Sheba Pediatric Personalized CAR-T Immunotherapy Program for Blood Cancers at JCI accredited and Top-10 Hospitals 2026 by Newsweek Hospital
What's included in this package
Medical Procedures
- CAR T-cell therapy
- 3 meals per day by nutritionist
- 24-hr nurse services
- CT Scan
- Electrocardiogram (ECG)
- Blood tests
- Chest X-ray
- Anti-HIV test
- Anti-HBC test
- Anti-HCVAb test
- Echocardiography
- Complete blood count (CBC)
- Biochemistry blood test
- Consultation with an oncologist
- Consultation with a hematologist
- Consultation with a pediatric hematologist
- Consultation with a pediatrician
- Сonsultation with an oncohematologist
- Head MRI
- Biopsy
- Complete blood count with cancer markers and a proteinogram
Duration
- 21 days in the hospital
Accommodation
Hospitalization
Transport
Transfer airport-hotel-airport
Additional information
Sheba Pediatric Personalized CAR-T Immunotherapy Program for Blood Cancers
At Sheba Medical Center, children and young patients receive some of the most advanced and compassionate cancer care available today. Sheba is a global leader in pediatric CAR-T cell therapy, offering highly personalized treatment for complex and resistant blood cancers, including:
• Acute lymphoblastic leukemia (ALL) and Acute Myeloid Leukemia (AML)
• Non-Hodgkin lymphomas (DLBCL, FL, MCL)
• Burkitt lymphoma
• CLL / Richter’s transformation
• Primary CNS lymphoma
• Multiple myeloma
A Gentle, Fully Integrated CAR-T Journey
Every step of the CAR-T process is performed on-site at Sheba, ensuring speed, safety, and the highest quality of care, especially important for children.
The treatment includes three carefully coordinated stages:
• Apheresis – collecting the child’s own immune (T) cells
• Cell Engineering – reprogramming the cells at Sheba’s Advanced Biotherapy Center
• Infusion – returning the cells to fight the cancer
Because everything is done within the hospital, treatment can begin quickly and is typically completed within ~10 days. CAR-T works as a “living therapy,” continuing to act in the body and offering the potential for long-term remission.
All patients are treated under the guidance of leading experts, including Prof. Amos Toren, with dedicated pediatric CAR-T teams ensuring continuous monitoring and care.
Designed Especially for Children and Families
Sheba understands that treating a child means caring for the entire family. The pediatric program offers:
• Specialized pediatric CAR-T units with 24/7 expert monitoring
• A multidisciplinary team of hemato-oncologists, immunologists, and pediatric specialists
• A supportive, child-friendly environment focused on comfort and safety
• Full international patient support, including travel and care coordination
Clinical Excellence You Can Trust
Sheba is one of the world’s leading centers in pediatric CAR-T, with strong clinical outcomes:
• ~90% remission in pediatric patients
• ~80% in young adults (up to 23 years)
• ~70% in adults
Importantly, Sheba offers flexibility in age criteria, ensuring that children and young patients can access advanced therapies when needed.
Comprehensive Care from Start to Finish
Each child receives a complete evaluation before treatment, including:
advanced imaging, bone marrow testing, genetic and molecular analysis, and full cardiac and pulmonary assessment.
Care is provided in English, Russian, and Arabic, helping families feel supported and informed throughout the entire journey.
Why Families Choose Sheba
By combining advanced science, speed, and deeply personalized care, Sheba provides one of the most trusted pediatric CAR-T programs in the world focused not only on treating disease, but on giving children the best possible chance to return to a healthy, active life.
24/7 Bookimed assistance
- Personal medical coordinator
- Medical travel arrangements — booking of air tickets and hotel rooms at special partner prices
- Patient advocacy during medical travel
Program price
What's NOT included in this package
Doctor
Prof. Amos Toren, MD, PhD, MHA, is a pediatric hemato-oncologist and BMT specialist. He served as Director of Pediatric Hemato-Oncology and BMT at Sheba Medical Center.
He is board certified in Pediatrics, Pediatric Hemato-Oncology, and Bone Marrow Transplantation. He holds a PhD in Human Genetics. He was Head of the Hematology Division at Tel Aviv University for two terms. He is a member of ASH, COG, ESPHI, EBMT, and CIBMTR. He also serves on the Ministry of Health Cord Blood Committee.
He led one of Israel’s most advanced pediatric oncology and BMT programs. The program treated children and young adults. His focus includes leukemia and lymphoma, immunodeficiencies, and rare cancers. He specializes in BMT and CAR T-cell therapy.
His translational research covers CAR T cells, cytokine-induced killer cells, pediatric brain tumors, and targeted therapies. He has worked with St. Anna, the NIH, and St. Jude. His publications include studies on pediatric SCT prophylaxis and PARP resistance.
How are we doing?
About the clinic
Sheba Medical Center is the largest hospital in the Middle East and one of the world’s leading medical institutions, consistently ranked among the global Top 10. Recognized by Newsweek and Statista for eight consecutive years, it ranked 7th worldwide in 2026. The hospital delivers comprehensive multidisciplinary care across all major specialties, including oncology, hematology, cardiology, neurology, and advanced surgery, treating over 2 million patients annually, including international cases. With more than 200 physicians listed among Forbes' Top Doctors, Sheba is a global leader in CAR-T and TIL immunotherapies, precision medicine, and minimally invasive surgery, making it a trusted destination for complex and advanced treatment.
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