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Spain, Seville

Alzheimer's disease Treatment in Centro de Neurología Avanzada (CNA)

About the clinic

Alzheimer’s disease care at Centro de Neurología Avanzada (CNA) in Seville, Spain, includes biomarker testing and treatment for early-stage disease. The center was an early provider in Spain of anti-amyloid therapies lecanemab and donanemab. Dr. Hernando Pérez Díaz specializes in dementia and cognitive disorders. He was named among Spain’s 50 best private-practice doctors in the Top Doctors Awards 2025.

Alzheimer’s diagnostic options

CNA’s Dementia Unit assesses cognitive decline using clinical, cognitive, blood, spinal fluid, and imaging tests. International patients can request videoconsultations for assessment and treatment planning.

  • Neurological consultation: Initial specialist assessment.
  • Blood biomarker tests: p-tau 217 testing and plasma screening for Alzheimer’s disease.
  • Cerebrospinal fluid study: Measures t-tau, p-tau, and beta-amyloid 42/40.
  • Imaging: PET amyloid imaging, brain MRI, advanced high-field MRI, and quantitative biomarkers of brain metabolism.
  • Cognitive assessment: Neuropsychological testing of thinking and memory.
  • ApoE genotype profiling: Genetic assessment used in treatment planning.

Alzheimer’s treatment options

Anti-amyloid medicines are considered for selected patients with early disease and confirmed amyloid pathology. Lecanemab is given through intravenous infusions, with clinical and MRI follow-up. Before treatment, the clinic assesses ApoE genotype and confirms amyloid using PET or cerebrospinal fluid biomarkers. The Clarity AD trial reported 27% slower cognitive decline versus placebo at 18 months.

  • Lecanemab: Anti-amyloid antibody for mild cognitive impairment or early Alzheimer’s with confirmed amyloid pathology.
  • Donanemab: Anti-amyloid antibody for prodromal or mild Alzheimer’s. It targets and reduces brain amyloid plaques, following specialist assessment and biomarker-based diagnosis.
  • Cognitive stimulation: Memory, attention, and language exercises that support cognitive reserve.
  • Transcranial magnetic stimulation: Non-invasive magnetic pulses that modulate neural circuits as an adjunct for cognitive symptoms.
  • Symptomatic drug treatment: Medicines to control symptoms and behavior in selected patients.
  • Vascular risk and lifestyle management: Support to control risk factors that can affect cognitive decline.
  • Neurological follow-up: Clinical and radiological monitoring of safety, disease course, and treatment response.

Patients can request a consultation through Bookimed to discuss assessment and treatment planning at CNA.

Highlights

20 doctors
35000 patients per year

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Centro de Neurología Avanzada (CNA)
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Treatments prices in the clinic

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Neurology
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Stereotaxic surgeries Price on request
Transcranial alternating current stimulation (tACS) Price on request
Spinal cord stimulator (SCS) Price on request

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Centro de Neurología Avanzada (CNA): more details about the clinic

Spain, Seville

Centro de Neurología Avanzada (CNA) is a private neurology center in Sevilla, Spain. The clinic operates across multiple sites and provides multidisciplinary care for adults and children. Its medical team includes 20 doctors who specialize in neurology, neurosurgery, and psychiatry. The Sevilla facility has nine consultation rooms and four waiting areas.

Key Statistics and Recognitions

The clinic treats roughly 35,000 patients every year. Within the dedicated Sleep Unit, specialists perform over 350 videopolysomnographic studies annually. CNA holds Top Doctors recognition for its high standard of private healthcare in Spain.

Several physicians have earned individual professional awards:

  • Dr. Hernando Pérez Díaz ranks among the 50 best doctors in Spain.
  • Dra. Iratxe Maestro received research awards from the Sociedad Andaluza de Epilepsia.
  • Dr. Pablo Clavel is recognized by Forbes as one of Spain's top 100 physicians.

CNA hosts epilepsy specialist rotations from Central America. The medical team also presents research at major events like the International Congress of Parkinson's Disease.

Neurological Care and Epilepsy Treatment

The clinic manages complex neurological conditions through specialized diagnostic and treatment pathways. The Epilepsy Unit uses prolonged video-EEG monitoring – up to 15 days – to identify seizure origins. This unit reports high surgical success rates:

  • Over 85% of patients with lesion-based epilepsy become seizure-free.
  • 84% of patients with mesial temporal sclerosis remain seizure-free after surgery.
  • 79% of temporal lobe epilepsy patients achieve total seizure control.

For neurodegenerative diseases, CNA offers an integrated cognitive decline assessment pathway. The team uses blood biomarkers and PET amyloid imaging to diagnose early-stage Alzheimer's disease. Selected patients may receive advanced anti-amyloid therapies like Donanemab or Lecanemab.

Advanced Neurosurgery and Spine Care

The neurosurgery department focuses on vascular pathologies and tumor removal. Surgeons perform wide craniotomies to treat giant meningiomas measuring up to 8 cm. They use intraoperative neurophysiological mapping to protect brain function during these procedures.

The Spine Unit specializes in minimally invasive techniques for degenerative disc lesions. Dr. Pablo Clavel leads the Artificial Disc Replacement (ADR) program with 25 years of experience. The clinic has performed over 2,500 spine operations. More than 90% of patients report pain reduction.

Psychiatry and Pediatric Services

The Psychiatry department treats adult conditions including depression, anxiety, and personality disorders. Specialists use transcranial magnetic stimulation to treat medication-resistant depression. This non-invasive method uses magnetic pulses delivered through a coil on the head to adjust neural circuits.

Pediatric care comes from the Neurodevelopment and Learning Disorders Unit. The team includes neuropediatricians, psychologists, and speech therapists who treat emotional and behavioral disorders. This unit integrates family and school settings into each child's treatment plan.

Diagnostic Technologies

CNA provides a full range of neurological testing tools. Specialists use high-resolution Doppler sonography to assess vascular risks in stroke patients. The facility also offers electromyography (EMG) and visual evoked potentials to test nerve and brain function.

The Sleep Unit features specialized equipment for sleep disorder check-ups. Spine surgeons use microsurgical vision systems and radioscopic guidance for precise implant placement. For complex epilepsy cases, the clinic uses Sentiva devices for vagus nerve stimulation.

International Patient Services

International patients can access videoconsultations to review medical results and plan treatment. These online sessions allow initial assessments without travel. Physical attendance is only needed for imaging or instrumental studies. CNA partners with Hospital Universitario San Rafael for specialized care needs.

Additional services
Language assistance
Available
free
Accommodation
Hotel (apartments) near the clinic, billed daily

Patient reviews

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10 Google reviews

Baldo Fernández

Oct 14, 2026
I had a polysomnography at CNA and all I can say is that the service and professionalism were excellent. Personalized care, very attentive staff, the standout was Lucia’s kindness and great work. Thank you very much.

manuel

Sep 18, 2026
Great professionals and good treatment, with follow-up regarding the illness. Going to the doctor Roshan’s consultation has been a real success—great professional.

Rosa Maria Cuervas Castrillo

Jul 20, 2026
We went to the CNA looking for a neurologist’s care so that my partner could be seen. We were attended to by Dr. Roshan Hariramani. We’ve been to two appointments and everything has gone very well. The doctor treated us with patience and gentleness.

Es 88

Jul 15, 2026
I want to thank Dr. Maestro Irache, the nurse Blanca, the TCAE Lucía, and the TCAE Inma for the very humane and professional treatment they gave me. They were unbelievably kind, attentive, and close at all times, making a difficult situation much easier to bear. You can tell they do their work out of true vocation and that they are fully trained to serve the public with empathy, respect, and professionalism. I only wish there were more healthcare professionals like them in our hospitals. My most sincere thanks for their dedication and for making patients feel heard, cared for, and treated with dignity. Thank you very much!

pepa garcia

Jul 15, 2026
Dr. Rodríguez Uranga is an excellent professional and a world-class reference epileptologist, who has managed to surround himself with an outstanding team of professionals. With his knowledge and efforts, through his work at the CNA Centers, he has managed to position Andalusia at the top of today’s modern Neurology landscape. For me, he is a true international benchmark. He also stands out for his empathy and involvement with his patients. Personally, I will be eternally grateful to him.

paco Gomez

Jul 14, 2026
Excellent treatment and great professionals. With the treatments provided, my improvement has only gone further, at an unbelievable pace. From here, I’d like to thank everyone for their dedication and commitment to finding the right solutions at every moment. Thank you again to all, from reception to the very last professional.

Susana muñoz

Jul 14, 2026
The best and most specialized center, magnificent professionals in all their specialties.
A very humane team.

Marina Núñez

Jul 14, 2026
The care I received from the entire team at CNA Sevilla was excellent. I was very well supported by the professionals throughout the whole treatment and afterward. Neurology, physiotherapists, psychology, and administration all got involved to look after me as well as possible, considering that I’m coming from Bcn—and what a great decision!

Rafael Dodero Sanchez

Mar 30, 2026
Thanks to everyone from Dr. Abril and all his team, I’m gradually learning more about my functional condition and we’re finding solutions for it. Everyone is very professional, and their empathy with patients is incredible.
Thank you

Sandra Rodriguez Garcia

Jan 15, 2026
I want to deeply thank the neurologist Juan M. Sánchez Caro for the care and dedication he provides to my father, who is ill with Parkinson’s. In a short time, he has developed delirium and psychotic outbreaks, and at all times the doctor is on top of things—responding to all our questions and adjusting the medication quickly and professionally. His closeness, availability, and humanity give us a lot of peace of mind in a very difficult moment. A great professional and a great person.
His professionalism and commitment
make all the difference. Totally recommended.

Av. Manuel Siurot, 43A, 41013 Sevilla, Spain

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Information was added by
Fahad Mawlood
Clinic’s representative
updated 11/5/2026

Get a free consultation

Centro de Neurología Avanzada (CNA)
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clock Average answering time – 5 minutes

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