Page 8 - Best Doctors in Spain — Get an Online Consultation

Dr. César Lévano Linares is a specialist in general and digestive surgery. He works at Rey Juan Carlos University Hospital and Fundación Jiménez Díaz University Hospital. He is recognized for his work in laparoscopic colorectal surgery.

He holds a PhD in Medicine and Surgery from the Autonomous University of Madrid. He completed a master’s in colorectal and pelvic floor surgery at the University of Zaragoza. He also holds a diploma in laparoscopic surgery from Louis Pasteur University in Strasbourg. He has European accreditation in laparoscopic surgery (EACCME).

His research covers bilateral retroperitoneal hibernoma and conversion from primary endoluminal endoscopic surgery to laparoscopic gastric bypass.

Dr Casado Morente is a permanent member of the Spanish Otorhinolaryngology Society and Cervical-Facial Pathology, as well as being a member of the Committee for the revision of scientific articles of said society. Since 2013 he has been the Co-Director of the Otorhinolaryngology Unit of the Quirónsalud Marbella Hospital.

He is a prestigious specialist of reference in the field of voice pitch change (voice feminisation and masculinisation). He is a frequent participant in a number of congresses as a speaker, national and international courses, as well as producing numerous reports in congresses.

Professional Experience

• Head of the Otorhinolaryngology Unit at the Quirónsalud MarbellaHospital.

• Head of the Otorhinolaryngology Unit at the Quirónsalud Campo de Gibraltar Hospital.

• Member of the Committee for the revision of scientific articles of the Spanish Otorhinolaryngology Society (SEORL in its Spanish abbreviation) and Cervical-Facial Pathology (PCF in its Spanish abbreviation).

• President of the Commission of Laryngology ,Voice and Deglutition of the Spanish Otorhinolaryngology Society (SEORL, in its Spanish abbreviation) and Cervical-Facial Pathology (PCF in its Spanish abbreviation).

• Professor of the University Official Master Degree "Voice and Language Disorders at the Catholic University of Murcia (UCAM in its Spanish abbreviation).

• Honorary Cooperating Lecturer at the Malaga University (UMA, in its Spanish abbreviation).

• Vice-president of the Costa del Sol International Medical Academy (IMA, in its Spanish abbreviation).

• Founding Member of the International Association of Trans Voice Surgeons (IATVS) in Berlin, 2022 (jointly with 8 other surgeons from other parts of the world who specialise in voice pitch change: voice feminisation and masculinisation.

Book Publications:

• Clinical Assessment of the Voice. Medical and Speech Therapy Fundamentals. Authors: Juan Carlos Casado and José Antonio Adrián.

• Manual for the Laryngectomised Patient. Authors: Juan Carlos Casado Morente and José Antonio Adrián Torres

• Voice Disorders. From Diagnosis to Treatment. Authors: Juan Carlos Casado Morente and Agustín Pérez Izquierdo

• Voice Feminisation. A Mutidisciplinary Approach in Transgender Women. Authors: Juan Carlos Casado Morente and Enrique Maraví Aznar.

Otorhinolaryngology (ENT) and head and neck surgery are a medico-surgical speciality dealing with the study, diagnosis and treatment of the pathologies affecting the ear (hearing and balance), the upper airways (nose, paranasal sinuses, pharynx and larynx), sense of smell, oral cavity, neck and salivary glands.

The ENT Unit of Quirónsalud Marbella Hospital comprises a team of outstanding specialists in this medical field, who are a reference at national and international level, on account of their research work, implementation and development of avant-garde techniques, as well as regular publications in highly-influential scientific journals.

An expert in microbial resistance and optimisation of the use of antimicrobials, he leads the Infectious Disease Unit of this hospital in Malaga.

Dr Javier Moreno Izarra is habitually involved in national and international scientific events. At the same time, he gives presentations that are specially focused on infectious disease in the area of antimicrobial resistance and in medical forums dedicated to the development of programs to optimise the use of antimicrobials.

Professional Experience:

• Head of the Internal Medicine Unit. Quirónsalud Marbella Hospital

• Head of the Internal Medicine Unit. Quirón Campo de Gibraltar Hospital

• Specialist of the Internal Medicine Unit. Alto Guadalquivir Hospital

• Specialist of the Internal Medicine Unit. Andújar Hospital

• Medical Coordination of the A&E Unit and Hospitalisation. High- resolution Hospital in Puente Genil

• Specialist of the Internal Medicine Unit. Costa del Sol Hospital

A member of:

• Spanish Society of Internal Medicine

• Spanish Society of Infectious Disease and Clinical Microbiology

• Spanish Society of Palliative Care

The Internal Medicine speciality is a branch of medicine that focuses on the diagnosis, treatment and prevention of diseases and conditions of adult patients. Internists of the Quirónsalud Marbella Hospital are experts in the comprehensive health care of their patients as they manage a broad range of medical conditions. The team of specialists of our Marbella hospital stands out for its comp rehensive approach and deep knowledge and skills relating to chronic disease. Their objective is to provide a high-quality medical service while guiding the patient and coordinating the actions against their diseases in close cooperation with the other specialists, if necessary, in order to obtain an adequate diagnosis and treatment. One fundamental part of the work of an internist is the management of chronical diseases such as diabetes, hypertension, heart and lung disease, amongst others.

These conditions often require follow-ups and adjustments to the treatment throughout time.

The Internal Medicine team does not only focus on the treatment of diseases, but also on their prevention. Internists work with their patients to identify the risk factors and promote healthy habits. 

With a Degree in Medicine obtained at the Granada University, he is the author of three books entitled: “Electrocardiography for Residents”, “Urgencies Manual” and “Protocol for Infectious Endocarditis”.

Additionally, he has written over 80 publications for conferences, including price-awarded “Ischaemic Cardiopathy in Women” and “Refractory Angina”.

Dr Said Barakat is considered to be a reference in cardiology in the Andalusian region. Additionally, he has been designated as the Head of the Diplomatic Corps and the Community of Saudi Arabia in health matters by the Embassy of said country in Malaga.

Professional Experience

Over 15-years' experience

• Head of the Unit and Head of the Clinical and Supplementary Tests
• Area of Quirón Marbella Hospital (2003 - currently).
• Head of the Diplomatic Corps and the Saudi Arabia Community appointed by the Embassy of said country in Malaga.
• Head of the Neumopac (Functional Respiratory Tests) Unit.
• Head of the Nuclear Cardiology Unit of the Tanit Institute in Malaga.
• University Degree in Medicine at the Granada University.
• Resident Doctor in Cardiology at the Carlos Haya Hospital in Malaga.

The Cardiology Unit of Quirónsalud Marbella Hospital is made up of a medical team with large experience in the diagnosis and treatment of heart diseases, as well as employing the most advanced technologies, both in the clinical area and in the area of haemodynamics and arrhythmia.

Diseases, treatments and techniques:

Clinical cardiology

- Adult and children cardiology consultation with the performance of supplementary tests, all within one appointment.

- Specific consultations for arrhythmia

- Paedriatic cardiology

- Colour Doppler echocardiography and stress echocardiography

- Stress test

- 24-hour and long-term Holter EKG

- CT coronary angiogram

- Cardiac magnetic resonance imaging (MRI)

- Tilt table testing

- Cardiac rehabilitation

Cardiac haemodynamics

- Diagnostic cardiac catheterisation and percutaneous treatment of ischaemic heart disease with angioplasty and stent implant

- Myocardial infarction percutaneous treatment programme

- Transcatheter aortic valve implantation (TAVI)

- Percutaneous repair of the mitral valve (Mitral clip)

- Percutaneous closure of interatrial communication

- Percutaneous closure of left atrial appendage

Arrhythmia Unit  

- Diagnostic electrophysiological study  

- Catheter ablation

- Cryoablation of atrial fibrillation

- Ablation using a complex arrhythmic substrate navigator

- Pacemaker implantation  

- Automatic endovenous and subcutaneous implantable defibrillator

Cardiac surgery  

- Surgery with and without extracorporeal circulation

- Minimally-invasive surgery with an early extubation

- Repair of mitral and aortic valves

His extensive training includes qualifications that award him the specialisation in endovascular techniques relating to angiology, such as the certification to manage vascular laboratories and X- ray facilities with medical purposes granted by the Medical Physics Spanish Association, as well as numerous training positions in national and international medical centres and hospitals in France, the UK and the USA.

Dr Gallardo Pedrajas combines his medical practice with his teaching position as an Assistant in the Surgery Studies of the Malaga University and the European Society of Vascular Surgery (ESVS). He is also very active as a scientific researcher and proponent, with numerous research papers and projects being published in scientific journals of international reputation, and has been involved in more than 100 medical lectures and communications within his specialisation.

Professional experience

• Medical Residency in Angiology and Vascular Surgery, A Coruña University Hospital.( 2007-12).

• Consultant Doctor in Medicine, Angiology and Vascular Surgery, Santiago de Compostela University Hospital and A Coruña San Rafael Hospital (2012-15).

• Consultant Doctor in Medicine, Angiology and Vascular Surgery, Quirónsalud Marbella-Malaga Hospitals (2015-22).

• Head of the Angiology and Vascular Surgery Unit, Quirónsalud Marbella Hospital (2022- currently).

Member of Scientific Associations:

He is a member of the Board of Directors of the following:

American Cardiology JACC Journal and a revisor of the Board of Editors of JVET.

Secretary of the Andalusian Vascular Society and a member of the Committee of Directors of the Spanish Vascular Surgery Society (SEACV, in its Spanish abbreviation).

European Society of Vascular Surgery. A Professor of the ESVS Academy and Convenor for aorta and vascular access.

Vascular Surgery Quirónsalud Marbella Hospital has a team of specialists in Angiology and Vascular Surgery, supported by a nursing team with large experience and knowledge in the diagnosis and treatment of vascular diseases and their potential complications. This healthcare multidisciplinary approach helps us offer premium quality medical assistance to our patients.

The Angiology and Vascular Surgery Unit stands out for the implementation and development of technologically-advanced techniques in the comprehensive treatment of artery and venous diseases, with special interest in minimally- invasive endovascular treatments, not only to solve varicose vein issues, but also aneurysm and obstructive artery disease.

Our healthcare professionals deal with the prophylaxis, diagnosis and treatment of vascular diseases such as artery, venous and lymphatic disease. Each patient is taken through a process of individualised rapid and coordinated assessment.

Diseases, treatments, techniques and multidisciplinary units

Artery disease: endovascular or surgical treatment of aneurism or supra-aortic trunks occlusive disease; visceral, renal, aortic and limb arteries

• Venous disease: haemodynamic surgery and sclerotherapy of varicose veins
• Treatment of venous thromboembolism
• Lymphatic disease: diagnosis and treatment
• Artery-vein malformation: diagnosis and treatment
• Our hospital is a reference in the salvage of limbs (diabetic foot and critical limb ischaemia).

Pediatric orthopedist-traumatologist, specializes in surgical oncology

15 years of experience

• 
  
• He passed specialization in orthopedic surgery and traumatology at the Children's Research Hospital of St. Jude in Memphis, USA (2007-2008).
• Dr. Thorner Rubins currently teaches at the University of Barcelona.
• Нe is the head of the Department of Orthopedics and Traumatology at the Hospital Sant Joan de Déu in Barcelona.

Dr. Marta Morales Ballús is a pediatric ophthalmologist with over 20 years of experience in treating patients with congenital cataracts and performing pediatric anterior segment surgery. She holds a degree in general medicine and surgery from Barcelona University and is a member of the Catalan Society of Ophthalmology, the Spanish Strabology Society, and the European Paediatric Ophthalmological Society. She is also a teaching specialist at Hospital Sant Joan de Déu Barcelona.

Dr. Jose Hinojosa Mena-Bernal is a Spanish pediatric neurosurgeon. He specializes in neuro-oncology, neuroendoscopy, maxillofacial, and minimally invasive surgery. He leads the Neurosurgery Department at Sant Joan De Déu Children’s Hospital. Dr. Hinojosa has also held leadership positions at other major hospitals in Spain.

He has written 93 scientific papers. Dr. Hinojosa works as an editor and reviewer for leading neurosurgical journals. He is President of the Spanish Society of Pediatric Neurosurgery. He is also an active member of international groups such as ISPN and EANS. His roles show his strong reputation and influence in pediatric neurosurgery.

Dr. Aleix Prat is a clinical scientist with expertise in breast cancer research, gene expression, and clinical trials. He earned his MD from the University of Barcelona. He completed his oncology fellowship at Vall d’Hebron Institute of Oncology. Dr. Prat leads the Translational Genomics and Targeted Therapeutics in Solid Tumors Group at IDIBAPS. He is also President of SOLTI and serves on the Executive Committee of The Breast International Group.

Dr. Prat has published over 160 scientific papers. His work has received 13,479 citations, and he has an H-Index of 51. He is a Tenure-Track Professor at the University of Barcelona. He also directs the Breast Pathology–Senology Master’s degree. His roles highlight his strong academic and clinical contributions to oncology.

Dr. Jesus Soberino is an oncologist at Vall d’Hebron University Hospital and the Vall d’Hebron Institute of Oncology (VHIO). He specializes in breast cancer and melanoma. Dr. Soberino has led many phase 1–3 clinical trials. His work has helped approve important drugs, including CDK4/6 inhibitors for metastatic breast cancer and immunotherapies for melanoma.

His areas of expertise include endocrine therapy, managing hormone resistance, and developing new immunotherapies. Dr. Soberino is known for his patient-centered care. He actively collaborates in research to improve cancer treatment. He is accredited by VHIO and is a key member of the Breast Cancer and Melanoma Units.

Dr. Ana Oaknin is a Medical Oncologist with expertise in angiogenesis, DNA repair, and immunology. She focuses on gynecological cancers. Dr. Oaknin earned her medical degree and MD in Medical Oncology from Complutense University of Madrid. She also holds a PhD from Universidad Autonoma de Barcelona.

Dr. Oaknin is Co-Chair of the GEICO Group. She is a faculty member for the Gyn-Track in the European Society of Medical Oncology. She represents Spain in the GOG and GCIG committees. Dr. Oaknin is an active member of ASCO, ESMO, and SEOM. She has published over 100 scientific articles and presentations. She also leads several clinical trials in ovarian, cervical, and endometrial cancer.

Dr. Francesc Bosch is an expert in Chronic Lymphocytic Leukemia (CLL) and lymphomas. He leads research in the molecular causes and new treatments for CLL and other lymphoproliferative disorders.

He has published over 100 articles in leading journals, including The New England Journal of Medicine and Nature Medicine. Dr. Bosch oversees more than 80 clinical studies, from phase 1 to phase 3, and plays a key role in developing new drugs.

He is the Head of Hematology at Vall d’Hebron University Hospital and IOB Institute of Oncology. He also serves as president of GELLC and is a professor of hematology. His work has improved diagnosis and treatment for blood diseases.

Dr. Francesc Graus is a neurologist with expertise in paraneoplastic neurological syndromes, gliomas, and primary brain lymphomas. He established the first strict diagnostic criteria for paraneoplastic syndromes. He also identified important antibodies that are now used in diagnosis. His research showed the link between tumors and autoimmune neurological attacks.

Dr. Graus earned his MD and PhD from Universitat Autònoma de Barcelona. He completed his neurology residency in Barcelona and a neuro-oncology fellowship at Memorial Sloan-Kettering Cancer Center. He is an Emeritus investigator at IDIBAPS. He founded and served as president of the European Association of Neuro-Oncology. He is also the former chief of neurology at Hospital Clinic Barcelona.

Dr. Fernando Azpiroz Vidaur is a highly experienced gastroenterologist with over 35 years of experience in gastrointestinal research, gut disorders, gut motility, visceral sensitivity, and intestinal gas dynamics. He has received medical degrees from the University of Valladolid and San Carlos University Hospital in Madrid, a fellowship from Mayo Clinic's Gastrointestinal Research Unit, and numerous awards for his clinical research. He is also the President of the European Society of Neurogastroenterology and Motility and a Councilor of the International Motility Group.

One of the world-renowned pioneers in gastrointestinal surgery. Has developed new techniques for the colon and rectum cancer treatment TaTMEТ and NOTES — applied now around the world.
Has performed over 15,000 surgeries.
Performs over 1,000 interventions a year using minimally invasive techniques.
President of the Association of Surgeons-Endoscopists in Europe.

CURRICULUM VITAE

VOLKERT B. WREESMANN MD PhD

Consultant Otolaryngologist

Oncologic Head and Neck Surgeon

Thyroid and Parathyroid Surgeon

Facial Plastic Surgeon

Principal Positions

• Centro Medico Teknon, Barcelona, Spain

Lead Consultant, ANDSURGEONS ENT, Head & Neck and Facial Plastic Surgery Program (clinical service delivered in collaboration with Teknon).

July 1st 2024 – present

• Juaneda, Ciutadella Menorca, Spain

Visiting Consultant Otolaryngologist-Head and Neck Surgeon

January 2025 – present

• Avantmedic, Lleida, Spain

Visiting Consultant Otolaryngologist-Head and Neck Surgeon

September 1st 2024 – November 1st 2025

• Clinica Omega Zeta, Andorra

Consultant Otolaryngologist-Head and Neck Surgeon

March 1st 2022 – present

• University Hospitals Dorset NHS Foundation Trust

Consultant Otolaryngologist-Head and Neck Surgeon

August 1st 2021 – October 1st 2023

• Oxford University Hospitals NHS Foundation Trust

Honorary Consultant Otolaryngologist-Head and Neck Surgeon

May 1st 2021 – April 30th 2024

• Portsmouth Hospitals University NHS Trust, Portsmouth, UK

Consultant Otolaryngologist-Head and Neck Surgeon

July 18th 2016 – April 30th 2021

• Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK

Consultant Otolaryngologist-Head and Neck Surgeon

November 7th 2015 – May 31st 2016

• Heart of England NHS Trust, Birmingham, UK

Consultant Otolaryngologist-Head and Neck Surgeon

March 1st 2015 – October 31st 2015

• University Medical Center Utrecht, Netherlands

Consultant Otolaryngologist-Head and Neck Surgeon

November 1st 2013 – June 1st 2014

Memberships

• American Head and Neck Society – Member

Netherlands Academy of Otolaryngology - Member

Professional Licences

• United Kingdom

GMC Certification

Fully Registered Medical Practitioner with Specialist Registration with a License to Practice

Registered: 02/02/2015

GMC # 7499626

• United States of America

New York State Department of Health

New York State Education Department

Registered: July 2011

License# P80949

Physician

• Netherlands

Dutch Ministry of Health (BIG Registration)

BIG Registered: 22-06-2005

BIG #19063373601

Physician

Dutch Specialist Board (RGS)

RGS registered: 01-02-2011

RGS #1911979

Otolaryngology-Head and Neck Surgeon

• Spain

Collegi de Metges de Barcelona

COMB: 63638

• Andorra

Collegi de Metges d’Andorra

RPS: 03098

COMA: 876

Education

• Memorial Sloan-Kettering Cancer Center

Surgical Fellowship, Head and Neck Surgery

New York, New York, USA

August 1st 2011 - July 31st 2013

600 bed dedicated cancer center

Performed 1200 major oncologic head and neck resections in 2 years

• United States of America ECFMG Certification

United States Medical Licensing Examination (USMLE)

Certification: June 22nd, 2010

Scores: 

   Step I: 244/99 

   Step IIa-Clinical knowledge: 227/94

   Step IIb-Clinical Skills: PASSED

   Step III: 206/85

• Netherlands Cancer Institute

Surgical Fellowship, Head and Neck Surgery

Amsterdam, The Netherlands

February 1st 2011 - July 31st 2011

Specialized Head and Neck Cancer Surgery Department

200 bed hospital

• Amsterdam University Medical Center/Netherlands Cancer Institute

Residency Training, Otolaryngology-Head and Neck Surgery

Amsterdam, the Netherlands

February 1st 2006 – January 31st 2011

• University of Amsterdam School of Medicine

Medical Doctor (MD)

Amsterdam, the Netherlands

December 2002 - January 28th 2005

• University of Amsterdam

Doctor of Philosophy (PhD), Molecular Biology

Amsterdam, the Netherlands

Thesis title: Molecular-cytogenetic characterization of head and neck cancer

December 2nd, 2004

• Erasmus University School of Medicine

Doctoral Degree in Medicine

Rotterdam, the Netherlands

September 1994 - November 17th, 1998

Research Training

• Memorial Sloan-Kettering Cancer Center

Laboratory of Epithelial Cancer Biology, Head and Neck Service, Department of Surgery, New York, New York, USA

Research Fellowship in Molecular Oncology

Supervisors: Dr. Bhuvanesh Singh MD, PhD and Dr. Jatin P. Shah, MD, FACS

March 1st 1999 - September 30st 2002

• University of California San Francisco (UCSF)

Department of Otolaryngology-Head and Neck Surgery, San Francisco, California, USA

Post-doctoral Research Fellowship in Head and Neck Oncology

Supervisors: Dr. Steven Wang MD And Prof David Eisele MD

February 2005 - January 2006

Academic Activities

University of Amsterdam

Doctorate Examination Committee member

• September 17th, 2013 - PhD Candidate: Dr. I.J. Nixon (United Kingdom)
• October 17th 2014 - PhD Candidate: Dr. J. Pramana (Netherlands)
• November 17th 2015 - PhD candidate: Dr. H. van Monsjou (Netherlands)
• December 11th 2018 - PhD Candidate: Dr. Tihana Ibrahimpasic (United States)
• January 18th, 2021 - PhD Candidate: Dr. Laura Wang (Australia)
• June 2nd, 2021 - PhD Candidate: Dr. Caroline Verhagen (Netherlands)

Conference Faculty

• Advanced Laryngopharyngeal Cancer: Functional Preservation and Rehabilitation, Portsmouth, June 25th - 26th, 2020 (postponed due to COVID) - Chairman
• Functional Preservation and Rehabilitation after Treatment for Advanced Laryngeal Cancer, Portsmouth, March 14th - 15th, 2019 - Chairman
• Portsmouth Parathyroid Conference, Portsmouth, December 14th 2018 – Chairman

Editorial Roles

• European Journal of Surgical Oncology

Associate Editor

January 1st 2023 – present

• European Journal of Surgical Oncology

Guest Editor

March issue 2018, Volume 44, Issue 3, p275-378 - Special issue on thyroid cancer management

• Journal of Oral Pathology and Medicine

Guest Editor

November issue 2021, Volume 51, Issue 10 - Special issue on vascular malformations and tumors of the head and neck

• Scientific Journal Reviewer

Oral Oncology, European Journal of Surgical Oncology, Journal of Surgical Oncology, Head and Neck, International Journal of Cancer

• Scientific Project and Grant Reviewer

Netherlands: Dutch Cancer Society

France: Institute National du Cancer

Awards

• New York Head and Neck Society

Annual Meeting, New York, NY, March 2002

Title of study presented: “MUC1 is a target if 1q amplification and pertains a grave clinical prognosis in papillary thyroid cancer”

Invited Lectures

• European Society of Surgical Oncology meeting, Krakow, 2016
• Barcelona Society of Neurosurgery, Annual Meeting, Baqueira, Spain, February, 2017
• University of Edinburgh, Department of Otolaryngology Academic Conference, March 17th 2017
• Medilex: Performance of Medical Specialists, Zeist, Netherlands, November 9th 2017
• Medilex: Performance of Medical Specialists, Driebergen, Netherlands, October 11th 2017
• Wessex Head and Neck and Thyroid Network Education Day, May 3rd, 2017
• Portsmouth Parathyroid Conference, Portsmouth, UK, December 14th 2018
• Global Post-laryngectomy Rehabilitation Academy, Portsmouth, UK, March 14th 2019
• Health Care Quality Conference, Beverwijk, Netherlands, March 25th, 2019

Published Research Reports

• The growing precision of diagnostic pathways in thyroid nodule evaluation. 

Bekker J, Wreesmann VB. 

Eur J Surg Oncol. 2025 Jan;51(1):109374.

• Special issue: Management of vascular tumors and malformations of the head and neck. 

Oomen KPQ, Brennan PA, Wreesmann VB. 

J Oral Pathol Med. 2022 Nov;51(10):829.

• Angiosarcomas of the head and neck: Impact of large data analysis on clinical management.
•  
• Wreesmann VB, Oomen KP, Brennan PA.

J Oral Pathol Med. 2022 Nov;51(10):904-910.

• Current classification of vascular anomalies of the head and neck. 

Oomen KPQ, Wreesmann VB. 

J Oral Pathol Med. 2022 Nov;51(10):830-836.

• A novel classification of carotid body tumors.

Wreesmann VB, Nixon IJ. 

Eur. J. Surg. Oncol. May, 2021

• Management of the contralateral central neck in differentiated thyroid cancer: A contentious issue. 

Shaha AR, Tuttle RM, Wreesmann VB. 

Eur. J. Surg. Oncol. 2021 Apr;47(4):717-719.

• Improvement of oral cancer screening quality and reach: The promise of artificial intelligence.
•  
• Kar A, Wreesmann VB, Shwetha V, Thakur S, Rao VUS, Arakeri G, Brennan PA.

J Oral Pathol Med. 2020 Mar 11

• The risk-benefit ratio of chemoradiation treatment in head and neck squamous cell carcinoma: value of extranodal spread and margin status. 

Ammar M, Wreesmann VB. 

Journal of ENT Masterclass, Yearbook 2018, Volume 11, Nr. 1, December 1st, 2018

• Nasal obstruction secondary to an inverted midline supernumerary tooth. 

Jones L, Hilton JM, Heyman J, Viswanathan H, Wreesmann VB, Hayes SM. 

Ann R Coll Surg Engl. 2019 Jan;101(1)

• Fanconi anemia and homologous recombination gene variants are associated with functional DNA repair defects in vitro and poor outcome in patients with advanced head and neck squamous cell carcinoma. 

Verhagen CVM, Vossen DM, Borgmann K, Hageman F, Grénman R, Verwijs-Janssen M, Mout L, Kluin RJC, Nieuwland M, Severson TM, Velds A, Kerkhoven R, O'Connor MJ, van der Heijden M, van Velthuysen ML, Verheij M, Wreesmann VB, Wessels LFA, van den Brekel MWM, Vens C. 

Oncotarget. 2018 Apr 6;9(26):18198-18213.

• Complete nasal obstruction secondary to pacemaker insertion. 

Jones TL, Wreesmann VB, Nilssen E, Hilton J, Hayes SM. 

Ann R Coll Surg Engl. 2018 May;100(5)

• Optimization of the risk-benefit ratio of differentiated thyroid cancer treatment. 

Nasef HO, Nixon IJ, Wreesmann VB. Eur J Surg Oncol. 

2018 Mar;44(3):276-285. Review.

• The risk/benefit ratio of differentiated thyroid cancer treatment: Exploring treatment de-escalation. 

Wreesmann VB; on behalf of EJSO. 

Eur J Surg Oncol. 2018 Mar;44(3):275.

• Aggressive differentiated thyroid cancer. 

Janjua N, Wreesmann VB. 

Eur J Surg Oncol. 2018 Mar;44(3):367-377. Review.

• Role of extracapsular nodal spread and surgical margin status in defining high-risk head and neck squamous cell carcinoma and its treatment intensity. 

Wreesmann VB. 

International Journal of Head and Neck Surgery, April-June 2017; 8(2): 76-83.

• An International Multi-Institutional Validation of Age 55 Years as a Cutoff for Risk Stratification in the AJCC/UICC Staging System for Well-Differentiated Thyroid Cancer.              

Nixon IJ, Wang LY, Migliacci JC, Eskander A, Campbell MJ, Aniss A, Morris L, Vaisman F, Corbo R, Momesso D, Vaisman M, Carvalho A, Learoyd D, Leslie WD, Nason RW, Kuk D, Wreesmann V, Morris L, Palmer FL, Ganly I, Patel SG, Singh B, Tuttle RM, Shaha AR, Gönen M, Pathak KA, Shen WT, Sywak M, Kowalski L, Freeman J, Perrier N, Shah JP. 

Thyroid. 2016 Mar;26(3):373-80.

• Influence of extracapsular nodal spread extent on prognosis of oral squamous cell carcinoma. 
•  
• Wreesmann VB, Katabi N, Palmer FL, Montero PH, Migliacci JC, Gönen M, Carlson D, Ganly I, Shah JP, Ghossein R, Patel SG.

Head Neck. 2016 Apr;38 Suppl 1:E1192-9.

• Defining a Valid Age Cutoff in Staging of Well-Differentiated Thyroid Cancer. 

Nixon IJ, Kuk D, Wreesmann V, Morris L, Palmer FL, Ganly I, Patel SG, Singh B, Tuttle RM, Shaha AR, Gönen M, Shah JP. 

Ann Surg Oncol. 2015 Jul 28.

• Prognostic value of vascular invasion in well-differentiated papillary thyroid carcinoma.
•  
• Wreesmann VB, Nixon IJ, Rivera M, Katabi N, Palmer F, Ganly I, Shaha AR, Tuttle RM, Shah JP, Patel SG, Ghossein RA.

Thyroid. 2015 May;25(5):503-8.

• Head and neck squamous cell carcinoma in young patients.

van Monsjou HS, Wreesmann VB, van den Brekel MW, Balm AJ. 

Oral Oncol. 2013 Dec;49(12):1097-102.

• Oral and oropharyngeal squamous cell carcinomas in young patients: The Netherlands Cancer Institute experience. 

van Monsjou HS, M Lopez-Yurda, M. Hauptmann, Balm AJ, van den Brekel MM, Wreesmann VB. 

Head Neck. 2013 Jan;35(1):94-102.

• Oropharyngeal squamous cell carcinoma: a unique disease on the rise?

van Monsjou HS, Balm AJ, van den Brekel MM, Wreesmann VB. 

Oral Oncol. 2010 Nov;46(11):780-5.

• Closure of tracheoesophageal fistula with prefabricated revascularized bilaminar radial forearm free flap.

Wreesmann VB, Smeele LE, Hilgers FJ, Lohuis PJ. 

Head Neck. 2009 Jun;31(6):838-42.

• Clinical impact of molecular analysis on thyroid cancer management.

Wreesmann VB, Singh B. 

Surg Oncol Clin N Am. 2008 Jan;17(1):1-35.

Genetic abnormalities associated with chemoradiation resistance of head and neck squamous cell carcinoma. 

van den Broek GB, Wreesmann VB, van den Brekel MW, Rasch CR, Balm AJ, Rao PH. 

Clin Cancer Res. 2007 Aug 1;13(15 Pt 1):4386-91.

• Association of CD44 V3-containing isoforms with tumor cell growth, migration, matrix metalloproteinase expression, and lymph node metastasis in head and neck cancer.

Wang SJ, Wreesmann VB, Bourguignon LY. 

Head Neck. 2007 Jun;29(6):550-8.

• Downregulation of Fanconi anemia genes in sporadic head and neck squamous cell carcinoma.
•  
• Wreesmann VB, Estilo C, Eisele DW, Singh B, Wang SJ.

ORL J Otorhinolaryngol Relat Spec. 2007;69(4):218-25. Epub 2007 Apr 4.

• Patterns of expression of cell cycle/apoptosis genes along the spectrum of thyroid carcinoma progression.
•  
• Saltman B, Singh B, Hedvat CV, Wreesmann VB, Ghossein R.
•  
• Surgery. 2006 Dec;140(6):899-905; discussion 905-6.

• Repetitive endoscopic sinus surgery failure: a role for radical surgery?

Videler WJ, Wreesmann VB, van der Meulen FW, Knegt PP, Fokkens WJ. 

Otolaryngol Head Neck Surg. 2006 Apr;134(4):586-91.

• MUC1 plays a role in tumor maintenance in aggressive thyroid carcinomas.
•  
• Patel KN, Maghami E, Wreesmann VB, Shaha AR, Shah JP, Ghossein R, Singh B.
•  
• Surgery. 2005 Dec;138(6):994-1001; discussion 1001-2.

• Chromosomal aberrations in squamous cell carcinomas of the upper aerodigestive tract: biologic insights and clinical opportunities.

Wreesmann VB, Singh B. 

J Oral Pathol Med. 2005 Sep;34(8):449-59. Review.

• Molecular profiling of tumor progression in head and neck cancer.
•  
• Belbin TJ, Singh B, Smith RV, Socci ND, Wreesmann VB, Sanchez-Carbayo M, Masterson J, Patel S, Cordon-Cardo C, Prystowsky MB, Childs G.
•  
• Arch Otolaryngol Head Neck Surg. 2005 Jan;131(1):10-8.

• Identification of novel prognosticators of outcome in squamous cell carcinoma of the head and neck.

Wreesmann VB, Shi W, Thaler HT, Poluri A, Kraus DH, Pfister D, Shaha AR, Shah JP, Rao PH, Singh B. 

J Clin Oncol. 2004 Oct 1;22(19):3965-72.

• Follicular variant of papillary thyroid carcinoma: genome-wide appraisal of a controversial entity.

Wreesmann VB, Ghossein RA, Hezel M, Banerjee D, Shaha AR, Tuttle RM, Shah JP, Rao PH, Singh B. 

Genes Chromosomes Cancer. 2004 Aug;40(4):355-64.

• Genome-wide profiling of papillary thyroid cancer identifies MUC1 as an independent prognostic marker.

Wreesmann VB, Sieczka EM, Socci ND, Hezel M, Belbin TJ, Childs G, Patel SG, Patel KN, Tallini G, Prystowsky M, Shaha AR, Kraus D, Shah JP, Rao PH, Ghossein R, Singh B. 

Cancer Res. 2004 Jun 1;64(11):3780-9.

• Genetic abnormalities associated with nodal metastasis in head and neck cancer.

Wreesmann VB, Wang D, Goberdhan A, Prasad M, Ngai I, Schnaser EA, Sacks PG, Singh B. 

Head Neck. 2004 Jan;26(1):10-5.

• Human papillomavirus DNA and p53 polymorphisms in squamous cell carcinomas from Fanconi anemia patients.
•  
• Kutler DI, Wreesmann VB, Goberdhan A, Ben-Porat L, Satagopan J, Ngai I, Huvos AG, Giampietro P, Levran O, Pujara K, Diotti R, Carlson D, Huryn LA, Auerbach AD, Singh B.
•  
• J Natl Cancer Inst. 2003 Nov 19;95(22):1718-21.

• Chromosomal aberrations in patients with head and neck squamous cell carcinoma do not vary based on severity of tobacco/alcohol exposure.

Singh B, Wreesmann VB, Pfister D, Poluri A, Shaha AR, Kraus D, Shah JP, Rao PH. 

BMC Genet. 2002 Nov 14;3:22. Epub 2002 Nov 14.

• Genome-wide appraisal of thyroid cancer progression.
•  
• Wreesmann VB, Ghossein RA, Patel SG, Harris CP, Schnaser EA, Shaha AR, Tuttle RM, Shah JP, Rao PH, Singh B.
•  
• Am J Pathol. 2002 Nov;161(5):1549-56.

• Refractory chronic sinusitis: evaluation of symptom improvement after Denker’s procedure.
•  
• Wreesmann VB, Fokkens WJ, Knegt PP.
•  
• Otolaryngol Head Neck Surg. 2001 Nov;125(5):495-500.

• Inflammatory pseudotumour (inflammatory myofibroblastic tumour) of the pancreas: a report of six cases associated with obliterative phlebitis.
•  
• Wreesmann V, van Eijck CH, Naus DC, van Velthuysen ML, Jeekel J, Mooi WJ.
•  
• Histopathology. 2001 Feb;38(2):105-10.

• Screening for genetic aberrations in papillary thyroid cancer by using comparative genomic hybridization.
•  
• Singh B, Lim D, Cigudosa JC, Ghossein R, Shaha AR, Poluri A, Wreesmann VB, Tuttle M, Shah JP, Rao PH.
•  
• Surgery. 2000 Dec;128(6):888-93;discussion 893-4.

Abstracts (Presentations at scientific meetings):

• Genome-wide screening for genetic prognostic factors in papillary thyroid carcinoma.
•  
• Wreesmann VB, Ghossein RA, Poluri A, Shaha AR, Tuttle RM, Shah JP Rao PH, Singh B.

Fifth International Conference on Head and Neck Cancer San Francisco, CA, July 2000.

• Hierarchical Clustering (HC): a Novel Approach to Evaluating the Prognostic Value of Laboratory Parameters in Patients (Pts) Undergoing Chemoradiation Treatment (CRT) for Advanced Laryngopharyngeal Carcinoma (LPC). 

Singh B, Pfister D, Wreesmann VB, Li R, Gogineni S, Bosl G, Hoffman RH, Shah JP, Rao PH. 

37th Annual Meeting of the American Society of Clinical Oncology; New Orleans LA, May 2001.

• Gain of 1q is unique to the tall cell variant of papillary thyroid cancer.

Wreesmann VB, Ghossein RA, Tuttle RM, Shaha AR, Robbins R, Shah JP, Rao PH, Singh B. 

73rd annual meeting of the American Thyroid Association, Washington D.C. November 2001.

• MUC1 is a target of 1q amplification and pertains a grave clinical prognosis in papillary thyroid cancer. 

Wreesmann VB, Sieczka E, Socci ND, Hezel M, Belbin TJ, Childs G, Patel SG, Shah JP, Rao PH, Ghossein RG, Singh B. 

Annual Meeting of the New York Head and Neck Society, New York, NY, March 2002.

• Genome wide screening identified gains and losses as independent prognostic variables in patients with head and neck squamous cell carcinoma (HNSCC). 

Singh B, Wreesmann VB, Thaler HT, Shi W, Shah JP, Shaha AR, Kraus DH, Boyle JO, Pfister D, Rao PH. 

38th Annual Meeting of the American Society of Clinical Oncology; Orlando, Fl May 2002.

• p53 inactivation by human papillomavirus (HPV) in Fanconi anemia associated squamous cell carcinoma. 

Kutler DI, Goberdhan A, Wreesmann VB, Giampietro PF, Auerbach AD, Singh B. 

The Sixth Research Workshop on the Biology, Prevention, and Treatment of Head and Neck Cancer; Washington D.C.; October 2002.

• Identification of novel prognostic factors in head and neck squamous cell carcinoma. 
•  
• Wreesmann VB, Shi W, Thaler HT, Shah JP, Shaha AR, Kraus DH, Boyle JO, Pfister D, Rao PH, Singh B. 

7th symposion on Research in Head and Neck Cancer; Dusseldorf, Germany, September 4-6 2003.

• Molecular profiling of aggressive papillary thyroid cancer: prognostic significance of MUC1 alterations. 

Wreesmann VB, Sieczka E, Socci ND, Hezel M, Belbin TJ, Childs G, Patel SG, Patel KN, Tallini G, Prystowsky M, Shaha AR, Kraus D, Shah JP, Rao PH, Ghossein RA, Singh B. 

7th symposion on Research in Head and Neck Cancer; Dusseldorf, Germany, September 4-6 2003.

• Chromosomal aberrations in Fanconi anemia-associated squamous cell carcinomas differ from sporadic squamous cell carcinomas from the general population. 

Kutler DI, Rao PH, Wreesmann VB, Goberdhan A, Ngai I, Huvos AG, Giampietro PF, Levran O, Pujara K, Diotti R, Auerbach AD, Singh B. 

15th annual Fanconi Anemia Research Fund scientific symposium, Houston TX, Oct 2003.

• Molecular classification of Fanconi anemia(FA)-associated head and neck squamous cell carcinoma (HNSCC) using oligonucleotide microarrays. 

Kutler DI, Ganly I, Wreesmann VB, Goberdhan A, Ngai I, Huvos AG, Giampietro PF, Levran O, Pujara K, Diotti R, Auerbach AD, Singh B. 

15th annual Fanconi Anemia Research Fund scientific symposium, Houston TX, Oct 2003.

•  
• Genotyping follicular cell-derived thyroid neoplasia: a CGH study of 150 cases.

Wreesmann VB, Ghossein RA, Socci N, Shaha AR, Tuttle RM, Shah JP, Rao PH, Singh B. 

Sixth International Conference on Head and Neck Cancer, Washington DC, August 2004.

• Downregulation of Fanconi anemia genes in sporadic squamous cell carcinomas of the head and neck. 

Wreesmann VB, Estilo C, Eisele DW, Singh B, Wang SJ. 

208th meeting of the Netherlands Society of Otolaryngology-Head and Neck Surgery, Utrecht, April 7th 2006.

• Extracapsular nodal spread does not predict outcome in clinically node negative oral cavity squamous cell carcinoma. 

Wreesmann VB, Ghossein RA, Carlson D, Ganly I, Palmer F, Montero P, Shah JP, Patel SG. 

AHNS 2013 Annual Meeting, April 10 & 11, 2013, Orlando Florida.

• Minor (<2mm) extracapsular spread is not an adverse predictor of outcome in metastatic squamous cell carcinoma of the oral cavity. 

Wreesmann VB, Ghossein RA, Carlson D, Ganly I, Palmer F, Montero P, Shah JP, Patel SG. 

Presented at the AHNS 2014 Annual Meeting, July 2014, New York, New York.

Books, Chapters:

• Molecular Biology as applied to Head and Neck Oncology

Wreesmann VB, Singh B.

Stell and Maran's Textbook of Head and Neck Surgery and Oncology

Fifth Edition

Chapter, edited by John Watkinson and Ralph Gilbert

• Molecular-Cytogenetic Characterization of Head and Neck Cancer: Identification of molecular prognostic factors and targets of therapy

Wreesmann VB, Singh B.

Book, Amsterdam 2004

Reviewed in: Head and Neck: Volume 29, Issue 1, pages 82–83, January 2007

• Open Conservation Surgery for Laryngeal Cancer

Wreesmann VB, Ganly I

Scott-Brown's Otorhinolaryngology and Head and Neck Surgery, Eighth Edition

Chapter 27

CRC Press, Taylor-Francis Group, June 12th, 2018

• Molecular Oncology

Wreesmann V.B.

Self-Assessment in Head and Neck Surgery and Oncology, First Edition

Chapter 21

Elsevier 2014

Research grants:

Netherlands Cancer Institute “Startgeld” Grant 2008

Project: Fanconi anemia in head and neck cancer

Principal investigators: Wreesmann VB, van den Brekel MW, Balm AJM, Vens C.

Amount granted: 300.000 euro