Biopsy in Prime Fertility Clinic

An embryo biopsy for preimplantation genetic testing (PGT) at Prime Fertility Clinic in Bangkok, Thailand, identifies chromosomal abnormalities and hereditary disorders. The clinic is one of only six worldwide to hold JCI Ambulatory Care Accreditation. This diagnostic helps select embryos without detected genetic issues using Next Generation Sequencing (NGS) with a stated accuracy of 99.9%.

Testing Method and Process

The examination involves taking a sample from trophectoderm cells of a day 5 or day 6 blastocyst. A laboratory specialist extracts these cells to analyze the genetic makeup before any transfer occurs. The clinic uses NGS technology to evaluate all 23 pairs of chromosomes, including sex chromosomes.

• Blastocyst sampling. The specialist removes only a small number of cells from the outer layer of the embryo.
• NGS analysis. This technique checks all 46 chromosomes for abnormalities or hereditary conditions.
• Accredited laboratory. The facility holds ISO 15189 and ISO 15190 certifications for its lab standards.
• Selection criteria. Only embryos that do not show genetic disorders are chosen for the next steps.

Patient Indications

This diagnostic is typically recommended for patients with a history of two or more miscarriages before 12 weeks. It is also suitable for women aged 35 and older with medical indications. Couples who have experienced two consecutive failed assisted reproductive cycles often utilize this testing. Additionally, the clinic provides testicular sperm extraction (TESE) for severe male infertility cases to find viable sperm.

Quality and Standards

Prime Fertility Clinic is the third stand-alone fertility center in Thailand to achieve its specific international accreditations. While the testing evaluates sex chromosomes, gender selection is not allowed. All genetic diagnoses require a doctor's medical consideration based on the patient's history. Patients can request a consultation through Bookimed to discuss these diagnostic options.