Best Targeted therapy Targeted therapy in Israel: TOP 22 doctors

Dr. Pelles Sharon is a respected oncologist with extensive experience in targeted therapy and other advanced cancer treatments at Sourasky Medical Center.

• Specializes in targeted therapy for various cancers
• Contributed to clinical research on oncologic patients' attitudes towards trials
• Performs multiple advanced cancer treatments including SIRT therapy and HIPEC
• Works at Sourasky Medical Center (Ichilov), a leading Israeli hospital

Professor Ofer Merimsky leads the Soft Tissue and Bone Oncology unit at Sourasky Medical Center – Israel's top sarcoma specialist.

• 41 years of experience treating sarcomas with targeted therapies
• Fellowship in sarcoma at Institut Gustave Roussy, Paris
• ESMO faculty member for sarcoma research
• Published extensively on orthopedic oncology
• Former Chairman of Israel's Oncology Society

Dr. Sarid has published 30+ articles on cancer therapy and leads clinical trials in targeted treatments at Sourasky Medical Center.

• Specializes in chemotherapy, radiotherapy, and biological therapy for various cancers
• Over 38 years of experience as senior oncologist at Ichilov Medical Center
• Lecturer at Tel Aviv University – stays current with latest therapies
• Member of ESMO and ASCO – follows international treatment guidelines

Specialist in Oncological Gynecology and Radiotherapy at Sourasky Medical Center (Ichilov) with a focus on targeted therapy.

• Experienced in precision treatments for gynecological cancers
• Uses advanced radiotherapy techniques for targeted treatment
• Part of a leading oncology team at a top medical center

Dr. Einat Shacham‑Shmueli is a senior medical oncologist at the Gastrointestinal Clinic, Cancer Center, Sheba Medical Center. She treats cancers of the colon, stomach, and pancreas. She also manages metastatic disease. She uses precision diagnostics and biomarkers, systemic therapies, and radiotherapy. Care is provided within a multidisciplinary team.

She has authored more than 25 peer‑reviewed papers on GI oncology, tumor biology, and new treatments. Her work includes studies on stenting for malignant colonic obstruction. She serves as an investigator in international programs, including the NCI, the Radiation Therapy Oncology Group, and the Cancer Therapy Evaluation Program.

Education: MD, Tel Aviv University. Oncology residency, Tel Aviv Sourasky Medical Center. Advanced training in GI oncology, UCSF. Accreditations: Board certified in Oncology and Gastroenterology. Member, Israel Society of Oncology and Radiotherapy.

Dr. Yuri Goldes is a general surgeon with more than 20 years of clinical experience. He specializes in upper gastrointestinal and oncologic surgery. He is Deputy Director of the Department of General Surgery and Transplantation at Sheba Medical Center in Tel Aviv. He also leads the Upper GI Surgery Unit. He was named to Forbes Israel’s Best Doctors in 2025. He is ranked among Israel’s Best Gastrointestinal Surgeons by Forbes. In 2019, he received the Israeli Ministry of Health “Best Doctor of the Year” award.

He is an expert in advanced minimally invasive and robotic surgery. He treats diaphragmatic hernia, achalasia, GERD, and gallbladder disease. He also performs oncologic surgery for pancreatic, gastric, and esophageal cancers. He uses laparoscopic and robotic techniques.

He pioneered some of Israel’s first robotic oncologic resections of the stomach and pancreas. He is among a small group worldwide who perform minimally invasive Whipple procedures (pancreaticoduodenectomy) using advanced laparoscopy. He applies methods that improve outcomes and speed recovery. He provides personalized care.

Prof. Amit Tirosh leads the Neuroendocrine Tumors Service at Sheba Medical Center – a top specialist for complex NET cases.

• Expert in hereditary NET syndromes like MEN1 and VHL
• Head of Endocrine Oncology Bioinformatics Lab
• Advanced training at NIH in endocrine tumor genetics
• Published 40+ papers on NET treatments
• Main physician at Sheba's multidisciplinary VHL clinic

Dr. Raphael leads Israel's National Genomic Medicine Initiative and pioneers targeted therapy trials at Sourasky Medical Center.

• Specializes in thoracic malignancies and comprehensive genomic profiling
• Primary investigator for multiple immunotherapy clinical trials
• Molecular Tumor Board moderator for Israeli Lung Cancer Society
• Recipient of ESMO and IASLC research grants
• Develops liquid biopsy techniques for treatment monitoring

Dr. Ido Wolf leads the Medical Oncology Division at Sourasky Medical Center, specializing in targeted therapy.

• Head of Medical Oncology Division at a leading Israeli hospital
• Extensive experience in oncology and internal medicine
• Trained at Ben Gurion University of the Negev
• Background includes service in Army Medical Units

Director of Neuro-oncology Service at Sourasky Medical Center – Dr. Blumental brings decades of specialized expertise in neuro-oncology.

• Trained at Memorial Sloan-Kettering Cancer Center
• Senior neuro-oncologist since 1998
• Previously directed Neuro-oncology Service at Huntsman Cancer Institute

Dr. Dror Levin specializes in treating blood disorders and bone cancer in children at Sourasky Medical Center, one of Israel's leading hospitals.

• Director of children's hematology oncology department at Sourasky Medical Center
• Coordinates treatment of bone cancer (sarcoma) in children
• Trained at Rizzoli Orthopaedic Institute in Italy – a world leader
• Member of ISPHO (Israel Society of Pediatric Hematology Oncology)

Dr. Fredi Aviv brings 34 years of experience of focused expertise in oncohematology at Sourasky Medical Center.

• Specializes in targeted cancer treatments for blood disorders
• Works at Ichilov Clinic – a leading center for hematologic oncology
• Extensive experience with novel therapeutic approaches

Director of oncology hospitalization at Tel Aviv Medical Center, Ichilov – Dr. Stepfansky leads cancer care teams.

• 26 years of experience of experience in oncology and internal medicine
• Researcher in multiple clinical trial phases in oncology
• Specialized in internal medicine and oncology at Ichilov

Dr. Amir specializes in targeted therapy with Keytruda (Pembolizumab) for breast cancer, backed by over 30 presentations at scientific meetings.

• Awarded ESMO Breast Cancer Translational Research Award in 2013
• Fellowship-trained at Jules Bordet Institute and Emory University
• Member of European Society of Medical Oncology (ESMO)
• Published research recognized with ISCORT Best Paper of the Year Award twice

Professor Raanan Berger, MD PhD, is a medical oncologist and radiotherapist. He is Director of the Cancer Center at Sheba Medical Center and heads its clinical research unit. He was listed in Forbes Israel’s “Best Doctors” (2025). He leads the genitourinary oncology program with a focus on prostate cancer. His care includes systemic therapy and radiotherapy in a multidisciplinary, patient-centered model.

He is board-certified in oncology. He earned his MD and PhD at Tel Aviv University and completed his clinical training at Sheba. He then completed a postdoctoral fellowship at Dana-Farber/Harvard, focusing on prostate cancer with Dr. Philip Kantoff and molecular oncology in Dr. William C. Hahn’s lab. He is a member of ESMO and ASCO. He has co-authored more than 20 peer-reviewed papers, including studies on outcomes in high- versus very high-risk prostate cancer and on BRCA1/2 in large cohorts.

Dr. Nir Kleinmann, MD, directs the Endourology and Kidney Stones Unit at Sheba Medical Center. He is an expert in minimally invasive urology and urologic oncology. His focus is the kidney and upper urinary tract. He was named among Israel’s Best Doctors for 2025–2026 by Forbes and ResultMed.

He is a pioneer of kidney‑sparing laser surgery. He uses a dual‑laser system with neodymium and holmium for complex tumors. His expertise includes UTUC, kidney and prostate cancer, kidney stones, and BPH.

His research includes the OLYMPUS trial on chemoablation for UTUC. He has more than 60 publications.

He is an Israeli board‑certified urologist. He is a Fellow of the American Endourology Society and a member of the Israeli Urological Association and the EAU. He completed fellowships in Endourology and Minimally Invasive Surgery at Thomas Jefferson University. He also completed a fellowship in Kidney Cancer Research at McMaster University.

Professor Jair Bar, MD, PhD, is a thoracic oncologist and Deputy Director of the Cancer Center at Sheba Medical Center. He leads the Thoracic Oncology Unit. He treats lung cancer, including advanced non-small cell cases. His care includes medical oncology, radiotherapy, immunotherapy, and targeted therapy.

He runs a translational research lab focused on resistance to immunotherapy. He has published on exhaled-breath cancer metabolism and on angiogenesis inhibition in lung cancer.

He has chaired the Israel Lung Cancer Group since 2003. He is a member of the Israel Society of Clinical Oncology and Radiotherapy, the American Society of Clinical Oncology, and the American Association for Cancer Research. He is board-certified in Medical Oncology and Radiotherapy Oncology. He is a Senior Lecturer at Tel Aviv University.

Chief Physician of the Oncology Center at Assuta Medical Center – leading expert in targeted therapy.

• Specializes in precision oncology treatments
• Extensive experience with personalized cancer therapies
• Works at one of Israel's top cancer centers

Dr. Eytan Aharon Ben‑Ami, MD, is a Senior Physician in the Sarcoma and Bone Oncology Service at Sheba Medical Center. He heads the Oncology Division and the Early-Phase Clinical Trials Unit. He founded the Sheba Clinical Research Organization. He is an academic affiliate at Tel Aviv University.

He specializes in sarcomas and primary bone tumors, including soft tissue sarcoma, liposarcoma, leiomyosarcoma, and osteosarcoma. He leads Phase I trials in targeted therapy and immunotherapy. He designs personalized treatment plans for rare cancers. He also develops patient-centered programs, including pilots in advanced immunotherapy delivery.

He completed a fellowship in Sarcoma and Bone Oncology at the Dana-Farber Cancer Institute/Harvard Cancer Center. He has authored more than 40 publications on early detection, molecular and viral mechanisms, and new cancer therapies.