Autologous Stem Cell Transplantation for Pediatric Osteosarcoma at Sheba Hospital- JCI accredited and Top-10 Hospitals 2026 by Newsweek
What's included in this package
Medical Procedures
- Consultation with an oncologist
- Bone marrow transplantation
- 3 meals per day by nutritionist
- 24-hr nurse services
- Electrocardiogram (ECG)
- Blood tests
- Chest X-ray
- Anti-HIV test
- Anti-HBC test
- Anti-HCVAb test
- Echocardiography
- Complete blood count (CBC)
- Biochemistry blood test
- PET/CT
- Consultation with an oncologist
- Consultation with a hematologist
- Consultation with an immunologist
- Consultation with a cardiologist
- Consultation with a pediatric hematologist
- Consultation with a pediatrician
- Сonsultation with an oncohematologist
- Head MRI
- Biopsy
- Computerized Bone Mineralometry (CBM)
- Complete blood count with cancer markers and a proteinogram
Duration
- 30 days in the hospital
Accommodation
Hospitalization
Transport
Transfer airport-clinic-airport
Additional information
Autologous Stem Cell Transplantation for Pediatric Osteosarcoma
Sheba Medical Center – Advanced, Personalized Care for Children
At Sheba Medical Center, we understand how challenging it can be for families to face a diagnosis of osteosarcoma. As the most common primary bone cancer in children and adolescents, osteosarcoma requires highly specialized treatment and close collaboration between pediatric oncologists, orthopedic surgeons, and transplant specialists.
While many children achieve excellent outcomes with a combination of chemotherapy and surgery, some cases require a more intensive treatment approach. For selected children with advanced, metastatic, or relapsed osteosarcoma, high-dose chemotherapy supported by Autologous Stem Cell Transplantation (ASCT) may offer an additional therapeutic option.
At Sheba, we combine world-class expertise, innovative treatment strategies, and compassionate family-centered care to provide every child with the most advanced treatment opportunities available.
When is Autologous Stem Cell Transplantation Considered?
Autologous Stem Cell Transplantation is not routinely used for all children with osteosarcoma. However, it may be considered in carefully selected situations, including:
Metastatic osteosarcoma
Relapsed disease
High-risk cases requiring intensified treatment
Children participating in specialized treatment protocols
In these situations, high-dose chemotherapy may be used to target resistant cancer cells. Stem cell transplantation allows doctors to safely administer these intensive treatments while supporting the body's recovery afterward.
How the Treatment Works
Stem Cell Collection
Before treatment begins, healthy blood-forming stem cells are collected from the child's bloodstream and carefully preserved.
High-Dose Chemotherapy
The child receives intensive chemotherapy designed to target remaining osteosarcoma cells throughout the body.
Stem Cell Rescue
After chemotherapy, the child's previously collected stem cells are reinfused to restore bone marrow function and support the recovery of healthy blood cells and the immune system.
This process allows physicians to deliver highly intensive treatment while helping the body recover efficiently.
Advanced Pediatric Sarcoma Care
At Sheba Medical Center, every treatment plan is tailored to the individual child.
Our multidisciplinary team integrates:
Pediatric oncology expertise
Advanced orthopedic oncology surgery
High-dose chemotherapy protocols
Stem cell transplantation when appropriate
Innovative supportive care strategies
This coordinated approach ensures that every child receives comprehensive care designed around their specific needs.
Specialized Pediatric Transplant Environment
Children undergoing stem cell transplantation are treated in dedicated pediatric transplant units designed specifically for safety, comfort, and healing.
Care includes:
Child-friendly treatment environments
Advanced infection prevention systems
Continuous monitoring by experienced pediatric specialists
Comprehensive supportive care throughout treatment and recovery
Every aspect of care is focused on helping children and families feel supported throughout their journey.
Clinical Expertise
Sheba Medical Center is internationally recognized for pediatric cancer care and stem cell transplantation, offering:
Extensive experience in treating complex pediatric solid tumors
Expertise in high-dose chemotherapy with stem cell support
Advanced multidisciplinary sarcoma care
Access to innovative treatment approaches and clinical research
Long-term follow-up focused on recovery, growth, and quality of life
Care That Supports the Whole Family
We understand that cancer treatment affects the entire family.
At Sheba, families are supported by a multidisciplinary team including physicians, nurses, psychologists, social workers, rehabilitation specialists, and care coordinators. From diagnosis through recovery, we provide guidance, reassurance, and ongoing support every step of the way.
Why Families Choose Sheba
Leading pediatric oncology and transplant center
Expertise in advanced osteosarcoma treatment
Experience with high-dose chemotherapy and stem cell support
Multidisciplinary care from internationally recognized specialists
Child-centered, family-focused approach
Dedicated international patient services
A Message of Hope
At Sheba Medical Center, we believe every child deserves access to the most advanced therapies available. Through innovative treatment strategies, specialized expertise, and compassionate care, we are committed to helping children with osteosarcoma achieve the best possible outcomes while supporting families with confidence, strength, and hope throughout their journey.
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- Personal medical coordinator
- Medical travel arrangements — booking of air tickets and hotel rooms at special partner prices
- Patient advocacy during medical travel
Program price
What's NOT included in this package
Doctor
Dr. Hana Golan, MD, heads the Pediatric Hemato-Oncology and Bone Marrow Transplantation (BMT) Division at Sheba Medical Center. She specializes in childhood cancers, with a focus on neuroblastoma and other high-risk solid tumors.
She leads one of the region’s most advanced pediatric oncology programs. She manages complex, high-risk cases and practices at a hospital ranked in the global top 10.
She is the principal investigator of the High-Risk Neuroblastoma ESIOP protocol. She serves as an investigator in international Phase I/II trials and as the national coordinator of multicenter oncology protocols. She led the development of computerized chemotherapy protocols and patient databases to improve safety.
She earned her MD from the Technion. She completed residencies in pediatrics and pediatric hemato-oncology at Sheba. She conducted advanced research in transplantation immunology at the Weizmann Institute. She is board-certified in Pediatrics and Pediatric Hematology-Oncology. She is a Senior Lecturer at the Sackler Faculty of Medicine, Tel Aviv University. Her research focuses on cancer stem cells, targeted therapies, treatment-resistant malignancies, and cannabinoid-related oncology.
How are we doing?
About the clinic
Sheba Medical Center is the largest hospital in the Middle East and one of the world’s leading medical institutions, consistently ranked among the global Top 10. Recognized by Newsweek and Statista for eight consecutive years, it ranked 7th worldwide in 2026. The hospital delivers comprehensive multidisciplinary care across all major specialties, including oncology, hematology, cardiology, neurology, and advanced surgery, treating over 2 million patients annually, including international cases. With more than 200 physicians listed among Forbes' Top Doctors, Sheba is a global leader in CAR-T and TIL immunotherapies, precision medicine, and minimally invasive surgery, making it a trusted destination for complex and advanced treatment.
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