


Bacillus Calmette-Guérin (BCG) therapy in Urologica Clinic
About the clinic
Bacillus Calmette-Guérin (BCG) therapy at Urologica Clinic in Istanbul, Turkey, is a specialized treatment for high-risk non-muscle invasive bladder cancer. This immunotherapy aims to prevent tumor recurrence and progression while preserving the bladder. The procedure is led by Prof. Dr. Özkan Onuk, a specialist with experience in over 3,000 surgeries and certification from the Rigicon Global Reference Center.
Advanced Bladder Cancer Care
Urologica Clinic holds JCI and ISO 9001 accreditations, meeting high international safety standards. The medical team follows a bladder-sparing approach for patients who have already undergone a transurethral resection of bladder tumor (TURBT). This method helps many patients avoid radical surgery and keeps the bladder functional. A multidisciplinary oncology team coordinates every step from the initial diagnosis through long-term follow-up care.
How BCG Therapy Works
The clinic uses an intravesical immunotherapy protocol. This means the doctor places the BCG agent directly into the bladder using a small catheter. The agent is a weakened form of Mycobacterium bovis. It works by stimulating the body's immune system to attack and destroy any remaining tumor cells. The treatment protocol typically includes:
- Induction phase: One dose per week for 6 weeks.
- Maintenance phase: Regular doses over 1 to 3 years to maintain the immune response.
- Monitoring: Regular cystoscopy exams and imaging to track the health of the bladder lining.
Expertise of Prof. Dr. Özkan Onuk
Prof. Dr. Özkan Onuk serves as the Clinical Director at Urologica Clinic and is a faculty member at Biruni University. He has performed over 3,000 procedures and brings over 15 years of experience to the urology department. As an active member of the European Association of Urology (EAU) and the International Society for Sexual Medicine (ISSM), he applies international protocols to bladder cancer care. His expertise helps manage side effects, which are usually mild and may include temporary urinary frequency or flu-like symptoms.
To learn more about your treatment options or to discuss your case with the medical team, you can leave a request on Bookimed.
Highlights
Get a free consultation

Treatments prices in the clinic
| treatment | Price | |
|---|---|---|
| Transurethral resection of the bladder | Price on request | |
| Transurethral incision of the prostate (TUIP) | Price on request | |
| Testicular prosthesis | Price on request | |
| Laparoscopic nephrectomy | Price on request | |
| Prostatectomy | Price on request | |
| Nephrectomy | Price on request | |
| Da Vinci Robotic System | Price on request | |
| Transurethral resection of the prostate (TURP) | Price on request | |
| Robotic da Vinci prostatectomy | Price on request | |
| Cryodestruction | Price on request | |
| Bacillus Calmette-Guérin (BCG) therapy | Price on request | |
| Cryotherapy | Price on request | |
| Cryotherapy for kidney cancer | Price on request | |
| Bladder removal with reconstruction | Price on request |
How are we doing?
hospital accreditations of quality
Urologica Clinic: more details about the clinic
Clinic Achievements and Safety Standards
The clinic reports 3,000+ successful surgeries and treats over 5,000 patients. It maintains a 98% patient satisfaction rate. Urologica holds several international quality certifications:
- JCI accreditation
- ISO 9001 and ISO 27001 certifications
- Rigicon Global Reference Center designation
- FDA-approved surgical products
Prof. Dr. Özkan Onuk is a member of the European Association of Urology (EAU) and the International Society for Sexual Medicine (ISSM).
Urological Oncology and Kidney Cancer Care
The oncology department treats kidney, bladder, and prostate cancers. For kidney cancer, the clinic reports a 90% cure rate for early-stage (T1–T2) tumors. Surgeons perform partial nephrectomy to spare healthy tissue when possible.
Treatment follows a multidisciplinary approach. The surgical team coordinates with medical oncology, radiation oncology, and pathology specialists. Kidney cancer patients typically stay 3–5 days. Full return to normal activities usually takes 4–6 weeks.
For bladder cancer, the clinic offers several diagnostic and therapeutic procedures:
- TURBT (transurethral resection of bladder tumor)
- Fluorescence cystoscopy for precise tumor detection
- Radical cystectomy for muscle-invasive disease
- Intravesical chemotherapy and BCG therapy
Advanced imaging supports diagnostic accuracy. The clinic uses MR-fusion biopsy for prostate cancer. This technology combines MRI scans with real-time ultrasound for precise tissue sampling.
Male Sexual Health and BPH Treatments
Urologica specializes in treating erectile dysfunction and Benign Prostatic Hyperplasia (BPH). The clinic uses HoLEP technology for enlarged prostates of all sizes. This holmium laser technique separates the adenoma from the capsule without external incisions.
HoLEP requires just 1–2 days in hospital. The clinic reports a recurrence risk below 1%. Other BPH options include GreenLight laser vaporization and TURP.
For male sexual health, the clinic specializes in 3-piece inflatable penile implants. These implants provide a natural appearance and sensation. Brands include Boston Scientific, Coloplast, and Rigicon. A four-stage recovery plan guides patients from surgery to implant activation at 6 weeks.
Technologies and Diagnostic Equipment
The surgical suites support robotic, laparoscopic, and endoscopic procedures. The team uses the Da Vinci Robotic System for complex urological surgeries. This allows smaller incisions and faster recovery.
Diagnostic capabilities include:
- Urodynamics to assess bladder and urethral function
- Color Doppler ultrasound of the scrotum
- Transrectal ultrasonography (TRUS)
- Narrow band imaging (NBI) for cystoscopy
The clinic also offers non-surgical therapies. These include P-Shot (Priapus Shot) and shock wave therapy (ESWT) for vascular-related erectile dysfunction.
International Patient Services
Urologica provides structured support for patients traveling from abroad. Staff coordinate airport transfers and hotel accommodations. Language support is available in English and Arabic.
International patients receive remote follow-up to monitor recovery after returning home. The clinic offers free pre-evaluation via WhatsApp, so specialists can review medical history before travel. Follow-up check-ups are scheduled at 1 month, 3 months, and 1 year.
Additional services
Patient reviews
emre erdinc
Beşaltı Mobilya
Ünal GÜVENÇ
Fuzail Majoo
Bilgin Göçmen
Nura Nura
Abdullah Bektas
Zeytinburnu Çilingir Baş çilingir
ŞEVKET CEKİN
Maltepe, Yedikule Çırpıcı Yolu 1İ, 34010 Zeytinburnu/İstanbul, Türkiye
Get a free consultation

How it works:
- We find a medical coordinator familiar with the matter
- You get a personal offer with a step-by-step guide and the cost estimate
- We arrange your travel including appointment scheduling and flights booking
- You arrive at the hospital, we support you 24/7
