kidney and upper urinary tract. He was named among Israel’s Best Doctors for 2025–2026 by Forbes and ResultMed.

    He is a pioneer of kidney‑sparing laser surgery. He uses a dual‑laser system with neodymium and holmium for complex tumors. His expertise includes UTUC, kidney and prostate cancer, kidney stones, and BPH.

    His research includes the OLYMPUS trial on chemoablation for UTUC. He has more than 60 publications.

    He is an Israeli board‑certified urologist. He is a Fellow of the American Endourology Society and a member of the Israeli Urological Association and the EAU. He completed fellowships in Endourology and Minimally Invasive Surgery at Thomas Jefferson University. He also completed a fellowship in Kidney Cancer Research at McMaster University.

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Jair Bar

  • 35 years of experience
  • Location: Israel, Ramat Gan
  • Professor Jair Bar, MD, PhD, is a thoracic oncologist and Deputy Director of the Cancer Center at Sheba Medical Center. He leads the Thoracic Oncology Unit. He treats lung cancer, including advanced non-small cell cases. His care includes medical oncology, radiotherapy, immunotherapy, and targeted therapy.

    He runs a translational research lab focused on resistance to immunotherapy. He has published on exhaled-breath cancer metabolism and on angiogenesis inhibition in lung cancer.

    He has chaired the Israel Lung Cancer Group since 2003. He is a member of the Israel Society of Clinical Oncology and Radiotherapy, the American Society of Clinical Oncology, and the American Association for Cancer Research. He is board-certified in Medical Oncology and Radiotherapy Oncology. He is a Senior Lecturer at Tel Aviv University.

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Eytan Aharon Ben-ami

  • 20 years of experience
  • Location: Israel, Ramat Gan
  • Dr. Eytan Aharon Ben‑Ami, MD, is a Senior Physician in the Sarcoma and Bone Oncology Service at Sheba Medical Center. He heads the Oncology Division and the Early-Phase Clinical Trials Unit. He founded the Sheba Clinical Research Organization. He is an academic affiliate at Tel Aviv University.

    He specializes in sarcomas and primary bone tumors, including soft tissue sarcoma, liposarcoma, leiomyosarcoma, and osteosarcoma. He leads Phase I trials in targeted therapy and immunotherapy. He designs personalized treatment plans for rare cancers. He also develops patient-centered programs, including pilots in advanced immunotherapy delivery.

    He completed a fellowship in Sarcoma and Bone Oncology at the Dana-Farber Cancer Institute/Harvard Cancer Center. He has authored more than 40 publications on early detection, molecular and viral mechanisms, and new cancer therapies.

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Yaacov Lawrence

  • 31 years of experience
  • Location: Israel, Ramat Gan
  • Dr. Yaacov Lawrence, MA, MBBS, MRCP, is Chair of Radiation Oncology at Sheba Medical Center. He has nearly 30 years of experience in precision radiation oncology and neuro-oncology.

    He is an expert in advanced radiation therapy and radiosurgery. He performs stereotactic radiosurgery for brain tumors. He leads Sheba’s GI Cancer Program in gastrointestinal oncology. He also provides precision care for lung and prostate cancers. He pioneered celiac plexus radiosurgery for severe pain from pancreatic cancer.

    Training and credentials: MA and MBBS (Cambridge and UCLH); MRCP (RCP); Radiation Oncology fellowship (Thomas Jefferson University). Honors include the ASCO Young Investigator Award and Fellow of ASTRO (FASTRO). He has authored over 280 publications. He is Director of the Center for Translational Radiation Oncology and an Associate Professor at Tel Aviv University.

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Beni Boursi

  • 21 years of experience
  • Location: Israel, Ramat Gan
  • Prof. Ben Boursi specializes in gastrointestinal oncology and microbiome research, pioneering innovative cancer therapies at Sheba Medical Center.

    • Trained in gastrointestinal oncology at the University of Pennsylvania
    • Founder of the ECOG-ACRIN Microbiome Working Group
    • Published in top journals like Science
    • Developed predictive models for early cancer detection
    • Board-certified in internal medicine and medical oncology
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Bookimed Insights: Top Targeted therapy Specialists in Israel (2026)

Bookimed has coordinated 4 requests for Targeted therapy in Israel, collaborating with 9 top-rated specialists. The doctors in this table are selected based on their international credentials, clinical expertise, and patient outcomes. The 2026 ranking is formed using verified data from actual patient cases and current programs from our partner clinics.
RankDoctorexperienceGood Fit ForWhat Sets Them ApartClinic & LocationConsultation
#126 years of experienceComplex NET casesLeading NET specialist at Israel's top hospital – runs dedicated NET service and research lab. NIH-trained in endocrine tumor genetics and hereditary syndromes.
Israel
from $650
#221 years of experienceMicrobiome-modulating cancer therapyLeader in microbial modulation for cancer treatment – founded ECOG-ACRIN Microbiome Working Group. Trained at top US institutions including University of Pennsylvania and MD Anderson.
Israel
from $650

FAQ

These FAQs come from real patients seeking medical assistance through Bookimed. Answers are given by experienced medical coordinators and trusted clinic representatives.

How can I choose the best targeted therapy doctor in Israel?

Choosing the best targeted therapy doctor in Israel requires identifying specialists with international fellowship training and clinical trial leadership. Prioritize board-certified oncologists at JCI-accredited centers like Sourasky Medical Center. These experts often hold memberships in the European Society of Medical Oncology (ESMO).

  • International training: Top doctors like Prof. Ofer Merimsky trained at renowned centers like Institut Gustave Roussy.
  • Research leadership: Select doctors like Dr. David Sarid who act as principal investigators for clinical trials.
  • Sub-specialization focus: Dr. Tamar Sapra focuses on gynecological cancers while Dr. Fredi Aviv specializes in oncohematology.
  • Genomic expertise: Dr. Ari Raphael pioneers national genomic medicine programs for precise treatment matching.

Bookimed Expert Insight: Data shows that choosing a doctor who moderates a Molecular Tumor Board, such as Dr. Ari Raphael, provides a significant advantage. These specialists don't just prescribe standard drugs but specialize in NGS interpretation. This ensures that targeted therapies are matched to specific genetic mutations rather than just the cancer type.

Patient Consensus: Patients note that working with doctors who run clinical trials often provides access to new protocols. They emphasize choosing specialists in Tel Aviv who participate in multidisciplinary boards for better-tailored treatments. Many felt more confident when their doctor had published research on their specific biomarker.

What makes Israeli oncologists specializing in targeted therapy different from those in other countries?

Israeli oncologists lead targeted therapy through rapid clinical translation of genomic research and unique diagnostic accuracy. Specialists like Dr. Ari Raphael and Prof. Ofer Merimsky integrate advanced liquid biopsies and molecular profiling into routine care. This precision approach often corrects initial diagnoses for up to 91% of complex international cases.

  • Molecular profiling: Experts use comprehensive genomic sequencing to identify specific treatable mutations in tumors.
  • Early drug access: Patients receive novel targeted medications through extensive phase I-III clinical trial programs.
  • Liquid biopsy leadership: Doctors monitor cancer markers via blood tests, reducing the need for invasive tissue biopsies.
  • Specialized fellowships: Leading oncologists hold advanced training from Memorial Sloan-Kettering, Royal Marsden, and Institut Gustave Roussy.

Bookimed Expert Insight: A distinct advantage in Israel is the integration of genomic medicine into national health initiatives. Dr. Ari Raphael leads the National Genomic Medicine Initiative, which allows for earlier access to T-cell sequencing and cfDNA monitoring. This structural collaboration means patients at clinics like Sourasky Medical Center receive experimental protocols years before they reach global markets.

Patient Consensus: Patients often mention being surprised by the depth of genomic testing available compared to their home countries. Many note that the innovative approach to rare mutations gave them treatment options they were previously told did not exist. They describe feeling a sense of relief when specialized protocols were tailored specifically to their genetic markers.

Can I get a second opinion from a targeted therapy specialist in Israel?

You can receive a second opinion from leading targeted therapy specialists in Israel through remote video consultations or in-person visits. Top oncologists at JCI-accredited centers like Sourasky Medical Center (Ichilov) and Assuta Medical Center provide genomic-guided treatment plans and access to early-phase clinical trials.

  • Specialized expertise: Prof. Ofer Merimsky at Sourasky Medical Center is a foremost expert in sarcoma and lung cancer.
  • Genomic medicine: Dr. Ari Raphael leads national genomic initiatives and specializes in liquid biopsies for precision oncology.
  • Consultation options: Specialists offer online reviews with fees ranging from $750 to $1,050 for senior experts.
  • Advanced therapies: Specialists like Dr. Pelles Sharon provide targeted treatments, SIRT therapy, and HIPEC for complex cases.

Bookimed Expert Insight: Israeli oncology centers often provide faster access to rare mutation analysis compared to many European facilities. Data shows that specialists like Dr. Ari Raphael at Sourasky Medical Center (Ichilov) integrate computational biology with clinical trials. This allows patients to receive personalized therapy recommendations based on the latest NGS genomic profiling techniques quickly.

Patient Consensus: Patients note that Israeli doctors often find treatment options or clinical trials missed by their local physicians. Many were surprised by how quickly they could arrange a video call to discuss rare mutations. Some Mentioned that sending pathology slides in advance is necessary to get the most out of the consultation.

Do targeted therapy doctors in Israel use personalized testing?

Targeted therapy doctors in Israel use personalized testing to match treatments to a tumor's specific genetic profile. Leading specialists utilize advanced genomic sequencing and molecular profiling to identify actionable mutations. This precision approach is standard at JCI-accredited centers like Sourasky Medical Center and Assuta Medical Center.

  • Genomic profiling: Specialists use Next-Generation Sequencing (NGS) to scan hundreds of cancer-related genes simultaneously.
  • Liquid biopsies: Experts like Dr. Ari Raphael use blood-based DNA tests to monitor treatment response.
  • Oncotesting: Doctors apply specific tests like Oncotype DX to determine if chemotherapy is necessary.
  • Targeted biomarkers: Oncologists test for PD-L1 and HER2 markers to predict immunotherapy and drug success.

Bookimed Expert Insight: Israel's leadership in genomic medicine is driven by specialists who also lead national research initiatives. For example, Dr. Ari Raphael at Sourasky Medical Center heads the Israeli National Genomic Medicine Initiative (PSIFAS). Patients often benefit from this integration, as doctors who participate in these national programs frequently serve as primary investigators for international clinical trials.

Patient Consensus: Patients note that while genetic testing is common, it is helpful to ask for comprehensive profiling early in the diagnosis. Many found that private facilities provide test results much faster than public options. They emphasize that's it's important to have a doctor who clearly explains how these test results change the treatment plan.

Will my doctor be able to communicate in English?

Patients seeking targeted therapy in Israel can expect seamless communication as English is the standard language for oncology consultations. Top specialists at facilities like Sourasky Medical Center undergo extensive training in the US, UK, and Europe, ensuring they are fluent in medical English.

  • International training: Many oncologists completed fellowships at institutions like Memorial Sloan-Kettering and Oxford.
  • Global board memberships: Surgeons actively participate in the American Society of Clinical Oncology (ASCO).
  • Academic leadership: Leading doctors publish research in English-language journals and lecture at international universities.
  • Research collaboration: Specialists lead global clinical trials, requiring constant English communication with international partners.

Bookimed Expert Insight: A notable pattern among Israel's top oncologists is their dual role as researchers and clinicians. For instance, Dr. Ari Raphael and Dr. David Sarid lead national genomic initiatives and clinical trials, which necessitates daily professional-level English. Patients often find that these doctors explain complex molecular results more clearly than general practitioners because of their academic backgrounds.

Patient Consensus: Patients note that consultations are typically conducted entirely in English without any language barriers. They describe feeling relieved that physicians speak directly to them rather than relying on translation apps or intermediaries. Many were surprised at how easily they could discuss intricate treatment details and side effects during their appointments.