Knee replacement in Italy | Cost ▷ TOP 10+ Clinics 2026

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How Much Does Knee replacement Cost in Italy?

The average cost of Knee replacement in Italy ranges _prices_. The offers include knee replacement or arthroplasty, consultation with an orthopedist, hospitalization, language assistance, a 4-star hotel, and sports prosthetics for above or below the knee.

Key Benefits

Why do patients choose Italy for knee replacement?

Accredited clinics: JCI-certified hospitals ensure high standards of care and patient safety.
Latest technologies: The NAVIO robotic system is used to enhance precision in knee surgeries. This approach helps reduce pain, shortens recovery time, and minimizes complications.
High success rates: Knee replacement procedures in Italy have an efficacy rate of 90-95%. This ensures improved joint function for various patient conditions.
Expert surgeons: Renowned specialists such as Dr. Roberto D’Anchise have extensive experience in knee surgery. They perform numerous procedures annually and hold comprehensive certifications.

Access advanced Knee replacement solutions in trusted clinics from $27,196.

	Italy	Turkey	Austria
Knee replacement	-	from $6,500	from $20,000
Unicompartmental (partial) knee replacement	-	from $3,500	from $14,000
Total knee replacement (arthroplasty) revision	-	from $6,973	from $27,000
Total knee replacement (TKR) with OMNI	-	from $8,500	from $25,000
Revision knee arthroplasty	-	from $9,900	from $30,000

Data verified by Bookimed as of March 2026, based on patient requests and official quotes from 232 clinics worldwide. Median costs are based on real invoices (2024–2026) and updated monthly. Actual prices may vary.

Knee replacement Packages in Italy — March 2026

Procedure type

IRCCS OSPEDALE GALEAZZI - SANT'AMBROGIO

Roberto Danchise

53 years of experience

This package uses Zimmer Biomet implants within Italy's leading orthopedic hospital, which performs 75% of the nation's complex revision surgeries with a 91% success rate. Dr. Roberto Danchise, who performed Italy's first meniscus transplant and has completed over 2,100 knee replacements, leads the procedure at the ISO-accredited IRCCS OSPEDALE GALEAZZI - SANT'AMBROGIO. The cost of approximately $27,196 includes the implant, surgery, and 6 days of hospitalization at a facility conducting 5,000 orthopedic operations yearly, which also houses the RE.GA.IN regenerative institute for advanced stem cell therapies.

Discover the Best Knee replacement Clinics in Italy: 8 Verified Options and Prices

The Bookimed clinic ranking is based on data science algorithms, providing a trusted, transparent, and objective comparison. It takes into account patient demand, review scores (both positive and negative), the frequency of updates to treatment options and prices, response speed, and clinic certifications.

San Donato Hospital

Italy, Milan

Clinic is certified :

Policlinico San Donato in Milan offers online knee replacement consultations for around $410, typically covering the orthopedist's evaluation. The hospital holds Scientific Institute for Research and Healthcare Accreditation and maintains a 4.7/5 rating from patient reviews. Initial assessments require medical reports and imaging in DICOM format, allowing remote evaluation without travel to Italy.

diagnostics
MRI of one area	$302.18 - $534.63

San Raffaele

Italy, Milan

Clinic is certified :

San Raffaele Hospital performs over 52,000 surgeries annually, including knee replacements, at one of Europe's largest research hospitals with specialized orthopedic capabilities.

diagnostics
Scintigraphy	$348.67
MRI of one area	$617.15

Ospedale San Carlo di Nancy

Italy, Rome

Clinic is certified :

Ospedale San Carlo di Nancy is the only Italian hospital designated a national reference for robotic knee replacement using NAVIO system. Their all-inclusive package typically covers the surgical procedure, suite room accommodation, meals, and companion stay. As part of the GVM Care & Research network, the clinic ensures high standards of care with NAVIO robotic technology for precise implant positioning.

treatment
Knee replacement	$23,244.72 - $29,055.9

Maria Cecilia Hospital

Italy, Bologna

Raul Zini

47 years of experience

Clinic is certified :

Maria Cecilia Hospital features Dr. Raul Zini, who has performed 15,000+ orthopedic operations and specializes in advanced knee replacement techniques. The clinic handles over 1,200 orthopedic cases annually with a dedicated team focusing on joint reconstruction and prosthetic surgery.

Price on request

Mater Oblia Hospital

Italy, Rome

Vincenzo De Santis

26 years of experience

Mater Olbia Hospital specializes in knee replacement with robotic-assisted techniques. Dr. Vincenzo De Santis, Director of Orthopedics, has performed over 5,500 surgical procedures, including 2,500+ as lead surgeon in joint replacements. The procedure typically runs $13,600–$24,000. The hospital combines expertise from Qatar Foundation Endowment and Fondazione Policlinico Universitario Agostino Gemelli IRCCS.

Price on request

Knee replacement in Italy: Your Travel Plan

Day 1: Arrival in Italy

You should arrive at the airport in Italy with all necessary documents, including your passport and medical records.
Arrange transportation to your accommodation. Ensure it is close to the hospital where your knee replacement is scheduled.
Rest and acclimate to the time zone to prepare for upcoming medical appointments and procedures.

Day 2: Pre-operative Consultation and Evaluation

You need to attend a pre-operative consultation at the hospital. Share all necessary imaging (MRI, CT SCAN) in DICOM format and medical reports as previously requested via platforms like wetransfer.com.
Discuss your medical case and treatment plan. Consider using the second opinion service and online consultation if not already done. Finalize any last-minute details with the specialist, possibly Dr. D’Anchise if you opted for Galeazzi Hospital.
Undergo any additional diagnostics if required, such as blood tests or physical evaluations.
Receive detailed instructions on pre-surgery preparation, including fasting requirements and medication guidelines.

Day 3: Rest and Preparation

You should follow any dietary restrictions or medication protocols as advised by the medical team.
Ensure you have comfortable clothing and necessary personal items packed for the hospital stay.
Stay hydrated and get plenty of rest to ensure your body is in optimal condition for the surgery.

Day 4: Surgery Day

You need to arrive at the hospital at the designated time, typically early morning, for the knee replacement surgery.
The procedure may involve advanced technology such as the NAVIO robotic system, known for reducing pain and ensuring better joint movement.
Expect to spend several hours in surgery and recovery, monitored by medical staff.
Post-surgery, you may be transferred to a suite room where a companion can stay with you, as some hospitals include this in their package.

Day 5-7: Hospital Recovery

You will receive medical and nursing assistance as you begin the initial recovery phase in the hospital.
Engage in light physical therapy exercises to promote joint movement and prevent stiffness.
Follow a prescribed pain management regimen to manage post-operative discomfort.
Communicate any concerns or complications to the medical team immediately.

Day 8-10: Discharge and Initial Home Recovery

Upon discharge, receive detailed instructions for home recovery, including physical therapy exercises and medication schedules.
Arrange transportation back to your accommodation. Ensure you have assistance if needed due to mobility limitations.
Continue prescribed exercises and follow up on any scheduled outpatient appointments or consultations.
Maintain open communication with the clinic for any questions or concerns during this phase.

Day 11-14: Continued Recovery and Follow-up

You should focus on gradually increasing mobility and strength through continued physical therapy.
Attend any follow-up appointments or virtual consultations to monitor progress and adjust treatment plans as necessary.
Ensure you adhere to dietary and lifestyle recommendations to support healing and overall health.
Prepare for your return journey home, considering any travel restrictions or medical advice regarding flying post-surgery.

Day 15: Return Home

Ensure you have all necessary documentation and medical records for your return journey.
Arrange for assistance at the airport if mobility is still limited.
Once home, continue with prescribed rehabilitation and maintain communication with your local healthcare provider for ongoing recovery support.
Contact the clinic in Italy if any post-operative issues arise or if further consultation is needed.

Our Doctors

View all Doctors

Roberto Danchise

53 years of experience

Performed Italy's first meniscus transplant – Dr. Danchise specializes in advanced knee procedures at IRCCS Ospedale Galeazzi.

Trained in knee replacement in London and New York
Specialized in orthopedics and traumatology at University of Milan
Chair of the Italian Society for Knee Surgery
Member of multiple international orthopedic associations

Raul Zini

47 years of experience

15,000+ surgeries performed – Dr. Zini specializes in knee replacements and sports-related orthopedic conditions at Maria Cecilia Hospital.

1,215 hip arthroscopies between 2009 and 2015
Coordinator of Orthopedics and Traumatology since 2007
Treated many professional athletes including Sasha Djordjevic
Author of 100+ publications in orthopedic research
Twice awarded the Bellando-Randone Prize for best monographs

Vincenzo De Santis

26 years of experience

Dr. Vincenzo De Santis is the Director of the Orthopedics and Traumatology Complex Operational Unit at Mater Olbia Hospital. He earned his medical degree and a PhD in experimental methodologies and technological applications in Angiology, Vascular Surgery, and Orthopedics from Università Cattolica del Sacro Cuore in Rome.

Dr. De Santis focuses on hip and knee prosthetic surgery, sports traumatology, and arthroscopic knee surgery. He is also skilled in computer-assisted and robotic surgery. He has performed over 5,500 surgical procedures. In more than 2,500 of these, he served as the lead surgeon. This experience shows his strong expertise in both elective orthopedic and trauma surgery.

Since 2009, Dr. De Santis has been involved in academic teaching. He has contributed to orthopedic education at Università Cattolica del Sacro Cuore.

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Written by Kateryna Zamkovska

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Updated: 10/20/2022

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This page may feature information relating to various medical conditions, treatments, and healthcare services available in different countries. Please be advised that the content is provided for informational purposes only and should not be construed as medical advice or guidance. Please consult with your doctor or a qualified medical professional before starting or changing medical treatment.

Our Knee replacement Techniques: What Suits You Best?

When considering Knee replacement, it’s important to understand the different techniques and which is best suited for you. Here’s a concise comparison of popular options:

Knee Arthroscopy

A minimally invasive surgical procedure used to diagnose and treat problems in the knee joint by inserting a small camera and instruments through tiny incisions.

Pros: Offers quicker recovery times than open surgery, with fewer complications. Studies show up to 80% success in treating meniscal tears.

Cons: Limited to minor repairs and may not address severe arthritis. There's a 10-20% chance of needing further surgery.

Effectiveness: Effective in 70-90% of cases for relieving pain and improving function.

Duration: 1-2 hours

Recovery: 1-6 weeks

Best for: Meniscal tears, loose fragments, and mild to moderate cartilage damage.

Prices: Cost of Knee Arthroscopy in Italy from $1,800

Unicompartmental (partial) knee replacement

This procedure involves replacing only one compartment of the knee joint, preserving more of the patient's natural bone and ligaments.

Pros: Retains more natural knee function with 85% of patients reporting a more natural feel compared to total knee replacement. Smaller incision results in quicker recovery.

Cons: Not suitable for patients with severe arthritis affecting multiple compartments. Revision rate is higher, with about 10% needing further surgery within 10 years.

Effectiveness: 10-year survival rate is approximately 85%.

Duration: 1-2 hours.

Recovery: 3-6 months.

Best for: Patients with arthritis confined to a single knee compartment. Ideal for those under 60 years old.

Prices: Cost of Unicompartmental (partial) knee replacement in Italy from $3,500

Knee MAKOplasty

Knee MAKOplasty is a minimally invasive knee surgery using robotic assistance to ensure precise implant placement.

Pros: Provides more precision than traditional knee surgery, with a 90% success rate in pain reduction. Minimally invasive, leading to smaller incisions and less scarring.

Cons: Requires specialized equipment and training, which may not be available in all facilities. Longer learning curve for surgeons compared to traditional methods.

Effectiveness: 98% accuracy in implant positioning, enhancing joint function and longevity.

Duration: 2-3 hours

Recovery: 4-6 weeks

Best for: Patients with osteoarthritis affecting one or two knee compartments. Suitable for individuals seeking faster recovery.

Prices: Cost of Knee MAKOplasty in Italy from $14,500