Pediatric Bone Marrow Transplant for Leukemia (ALL, AML, CML)
What's included in this package
Medical Procedures
- Biochemical blood analysis
- Bone marrow biopsy
- Complete blood count
- Consultation with a hematologist
- Cytogenetic study of the bone marrow
- Extended analysis of blood
- Сonsultation with an oncohematologist
- Сomprehensive diagnosis of Leukemia
- Anti-HIV test
- Anti-HBC test
- Anti-HCVAb test
- Blood tests
- Biochemistry blood test
- Biopsy
- Chest X-ray
- Complete blood count (CBC)
- Consultation with an immunologist
- Consultation with a cardiologist
- Consultation with a pediatric hematologist
- Consultation with a pediatrician
- Complete blood count with cancer markers and a proteinogram
- Electrocardiogram (ECG)
- Echocardiography
- Head MRI
- PET/CT
- Сonsultation with an oncohematologist
- 24-hr nurse services
- 3 meals per day by nutritionist
Duration
- 30 days in the hospital
Accommodation
Hospitalization
Transport
Transfer airport-clinic-airport
Additional information
Pediatric Bone Marrow Transplant for Leukemia (ALL, AML, CML)
Sheba Medical Center – Personalized, Advanced Care for Children
At Sheba Medical Center, we understand that a diagnosis of leukemia in a child changes everything for a family. Our Pediatric Bone Marrow Transplant (BMT) program is designed to provide not only world-class medical care, but also reassurance, compassion, and hope at every step.
As one of the leading pediatric transplant centers globally, Sheba combines decades of experience with cutting-edge therapies to treat children with acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and chronic myeloid leukemia (CML) especially in high-risk or relapsed cases where transplant offers the best chance for cure.
When is a Bone Marrow Transplant Needed?
For many children, leukemia can be successfully treated with chemotherapy. However, in certain situations such as relapse, resistance to treatment, or high-risk disease, a bone marrow transplant becomes the most effective path forward.
A transplant replaces the child’s diseased bone marrow with healthy stem cells, allowing a new, functioning immune system to develop and fight the cancer.
A Personalized Approach to Every Child
No two children are the same and neither are their treatments. At Sheba, every case is carefully evaluated by a multidisciplinary team of pediatric hemato-oncology and transplant experts to determine the optimal timing, donor source, and treatment strategy.
Whenever possible, a matched sibling donor is preferred.
If a sibling match is not available, Sheba actively secures the best possible alternative donor through advanced matching technologies and international registries. These include:
Matched unrelated donors from global donor programs
Haploidentical (partial match) family donors, such as parents
Cord blood transplants
Our advanced HLA and molecular laboratories enable precise donor matching, ensuring both safety and the highest likelihood of success.
Advanced Transplant Techniques
Sheba is recognized for applying the most advanced transplant methods available today, including:
T-cell depletion and CD34+ selection to reduce complications and improve outcomes
Integration of CAR-T cell therapy prior to transplant in selected high-risk leukemia cases
Access to innovative clinical trials and emerging therapies
These technologies allow us to safely perform transplants even in complex or previously untreatable situations.
World-Class Outcomes
Sheba’s Pediatric BMT program consistently achieves outcomes that meet or exceed international standards:
ALL & AML (first or second remission): ~70–85% success rates
Improved outcomes in relapsed cases through integration of advanced cellular therapies
Strong long-term survival and quality of life for pediatric patients
Our experience, combined with continuous research and innovation, allows us to offer children the best possible chance for cure.
Care Beyond Treatment
A bone marrow transplant is not just a procedure, it is a journey. At Sheba, children are cared for in dedicated, highly protected environments with advanced infection control, while families receive continuous guidance, emotional support, and clear communication throughout the process.
From diagnosis through recovery and long-term follow-up, our team remains closely involved—ensuring that each child not only overcomes the disease, but also returns to a healthy and fulfilling life.
Why Families Choose Sheba
Leading pediatric transplant center with global recognition
Expertise in complex and high-risk leukemia cases
Ability to secure suitable donors—even without a family match
Integration of CAR-T and advanced cellular therapies
Multidisciplinary, patient-centered care
Dedicated international patient services for a smooth experience
A Message of Hope
At Sheba Medical Center, we believe every child deserves access to the most advanced treatments available—delivered with compassion, precision, and unwavering commitment.
For children facing leukemia, bone marrow transplantation at Sheba is not just a treatment option—it is a pathway toward healing, recovery, and a brighter future.
24/7 Bookimed assistance
- Personal medical coordinator
- Medical travel arrangements — booking of air tickets and hotel rooms at special partner prices
- Patient advocacy during medical travel
Program price
What's NOT included in this package
Doctor
Prof. Amos Toren, MD, PhD, MHA, is a pediatric hemato-oncologist and BMT specialist. He served as Director of Pediatric Hemato-Oncology and BMT at Sheba Medical Center.
He is board certified in Pediatrics, Pediatric Hemato-Oncology, and Bone Marrow Transplantation. He holds a PhD in Human Genetics. He was Head of the Hematology Division at Tel Aviv University for two terms. He is a member of ASH, COG, ESPHI, EBMT, and CIBMTR. He also serves on the Ministry of Health Cord Blood Committee.
He led one of Israel’s most advanced pediatric oncology and BMT programs. The program treated children and young adults. His focus includes leukemia and lymphoma, immunodeficiencies, and rare cancers. He specializes in BMT and CAR T-cell therapy.
His translational research covers CAR T cells, cytokine-induced killer cells, pediatric brain tumors, and targeted therapies. He has worked with St. Anna, the NIH, and St. Jude. His publications include studies on pediatric SCT prophylaxis and PARP resistance.
How are we doing?
About the clinic
Sheba Medical Center, Israel’s leading hospital, is consistently ranked among the world’s top institutions. Treating over 2 million patients annually, Sheba combines world-class expertise with compassionate, personalized care. Its “City of Health” campus integrates six specialized hospitals, offering advanced treatments in oncology, neurology, cardiology, orthopedics, and more. Sheba is a global leader in CAR-T and TIL immunotherapies, precision medicine, and minimally invasive surgery, making it a trusted destination for international patients seeking cutting-edge healthcare.
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