Best MRI of one area doctors: TOP 461 doctors

Professor Dihné is a true master in understanding the subtle mechanisms of the nervous system. His professionalism is manifested in his profound knowledge of anatomy and physiology, as well as in his ability to accurately identify and effectively treat diseases that can affect both the physical and psychological state of the patient. Professor Dihné listens carefully to everyone, creating an atmosphere of trust, and based on thorough examinations and analyses, develops an individualized treatment plan. He not only has knowledge in his hands, but also the ability to feel and understand how to restore harmony in a person's body and mind, giving them back their quality of life.

Membership in societies and awards:

German Society of Physicians. 

Research Award of the Christian and Claudia Hempel Foundation for outstanding research in the field of clinical stem cell research.

Author of numerous publications in leading medical journals in Germany and Europe.

Specialization:

• neurology
• strokes
• epilepsy
• nervous system regeneration
• stem cells
• microelectrode arrays

Work experience:

2001-2004: Training at the Centre for Molecular Neurobiology in Hamburg.

2004-2011: Training at the Neurological University Clinic Düsseldorf.

2011-2013: Training at the Neurological University Hospital Tübingen and the Hertie Institute for Clinical Brain Research. 

Professor Dihne began his scientific career at the University of Düsseldorf. 

2013-2023  Professor Dihne successfully headed the Department of Neurology at the St. Lukas Klinik Solingen for 10 years.

Since 2024: Chief Physician at the Department of Neurology at the Academic Hospital Solingen.

Dr. Séverine Iborra is the Chief Physician of the Department of Gynecology and Obstetrics at Städtisches Klinikum Solingen. Her responsibilities include obstetrics, the delivery room, the neonatal unit, and gynecology. The department also includes the Senology/Breast Clinic at the Bergisches Breast Center Solingen, led by Dr. Manuela Seifert.

Dr. Séverine Iborra is originally from France. She began her medical studies at the University of Lyon and later transferred to Albert-Ludwigs University in Freiburg, where she received her medical license in 2007. She earned her doctorate in 2008 for experimental research in molecular oncology. From August 2008 to November 2013, Dr. Iborra worked as a resident at the University Women’s Clinic in Freiburg. After passing her specialist exams in gynecology and obstetrics, she continued her career as a specialist at the same clinic. In November 2015, she moved to RWTH University Hospital Aachen as a senior physician.

At the Clinic for Gynecology and Obstetrics, under the leadership of Prof. Dr. E. Stickeler, Dr. Iborra led the obstetrics department from 2017 to 2019. Since December 2017, she was responsible for organizing education in the department, and in October 2019, she became the Managing Senior Physician and Personnel Senior Physician of the clinic, a position she held until she moved to Solingen.

In addition to her scientific work, with numerous publications and presentations at major gynecological conferences, Dr. Iborra deepened her medical specialties. She obtained certifications in oncological diagnostics and therapy from the Gynecological Oncology Working Group, as well as additional qualifications in Cervical Pathology and Colposcopy (AGCPC), Urogynecology and Pelvic Reconstructive Surgery (AGUP), and the Professional Association of Gynecologists (BVF).

In 2019, Dr. Iborra successfully completed further specialization in “Gynecological Oncology” and “Special Obstetrics and Perinatal Medicine.” She is an active member of leading German medical societies in her field, including the German Society for Gynecology and Obstetrics, the Cervical Pathology and Colposcopy Working Group, and the German Society for Prenatal and Birth Medicine.

Treatments Offered in Our Gynecology Department

• Hysteroscopy and Dilation and Curettage (D&C) for diagnostic and therapeutic purposes.
• Removal of abnormal or symptomatic ovarian findings, such as cysts, while preserving the remaining ovary.
• Oophorectomy (removal of ovaries) in cases of abnormalities or preventively when indicated.
• Myomectomy (removal of uterine fibroids) while preserving the uterus.
• Conservative treatment of fibroids: either medication or embolization performed by radiology specialists.
• Hysterectomy with or without removal of the cervix.
• Diagnosis and clarification of unclear findings in the cervix, vagina, and vulva.
• Dysplasia treatment.
• Endometriosis management.
• Cancer treatment for vulvar, vaginal, cervical, uterine, and ovarian cancers.
• Treatment for incontinence and/or pelvic organ prolapse.

Whenever possible, we offer all procedures as minimally invasive treatments using laparoscopy or the Da Vinci robotic system.

Dr. Victor Alexander Krol - Chief of Gastroenterology, Internal Medicine and Obesity Treatment Center at Martinus Hospital

Dr. Victor Alexander Krol is a highly qualified specialist, heading the departments of gastroenterology and internal medicine. With many years of experience and deep knowledge in his field, Dr. Krol has established himself as an outstanding expert, providing patients with comprehensive treatment and an individual approach. He actively uses the latest methods of diagnosis and treatment of diseases of the gastrointestinal tract, metabolism, as well as diseases of the cardiovascular and respiratory systems.

Dr. Krol is also the director of the certified Obesity Treatment Center at Martinus Hospital, which provides surgical and endoscopic treatments for obesity. The center uses advanced technology to diagnose and treat obesity (adiposis), including methods such as bariatric surgery, endoscopic weight loss, and specialized programs for patients with different stages of obesity. The center is certified to high standards and has excellent results in the treatment of this serious disease.

The Gastroenterology Department, headed by Dr. Krol, diagnoses and treats diseases of the stomach, intestines, liver, pancreas, and gallbladder. The doctors of the department use a wide range of methods, including endoscopic procedures, ultrasound, and other modern diagnostic technologies.

The Department of Internal Medicine covers a wide range of diseases, including cardiology, diabetology, infectology, and therapy of respiratory and renal diseases. Dr. Krol and his team provide a comprehensive approach to treatment using the most advanced methods of medicine.

Thanks to his high professionalism and humane approach to each patient, Dr. Krol deservedly enjoys the respect of colleagues and patients.

Prof. Emin Tireli, MD, is a leading pediatric cardiovascular surgeon. He has performed over 6,329 congenital cardiac surgeries since 1993. He is known worldwide for being one of the first to use the complex Nikaidoh procedure for transposition of the great arteries (TGA).

Dr. Tireli performs more than 100 neonatal cardiac surgeries each year. His expertise includes arterial switch operations, total pulmonary return anomalies, pulmonary banding, and Norwood procedures. He has used hybrid techniques in 15 cases. Dr. Tireli has also completed 30 reconstructions of aortic anomalies and many PDA ligations in extremely low birth weight infants. His work greatly supports neonatal care.

Prof. Luigi Massimo Zagra is the Head of the Hip Surgery Department I at the IRCCS Istituto Ortopedico Galeazzi in Milan.

He is the visiting professor at the School of Specialization in Orthopaedics and Traumatology of the University of Milan.

Prof. Zagra has performed more than 5,000 major orthopaedic operations.

Mainly focused on hip surgery including complex primary, revision (25% of cases), conservative surgery, osteotomies, and pediatric hip diseases arthroplasty.

He performs hip replacement surgery daily for osteoarthritis, particularly in cases of congenital dysplasia, developmental and post-traumatic malformations, rheumatoid arthritis, necrosis in young and old patients, needing special implants to prevent any possible complications. 

Dealing with problems with previously placed implants, in particular material wear and tear, such as in metal-on-metal or old-generation polyethylene prostheses, painful, loose, unstable, infected prostheses, using tissue-safe and non-invasive methods and the latest ceramic and titanium implants, including cemented ones.

He is currently Chairman of the Scientific Committee of the European Hip Society and the Italian Hip Society, as well as a member of the Executive Committee of EFORT, of International Committee of the American Association of Hip and Knee Surgeons and of the Scientific Committee of the Italian Arthroplasty Registry. 

He is author and co-author of 130 articles published in national and international journals, as well as invited specialist and speaker at over 500 congresses in Italy and abroad.

Professional experience

Since 2006, he has been Head of the Neurology Department at the Quironsalud University Hospital of Madrid and the Ruber Juan Bravo Hospital.

Professor of Medicine at the Faculty of Biomedical Sciences of the European University of Madrid, holds the national accreditation of Professor of Medical Sciences (issued by ANECA).

Doctor of Medicine, Complutense University of Madrid (UCM). Award for Outstanding Doctoral Thesis (UCM, 2004): Study on the relationship of human herpes virus 6 as an environmental factor in multiple sclerosis.

Membership in scientific societies

National and International Principal Investigator in Neuroscience at Quironsalud Madrid (June 2015 – present)

President of the Research Committee of the Quironsalud University Hospital of Madrid (2012 to present).

Member of the Research Committee of the San Carlos Clinical Hospital (2012-2015).

Member of the Council of the Faculty of Medicine of the Complutense University of Madrid (2011-2015).

Research and Teaching

Principal investigator of 100 national and international clinical trials.

7 FIS research projects from the Carlos III Institute of Health (the last 5 as principal investigator).

10 projects from private foundations, received on a competitive basis (7 as principal investigator).

He has authored 139 international articles with a total impact factor of 949,917 and 4,552 citations. 38 books and book chapters with an H-factor of 34 (2018).

His publications stand out in journals that have the greatest global impact on research, such as the New England Journal of Medicine and the Lancet.

Dr. Rafael Arroyo has given over 300 international and national presentations at various Congresses.

Education :

Professor of Medicine at the Faculty of Biomedical Sciences of the European University of Madrid and holds the national accreditation of Professor of Medical Sciences (issued by ANECA).

PROFESSIONAL EXPERIENCE

2011-2012
Erzurum Koprukoyu State Hospital
Department: General Medicine

2012-2017
Istanbul University Cerrahpaşa Medical Faculty
Department: Internal Medicine

06/2017-10/2017
Istanbul Gaziosmanpasa Taksim Training and Research Hospital
Department: Internal Medicine

10/2017-11/2018
Istanbul University Istanbul Medical Faculty
Department: Allergy and Immunology Fellowship

2018/2022
Istanbul University Oncology Institute
Department: Medical Oncology Fellowship

2022-2023
Tekirdag City Hospital
Department: Medical Oncology Specialist

2023-present
Istanbul Medipol University Medipol Bahcelievler Private Hospital
Department: Medical Oncology Assoc. Prof.

EDUCATION

2005-2011
Medical Education
Sivas Cumhuriyet University Medical Faculty, Sivas, Turkey

2012-2017
Internal Medicine
Istanbul University Cerrahpaşa Medical Faculty, Department of Internal Medicine, Istanbul, Turkey

2017-2018
Allergy-Immunology Fellowship
Istanbul University Istanbul Medical Faculty
Department of Internal Medicine, Division of Allergy and Immunology, Istanbul, Turkey

2018-2022
Medical Oncology Fellowship
Istanbul University Oncology Institute, Department of Medical Oncology, Istanbul, Turkey

2022
ESMO Board Certification in Medical Oncology
10th September 2022 in Paris, France.

2023
Medical Oncology Assoc. Prof.
Istanbul Medipol University Department of Medical Oncology, Istanbul, Turkey

INTERNATIONAL CLINICAL TRIALS:

1. Astefania - ROCHE

• Title: A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy
• Role: Subinvestigator

2. PFİZER

• Title: A Study Of Lorlatinib Versus Crizotinib In First-Line Treatment Of Patients With ALK-Positive NSCLC
• Role: Subinvestigator

3. RECITE - AMGEN

• Title: Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Gastrointestinal, Pancreatic, or Colorectal Cancer
• Role: Subinvestigator

4. NAVIGATE - BAYER

• Title: A Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid Tumors
• Role: Subinvestigator

5. RUBY - Tesaro (PRA)

• Title: A Phase 3, Randomized, Double-blind, Multicenter Study of Dostarlimab (TSR-042) Plus Carboplatin-paclitaxel Versus Placebo Plus Carboplatin-paclitaxel in Patients With Recurrent or Primary Advanced Endometrial Cancer
• Role: Subinvestigator

6. ENGOT-ov43/GOG-3036 - MSD

• Title: Study of Chemotherapy With Pembrolizumab (MK-3475) Followed by Maintenance With Olaparib (MK-7339) for the First-Line Treatment of Women With BRCA Non-mutated Advanced Epithelial Ovarian Cancer (EOC) (MK-7339-001/KEYLYNK001/ENGOT-ov43/GOG-3036)
• Role: Subinvestigator

7. ASTRA ZENECA

• Title: To Study Clinical Effectiveness and Safety of Olaparib Monotherapy in Metastatic Breast Cancer Patients.
• Role: Subinvestigator

8. ROSY-O - ASTRA ZENECA

• Title: Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib
• Role: Subinvestigator
•  

INTERNATIONAL PUBLICATIONS

I. Published journal articles indexed by SCI, SSCI, and AHCI

Weekly Paclitaxel in Classic Kaposi Sarcoma

• Authors: Paksoy, N., Khanmammadov, N., Doğan, İ., Ferhatoğlu, F., Ahmed, M. A., Karaman, S., & Aydiner, A.
• Journal: Medicine, 102(5)

Carboplatin Desensitization in Ovarian Carcinoma

• Authors: Paksoy, N., Khanmammadov, N., Doğan, İ., Ferhatoğlu, F., Yildiz, A., Ak, N., & Aydiner, A.
• Journal: Medicine, 101(45), e31726

High-Dose Chemotherapy for Ewing’s Sarcoma

• Authors: Paksoy, N., Ferhatoglu, F., Dogan, İ., Khanmammadov, N., Celik, A. I., Gulbas, Z., & Başaran, M.
• Journal: Medicine, 101(49), e32213

Multidrug Refractory TFE3(+) Renal Cell Carcinoma

• Authors: Paksoy, Nail, et al.
• Journal: Journal of Oncology Pharmacy Practice, 2022, 28.1: 215-221

Crizotinib Efficacy in NSCLC with MET Alterations

• Authors: Gürbüz, M., Kiliçkap, S., Bilici, A., Karadurmuş, N., Sezer, A., Şendur, M. A. N., ... & Demirkazik, A.
• Journal: Medicine, 101(50), e32368

Clinicopathological Features in ALK Mutant NSCLC

• Authors: Dogan, I., Gurbuz, M., Paksoy, N., Ferhatoglu, F., Vatansever, S., Saip, P., ... & Aydiner, A.
• Journal: Medicine, 101(34)

PSMA-Based Tumor Burden in Prostate Cancer

• Authors: HAS SIMSEK, Duygu, et al.
• Journal: Annals of Nuclear Medicine, 2021, 35.6: 680-690

Atezolizumab in Metastatic Urothelial Carcinoma

• Authors: TURAL, Deniz, et al.
• Journal: European Urology Focus, 2021, 7.5: 1061-1066

Pulmonary Sarcomatoid Carcinoma

• Authors: FERHATOGLU, Ferhat, et al.
• Journal: Oncology Research and Treatment, 2021, 44.11: 590-601

Prognostic Factors in Atezolizumab-Treated Urothelial Carcinoma

• Authors: TURAL, Deniz, et al.
• Journal: International Journal of Clinical Oncology, 2021, 26.8: 1506-1513

Atezolizumab with Chemotherapy in Small Cell Lung Cancer

• Authors: GÜRBÜZ, Mustafa, et al.
• Journal: Journal of Cancer Research and Clinical Oncology, 2022, 1-9

FOLFIRINOX vs. Gemcitabine + Nab-Paclitaxel in Pancreatic Cancer

• Authors: AY, Seval, et al.
• Journal: Journal of Chemotherapy, 2022, 1-7

Trastuzumab Emtansine in Older HER2-Positive Breast Cancer Patients

• Authors: CIL, Ibrahim, et al.
• Journal: Tumori Journal, 2022, 108.1: 19-25

Real-Life Efficacy of Osimertinib in Advanced NSCLC

• Authors: HIZAL, Mutlu, et al.
• Journal: Journal of Cancer Research and Clinical Oncology, 2022, 148.6: 1501-1508

ALK-Positive Cells Percentage and Alectinib Efficacy

• Authors: Hizal, M., Bilgin, B., Paksoy, N., Atcı, M. M., Kahraman, S., Kılıçkap, S., ... & Şendur, M. A. N.
• Journal: Journal of Cancer Research and Clinical Oncology, 149(8), 4141-4148

Real-World Data on Alectinib in ALK-Positive NSCLC

• Authors: Hizal, M., Bilgin, B., Paksoy, N., Kılıçkap, S., Atcı, M. M., Kahraman, S., ... & Şendur, M. A. N.
• Journal: Future Oncology, 18(23), 2573-2582

Prognostic Factors in Metastatic RCC with T790M Mutation

• Authors: Dogan, I., Iribas, A., Paksoy, N., Vatansever, S., & Basaran, M.
• Journal: Journal of Cancer Research and Therapeutics

FLOT Regimen in Metastatic Gastric Cancer

• Authors: Tastekin, D., Paksoy, N., Dogan, I., Ferhatoglu, F., Khanmammadov, N., Bozbey, H. U., & Karabulut, S.
• Journal: Journal of Cancer Research and Therapeutics

Desensitization Protocol in Lenalidomide Hypersensitivity Reactions

• Authors: DEMIR, Semra, et al.
• Journal: Annals of Allergy, Asthma & Immunology, 2019, 123.4: 394-397

Factors Associated with Diagnostic Skin Test Positivity in PPI Hypersensitivity

• Authors: ÖZDEMIR, Seçil Kepil, et al.
• Journal: Allergy, 2019, 74.6: 1187-1190

Efficacy of Capecitabine and Temozolomide in Neuroendocrine Tumors

• Authors: Ünal, Ç., Azizy, A., Karabulut, S., Taştekin, D., Akyıldız, A., Yaşar, S., ... & Sağlam, S.
• Journal: The Oncologist, oyad257

Subsequent Treatments in Hormone-Positive Breast Cancer Progression

• Authors: Karacin, C., Oksuzoglu, B., Demirci, A., Keskinkılıç, M., Baytemür, N. K., Yılmaz, F., ... & Hacıbekiroğlu, İ.
• Journal: BMC cancer, 23(1), 192

Termination of Trastuzumab in HER2-Positive Metastatic Breast Cancer

• Authors: Dogan, I., Aydin, E., Khanmammadov, N., Paksoy, N., Saip, P., & Aydiner, A.
• Journal: Scientific Reports, 13(1), 8779

Long-term Outcomes and Predictors of Recurrence in Node-Negative Early Stage Breast Cancer

• Authors: Dogan, I., Aydin, E., Khanmammadov, N., Paksoy, N., Ferhatoğlu, F., Ak, N., ... & Aydiner, A.
• Journal: Journal of Cancer Research and Clinical Oncology, 1-9

Prognostic Factors Influencing PFS in HER2-Positive Metastatic Breast Cancer

• Authors: Doğan, İ., Paksoy, N., Ak, N., Vatansever, S., Saip, P., & Aydıner, A.
• Journal: European Journal of Breast Health, 19(2), 128

Treatment Efficacy of Ribociclib or Palbociclib plus Letrozole in Metastatic Breast Cancer

• Authors: Kahraman, S., Erul, E., Seyyar, M., Gumusay, O., Bayram, E., Demirel, B. C., ... & Nahit Sendur, M. A.
• Journal: Future Oncology, 19(10), 727-736

Efficacy and Safety of Sorafenib in Adult Metastatic Osteosarcoma Patients

• Authors: Dogan, I., Paksoy, N., & Basaran, M.
• Journal: Journal of Cancer Research and Therapeutics

Single-Agent Temozolomide as Salvage Therapy in Heavily Pretreated Metastatic Sarcoma Patients

• Authors: Dogan, I., Paksoy, N., & Basaran, M.
• Journal: Journal of Cancer Research and Therapeutics

Outcomes and Prognostic Factors in Metastatic Renal Cell Carcinoma with Brain Metastases

• Authors: Dogan, I., Iribas, A., Paksoy, N., Vatansever, S., & Basaran, M.
• Journal: Journal of Cancer Research and Therapeutics

FLOT Regimen in First-Line Treatment of Metastatic Gastric Cancer

• Authors: Tastekin, D., Paksoy, N., Dogan, I., Ferhatoglu, F., Khanmammadov, N., Bozbey, H. U., & Karabulut, S.
• Journal: Journal of Cancer Research and Therapeutics

Prognostic Factors of Perioperative FLOT Regimen in Operable Gastric Cancer

• Authors: Erol, C., Sakin, A., Basoglu, T., Ozden, E., Cabuk, D., Dogan, M., ... & Sendur, M. A. N.
• Journal: [Not specified]

Efficacy and Outcomes of Systemic Chemotherapy in Posttransplant Kaposi Sarcoma

• Authors: Khanmammadov, N., Paksoy, N., Doğan, I., Ferhatoğlu, F., Saip, P., & Aydiner, A.
• Journal: Medicine, 102(39), e35383

Comparison of Second-Line Treatments in Metastatic Renal Cell Carcinoma

• Authors: Pehlivan, M., Paksoy, N., Aydin, E., Basaran, M., & Ekenel, M.
• Journal: Medicine, 102(41), e35245

Toxicity Management and Effectiveness of Regorafenib in Advance GIST Patients: A Real-world Study - Authors: Paksoy, N., Ferhatoğlu, F., Doğan, İ., Khanmammadov, N., Bozbey, H. U., Karabulut, S., & Taştekin, D. - Journal: TURKISH JOURNAL OF ONCOLOGY, 1(1)

Demographic and Clinical Features and Factors Associated with Survival in Patients with Primary Glomerulonephritis: Single Tertiary Center Experience - Authors: Paksoy, N., Trabulus, S., Seyahi, N., & Altiparmak, M. R. - Journal: Namik Kemal Tip Dergisi, 11(1)

Efficacy of Sorafenib in Symptomatic Patients with Pretreated Progressive Desmoid Tumors - Authors: Paksoy, N., Ferhatoglu, F., Dogan, I., Ak, N., Pehlivan, M., Ekenel, M., & Basaran, M.

Nodal Response to Neoadjuvant Chemotherapy is a Better Predictive Factor of Survival Than Miller-Payne Scoring in Breast Cancer - Authors: Ak, Naziye, et al. - Journal: Journal of Oncological Sciences, 7.2: 42-49

Evaluation of Prognostic and Predictive Values of Hemogram Parameters in Patients with Advanced Stage Ovarian Carcinoma - Authors: Ak, Naziye, et al. - Journal: Turkish Journal of Oncology/Türk Onkoloji Dergisi, 2021, 36.4

Identifying Risk Factors Associated with Survival and Drug-Related Toxicities in Imatinib-Resistant Gastrointestinal Stromal Tumor (GIST) Patients Treated with Sunitinib - Authors: Ferhatoglu, F., Karabulut, S., Paksoy, N., & Tastekin, D.

Real-life Outcomes of ROS1 Fusion-positive Metastatic Lung Cancer Patients who were Treated with Crizotinib - Authors: Dogan, İ., Khanmammadov, N., Paksoy, N., Ferhatoglu, F., Aydın, E., Vatansever, S., & Aydine, A. - Journal: TURK ONKOLOJI DERGISI-TURKISH JOURNAL OF ONCOLOGY

Predictors of the acquisition of T790M mutation in EGFR-mutant metastatic lung cancer patients who were treated with EGFR inhibitors - Authors: Dogan, I., Khanmammadov, N., Paksoy, N., Vatansever, S., Saip, P., & Aydıner, A. - Journal: Eurasian Journal of Pulmonology

Laterality of Adrenal Gland Metastasis in Lung Cancer: Results of a Comparative Study - Authors: Ferhatoglu, F., Gagatay, T., Okumus, G., Aydiner, A., Paksoy, N., Ak, N., ... & Saip, P. - Journal: Eurasian Journal of Medical Investigation, 7(2)

Poor Risk Factors Affecting Cancer Patients Infected with Covid-19: A Retrospective Comparative Study from a Pandemic Hospital - Authors: Ferhatoglu, F., Kapağan, T., Paksoy, N., Ak, N., Medetalibeyoğlu, A., Şenkal, N., ... & Vatansever, S. - Journal: Turk Onkoloji Dergisi, 38(1)

Systemic Treatment Outcomes of Progressive Medullary Thyroid Carcinoma from the Registries of a Tertiary Cancer Center - Authors: Ferhatoglu, F., Paksoy, N., & Başaran, M. - Journal: Namik Kemal Tip Dergisi, 10(4)

Evaluation of clinical features and risk factors related to late recurrence (> 5 years) in patients with breast cancer - Authors: Ferhatoglu, F., Aydiner, A., & Paksoy, N. - Journal: Journal of Surgery & Medicine (JOSAM), 6(12)

Assessing the Clinical Impact of Lutetium-177 DOTATATE Peptide Receptor Radionuclide Therapy (PRRT) on Metastatic Neuroendocrine Tumors: A Multicenter Real-World Data from Türkiye

Thesis:

Istanbul University Cerrahpaşa Medical Faculty, Internal Medicine Department PAKSOY, Nail. Demographical, clinical characteristics and survival factors in patients withprimary glomerulonephritis: Cerrahpasa Medical Faculty Experience. (2016)

International Refereed Congress / Symposium Publications in Proceedings (ASCO/ESMO Abstracts)

Prognostic factors influencing progression-free survival in HER2 positive metastatic breast cancer patients who treated with lapatinib and capecitabine combination

• Authors: Dogan, I., Paksoy, N., Ak, N., Vatansever, S., Saip, P., & Aydiner, A. (2022)

Efficacy of regorafenib and 5-fluorouracil-based rechallenge treatment in the third-line treatment of metastatic colorectal cancer: A Turkish oncology group study

• Authors: Şenocak Taşçi, E., Oyan, B., Sonmez, O., Mutlu, A. U., Atcı, M. M., Oner, I., ... & Gulmez, A. (2022)

Long-term outcomes and predictors of recurrence in patients with early-stage node-negative breast cancer

• Authors: Dogan, I., Aydin, E., Paksoy, N., Ferhatoglu, F., Ak, N., Ibis, K., ... & Aydiner, A. (2021)

Efficacy of temozolomide in pretreated patients with metastatic sarcoma

• Authors: Paksoy, N., Dogan, I., Ekenel, M., & Basaran, M. (2021)

Efficacy of sorafenib in symptomatic patients with pretreated progressive desmoid tumors

• Authors: Ferhatoglu, F., Paksoy, N., Dogan, I., Ak, N., Pehlivan, M., Ekenel, M., & Basaran, M. (2021)

Efficacy of sorafenib in heavily pretreated adult patients with metastatic osteosarcoma

• Authors: Paksoy, N., Dogan, I., Ekenel, M., & Basaran, M. (2021)

Outcomes and prognostic factors in metastatic renal cell carcinoma patients with brain metastases

• Authors: Dogan, İ., Iribas, A., Paksoy, N., Ekenel, M., Vatansever, S., & Basaran, M. (2021)

Association of response to first-line chemotherapy with the efficacy of atezolizumab in patients with metastatic urothelial carcinoma

• Authors: Tural, D., Olmez, O. F., Sümbül, A. T., Artac, M., Ozhan, N., Akar, E., ... & Erman, M. (2021)

Safety and survival in adult women with platinum-sensitive relapsed BRCA mutant ovarian cancer: A study of patients in Olaparib Turkey Early Access Program—LynTurk study

• Authors: Esin, E., Ahmed, M. A., Yıldırım, H. Ç., Mandel, N. M., Erdemoglu, E., Sari, M., ... & Paydas, S. (2023)

Atezolizumab in patients with metastatic urothelial carcinoma who have progressed after first-line chemotherapy: Results of real-life experiences

• Authors: Tural, D., Ölmez, Ö. F., Sümbül, A. T., Artaç, M., Özhan, N., Akar, E., ... & Kılıçkap, S. (2021)

Education

• 1986-1989, Bursa High School, Bursa, Turkey
• 1989-1995, Istanbul University, Istanbul School of Medicine, Turkey
• 1999-2003, (Residency) Kadir Has University, School of Medicine, Department of Radiation Oncology, Istanbul, Turkey
• 2015, (Associate Professor) Demiroglu Bilim University, Department of Radiation Oncology, Istanbul, Turkey
• 2021, (Professor) Demiroglu Bilim University, Department of Radiation Oncology, Istanbul, Turkey
• 2024, Istanbul Medipol University, Department of Radiation Oncology, Istanbul, Turkey

Experience

• 1995-1999, Şişli Florence Nightingale Hospital, Istanbul, Cardiology Department
• 2003, Gayrettepe Florence Nightingale Hospital, Istanbul, Department of Radiation Oncology
• 2015, (Associate Professor in Radiation Oncology) Demiroglu Bilim University, Department of Radiation Oncology, Istanbul, Turkey
• 2021, (Professor in Radiation Oncology) Demiroglu Bilim University, Department of Radiation Oncology, Istanbul, Turkey
• 2024, Istanbul Medipol University, Department of Radiation Oncology, Istanbul, Turkey

Education

• (2004 – 2011), Faculty of Medicine/ Inonu University/ Malatya, Turkiye
• (2011 – 2015), Department of Radiology/ Bagcilar Training and Research Hospital/ Istanbul, Turkiye

Career

• (2016 – 2020), Diagnostic and Interventional Radiologist/ Mus State Hospital/ Mus,Turkiye
• (2020 – 2022), Assistant Professor of Diagnostic and Interventional Radiology/ Sakarya University Training and Research Hospital/ Sakarya, Turkiye
• (2023 – 2024), Associate Professor of Diagnostic and Interventional Radiology /Sakarya University Training and Research Hospital/ Sakarya, Turkiye
• (2024 - Present), Associate Professor of Diagnostic and Interventional Radiology /Medipol University Hospital/ Istanbul, Turkiye

Professor Markus Dukes is a specialist in diagnostic radiology and minimally invasive therapy.

Awards

• Gold Medal of Honorary Professor of Osaka Medical University (Japan).
• Honorary member of DeGIR (German Society for Interventional Radiology and Minimally Invasive Therapy).

Education and professional experience

• 1982-1988 - study of human medicine at the Johannes-Gutenberg University in Mainz.
• 1988 - approval and medical license.
• 1988-1989 - Medical officer of the Bundeswehr.
• 1990 - Candidate of Medical Sciences in the field of radiology, subject: “Investigation of the influence of dilation speed on its success, as well as on damage to the vessel walls during balloon expansion”, at the Johannes-Gutenberg University in Mainz.
• 1990-1996 - Resident in the Department of Radiology at the Ruprecht-Karls University.
• 1996 - Senior physician in the Department of Radiodiagnostics at the Ruprecht-Karls University of Heidelberg.
• 1998 - Doctorate in Diagnostic Radiology, topic: "Direct comparison of imaging methods for gastric carcinoma: the importance of optimized examination methods in clinical practice and first experience with magnetic resonance imaging."
• 2000 - Deputy Head of the Department of Radiology, Department of Radiodiagnostics at the Ruprecht-Karls University of Heidelberg.
• 2000-2002 - Head of the Image Processing Center at the Orthopedic Clinic of the University of Heidelberg.
• 2002-2003 - Head of the Department of Radiology, Surgical Clinic, Department of Radiology at the Ruprecht-Karls University of Heidelberg.
• 2003 - Chief Physician of the Central Institute of Radiology and Neuroradiology at the Nordwest Clinic in Frankfurt am Main.
• 2006 - Associate Professor in the Department of Radiology at the University of Heidelberg.

Scientific activity

Marcus Dukes is one of the first physicians to perform minimally invasive microwave ablation of liver and lung tumors under CT guidance.

Clinical activities

The professor heads the first and only MRI-guided FUS ablation center in the Rhine-Main region. In most cases, the procedure allows avoiding surgical intervention. Patients of the center have access to ablation for prostate cancer, bone and liver metastases, benign tumors, and treatment of uterine fibroids without surgery.

Membership in organizations

• DRG (German Society of Radiologists).
• DeGIR (German Society for Interventional Radiology and Minimally Invasive Therapy).
• RSNA (Radiological Society of North America).
• ESGAR (European Society of Gastrointestinal and Abdominal Radiology).
• CIRSE (Cardiovascular and Interventional Radiology Society of Europe).
• ECR (European Congress of Radiology).
• EUFUS (European FUS Society).
• MEDICA (German Society for Interdisciplinary Medicine).

Associate Professor Dr. Yusuf AÇIKGÖZ
Specialization: Medical Oncology

Education:

• 2004-2011: İnönü University Faculty of Medicine
• 2011-2016: Ankara Numune Training and Research Hospital, Internal Medicine
• 2017-2022: Health Sciences University, Medical Oncology

Professional Experience:

• 2016-2017: Bingöl City Hospital, Internal Medicine
• 2021-2022: Health Sciences University, Medical Oncology
• 2022-2023: Kastamonu Education and Research Hospital, Medical Oncology
• 2023-2024: Ohio State University, Medical Oncology
• 2024-Present: Lokman Hekim University, Medical Oncology, Ankara Hospital

Clinical Trials, Courses, Certifications:

Clinical Trials:

• 2017-2021: Phase III, CheckMate-649 Study (Assistant Investigator)
• 2022-Present: Phase III, Fortitude-101 Study (Assistant Investigator)

Courses:

• 2018: Medicres Basic and Advanced Biostatistics Training Program (ongoing), Istanbul-Vienna
• 2019: Immuno-Oncology Education Course, March 1-2, 2019, Vienna, Central European Cooperative Oncology Group (CECOG)
• 2018: Good Clinical Practice Certification, April 7-8, 2018, Ankara, Health Sciences University
• 2017: Basic Oncology Training Program, November 25-26, 2017, Adana, Clinical Oncology Society
• 2016: Basic Ultrasonography Course (10 hours theoretical + 10 hours practical), September 24-25, 2016, Ankara, Turkish Emergency Medicine Association

Certifications:

• Ongoing: ECFMG Certification
• 2024: CITI Responsible Conduct of Research (The Ohio State University)
• 2024: CITI IACUC-Laboratory Animal Research (The Ohio State University)
• 2024: CITI Human Subjects Protection (The Ohio State University)
• 2024: CITI Good Clinical Practice (The Ohio State University)
• 2023: Occupational English Test (OET)
• 2019: International English Language Testing System (IELTS), Total Score: 6.5, May 26, 2019, Ankara, British Council
• 2017: USMLE Step 2 CK Exam; Score: 244, February 7, 2017
• 2016: USMLE Step 1 Exam; Score: 215, August 25, 2016

Memberships:

• American Society of Clinical Oncology (ASCO) - 2022
• Turkish Society of Medical Oncology - 2020

EDUCATION:

• Turhan and Mediha Tansel Primary School (1979–1984)
• Kültür College (1984–1988)
• Semiha Şakir High School (1988–1991)
• Marmara University Faculty of Medicine (1991–1997)
• Marmara University Faculty of Medicine, Neurosurgery Department, Specialist Training (1997–2002)
• Title of Associate Professor in Neurosurgery (May 31, 2021)

ADDITIONAL TRAINING:

• "Visiting Physician," University of Southern California, Department of Neurosurgery (1998)
• "Microsurgery Training," GATA (Gülhane Military Medical Academy), Ankara Education and Research Hospital (2003)

PROFESSIONAL EXPERIENCE:

• Gülhane Military Medical Academy Haydarpaşa Training and Research Hospital (2002–2003)
• Dr. Lütfi Kırdar Kartal Training and Research Hospital (2003–2005)
• Private Avicenna Ataşehir Hospital (2005–2012)
• Private 29 Mayıs Hospital (2012–2013)
• Maltepe State Hospital (2013–2018)
• Kartal Dr. Lütfi Kırdar City Hospital (2018–2020)
• Private Academic Hospital (2020–2022)
• Hisar Intercontinental Hospital (2022–2024)
• Private Medipol Acıbadem Regional Hospital (2024–Present)

ADMINISTRATIVE AND ACADEMIC ROLES:

• Board Member, Neurosurgical Society (2006–2009)
• Head of the Emergency Department, Maltepe State Hospital (2014–2016)
• Deputy Chief Physician, Private Academic Hospital (2020–2021)
• Advisory Board Member, Beykent University Faculty of Medicine (2018–2024)
• Faculty Member, Galata University Faculty of Health Sciences (2022–2024)
• Director, Continuous Education Center, Galata University (2022–2024)

Dr. Ju-wan Seok is a neurosurgeon. He earned his M.D. from Hanyang University College of Medicine. He completed his internship and neurosurgery residency at Hanyang University Hospital. He later worked there as a neurosurgeon.

Dr. Seok is known for his innovative work. He won the 2017 contest for Making Ideas to Use Health Information Big Data. In 2016, he received the Best Fellow Award at Cheongdam Wooridul Spine Hospital.

Dr. Hilmi Apak is a respected pediatric hematology-oncology specialist with more than 21 years of experience. He is trained in pediatric oncology. Dr. Apak has led advanced treatments, including bone marrow transplantation, leukemia chemotherapy, and CAR T-cell therapy.

He has published 75 international medical articles, showing his strong contribution to pediatric oncology research. Dr. Apak has worked as assistant editor for the Turkish Pediatrics Archives Periodical. He has also held important academic and leadership positions, such as Head of Pediatric Hematology-Oncology at Istanbul University-Cerrahpaşa.

Education & Expertise

1995 to 2001 | Ege University Faculty of Medicine – Medical Education

2001 to 2006 | Dokuz Eylül University Faculty of Medicine – Internal Medicine Specialization

2008 to 2011 | Göztepe Training and Research Hospital – Gastroenterology Subspecialty

2014 | Ümraniye Training and Research Hospital – Associate Professor of Gastroenterology

2021 | University of Health Sciences – Professor

Professional Experience

2007 | Nusaybin State Hospital – Internal Medicine Specialist (Civil Service Obligation)

2011 to 2014 | Ümraniye Training and Research Hospital – Gastroenterology Specialist

2014 to 2017 | Ümraniye Training and Research Hospital – Associate Professor of Gastroenterology

2017 to 2021 | Health Sciences University – Associate Professor of Gastroenterology

2015 to 2021 | Ümraniye Training and Research Hospital Gastroenterology Clinic – Clinic Chief

2021 to 2022 | University of Health Sciences – Professor of Internal Medicine and Gastroenterology

2015 to 2022 | Genomic Laboratory (GLAB) Coordinator, Istanbul Provincial Health Directorate

2014 to 2021 | Northern Clinics of Istanbul Journal (indexed in WoS and PubMed) – Founding Editor

2021 to Present | Turkish Liver Research Association – Board Member

2022 to Present | Hepatology Bulletin Journal – Editor

2019 to Present | Hepatology Forum Magazine – Editor

2016 to Present | World Journal of Hepatology – Editor

International Experience

1999 | Trainee Doctor, Regional Infectious Diseases Unit, Western General Hospital, Edinburgh, UK

2000 | Trainee Doctor, Cardiology Unit, North Manchester General Hospital, Manchester, UK

2005 | Assistant Doctor, Regional Infectious Diseases Unit, Western General Hospital, Edinburgh, UK

Professional Memberships

Turkish Gastroenterology Association

Turkish Liver Research Association

EASL – European Association for the Study of Liver

APASL – Asian Pacific Association for the Study of Liver

AAAS – American Association for the Advancement of Science

Awards & Recognitions

2013 | Liver Fibrosis Pathways in Chronic Hepatitis B: A Comparative Proteomic Study – Gilead Fellowship Award

2014 | Liver Fibrosis Pathways in Chronic Hepatitis B: A Comparative Proteomic Study – Viral Hepatitis Fight Association Project Support Award

2014 | The Relationship between Spontaneous Seroconversion and Toll-Like Receptor Gene Polymorphism in Hepatitis B Infection – Turkish Gastroenterology Association, Best Poster Second Prize

2015 | Research on Damage Pathways in Liver Tissue in Chronic Hepatitis B: A Comparative Proteomic Study – Turkish Gastroenterology Association, Best Oral Presentation Third Prize

2016 | Investigations of the EGF and Its Receptor EGFR Gene Variants in Ulcerative Colitis – XV Euroasian Congress of Gastroenterology and Surgery, Best Oral Presentation Third Prize

Education & Expertise

• 1997 | Hacettepe University Faculty of Medicine – Medical Degree
• 2003 | Uludağ University Faculty of Medicine – Internal Medicine Specialization
• 2007 | Uludağ University Faculty of Medicine – Hematology Subspecialty

Professional Experience

• 1998 (May – September) | Practitioner, Dr. Salaha Health Center, Rize
• 1998 to 2003 | Research Assistant, Uludağ University Faculty of Medicine, Internal Medicine Department
• 2003 to 2007 | Hematology Subspecialist, Uludağ University Faculty of Medicine, Hematology Division
• 2007 to 2011 | Hematology Specialist, Bursa Ali Osman Sönmez Oncology Hospital (Compulsory Service)
• 2011 to 2013 | Hematology Specialist, Private Anadolu Health Center Bone Marrow Transplant Center, Gebze
• 2014 to 2015 | Assistant Professor, Yeditepe University Faculty of Medicine, Department of Internal Medicine
• 2015 to 2020 | Associate Professor, Yeditepe University Faculty of Medicine, Department of Internal Medicine
• 2020 to Present | Professor, Yeditepe University Faculty of Medicine, Department of Internal Medicine

Courses & Certifications

• Autologous and Allogeneic Stem Cell Transplantation Certificate
• Clinical Phytotherapy Application Certificate
• Flow Cytometry Experience Certificate
• EBMT Stem Cell Transplantation Course

Professional Memberships

• Turkish Medical Chamber
• Turkish Hematology Association (Full Member, No: 893)
• Turkish Therapeutic Apheresis Association (Current President)
• Geriatric Hematology Association
• Hematological Oncology Association
• EBMT (European Bone Marrow Transplantation)

Awards & Recognitions

• 2011 | 6th Turkish Therapeutic Apheresis Congress – Young Researcher Award

Education and Specialization

• 2006: Kocaeli University Faculty of Medicine
• 2014: Akdeniz University Faculty of Medicine, Internal Medicine
• 2018: Akdeniz University Faculty of Medicine, Medical Oncology

Experience

• 2006 - 2008: Konya Derebucak District Hospital
• 2009 - 2015: Akdeniz University Hospital
• 2015: Antalya Kaş State Hospital
• 2015 - 2016: İnönü University Faculty of Medicine
• 2016 - 2021: Akdeniz University Hospital
• 2021 - 2023: Antalya Training and Research Hospital

Education

GATA Faculty of Medicine, Doctor of Medicine Education, 1984, Ankara/Istanbul
GATA Faculty of Medicine, Neurology Residency, 1992, Ankara/Istanbul

Experience

GATA Neurology Department Specialization Student (1987-1992, Ankara/Turkey)
GATA Neurology Department Assistant Professor (1992-1995, Ankara/Turkey)
KüTahya Air Hospital Neurology Specialist and Chief Physician (1995-2003, Kütahya/Turkey)
Şişli Memorial Hospital Neurology Specialist (2004-2021, Istanbul/Turkey)

I completed my primary, secondary and high school education in Konya, my hometown, and my medical school and medical specialty education in Ankara GATA. I received flight medicine training and worked as a flight physician in the military and civilian sectors. I received beginner and advanced photography training and opened 4 photography exhibitions. I have made photography studies in 56 countries in Turkey and in 56 countries that I had the opportunity to visit.

Scientific Memberships

Turkish Medical Association
DGCA Health Board Membership

Education and Specialization

• 1982 - 1987: Ege University Faculty of Medicine
• 1987 - 1993: İzmir Atatürk Training and Research Hospital – Specialization

Experience

• 1993 - 1996: İzmir Atatürk State Hospital – Specialist Doctor
• 1996 - 1998: İnönü University Faculty of Medicine – Assistant Professor
• 1998 - 2001: İnönü University Faculty of Medicine – Associate Professor
• 2001 - 2005: Başkent University Adana Practice and Research Hospital – Associate Professor
• 2006 - 2007: Başkent University Adana Practice and Research Hospital – Professor
• 2007 - 2013: Başkent University Istanbul Practice and Research Hospital – Professor
• 2013 - 2015: Hisar Intercontinental Hospital, Istanbul – Professor
• 2015 - Present: Acıbadem Bakırköy Hospital, Istanbul – Professor