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Best Targeted therapy doctors in Israel: TOP 22 doctors

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Israel

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Pelles Sharon

  • 23 years of experience
  • Location: Israel, Tel Aviv
  • Dr. Pelles Sharon is a respected oncologist with extensive experience in targeted therapy and other advanced cancer treatments at Sourasky Medical Center.

    • Specializes in targeted therapy for various cancers
    • Contributed to clinical research on oncologic patients' attitudes towards trials
    • Performs multiple advanced cancer treatments including SIRT therapy and HIPEC
    • Works at Sourasky Medical Center (Ichilov), a leading Israeli hospital
  • Read more
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Ofer Merimsky

  • 5 Excellent 7 reviews
  • 41 years of experience
  • accreditations:
  • Location: Israel, Tel Aviv
  • Professor Ofer Merimsky leads the Soft Tissue and Bone Oncology unit at Sourasky Medical Center – Israel's top sarcoma specialist.

    • 41 years of experience treating sarcomas with targeted therapies
    • Fellowship in sarcoma at Institut Gustave Roussy, Paris
    • ESMO faculty member for sarcoma research
    • Published extensively on orthopedic oncology
    • Former Chairman of Israel's Oncology Society
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David Sarid

  • 5 Excellent 1 review
  • 38 years of experience
  • accreditations:
  • Location: Israel, Tel Aviv
  • Dr. Sarid has published 30+ articles on cancer therapy and leads clinical trials in targeted treatments at Sourasky Medical Center.

    • Specializes in chemotherapy, radiotherapy, and biological therapy for various cancers
    • Over 38 years of experience as senior oncologist at Ichilov Medical Center
    • Lecturer at Tel Aviv University – stays current with latest therapies
    • Member of ESMO and ASCO – follows international treatment guidelines
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Tamar Sapra

  • 39 years of experience
  • Location: Israel, Tel Aviv
  • Specialist in Oncological Gynecology and Radiotherapy at Sourasky Medical Center (Ichilov) with a focus on targeted therapy.

    • Experienced in precision treatments for gynecological cancers
    • Uses advanced radiotherapy techniques for targeted treatment
    • Part of a leading oncology team at a top medical center
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Einat Shacham Shmueli

  • 26 years of experience
  • Location: Israel, Ramat Gan
  • Dr. Einat Shacham‑Shmueli is a senior medical oncologist at the Gastrointestinal Clinic, Cancer Center, Sheba Medical Center. She treats cancers of the colon, stomach, and pancreas. She also manages metastatic disease. She uses precision diagnostics and biomarkers, systemic therapies, and radiotherapy. Care is provided within a multidisciplinary team.

    She has authored more than 25 peer‑reviewed papers on GI oncology, tumor biology, and new treatments. Her work includes studies on stenting for malignant colonic obstruction. She serves as an investigator in international programs, including the NCI, the Radiation Therapy Oncology Group, and the Cancer Therapy Evaluation Program.

    Education: MD, Tel Aviv University. Oncology residency, Tel Aviv Sourasky Medical Center. Advanced training in GI oncology, UCSF. Accreditations: Board certified in Oncology and Gastroenterology. Member, Israel Society of Oncology and Radiotherapy.

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Yuri Goldes

  • 28 years of experience
  • Location: Israel, Ramat Gan
  • Dr. Yuri Goldes is a general surgeon with more than 20 years of clinical experience. He specializes in upper gastrointestinal and oncologic surgery. He is Deputy Director of the Department of General Surgery and Transplantation at Sheba Medical Center in Tel Aviv. He also leads the Upper GI Surgery Unit. He was named to Forbes Israel’s Best Doctors in 2025. He is ranked among Israel’s Best Gastrointestinal Surgeons by Forbes. In 2019, he received the Israeli Ministry of Health “Best Doctor of the Year” award.

    He is an expert in advanced minimally invasive and robotic surgery. He treats diaphragmatic hernia, achalasia, GERD, and gallbladder disease. He also performs oncologic surgery for pancreatic, gastric, and esophageal cancers. He uses laparoscopic and robotic techniques.

    He pioneered some of Israel’s first robotic oncologic resections of the stomach and pancreas. He is among a small group worldwide who perform minimally invasive Whipple procedures (pancreaticoduodenectomy) using advanced laparoscopy. He applies methods that improve outcomes and speed recovery. He provides personalized care.

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Amit Tirosh

  • 26 years of experience
  • Location: Israel, Ramat Gan
  • Prof. Amit Tirosh leads the Neuroendocrine Tumors Service at Sheba Medical Center – a top specialist for complex NET cases.

    • Expert in hereditary NET syndromes like MEN1 and VHL
    • Head of Endocrine Oncology Bioinformatics Lab
    • Advanced training at NIH in endocrine tumor genetics
    • Published 40+ papers on NET treatments
    • Main physician at Sheba's multidisciplinary VHL clinic
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Ari Raphael

  • 29 years of experience
  • accreditations:
  • Location: Israel, Tel Aviv
  • Dr. Raphael leads Israel's National Genomic Medicine Initiative and pioneers targeted therapy trials at Sourasky Medical Center.

    • Specializes in thoracic malignancies and comprehensive genomic profiling
    • Primary investigator for multiple immunotherapy clinical trials
    • Molecular Tumor Board moderator for Israeli Lung Cancer Society
    • Recipient of ESMO and IASLC research grants
    • Develops liquid biopsy techniques for treatment monitoring
  • Read more
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Ido Wolf

  • 34 years of experience
  • accreditations:
  • Location: Israel, Tel Aviv
  • Dr. Ido Wolf leads the Medical Oncology Division at Sourasky Medical Center, specializing in targeted therapy.

    • Head of Medical Oncology Division at a leading Israeli hospital
    • Extensive experience in oncology and internal medicine
    • Trained at Ben Gurion University of the Negev
    • Background includes service in Army Medical Units
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Dvora Blumental

  • 30 years of experience
  • Location: Israel, Tel Aviv
  • Director of Neuro-oncology Service at Sourasky Medical Center – Dr. Blumental brings decades of specialized expertise in neuro-oncology.

    • Trained at Memorial Sloan-Kettering Cancer Center
    • Senior neuro-oncologist since 1998
    • Previously directed Neuro-oncology Service at Huntsman Cancer Institute
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Fredi Aviv

  • 34 years of experience
  • Location: Israel, Tel Aviv
  • Dr. Fredi Aviv brings 34 years of experience of focused expertise in oncohematology at Sourasky Medical Center.

    • Specializes in targeted cancer treatments for blood disorders
    • Works at Ichilov Clinic – a leading center for hematologic oncology
    • Extensive experience with novel therapeutic approaches
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Dror Levin

  • 5 Excellent 2 reviews
  • 41 years of experience
  • Location: Israel, Tel Aviv
  • Dr. Dror Levin specializes in treating blood disorders and bone cancer in children at Sourasky Medical Center, one of Israel's leading hospitals.

    • Director of children's hematology oncology department at Sourasky Medical Center
    • Coordinates treatment of bone cancer (sarcoma) in children
    • Trained at Rizzoli Orthopaedic Institute in Italy – a world leader
    • Member of ISPHO (Israel Society of Pediatric Hematology Oncology)
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Irina Stepfansky

  • 26 years of experience
  • Location: Israel, Tel Aviv
  • Director of oncology hospitalization at Tel Aviv Medical Center, Ichilov – Dr. Stepfansky leads cancer care teams.

    • 26 years of experience of experience in oncology and internal medicine
    • Researcher in multiple clinical trial phases in oncology
    • Specialized in internal medicine and oncology at Ichilov
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Sonnenblick Amir

  • 19 years of experience
  • Location: Israel, Tel Aviv
  • Dr. Amir specializes in targeted therapy with Keytruda (Pembolizumab) for breast cancer, backed by over 30 presentations at scientific meetings.

    • Awarded ESMO Breast Cancer Translational Research Award in 2013
    • Fellowship-trained at Jules Bordet Institute and Emory University
    • Member of European Society of Medical Oncology (ESMO)
    • Published research recognized with ISCORT Best Paper of the Year Award twice
  • Read more
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Raanan Berger

  • 27 years of experience
  • Location: Israel, Ramat Gan
  • Professor Raanan Berger, MD PhD, is a medical oncologist and radiotherapist. He is Director of the Cancer Center at Sheba Medical Center and heads its clinical research unit. He was listed in Forbes Israel’s “Best Doctors” (2025). He leads the genitourinary oncology program with a focus on prostate cancer. His care includes systemic therapy and radiotherapy in a multidisciplinary, patient-centered model.

    He is board-certified in oncology. He earned his MD and PhD at Tel Aviv University and completed his clinical training at Sheba. He then completed a postdoctoral fellowship at Dana-Farber/Harvard, focusing on prostate cancer with Dr. Philip Kantoff and molecular oncology in Dr. William C. Hahn’s lab. He is a member of ESMO and ASCO. He has co-authored more than 20 peer-reviewed papers, including studies on outcomes in high- versus very high-risk prostate cancer and on BRCA1/2 in large cohorts.

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Nir Kleinmann

  • 25 years of experience
  • Location: Israel, Ramat Gan
  • Dr. Nir Kleinmann, MD, directs the Endourology and Kidney Stones Unit at Sheba Medical Center. He is an expert in minimally invasive urology and urologic oncology. His focus is the kidney and upper urinary tract. He was named among Israel’s Best Doctors for 2025–2026 by Forbes and ResultMed.

    He is a pioneer of kidney‑sparing laser surgery. He uses a dual‑laser system with neodymium and holmium for complex tumors. His expertise includes UTUC, kidney and prostate cancer, kidney stones, and BPH.

    His research includes the OLYMPUS trial on chemoablation for UTUC. He has more than 60 publications.

    He is an Israeli board‑certified urologist. He is a Fellow of the American Endourology Society and a member of the Israeli Urological Association and the EAU. He completed fellowships in Endourology and Minimally Invasive Surgery at Thomas Jefferson University. He also completed a fellowship in Kidney Cancer Research at McMaster University.

  • Read more
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Jair Bar

  • 35 years of experience
  • Location: Israel, Ramat Gan
  • Professor Jair Bar, MD, PhD, is a thoracic oncologist and Deputy Director of the Cancer Center at Sheba Medical Center. He leads the Thoracic Oncology Unit. He treats lung cancer, including advanced non-small cell cases. His care includes medical oncology, radiotherapy, immunotherapy, and targeted therapy.

    He runs a translational research lab focused on resistance to immunotherapy. He has published on exhaled-breath cancer metabolism and on angiogenesis inhibition in lung cancer.

    He has chaired the Israel Lung Cancer Group since 2003. He is a member of the Israel Society of Clinical Oncology and Radiotherapy, the American Society of Clinical Oncology, and the American Association for Cancer Research. He is board-certified in Medical Oncology and Radiotherapy Oncology. He is a Senior Lecturer at Tel Aviv University.

  • Read more
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Ella Tepper

  • Location: Israel, Tel Aviv
  • Chief Physician of the Oncology Center at Assuta Medical Center – leading expert in targeted therapy.

    • Specializes in precision oncology treatments
    • Extensive experience with personalized cancer therapies
    • Works at one of Israel's top cancer centers
  • Read more
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Beni Boursi

  • 21 years of experience
  • Location: Israel, Ramat Gan
  • Prof. Ben Boursi specializes in gastrointestinal oncology and microbiome research, pioneering innovative cancer therapies at Sheba Medical Center.

    • Trained in gastrointestinal oncology at the University of Pennsylvania
    • Founder of the ECOG-ACRIN Microbiome Working Group
    • Published in top journals like Science
    • Developed predictive models for early cancer detection
    • Board-certified in internal medicine and medical oncology
  • Read more
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Choosing the Right Doctor and Clinic: Insider Tips

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Bookimed Insights: Top Targeted therapy Specialists in Israel (2026)

Bookimed has coordinated 4 requests for Targeted therapy in Israel, collaborating with 22 top-rated specialists. The doctors in this table are selected based on their international credentials, clinical expertise, and patient outcomes. The 2026 ranking is formed using verified data from actual patient cases and current programs from our partner clinics.
RankDoctorexperienceGood Fit ForWhat Sets Them ApartClinic & LocationConsultation
#123 years of experienceAdvanced cancer targeted therapySpecializes in targeted cancer therapies with research contributions to clinical trials. Performs multiple advanced treatments at Israel's leading medical center.
Israel
from $825
#241 years of experienceSoft tissue sarcomaIsrael's foremost sarcoma expert – leads Sourasky's specialty unit and serves on ESMO's sarcoma faculty. Trained at Institut Gustave Roussy, the world's oldest cancer center.
Israel
from $950
#338 years of experienceComplex metastatic cancersPrincipal investigator in clinical trials for cutting-edge therapies – offers access to emerging treatments. Lectured at Tel Aviv University and published 30+ oncology papers.
Israel
Price on request
#439 years of experienceGynecological cancer targeted therapyFocuses on precision treatments for gynecological cancers. Part of a leading oncology team at Sourasky Medical Center.
Israel
Price on request
#526 years of experienceComplex NET casesLeading NET specialist at Israel's top hospital – runs dedicated NET service and research lab. NIH-trained in endocrine tumor genetics and hereditary syndromes.
Israel
from $650
#629 years of experienceGenomic-guided cancer therapyPioneers Israel's national genomic medicine program with focus on liquid biopsies. ESMO/IASLC member leading immunotherapy trials and NGS interpretation clinics.
Israel
from $750
#734 years of experienceTargeted cancer therapiesLeads oncology division at top Israeli hospital with specialized training in targeted therapies. Combines academic expertise with military medical experience.
Israel
Price on request
#830 years of experienceNeuro-oncology casesSpecializes exclusively in neuro-oncology with leadership roles at top cancer centers. Trained at Memorial Sloan-Kettering.
Israel
from $1,050
#934 years of experienceHematologic malignanciesSenior hematologic oncology specialist at one of Israel's top medical centers. Focuses exclusively on blood cancers with 3+ decades of targeted therapy experience.
Israel
Price on request
#1041 years of experiencePediatric sarcoma treatmentSpecializes in childhood bone cancer – trained at Italy's renowned Rizzoli Orthopaedic Institute. Heads pediatric hematology oncology at Sourasky.
Israel
Price on request

FAQ

These FAQs come from real patients seeking medical assistance through Bookimed. Answers are given by experienced medical coordinators and trusted clinic representatives.

How can I choose the best targeted therapy doctor in Israel?

Choosing the best targeted therapy doctor in Israel requires identifying specialists with international fellowship training and clinical trial leadership. Prioritize board-certified oncologists at JCI-accredited centers like Sourasky Medical Center. These experts often hold memberships in the European Society of Medical Oncology (ESMO).

  • International training: Top doctors like Prof. Ofer Merimsky trained at renowned centers like Institut Gustave Roussy.
  • Research leadership: Select doctors like Dr. David Sarid who act as principal investigators for clinical trials.
  • Sub-specialization focus: Dr. Tamar Sapra focuses on gynecological cancers while Dr. Fredi Aviv specializes in oncohematology.
  • Genomic expertise: Dr. Ari Raphael pioneers national genomic medicine programs for precise treatment matching.

Bookimed Expert Insight: Data shows that choosing a doctor who moderates a Molecular Tumor Board, such as Dr. Ari Raphael, provides a significant advantage. These specialists don't just prescribe standard drugs but specialize in NGS interpretation. This ensures that targeted therapies are matched to specific genetic mutations rather than just the cancer type.

Patient Consensus: Patients note that working with doctors who run clinical trials often provides access to new protocols. They emphasize choosing specialists in Tel Aviv who participate in multidisciplinary boards for better-tailored treatments. Many felt more confident when their doctor had published research on their specific biomarker.

What makes Israeli oncologists specializing in targeted therapy different from those in other countries?

Israeli oncologists lead targeted therapy through rapid clinical translation of genomic research and unique diagnostic accuracy. Specialists like Dr. Ari Raphael and Prof. Ofer Merimsky integrate advanced liquid biopsies and molecular profiling into routine care. This precision approach often corrects initial diagnoses for up to 91% of complex international cases.

  • Molecular profiling: Experts use comprehensive genomic sequencing to identify specific treatable mutations in tumors.
  • Early drug access: Patients receive novel targeted medications through extensive phase I-III clinical trial programs.
  • Liquid biopsy leadership: Doctors monitor cancer markers via blood tests, reducing the need for invasive tissue biopsies.
  • Specialized fellowships: Leading oncologists hold advanced training from Memorial Sloan-Kettering, Royal Marsden, and Institut Gustave Roussy.

Bookimed Expert Insight: A distinct advantage in Israel is the integration of genomic medicine into national health initiatives. Dr. Ari Raphael leads the National Genomic Medicine Initiative, which allows for earlier access to T-cell sequencing and cfDNA monitoring. This structural collaboration means patients at clinics like Sourasky Medical Center receive experimental protocols years before they reach global markets.

Patient Consensus: Patients often mention being surprised by the depth of genomic testing available compared to their home countries. Many note that the innovative approach to rare mutations gave them treatment options they were previously told did not exist. They describe feeling a sense of relief when specialized protocols were tailored specifically to their genetic markers.

Can I get a second opinion from a targeted therapy specialist in Israel?

You can receive a second opinion from leading targeted therapy specialists in Israel through remote video consultations or in-person visits. Top oncologists at JCI-accredited centers like Sourasky Medical Center (Ichilov) and Assuta Medical Center provide genomic-guided treatment plans and access to early-phase clinical trials.

  • Specialized expertise: Prof. Ofer Merimsky at Sourasky Medical Center is a foremost expert in sarcoma and lung cancer.
  • Genomic medicine: Dr. Ari Raphael leads national genomic initiatives and specializes in liquid biopsies for precision oncology.
  • Consultation options: Specialists offer online reviews with fees ranging from $750 to $1,050 for senior experts.
  • Advanced therapies: Specialists like Dr. Pelles Sharon provide targeted treatments, SIRT therapy, and HIPEC for complex cases.

Bookimed Expert Insight: Israeli oncology centers often provide faster access to rare mutation analysis compared to many European facilities. Data shows that specialists like Dr. Ari Raphael at Sourasky Medical Center (Ichilov) integrate computational biology with clinical trials. This allows patients to receive personalized therapy recommendations based on the latest NGS genomic profiling techniques quickly.

Patient Consensus: Patients note that Israeli doctors often find treatment options or clinical trials missed by their local physicians. Many were surprised by how quickly they could arrange a video call to discuss rare mutations. Some Mentioned that sending pathology slides in advance is necessary to get the most out of the consultation.

Do targeted therapy doctors in Israel use personalized testing?

Targeted therapy doctors in Israel use personalized testing to match treatments to a tumor's specific genetic profile. Leading specialists utilize advanced genomic sequencing and molecular profiling to identify actionable mutations. This precision approach is standard at JCI-accredited centers like Sourasky Medical Center and Assuta Medical Center.

  • Genomic profiling: Specialists use Next-Generation Sequencing (NGS) to scan hundreds of cancer-related genes simultaneously.
  • Liquid biopsies: Experts like Dr. Ari Raphael use blood-based DNA tests to monitor treatment response.
  • Oncotesting: Doctors apply specific tests like Oncotype DX to determine if chemotherapy is necessary.
  • Targeted biomarkers: Oncologists test for PD-L1 and HER2 markers to predict immunotherapy and drug success.

Bookimed Expert Insight: Israel's leadership in genomic medicine is driven by specialists who also lead national research initiatives. For example, Dr. Ari Raphael at Sourasky Medical Center heads the Israeli National Genomic Medicine Initiative (PSIFAS). Patients often benefit from this integration, as doctors who participate in these national programs frequently serve as primary investigators for international clinical trials.

Patient Consensus: Patients note that while genetic testing is common, it is helpful to ask for comprehensive profiling early in the diagnosis. Many found that private facilities provide test results much faster than public options. They emphasize that's it's important to have a doctor who clearly explains how these test results change the treatment plan.

Will my doctor be able to communicate in English?

Patients seeking targeted therapy in Israel can expect seamless communication as English is the standard language for oncology consultations. Top specialists at facilities like Sourasky Medical Center undergo extensive training in the US, UK, and Europe, ensuring they are fluent in medical English.

  • International training: Many oncologists completed fellowships at institutions like Memorial Sloan-Kettering and Oxford.
  • Global board memberships: Surgeons actively participate in the American Society of Clinical Oncology (ASCO).
  • Academic leadership: Leading doctors publish research in English-language journals and lecture at international universities.
  • Research collaboration: Specialists lead global clinical trials, requiring constant English communication with international partners.

Bookimed Expert Insight: A notable pattern among Israel's top oncologists is their dual role as researchers and clinicians. For instance, Dr. Ari Raphael and Dr. David Sarid lead national genomic initiatives and clinical trials, which necessitates daily professional-level English. Patients often find that these doctors explain complex molecular results more clearly than general practitioners because of their academic backgrounds.

Patient Consensus: Patients note that consultations are typically conducted entirely in English without any language barriers. They describe feeling relieved that physicians speak directly to them rather than relying on translation apps or intermediaries. Many were surprised at how easily they could discuss intricate treatment details and side effects during their appointments.