Best Cleft Lip or Palate Repair doctors: TOP 102 doctors

Dr. has a Master's Degree in Hospital and Health Institution Management and has worked in many institutions, such as the Ministry of Health Haseki Training and Research Hospital and Bezmialem University. He has attended many international conferences and won awards, and has research papers published. His fields of expertise include Nose Aesthetics, Cochlear Implant, Hearing Losses, Ear Infections, Balance Disorders, Nasal Allergies, Nasal Polyposis, Cancer Surgery, Facial Plastic Surgery, Voice Disorders, Thyroid Nodules, Sinusitis, Endoscopic Sinus Surgery, Tonsil and Adenoid Diseases and Snoring, Sleep Apnea Surgery. He has had international experiences in the US at Johns Hopkins University, Harvard University, Harvard Medical School, Boston Children's Hospital, Tufts University, and Cleveland Clinic.

Dr. Kadriye İpek Uzunoglu is among the best cosmetic and plastic surgeons serving patients at Memorial Şişli Hospital in Istanbul, Turkey. Also, she is one of the top-rated revision rhinoplasty surgeons. 

• Since 2025 –Aesthetic, plastic and reconstructive surgeon in Memorial Şişli Hospital in Istanbul, Turkey
• 2024 -2025  Aesthetic, plastic and reconstructive surgeon in Baypark Hospital in Turkey
• 2024 - 2024  Aesthetic, plastic and reconstructive surgeon in Bagcılar Legal Training and Research Hospital in Turkey
• 2021 - 2024  Aesthetic, plastic and reconstructive surgeon in Konya City Hospital in Turkey
• 2018 - 2021  Aesthetic, plastic and reconstructive surgeon in Konya Legal Training and Research Hospital in Turkey
• 2017 - 2018  Aesthetic, plastic and reconstructive surgeon in Sivas City Hospital in Turkey
• 2011 - 2017 Aesthetic, plastic and reconstructive surgeon in Sivas Republıc University  Hospital in Turkey
• 2011 - 2011 Emergency Dr in Resadiye  Hospital  University  Hospital in Turkey
• 2010 - 2011 Emergency Dr in Tokat  Hospital  University  Hospital in Turkey

Education

• 2011 - 2017  The Faculty of Medicine, Plastic, Reconstructive, and Aesthetic Surgery at Sivas Republic  University , Specialization Training
• 2015 - 2015   University of Alabama at Birmingham, Department of Surgery, Division of Plastic Surgery (Observer, August-November 2015)
• 2003 - 2010   The Faculty of Medicine at Samsun  University, Medical Doctor Training.

Additional training

• Cumhuriyet University Laboratory Animal Usage Certificate Course
•  
•  
• • TPRECD 45th National Congress
• • TPRECD 8th Rhinoplasty Course
• • TPRECD 1st Facial Aesthetics
• • TPRECD Winter Symposium 2016,
• • EPCD 20th National Congress
• • RMCD XIXth Basic Microsurgery Course
• • TPRCD 9th Plastic Surgery School
• • EPCD 28th National Congress
• • TPRECD XIIIth Rhinoplasty and VIth Facial Aesthetics Course

Membership in organizations

• • Turkish Medical Association
• • Turkish Plastic and Aesthetic Surgery Association
• • Turkish Aesthetic Surgery Association
• • Women Physicians Education Support Foundation

Prof. Dr. Tayfun Apuhan is a specialist in ENT and Head & Neck Surgery. He is known for his skill in treating ear infections, repairing the tympanic membrane, and performing rhinoplasty and septorhinoplasty. He also has experience in adenoidectomy, tonsillectomy, sleep apnea surgery, vocal cord microsurgery, and head and neck tumor surgery. Dr. Apuhan founded the ENT and Head & Neck Surgery Department at Özel A Plus Hisar Intercontinental Hospital.

Dr. Apuhan earned his medical degree from İnönü University. He completed further training at Abant Izzet Baysal University, University Medical Center Hamburg-Eppendorf, Gazi University, and The Ohio State University Comprehensive Cancer Center. He has published over 200 scientific articles. He has also served as a session chair and editor at international conferences and journals. Dr. Apuhan currently leads the audiometry program at Doğuş University.

Assoc. Prof. Selman Sarica, M.D., is a board-certified otorhinolaryngologist. He specializes in otology, pediatric ENT, snoring surgery, head and neck tumors, laryngology, functional nasal surgery, endoscopic sinus surgery, thyroid surgery, and salivary gland surgery. He received his medical degree from Istanbul University Cerrahpaşa Faculty of Medicine. He completed his ENT residency at Kahramanmaraş Sütçü İmam University, where he now serves as an Associate Professor.

Dr. Sarica has performed hundreds of advanced ear, nose, and throat surgeries. His experience includes complex head and neck tumor resections and endoscopic procedures. He is known for his research in voice analysis and has published several peer-reviewed articles. Dr. Sarica holds national accreditation and is respected for his clinical and academic work in ENT.

Dr. Melikgazi Ozturk is a specialist in Plastic, Reconstructive, and Aesthetic Surgery. He currently practices at Memorial Şişli Hospital. He has worked as a specialist at several leading hospitals, including Şişli Hamidiye Etfal Training and Research Hospital, Afyonkarahisar State Hospital, Düzce Atatürk State Hospital, and Kayseri City Training and Research Hospital.

Dr. Ozturk completed his specialist training at Erciyes University Faculty of Medicine, where he also served as a research assistant from 2018 to 2023. He received his medical degree from Hacettepe University Faculty of Medicine. He has also worked as a general practitioner at Çorum Sungurlu State Hospital. Dr. Ozturk’s background combines strong clinical experience with academic research in plastic and reconstructive surgery.

Dr. Süleyman Hilmi Yilmaz, M.D., is an Assistant Professor in otorhinolaryngology. He specializes in nasal congestion, nasal deformity, polyposis, lacrimal gland obstructions, head and neck tumors, and thyroid cancer. He also performs advanced ENT surgeries, including endoscopic sinus surgery and septal correction.

He graduated from Kocaeli University Faculty of Medicine in 2006. He completed his residency at Istanbul Kartal Training and Research Hospital in 2013. Dr. Yilmaz has published many articles in both local and international journals. He is a member of the Turkish Otorhinolaryngology Head and Neck Surgery Association, the Istanbul ENT-BCC Specialists Association, and the Skull Base Association.

EXPERIENCE

2019 - Currently, Istanbul/Istanbul/Turkey

MEMORIAL BAHÇELIEVLER HOSPITAL

Plastic, Reconstructive and Aesthetic Surgery Specialist

2015 - Currently, Istanbul/Istanbul/Turkey

BAHÇEŞEHİR UNIVERSITY FACULTY OF MEDICINE

Faculty Member

2009 - 2009, /ABD

JOHNS HOPKINS UNIVERSITY

Faculty Member

2008 - 2008, /Sweden

UPPSALA UNIVERSITY

Faculty Member

2000 - 2015, Kocaeli/Kocaeli/Turkey

KOCAELI UNIVERSITY FACULTY OF MEDICINE

Faculty Member

EDUCATION

2015

PROFESSOR

2009

ASSOCIATE PROFESSOR

1992 - 1999, Antalya/Turkey

MEDITERRANEAN UNIVERSITY FACULTY OF MEDICINE

Expertise Training

1985 - 1991, Ankara/Turkey

ANKARA UNIVERSITY FACULTY OF MEDICINE

Medical Doctor Training

SCIENTIFIC PUBLICATIONS

Over 170 scientific presentations and speeches at national and international scientific meetings

51 scientific articles, 33 of which are international

Author of 6 books and book chapters

3 TUBITAK projects

2 TUBITAK science incentive awards

Turkish Society of Plastic Reconstructive and Aesthetic Surgery Research Competition 2nd Prize

Abdominal fascial flaps to provide complete implant coverage in one-stage breast reconstruction: an autologous solution

Preoperative colour Doppler evaluation in the planning of gluteal perforator flaps

A new application to increase breast projection in free breast graft reduction mammoplasty

A new application for the repair of penile skin defect; anterior scrotal artery flap

Use of botulinum toxin for correction of asymmetric crying faces

A useful tool for W-plasty design in the excision of irregular lesions

PROFESSIONAL MEMBERSHIPS

Turkish Society of Plastic Reconstructive and Aesthetic Surgery

Aesthetic Plastic Surgery Association

International Society of Plastic Surgery (ISAPS)

Kocaeli Breast Diseases Research and Treatment Association

Turkish Medical Informatics Association

Interplast Turkey Association

Balkan Association of Plastic Reconstuctive Aesthetic. Surgery

The AO Foundation AO CMF

Op. Dr. Atilla H.

Plastic Surgeon

Education

Specialty Training

2010 - 2016
Ankara Numune Training and Research Hospital, Department of Plastic, Reconstructive, and Aesthetic Surgery

Undergraduate Education

1989 - 1995
Uludağ University Faculty of Medicine

Experience

2020 -
ClinicExpert - Plastic Surgery Specialist

Biography

Born in Cyprus, Plastic, Reconstructive, and Aesthetic Surgeon, Op. Dr. Atilla H. worked at Medical Park Bahçelievler Hospital for 3 years. He graduated from Uludağ University Faculty of Medicine in 1995 and completed his specialization at Ankara Numune Training and Research Hospital in 2001. He worked at Ankara Bayındır Hospital for 2 years and at İskenderun State Hospital for 14 years.

Certificates

2021 - Thread Lift - Face Lift Certificates (Belgium)

Dr. Md Caner Kaya is a board-certified plastic surgeon with over 15 years of experience. He practices at TWT Health Clinic in Istanbul. His main areas of expertise are body contouring, facial plastic surgery, and breast procedures. He performs rhinoplasty, facelifts, blepharoplasty, breast augmentation, and FUE hair transplantation.

Dr. Kaya has performed more than 10,000 surgeries. This shows his skill and dedication to patient satisfaction. He earned his medical degree from Bolu Abant İzzet Baysal University. He completed his specialization at Marmara University. Dr. Kaya is known for providing high-quality, personalized care in both aesthetic and reconstructive surgery.

Dr. Jordi Coromina Isern is a respected otolaryngologist with over 30 years of experience. He specializes in treating ENT diseases. He is skilled in advanced surgeries, including cochlear implants, septoplasty, tonsillectomy, tympanoplasty, and cleft lip or palate repair.

Dr. Coromina is known for introducing laser and Da Vinci robotic surgeries in ENT care. He has received the César Bertrán Award from the Spanish Society of Otolaryngology. He also received an award from the Catalan Society of Pulmonology for his clinical achievements.

He is a member of several leading medical societies. He completed his medical training with honors and gained international experience at institutions such as Mayo Clinic and Boston Children's Hospital.

Ivan Vadimovich Kononikhin – plastic surgeon at Vidnova clinic

Qualification

In 2012, he graduated from Zaporizhzhia State Medical University with a degree in "Medical Medicine". Then he completed an internship at the Department of Surgery and Proctology of the ZMAPE in the 9th City Hospital (Zaporizhzhya).

After completing his internship, he was referred to the Veselivska Central District Hospital, where he worked until 2019.

From 2016 to 2018, he worked in parallel at the Atlant Medical Center (Melitopol). During this time, he completed many training and practical courses, including laparoscopic and minimally invasive surgical interventions at the ZMAPO, endoscopic examination methods at the ZHMU.

Since 2015, he has been actively involved in aesthetic medicine, paying great attention to contouring and botulinum therapy. Every year he attends many practical and scientific conferences on surgery and aesthetic medicine.

In 2019, he received the second qualification category in the specialty "Surgery".

Work experience

Ivan Kononikhin performs about 400 operations annually. His medical experience amounts to 11 years of successful work and constant development.

Today, Ivan Vadymovych is a member of the Ukrainian Society of Aesthetic Plastic Surgeons.

List of operations and procedures

Ivan Kononikhin is a plastic surgeon with a broad profile. He performs a full range of plastic surgeries on the face and body.

• Breast augmentation
• Breast lift
• Breast lift with augmentation
• Gynecomastia
• Tummy tuck (abdominoplasty)
• Liposuction
• Blepharoplasty
• Facial lipofilling
• Otoplasty
• Correction of postoperative scars
• Botulinum therapy (Dysport injections)
• Contour plastic surgery with fillers
• Lip contouring (lip augmentation)

Prof. Ralf Buhl is world famous neurosurgeon with over 20 years of experience. Doctor Buhl heads the Neurosurgery Department at Solingen Klinikum. His reputation reaches China and the US where he provides neurosurgical lectures.

Specialty

Dr. Buhl specializes in non-invasive methods treatment of disc herniation, brain and spinal cord tumors. The doctor provides treatment of peripheral nervous system disorders and performs computer-assisted navigation microsurgeries.

Dr. Ralf Buhl has provided over 4,000 successful neurosurgeries. Among his patients are famous politicians, businessmen, musicians, actors. In 2015, a Hollywood star George Clooney had severe back pain and was treated by Professor Buhl.

Scientific activity

Dr. Buhl conducts scientific work and researches in intracranial cavernomas treatment, surgical treatment for brain metastases and other neurosurgery areas.

Рrofessor Buhl has cofound the Fund devoted to the study of brain tumors.

Curriculum Vitae

Name: Yasin Kulaksız
Date of Birth: November 20, 1992
Title: Specialist Doctor

Education

Doctarate (PhD)
Field: Ear, Nose, and Throat (ENT)
University: Bezmialem Vakıf University
Year: [Year of Completion]

Doctorate (PhD)
Field: Ear, Nose, and Throat (ENT)
University: Bezmialem Vakıf University

Skills

• Expertise in Rhinoplasty and ENT surgeries
• Patient assessment and care
• Surgical techniques and postoperative management
• [Additional relevant skills]

CURRICULUM VITAE

VOLKERT B. WREESMANN MD PhD

Consultant Otolaryngologist

Oncologic Head and Neck Surgeon

Thyroid and Parathyroid Surgeon

Facial Plastic Surgeon

Principal Positions

• Centro Medico Teknon, Barcelona, Spain

Chairman, Department of Otolaryngology-Head and Neck Surgery

July 1st 2024 – present

• Juaneda, Ciutadella Menorca, Spain

Consultant Otolaryngologist-Head and Neck Surgeon

January 2025 – present

• Avantmedic, Lleida, Spain

Consultant Otolaryngologist-Head and Neck Surgeon

July 1st 2024 – present

• Clinica Omega Zeta, Andorra

Consultant Otolaryngologist-Head and Neck Surgeon

March 1st 2022 – present

• University Hospitals Dorset NHS Foundation Trust

Consultant Otolaryngologist-Head and Neck Surgeon

August 1st 2021 – October 1st 2023

• Oxford University Hospitals NHS Foundation Trust

Honorary Consultant Otolaryngologist-Head and Neck Surgeon

May 1st 2021 – April 30th 2024

• Portsmouth Hospitals University NHS Trust, Portsmouth, UK

Consultant Otolaryngologist-Head and Neck Surgeon

July 18th 2016 – April 30th 2021

• Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK

Consultant Otolaryngologist-Head and Neck Surgeon

November 7th 2015 – May 31st 2016

• Heart of England NHS Trust, Birmingham, UK

Consultant Otolaryngologist-Head and Neck Surgeon

March 1st 2015 – October 31st 2015

• University Medical Center Utrecht, Netherlands

Consultant Otolaryngologist-Head and Neck Surgeon

November 1st 2013 – June 1st 2014

Memberships

• American Head and Neck Society – Member

Netherlands Academy of Otolaryngology - Member

Professional Licences

• United Kingdom

GMC Certification

Fully Registered Medical Practitioner with Specialist Registration with a License to Practice

Registered: 02/02/2015

GMC # 7499626

• United States of America

New York State Department of Health

New York State Education Department

Registered: July 2011

License# P80949

Physician

• Netherlands

Dutch Ministry of Health (BIG Registration)

BIG Registered: 22-06-2005

BIG #19063373601

Physician

Dutch Specialist Board (RGS)

RGS registered: 01-02-2011

RGS #1911979

Otolaryngology-Head and Neck Surgeon

• Spain

Collegi de Metges de Barcelona

COMB: 63638

• Andorra

Collegi de Metges d’Andorra

RPS: 03098

COMA: 876

Education

• Memorial Sloan-Kettering Cancer Center

Surgical Fellowship, Head and Neck Surgery

New York, New York, USA

August 1st 2011 - July 31st 2013

600 bed dedicated cancer center

Performed 1200 major oncologic head and neck resections in 2 years

• United States of America ECFMG Certification

United States Medical Licensing Examination (USMLE)

Certification: June 22nd, 2010

Scores: 

   Step I: 244/99 

   Step IIa-Clinical knowledge: 227/94

   Step IIb-Clinical Skills: PASSED

   Step III: 206/85

• Netherlands Cancer Institute

Surgical Fellowship, Head and Neck Surgery

Amsterdam, The Netherlands

February 1st 2011 - July 31st 2011

Specialized Head and Neck Cancer Surgery Department

200 bed hospital

• Amsterdam University Medical Center/Netherlands Cancer Institute

Residency Training, Otolaryngology-Head and Neck Surgery

Amsterdam, the Netherlands

February 1st 2006 – January 31st 2011

• University of Amsterdam School of Medicine

Medical Doctor (MD)

Amsterdam, the Netherlands

December 2002 - January 28th 2005

• University of Amsterdam

Doctor of Philosophy (PhD), Molecular Biology

Amsterdam, the Netherlands

Thesis title: Molecular-cytogenetic characterization of head and neck cancer

December 2nd, 2004

• Erasmus University School of Medicine

Doctoral Degree in Medicine

Rotterdam, the Netherlands

September 1994 - November 17th, 1998

Research Training

• Memorial Sloan-Kettering Cancer Center

Laboratory of Epithelial Cancer Biology, Head and Neck Service, Department of Surgery, New York, New York, USA

Research Fellowship in Molecular Oncology

Supervisors: Dr. Bhuvanesh Singh MD, PhD and Dr. Jatin P. Shah, MD, FACS

March 1st 1999 - September 30st 2002

• University of California San Francisco (UCSF)

Department of Otolaryngology-Head and Neck Surgery, San Francisco, California, USA

Post-doctoral Research Fellowship in Head and Neck Oncology

Supervisors: Dr. Steven Wang MD And Prof David Eisele MD

February 2005 - January 2006

Academic Activities

University of Amsterdam

Doctorate Examination Committee member

• September 17th, 2013 - PhD Candidate: Dr. I.J. Nixon (United Kingdom)
• October 17th 2014 - PhD Candidate: Dr. J. Pramana (Netherlands)
• November 17th 2015 - PhD candidate: Dr. H. van Monsjou (Netherlands)
• December 11th 2018 - PhD Candidate: Dr. Tihana Ibrahimpasic (United States)
• January 18th, 2021 - PhD Candidate: Dr. Laura Wang (Australia)
• June 2nd, 2021 - PhD Candidate: Dr. Caroline Verhagen (Netherlands)

Conference Faculty

• Advanced Laryngopharyngeal Cancer: Functional Preservation and Rehabilitation, Portsmouth, June 25th - 26th, 2020 (postponed due to COVID) - Chairman
• Functional Preservation and Rehabilitation after Treatment for Advanced Laryngeal Cancer, Portsmouth, March 14th - 15th, 2019 - Chairman
• Portsmouth Parathyroid Conference, Portsmouth, December 14th 2018 – Chairman

Editorial Roles

• European Journal of Surgical Oncology

Associate Editor

January 1st 2023 – present

• European Journal of Surgical Oncology

Guest Editor

March issue 2018, Volume 44, Issue 3, p275-378 - Special issue on thyroid cancer management

• Journal of Oral Pathology and Medicine

Guest Editor

November issue 2021, Volume 51, Issue 10 - Special issue on vascular malformations and tumors of the head and neck

• Scientific Journal Reviewer

Oral Oncology, European Journal of Surgical Oncology, Journal of Surgical Oncology, Head and Neck, International Journal of Cancer

• Scientific Project and Grant Reviewer

Netherlands: Dutch Cancer Society

France: Institute National du Cancer

Awards

• New York Head and Neck Society

Annual Meeting, New York, NY, March 2002

Title of study presented: “MUC1 is a target if 1q amplification and pertains a grave clinical prognosis in papillary thyroid cancer”

Invited Lectures

• European Society of Surgical Oncology meeting, Krakow, 2016
• Barcelona Society of Neurosurgery, Annual Meeting, Baqueira, Spain, February, 2017
• University of Edinburgh, Department of Otolaryngology Academic Conference, March 17th 2017
• Medilex: Performance of Medical Specialists, Zeist, Netherlands, November 9th 2017
• Medilex: Performance of Medical Specialists, Driebergen, Netherlands, October 11th 2017
• Wessex Head and Neck and Thyroid Network Education Day, May 3rd, 2017
• Portsmouth Parathyroid Conference, Portsmouth, UK, December 14th 2018
• Global Post-laryngectomy Rehabilitation Academy, Portsmouth, UK, March 14th 2019
• Health Care Quality Conference, Beverwijk, Netherlands, March 25th, 2019

Published Research Reports

• The growing precision of diagnostic pathways in thyroid nodule evaluation. 

Bekker J, Wreesmann VB. 

Eur J Surg Oncol. 2025 Jan;51(1):109374.

• Special issue: Management of vascular tumors and malformations of the head and neck. 

Oomen KPQ, Brennan PA, Wreesmann VB. 

J Oral Pathol Med. 2022 Nov;51(10):829.

• Angiosarcomas of the head and neck: Impact of large data analysis on clinical management.
•  
• Wreesmann VB, Oomen KP, Brennan PA.

J Oral Pathol Med. 2022 Nov;51(10):904-910.

• Current classification of vascular anomalies of the head and neck. 

Oomen KPQ, Wreesmann VB. 

J Oral Pathol Med. 2022 Nov;51(10):830-836.

• A novel classification of carotid body tumors.

Wreesmann VB, Nixon IJ. 

Eur. J. Surg. Oncol. May, 2021

• Management of the contralateral central neck in differentiated thyroid cancer: A contentious issue. 

Shaha AR, Tuttle RM, Wreesmann VB. 

Eur. J. Surg. Oncol. 2021 Apr;47(4):717-719.

• Improvement of oral cancer screening quality and reach: The promise of artificial intelligence.
•  
• Kar A, Wreesmann VB, Shwetha V, Thakur S, Rao VUS, Arakeri G, Brennan PA.

J Oral Pathol Med. 2020 Mar 11

• The risk-benefit ratio of chemoradiation treatment in head and neck squamous cell carcinoma: value of extranodal spread and margin status. 

Ammar M, Wreesmann VB. 

Journal of ENT Masterclass, Yearbook 2018, Volume 11, Nr. 1, December 1st, 2018

• Nasal obstruction secondary to an inverted midline supernumerary tooth. 

Jones L, Hilton JM, Heyman J, Viswanathan H, Wreesmann VB, Hayes SM. 

Ann R Coll Surg Engl. 2019 Jan;101(1)

• Fanconi anemia and homologous recombination gene variants are associated with functional DNA repair defects in vitro and poor outcome in patients with advanced head and neck squamous cell carcinoma. 

Verhagen CVM, Vossen DM, Borgmann K, Hageman F, Grénman R, Verwijs-Janssen M, Mout L, Kluin RJC, Nieuwland M, Severson TM, Velds A, Kerkhoven R, O'Connor MJ, van der Heijden M, van Velthuysen ML, Verheij M, Wreesmann VB, Wessels LFA, van den Brekel MWM, Vens C. 

Oncotarget. 2018 Apr 6;9(26):18198-18213.

• Complete nasal obstruction secondary to pacemaker insertion. 

Jones TL, Wreesmann VB, Nilssen E, Hilton J, Hayes SM. 

Ann R Coll Surg Engl. 2018 May;100(5)

• Optimization of the risk-benefit ratio of differentiated thyroid cancer treatment. 

Nasef HO, Nixon IJ, Wreesmann VB. Eur J Surg Oncol. 

2018 Mar;44(3):276-285. Review.

• The risk/benefit ratio of differentiated thyroid cancer treatment: Exploring treatment de-escalation. 

Wreesmann VB; on behalf of EJSO. 

Eur J Surg Oncol. 2018 Mar;44(3):275.

• Aggressive differentiated thyroid cancer. 

Janjua N, Wreesmann VB. 

Eur J Surg Oncol. 2018 Mar;44(3):367-377. Review.

• Role of extracapsular nodal spread and surgical margin status in defining high-risk head and neck squamous cell carcinoma and its treatment intensity. 

Wreesmann VB. 

International Journal of Head and Neck Surgery, April-June 2017; 8(2): 76-83.

• An International Multi-Institutional Validation of Age 55 Years as a Cutoff for Risk Stratification in the AJCC/UICC Staging System for Well-Differentiated Thyroid Cancer.              

Nixon IJ, Wang LY, Migliacci JC, Eskander A, Campbell MJ, Aniss A, Morris L, Vaisman F, Corbo R, Momesso D, Vaisman M, Carvalho A, Learoyd D, Leslie WD, Nason RW, Kuk D, Wreesmann V, Morris L, Palmer FL, Ganly I, Patel SG, Singh B, Tuttle RM, Shaha AR, Gönen M, Pathak KA, Shen WT, Sywak M, Kowalski L, Freeman J, Perrier N, Shah JP. 

Thyroid. 2016 Mar;26(3):373-80.

• Influence of extracapsular nodal spread extent on prognosis of oral squamous cell carcinoma. 
•  
• Wreesmann VB, Katabi N, Palmer FL, Montero PH, Migliacci JC, Gönen M, Carlson D, Ganly I, Shah JP, Ghossein R, Patel SG.

Head Neck. 2016 Apr;38 Suppl 1:E1192-9.

• Defining a Valid Age Cutoff in Staging of Well-Differentiated Thyroid Cancer. 

Nixon IJ, Kuk D, Wreesmann V, Morris L, Palmer FL, Ganly I, Patel SG, Singh B, Tuttle RM, Shaha AR, Gönen M, Shah JP. 

Ann Surg Oncol. 2015 Jul 28.

• Prognostic value of vascular invasion in well-differentiated papillary thyroid carcinoma.
•  
• Wreesmann VB, Nixon IJ, Rivera M, Katabi N, Palmer F, Ganly I, Shaha AR, Tuttle RM, Shah JP, Patel SG, Ghossein RA.

Thyroid. 2015 May;25(5):503-8.

• Head and neck squamous cell carcinoma in young patients.

van Monsjou HS, Wreesmann VB, van den Brekel MW, Balm AJ. 

Oral Oncol. 2013 Dec;49(12):1097-102.

• Oral and oropharyngeal squamous cell carcinomas in young patients: The Netherlands Cancer Institute experience. 

van Monsjou HS, M Lopez-Yurda, M. Hauptmann, Balm AJ, van den Brekel MM, Wreesmann VB. 

Head Neck. 2013 Jan;35(1):94-102.

• Oropharyngeal squamous cell carcinoma: a unique disease on the rise?

van Monsjou HS, Balm AJ, van den Brekel MM, Wreesmann VB. 

Oral Oncol. 2010 Nov;46(11):780-5.

• Closure of tracheoesophageal fistula with prefabricated revascularized bilaminar radial forearm free flap.

Wreesmann VB, Smeele LE, Hilgers FJ, Lohuis PJ. 

Head Neck. 2009 Jun;31(6):838-42.

• Clinical impact of molecular analysis on thyroid cancer management.

Wreesmann VB, Singh B. 

Surg Oncol Clin N Am. 2008 Jan;17(1):1-35.

Genetic abnormalities associated with chemoradiation resistance of head and neck squamous cell carcinoma. 

van den Broek GB, Wreesmann VB, van den Brekel MW, Rasch CR, Balm AJ, Rao PH. 

Clin Cancer Res. 2007 Aug 1;13(15 Pt 1):4386-91.

• Association of CD44 V3-containing isoforms with tumor cell growth, migration, matrix metalloproteinase expression, and lymph node metastasis in head and neck cancer.

Wang SJ, Wreesmann VB, Bourguignon LY. 

Head Neck. 2007 Jun;29(6):550-8.

• Downregulation of Fanconi anemia genes in sporadic head and neck squamous cell carcinoma.
•  
• Wreesmann VB, Estilo C, Eisele DW, Singh B, Wang SJ.

ORL J Otorhinolaryngol Relat Spec. 2007;69(4):218-25. Epub 2007 Apr 4.

• Patterns of expression of cell cycle/apoptosis genes along the spectrum of thyroid carcinoma progression.
•  
• Saltman B, Singh B, Hedvat CV, Wreesmann VB, Ghossein R.
•  
• Surgery. 2006 Dec;140(6):899-905; discussion 905-6.

• Repetitive endoscopic sinus surgery failure: a role for radical surgery?

Videler WJ, Wreesmann VB, van der Meulen FW, Knegt PP, Fokkens WJ. 

Otolaryngol Head Neck Surg. 2006 Apr;134(4):586-91.

• MUC1 plays a role in tumor maintenance in aggressive thyroid carcinomas.
•  
• Patel KN, Maghami E, Wreesmann VB, Shaha AR, Shah JP, Ghossein R, Singh B.
•  
• Surgery. 2005 Dec;138(6):994-1001; discussion 1001-2.

• Chromosomal aberrations in squamous cell carcinomas of the upper aerodigestive tract: biologic insights and clinical opportunities.

Wreesmann VB, Singh B. 

J Oral Pathol Med. 2005 Sep;34(8):449-59. Review.

• Molecular profiling of tumor progression in head and neck cancer.
•  
• Belbin TJ, Singh B, Smith RV, Socci ND, Wreesmann VB, Sanchez-Carbayo M, Masterson J, Patel S, Cordon-Cardo C, Prystowsky MB, Childs G.
•  
• Arch Otolaryngol Head Neck Surg. 2005 Jan;131(1):10-8.

• Identification of novel prognosticators of outcome in squamous cell carcinoma of the head and neck.

Wreesmann VB, Shi W, Thaler HT, Poluri A, Kraus DH, Pfister D, Shaha AR, Shah JP, Rao PH, Singh B. 

J Clin Oncol. 2004 Oct 1;22(19):3965-72.

• Follicular variant of papillary thyroid carcinoma: genome-wide appraisal of a controversial entity.

Wreesmann VB, Ghossein RA, Hezel M, Banerjee D, Shaha AR, Tuttle RM, Shah JP, Rao PH, Singh B. 

Genes Chromosomes Cancer. 2004 Aug;40(4):355-64.

• Genome-wide profiling of papillary thyroid cancer identifies MUC1 as an independent prognostic marker.

Wreesmann VB, Sieczka EM, Socci ND, Hezel M, Belbin TJ, Childs G, Patel SG, Patel KN, Tallini G, Prystowsky M, Shaha AR, Kraus D, Shah JP, Rao PH, Ghossein R, Singh B. 

Cancer Res. 2004 Jun 1;64(11):3780-9.

• Genetic abnormalities associated with nodal metastasis in head and neck cancer.

Wreesmann VB, Wang D, Goberdhan A, Prasad M, Ngai I, Schnaser EA, Sacks PG, Singh B. 

Head Neck. 2004 Jan;26(1):10-5.

• Human papillomavirus DNA and p53 polymorphisms in squamous cell carcinomas from Fanconi anemia patients.
•  
• Kutler DI, Wreesmann VB, Goberdhan A, Ben-Porat L, Satagopan J, Ngai I, Huvos AG, Giampietro P, Levran O, Pujara K, Diotti R, Carlson D, Huryn LA, Auerbach AD, Singh B.
•  
• J Natl Cancer Inst. 2003 Nov 19;95(22):1718-21.

• Chromosomal aberrations in patients with head and neck squamous cell carcinoma do not vary based on severity of tobacco/alcohol exposure.

Singh B, Wreesmann VB, Pfister D, Poluri A, Shaha AR, Kraus D, Shah JP, Rao PH. 

BMC Genet. 2002 Nov 14;3:22. Epub 2002 Nov 14.

• Genome-wide appraisal of thyroid cancer progression.
•  
• Wreesmann VB, Ghossein RA, Patel SG, Harris CP, Schnaser EA, Shaha AR, Tuttle RM, Shah JP, Rao PH, Singh B.
•  
• Am J Pathol. 2002 Nov;161(5):1549-56.

• Refractory chronic sinusitis: evaluation of symptom improvement after Denker’s procedure.
•  
• Wreesmann VB, Fokkens WJ, Knegt PP.
•  
• Otolaryngol Head Neck Surg. 2001 Nov;125(5):495-500.

• Inflammatory pseudotumour (inflammatory myofibroblastic tumour) of the pancreas: a report of six cases associated with obliterative phlebitis.
•  
• Wreesmann V, van Eijck CH, Naus DC, van Velthuysen ML, Jeekel J, Mooi WJ.
•  
• Histopathology. 2001 Feb;38(2):105-10.

• Screening for genetic aberrations in papillary thyroid cancer by using comparative genomic hybridization.
•  
• Singh B, Lim D, Cigudosa JC, Ghossein R, Shaha AR, Poluri A, Wreesmann VB, Tuttle M, Shah JP, Rao PH.
•  
• Surgery. 2000 Dec;128(6):888-93;discussion 893-4.

Abstracts (Presentations at scientific meetings):

• Genome-wide screening for genetic prognostic factors in papillary thyroid carcinoma.
•  
• Wreesmann VB, Ghossein RA, Poluri A, Shaha AR, Tuttle RM, Shah JP Rao PH, Singh B.

Fifth International Conference on Head and Neck Cancer San Francisco, CA, July 2000.

• Hierarchical Clustering (HC): a Novel Approach to Evaluating the Prognostic Value of Laboratory Parameters in Patients (Pts) Undergoing Chemoradiation Treatment (CRT) for Advanced Laryngopharyngeal Carcinoma (LPC). 

Singh B, Pfister D, Wreesmann VB, Li R, Gogineni S, Bosl G, Hoffman RH, Shah JP, Rao PH. 

37th Annual Meeting of the American Society of Clinical Oncology; New Orleans LA, May 2001.

• Gain of 1q is unique to the tall cell variant of papillary thyroid cancer.

Wreesmann VB, Ghossein RA, Tuttle RM, Shaha AR, Robbins R, Shah JP, Rao PH, Singh B. 

73rd annual meeting of the American Thyroid Association, Washington D.C. November 2001.

• MUC1 is a target of 1q amplification and pertains a grave clinical prognosis in papillary thyroid cancer. 

Wreesmann VB, Sieczka E, Socci ND, Hezel M, Belbin TJ, Childs G, Patel SG, Shah JP, Rao PH, Ghossein RG, Singh B. 

Annual Meeting of the New York Head and Neck Society, New York, NY, March 2002.

• Genome wide screening identified gains and losses as independent prognostic variables in patients with head and neck squamous cell carcinoma (HNSCC). 

Singh B, Wreesmann VB, Thaler HT, Shi W, Shah JP, Shaha AR, Kraus DH, Boyle JO, Pfister D, Rao PH. 

38th Annual Meeting of the American Society of Clinical Oncology; Orlando, Fl May 2002.

• p53 inactivation by human papillomavirus (HPV) in Fanconi anemia associated squamous cell carcinoma. 

Kutler DI, Goberdhan A, Wreesmann VB, Giampietro PF, Auerbach AD, Singh B. 

The Sixth Research Workshop on the Biology, Prevention, and Treatment of Head and Neck Cancer; Washington D.C.; October 2002.

• Identification of novel prognostic factors in head and neck squamous cell carcinoma. 
•  
• Wreesmann VB, Shi W, Thaler HT, Shah JP, Shaha AR, Kraus DH, Boyle JO, Pfister D, Rao PH, Singh B. 

7th symposion on Research in Head and Neck Cancer; Dusseldorf, Germany, September 4-6 2003.

• Molecular profiling of aggressive papillary thyroid cancer: prognostic significance of MUC1 alterations. 

Wreesmann VB, Sieczka E, Socci ND, Hezel M, Belbin TJ, Childs G, Patel SG, Patel KN, Tallini G, Prystowsky M, Shaha AR, Kraus D, Shah JP, Rao PH, Ghossein RA, Singh B. 

7th symposion on Research in Head and Neck Cancer; Dusseldorf, Germany, September 4-6 2003.

• Chromosomal aberrations in Fanconi anemia-associated squamous cell carcinomas differ from sporadic squamous cell carcinomas from the general population. 

Kutler DI, Rao PH, Wreesmann VB, Goberdhan A, Ngai I, Huvos AG, Giampietro PF, Levran O, Pujara K, Diotti R, Auerbach AD, Singh B. 

15th annual Fanconi Anemia Research Fund scientific symposium, Houston TX, Oct 2003.

• Molecular classification of Fanconi anemia(FA)-associated head and neck squamous cell carcinoma (HNSCC) using oligonucleotide microarrays. 

Kutler DI, Ganly I, Wreesmann VB, Goberdhan A, Ngai I, Huvos AG, Giampietro PF, Levran O, Pujara K, Diotti R, Auerbach AD, Singh B. 

15th annual Fanconi Anemia Research Fund scientific symposium, Houston TX, Oct 2003.

•  
• Genotyping follicular cell-derived thyroid neoplasia: a CGH study of 150 cases.

Wreesmann VB, Ghossein RA, Socci N, Shaha AR, Tuttle RM, Shah JP, Rao PH, Singh B. 

Sixth International Conference on Head and Neck Cancer, Washington DC, August 2004.

• Downregulation of Fanconi anemia genes in sporadic squamous cell carcinomas of the head and neck. 

Wreesmann VB, Estilo C, Eisele DW, Singh B, Wang SJ. 

208th meeting of the Netherlands Society of Otolaryngology-Head and Neck Surgery, Utrecht, April 7th 2006.

• Extracapsular nodal spread does not predict outcome in clinically node negative oral cavity squamous cell carcinoma. 

Wreesmann VB, Ghossein RA, Carlson D, Ganly I, Palmer F, Montero P, Shah JP, Patel SG. 

AHNS 2013 Annual Meeting, April 10 & 11, 2013, Orlando Florida.

• Minor (<2mm) extracapsular spread is not an adverse predictor of outcome in metastatic squamous cell carcinoma of the oral cavity. 

Wreesmann VB, Ghossein RA, Carlson D, Ganly I, Palmer F, Montero P, Shah JP, Patel SG. Presented at the AHNS 2014 Annual Meeting, July 2014, New York, New York.

Books, Chapters:

• Molecular Biology as applied to Head and Neck Oncology

Wreesmann VB, Singh B.

Stell and Maran's Textbook of Head and Neck Surgery and Oncology

Fifth Edition

Chapter, edited by John Watkinson and Ralph Gilbert

• Molecular-Cytogenetic Characterization of Head and Neck Cancer: Identification of molecular prognostic factors and targets of therapy

Wreesmann VB, Singh B.

Book, Amsterdam 2004

Reviewed in: Head and Neck: Volume 29, Issue 1, pages 82–83, January 2007

• Open Conservation Surgery for Laryngeal Cancer

Wreesmann VB, Ganly I

Scott-Brown's Otorhinolaryngology and Head and Neck Surgery, Eighth Edition

Chapter 27

CRC Press, Taylor-Francis Group, June 12th, 2018

• Molecular Oncology

Wreesmann V.B.

Self-Assessment in Head and Neck Surgery and Oncology, First Edition

Chapter 21

Elsevier 2014

Research grants:

Netherlands Cancer Institute “Startgeld” Grant 2008

Project: Fanconi anemia in head and neck cancer

Principal investigators: Wreesmann VB, van den Brekel MW, Balm AJM, Vens C.

Amount granted: 300.000 euro

SPECIALTY IN MEDICINE

• Microsurgery
• Cleft lip
• Burn emergency
• Maxillofacial surgery
• Aesthetic surgery
• Tumor surgery
• Nerve injuries
• Reconstructive surgery

EDUCATIONAL BACKGORUND

INONU UNIVERSITY SUBSPECIALTY IN MEDICINE

2010-2014

FACULTY OF MEDICINE

INONU UNIVERSITY SPECIALTY IN MEDICINE

2002-2007

FACULTY OF MEDICINE/DIVISION OF SURGICAL MEDICINE SCIENCES/DEPARTMENT OF PLASTIC AND RECONSTRUCTIVE SURGERY

INONU UNIVERSITY SPECIALTY IN MEDICINE

2002-2007

FACULTY OF MEDICINE/DIVISION OF SURGICAL MEDICINE SCIENCES/DEPARTMENT OF PLASTIC AND RECONSTRUCTIVE SURGERY

Thesis name: Analysis of the long-term results of four different techniques with a new method in patients who underwent a reduction mammoplasty (2007) Thesis Supervisor: (ALI GÜRLEK)

POSITIONS

• PROFESSOR

2019 İNÖNÜ ÜNİVERSITY/FACULTY OF MEDICINE

• ASSOCIATE PROFESSOR

2013 İNÖNÜ ÜNİVERSITY/FACULTY OF MEDICINE

• EDUCATION COORDINATOR

2011 İNÖNÜ ÜNİVERSITY/FACULTY OF MEDICINE

• ASSISTANT PROFESSOR

2008

INONU UNIVERSITY/FACULTY OF MEDICINE, DIVISION OF SURGICAL MEDICINE SCIENCES, DEPARTMENT OF PLASTIC AND RECONSTRUCTIVE SURGERY

MANAGED THESES

2014

ΑΥΤΕΚΙΝ ΑΗΜET HAMDI, (2014). Comparison of the effects of PRP and hyaluronic acid injections into allogeneic vascular graft on nerve regeneration in the treatment of peripheral nerve defects, Inonü University->Faculty of Medicine->Department of Plastic Reconstructive and Aesthetic Surgery

2012

GEYİK YILMAZ, (2012). Comparison of reconstruction methods, where vessel, and cartilage grafts are used, in peripheral nerve injuries and analysis of a new technique, İnönü University->Faculty of Medicine->Department of Plastic Reconstructive and Aesthetic Surgery     

PROJECT TASKS

*Effects of Chrysin on burn wound healing, 1st scientific research project, which is supported by Higher Education Institutions, Researcher: FIRAT CEMAL, Researcher: OĞUZTÜRK HAKAN, Coordinator: TURTAY MUHAMMETGÖKHAN, Researcher: ÇİFTÇİ OSMAN, 01:092013-Glucan treatment prevents progressive burn ischaemia in the zone of stasis and improves burn healing. An experimental study in rats Firat C Samdanci E Erbatur S Aytekin AH AK M Turtay MG

Coban YK Burns 2012 Mar 31 Inönü University Scientific Research Project Responsible coordinator, BAP, Supervisor, 2010-2014 (ΝΑΤΙΟNAL) Cerium nitrate treatment prevents progressive tissue necrosis in the zone of stasis following burn

Eski M Ozer F Firat C Alhan D Arsian N Senturk T İşik S Burns 2012 Mar 38 2 2839 Epub 2011 Oct 19 Ankara Gulhane Military Medical Academy Scientific Research Project Researcher, BAP, Researcher, 2010-2011 (NATIONAL)

Dr. Denizhan Özkaya is a distinguished Ear, Nose, and Throat (ENT) specialist based in İzmir, Turkey, with a medical career spanning over 38 years. Born in 1964 in İzmir, he graduated from Ege University Faculty of Medicine in 1987. In 2000, he completed his specialization in ENT at Celal Bayar University Faculty of Medicine.

In 2001, Dr. Özkaya co-founded the Private ENTO Ear Nose and Throat Clinic in Alsancak, İzmir, with Dr. Ümit Filiz. The clinic has since evolved into the ENTO Surgical Medical Center, where Dr. Özkaya continues to perform surgeries for both domestic and international patients.

Dr. Doğukan Aydenizöz Clinic in Antalya is a trusted destination for
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