Sheba Pediatric CAR-T Program for Leukemia (ALL & AML) at Sheba Hospital- JCI accredited and Top-10 Hospitals 2026 by Newsweek
What's included in this package
Medical Procedures
- Complete blood count
- Biochemical blood analysis
- Consultation with a hematologist
- Extended analysis of blood
- Сonsultation with an oncohematologist
- Сomprehensive diagnosis of Leukemia
- CAR T-cell therapy
- 3 meals per day by nutritionist
- 24-hr nurse services
- Chest X-ray
- Anti-HIV test
- Anti-HBC test
- Anti-HCVAb test
- Echocardiography
- Consultation with an oncologist
- Consultation with a hematologist
- Consultation with an immunologist
- Consultation with a pediatric hematologist
- Consultation with a pediatrician
- Head MRI
- Color doppler echocardiography
- Complete blood count with cancer markers and a proteinogram
Duration
- 21 days in the hospital
Accommodation
Hospitalization
Transport
Transfer airport-hotel-airport
Additional information
Sheba Pediatric CAR-T Program for Leukemia (ALL & AML)
At Sheba Medical Center, children and young patients with leukemia have access to one of the most advanced and trusted CAR-T therapy programs in the world. The program specializes in treating acute lymphoblastic leukemia (ALL) and Acute Myeloid Leukemia (AML), including relapsed or treatment-resistant cases using highly personalized immunotherapy.
A Personalized Treatment Designed for Each Patient
CAR-T therapy uses the patient’s own immune system to recognize and destroy leukemia cells. This approach is especially important for patients who have not responded to standard treatments.
At Sheba, the entire process is performed on-site, ensuring speed and optimal quality:
Apheresis – collection of immune (T) cells
Cell Engineering – genetic modification at Sheba’s Advanced Biotherapy Center
Infusion – reintroduction of modified cells to target leukemia
Because no steps are outsourced, treatment can begin quickly and is typically completed within ~10 days. CAR-T acts as a “living therapy,” continuing to work in the body over time.
Expert Care in a Supportive Environment
Patients are treated by leading hemato-oncology specialists, under the supervision of Prof. Amos Toren, within dedicated CAR-T units.
The program provides:
Specialized pediatric and young adult CAR-T care with 24/7 monitoring
A multidisciplinary team (hematology, oncology, immunology)
A supportive, patient- and family-centered environment
Full international patient services, including travel and care coordination
Proven Outcomes and Global Leadership
Sheba is a global leader in CAR-T therapy, with strong clinical outcomes:
~90% remission in pediatric patients
~80% in young adults (up to 23 years)
~70% in adults
The program is experienced in treating complex and high-risk leukemia cases, offering options when other treatments are limited.
Comprehensive Evaluation and Ongoing Support
Each patient undergoes a full diagnostic work-up, including:
advanced imaging, bone marrow biopsy, genetic and molecular testing, as well as cardiac and pulmonary evaluation.
Care is provided in English, Russian, and Arabic, ensuring clear communication and continuous support for international families.
A Place Patients and Families Can Trust
By combining advanced science, rapid access to treatment, and compassionate care, Sheba offers one of the most trusted CAR-T programs for leukemia focused on achieving remission and helping patients return to a healthy, active life.
24/7 Bookimed assistance
- Personal medical coordinator
- Medical travel arrangements — booking of air tickets and hotel rooms at special partner prices
- Patient advocacy during medical travel
Program price
What's NOT included in this package
Doctor
Dr. Amos Toren is a pediatric hemato-oncologist at Sheba Medical Center. He served as Director of the Pediatric Hemato-Oncology and Bone Marrow Transplant Division. Dr. Toren holds a PhD in Human Genetics. He specializes in CAR T-cell therapy and bone marrow transplantation for children. Forbes Israel has recognized his expertise in hematology.
- Served as the Head of the Hematology Division at Tel Aviv University.
- Treats complex cases of leukemia, lymphoma, and rare pediatric cancers.
- Member of the American Society of Hematology and European Group for Blood and Marrow Transplantation.
- Collaborates on research with the NIH and St. Jude Children’s Research Hospital.
How are we doing?
About the clinic
Sheba Medical Center is the largest hospital in the Middle East and ranked 7th worldwide by Newsweek in 2026. It treats over 2 million patients annually and is a global leader in CAR-T and TIL immunotherapies. Core specialties include oncology, immunotherapy, precision medicine, and cardiology.
- JCI and ISO accredited with eight consecutive years in the Newsweek global Top 10.
- In-house CAR-T manufacturing through its GMP-certified Advanced Biotherapy Center (ABC).
- Over 200 Sheba doctors are listed among Forbes' Top Doctors.
- One of the few centers worldwide developing CAR-T therapies for severe autoimmune diseases.
- Campus includes six major hospitals, among them the Leviev Heart Center and Edmond and Lily Safra Children's Hospital.
Payment & Rewards
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