Estophia Hospital exterior with city skyline, medical tourism project banner

Modern waiting area with indoor garden at Estophia Hospital, Istanbul

Patient room at Estophia Hospital with modern bed and comfortable seating

Modern waiting area at Estophia Hospital with stylish seating and glass partitions

Modern glass facade of Estophia Hospital in Turkey at dusk

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Turkey, Istanbul

Trans-sphenoidal hypophysectomy (adenomectomy) in Estophia Hospital

4.4

reviews

Doctor 4.4

Facilities 4.5

Staff 4.3

Language assistance 4.2

Support 4.6

77% Patients

recommended this clinic

About the clinic

Trans-sphenoidal hypophysectomy is a minimally invasive pituitary tumor surgery performed at Estophia Hospital in Istanbul, Turkey. The procedure may cost around $13,500 USD. The key advantage is the clinic's collective team experience, having performed over 800 similar surgeries.

The surgery is performed to remove a pituitary adenoma. This is a benign tumor at the base of the brain. The endoscopic trans-sphenoidal approach is used for precise, minimally invasive removal. This method helps address symptoms like visual impairment caused by the tumor pressing on the optic nerve.

This surgical package includes the use of a neuronavigator. This advanced imaging system guides the surgeon for greater accuracy. The entire treatment is conducted through the nose, avoiding any external incisions on the scalp or face. This leads to less visible scarring and a faster recovery for the patient.

What Is Included in the Package?

The quoted cost covers a comprehensive treatment plan. This includes:

Endoscopic sphenoidal pituitary adenoma surgery with neuronavigator guidance.
All related doctor and operating room fees.
A 3 to 4-day standard room hospitalization.
All necessary pre-operative laboratory tests and radiology.
Four days of post-operative follow-up care.
Transfer services between the airport, hotel, and hospital.

Treatment Timeline and Recovery

The total hospital stay typically lasts 3 to 4 days. Patients should plan to stay in the country for at least one week. This allows for a post-discharge control check before returning home. The package includes 4 days of immediate follow-up care after the surgery. Recovery varies for each individual based on their specific condition.

Additional Costs to Consider

Some essential services are not included in the main package price. Patients should budget separately for accommodation. Specialized consultations, such as with an endocrinologist or ophthalmologist, may cost around $125 USD each. A necessary pre-operative Brain MRI is also an additional cost, typically around $300 USD.

For a personalized cost estimate and to confirm the treatment plan, you can request a consultation via Bookimed.

Highlights

15 Year of foundation

87 doctors

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Accepted payment methods

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Treatments prices in the clinic

Last price update — 29.03.2025. Prices can be changed depending on the medical case and doctor's recommendations.

Neurosurgery

diagnostics	Price
CT (computer tomography)	$250 - $500
MRI of the spine cord	$250 - $1000
Revision of MRI results	Price on request
Consultation with creation of treatment plan	$115.73
Brain MRI with contrast (FLAIR sequence)	$300 - $500

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Licences

Notarized signature circular for Medical Promise Sağlık Turizmi Hizmetleri, Istanbul, 2019

Estophia Hospital : more details about the clinic

Turkey, Istanbul

Additional services

Transfer

Airport to clinic

free

Language assistance

Available

free

Accommodation

Hotel (apartments) near the clinic, billed daily

Patient reviews

Google 3.4

5 Google reviews

Ahmed Al-Akki

May 13, 2025

This hospital was first put into service in 1901, under the management of Dr. Vasil Dinov and Op. Dr. Garabet Yakubyan, with a capacity of 20 beds. In 1991, it continued to serve as Türkiye Gazetesi Hospital. I went to this hospital with my nephew to have his eyesight checked for a new eyeglasses prescription. The hospital looks very beautiful and historic. Also staff at the hospital were also very helpful. The whole process was smooth and fast.

Sarah Balter

Sep 29, 2025

For two years, I've suffered severe repeated and miserable respiratory illness with little respect from doctors. I went to Acibadem, and was treated like a cash cow - 9000tl for what? Fancy crown molding and designer entryways? I could not afford their basic consultation! With each visit, the price had only gone up while the quality of service dropped like a rock - more crowded, shorter appointments, overwhelmed staff. I was only spot treated and sent on my way, without spirometry or allergy testing, without education on my condition or even an official diagnosis. What doctor asks their patient if they want an allergy test!? How should I know? The gouging from Acidbadem, American, and Liv hospitals has been a common concern among myself and my friends. Even after I spent two nights at Acibadem because I could not breathe, my doc showed up for 20 seconds and left. She did not even speak to me. But my entire year of insurance coverage was blown. I tried state care as well, which I will not knock. Its amazing for broken arms, burns, stitches, immediate injuries. But the spirometry testing procedure was faulty and I was totally misdiagnosed. Turkiye Hastanesi, a private hospital, was like a breath of fresh air. My pulmonary/allergy doctor, Dr. Imran Ozdemir and the staff quickly and comfortably helped me identify that I have mild asthma, and that im allergic to all the grass and tree pollens. And the prices with insurance werent insulting or gouging, but very fair. Around 5000tl for a consult, testing and diagnosis, with MAPFRE insurance. 3600tl for an allergy test, a good price even though it was not covered. I know this is super expensive to Turks. But from my perspective as being from the US, access to healthcare like this for average Americans is literally unheard of and impossibly expensive. Tens of thousands of dollars. The campus is sprawling, green, and peaceful. It's cozy, and clean. And not at all pretentious. And I did not even have to ask for a woman translator. International guest services sent me Anna, immediately, and she was kind, professional, patient, and knowledgeable during both of my appointments. She even stepped in when another patient started randomly yelling at me. That woman seemed to think I had cut her in line, but I had shown her my number was next and she totally had a tantrum and started yelling and mocking me rudely with wildly inappropriate behavior. I spoke more than enough Turkish to set her straight, but Anna kept the situation calm and repeatedly informed the woman that hospital procedure was being followed, and redirected me to my appointment like a pro. And Hatice, who gave me my breath and allergy tests, has given me new faith and trust in medical services. Her dedication to a high standard of testing is a thing to behold. Im not exaggerating. After being misdiagnosed and neglected at other hospitals, it was her precision during our first breath test that led to an accurate diagnosis - only mild asthma, that can become risky when i have a virus or infection. And her allergy testing that sussed out that I'm allergic to tree and grass pollens. Finally an answer to my yearly miseries! Dr. Imran calmed my fears, prescribed me properly, and gave me actual guidance for lifestyle changes. And all were so kind and caring. This condition was seriously wrecking my quality of life. Thanks to Turkiye Hastanesi, I can get it back on track, and I have somewhere to go and a reliable doctor, if and when things get scary and i'm breathless again. That means a LOT. Will recommend to all my foreign colleagues.

BARTLOMIEJ BIALY

Aug 7, 2022

Super beautiful place and they have there great translator. His name is Erman, whenever you are going there call them and ask him to assist you. Very nice service, nice people in general.

Hleb Tsynkevich

Mar 29, 2025

This clinic failed to meet basic standards. I ended up with a staph infection after a hair transplant. All medical reports were provided, but I was ignored. Highly unprofessional and irresponsible.

Shamita Iyer

Jun 11, 2024

I had a great experience here. All the nurses and medical staff were really caring and took good care of me and fed me well. As a foreigner, it was nice that there was a hospital translator with me during my pre op checks.