Bone Marrow Transplant for Pediatric Osteosarcoma at Sheba Hospital- JCI accreditated and Top-10 Hospitals 2025 by Newsweek
What's included in this package
Medical Procedures
- Consultation with an oncologist
- Complex diagnosis of sarcoma
- Bone marrow transplantation
- 3 meals per day by nutritionist
- 24-hr nurse services
- Electrocardiogram (ECG)
- Blood tests
- Chest X-ray
- Anti-HIV test
- Anti-HBC test
- Anti-HCVAb test
- Echocardiography
- Complete blood count (CBC)
- Biochemistry blood test
- PET/CT
- Consultation with an oncologist
- Consultation with an immunologist
- Consultation with a cardiologist
- Consultation with a pediatric hematologist
- Consultation with a pediatrician
- Сonsultation with an oncohematologist
- Head MRI
- Biopsy
- Computerized Bone Mineralometry (CBM)
- Complete blood count with cancer markers and a proteinogram
Duration
- 30 days in the hospital
Accommodation
Hospitalization
Transport
Transfer airport-clinic-airport
Additional information
Bone Marrow Transplant for Pediatric Osteosarcoma
Sheba Medical Center – Advanced, Personalized Transplant Care for Children
At Sheba Medical Center, we understand how difficult it is for families to face a diagnosis of osteosarcoma. As the most common primary bone cancer in children and adolescents, it requires highly specialized, coordinated care and strong support for both the child and their loved ones.
While most children are successfully treated with a combination of chemotherapy and surgery, bone marrow transplantation (BMT) may be considered in selected, more complex cases, offering an advanced treatment approach when additional therapeutic intensity is needed.
Our pediatric transplant program combines leading medical expertise, innovative therapies, and compassionate, family-centered care to support children at every stage of treatment.
When is a Bone Marrow Transplant Needed?
Bone marrow transplantation is not routinely used for all children with osteosarcoma, but may be recommended in specific situations, including:
High-risk disease, particularly when cancer has spread (metastatic osteosarcoma)
Relapsed disease, when osteosarcoma returns after initial treatment
Cases where a more intensive treatment strategy is appropriate
In these settings, BMT allows doctors to deliver high-dose chemotherapy to target cancer cells, followed by the infusion of healthy stem cells to restore bone marrow and support recovery.
Types of Transplant
Autologous Transplant (Child’s Own Cells)
This is the most commonly used transplant approach when BMT is part of osteosarcoma treatment.
Stem cells are collected from the child before intensive therapy
High-dose chemotherapy is administered
The child’s own stem cells are reinfused to rebuild healthy bone marrow
This approach enables delivery of higher-dose treatment while supporting safe recovery.
Allogeneic Transplant (Donor Cells)
In carefully selected cases, Sheba Medical Center also offers allogeneic (donor) transplantation as part of a comprehensive care strategy.
This option may be considered when:
An alternative stem cell source is needed
An immune-based treatment approach may provide additional benefit
Donor options at Sheba include:
Matched sibling donors
Matched unrelated donors from international registries
Haploidentical (half-matched) family donors
A potential advantage of donor transplantation is the graft-versus-tumor effect, where the new immune system may help identify and target remaining cancer cells.
Precision Matching and Advanced Technology
Sheba Medical Center utilizes an advanced on-site HLA laboratory for high-resolution genetic testing, ensuring the most accurate donor matching when needed.
This precision enhances safety and supports optimal transplant outcomes.
Advanced Pediatric Osteosarcoma Care
Care at Sheba is highly coordinated and tailored to each child:
Integration of chemotherapy, surgery, and transplant strategies
Access to innovative and emerging therapies
Close collaboration between pediatric oncologists, orthopedic surgeons, and transplant specialists
Comprehensive supportive care throughout treatment
Specialized Pediatric Transplant Environment
Children receiving BMT are treated in dedicated pediatric transplant units designed for safety and comfort:
Child-friendly, highly protected environments
Advanced infection prevention systems
Continuous care by experienced pediatric specialists
Every aspect of care is adapted to support children physically and emotionally.
Clinical Expertise
Sheba Medical Center is a leading center for pediatric oncology and transplantation, offering:
Experience in treating complex and high-risk osteosarcoma cases
Expertise in high-dose therapy with stem cell support
Outcomes aligned with leading international centers
Long-term follow-up focused on growth, recovery, and quality of life
Care That Supports the Whole Family
We understand that this journey affects the entire family.
At Sheba, children and their families are supported by a multidisciplinary team including physicians, nurses, psychologists, and care coordinators—ensuring guidance, reassurance, and continuous support throughout treatment.
Why Families Choose Sheba for Pediatric BMT
Leading pediatric transplant center
Expertise in complex bone tumors
Access to a wide range of donor options
Advanced technologies and treatment approaches
Compassionate, child-centered care
Dedicated international patient services
A Message of Hope
At Sheba Medical Center, we combine advanced science with compassionate care to give every child the best possible chance for recovery. Even in complex cases like osteosarcoma, we are committed to supporting families with strength, clarity, and hope every step of the way.
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- Personal medical coordinator
- Medical travel arrangements — booking of air tickets and hotel rooms at special partner prices
- Patient advocacy during medical travel
Program price
What's NOT included in this package
Doctor
Dr. Hana Golan, MD, heads the Pediatric Hemato-Oncology and Bone Marrow Transplantation (BMT) Division at Sheba Medical Center. She specializes in childhood cancers, with a focus on neuroblastoma and other high-risk solid tumors.
She leads one of the region’s most advanced pediatric oncology programs. She manages complex, high-risk cases and practices at a hospital ranked in the global top 10.
She is the principal investigator of the High-Risk Neuroblastoma ESIOP protocol. She serves as an investigator in international Phase I/II trials and as the national coordinator of multicenter oncology protocols. She led the development of computerized chemotherapy protocols and patient databases to improve safety.
She earned her MD from the Technion. She completed residencies in pediatrics and pediatric hemato-oncology at Sheba. She conducted advanced research in transplantation immunology at the Weizmann Institute. She is board-certified in Pediatrics and Pediatric Hematology-Oncology. She is a Senior Lecturer at the Sackler Faculty of Medicine, Tel Aviv University. Her research focuses on cancer stem cells, targeted therapies, treatment-resistant malignancies, and cannabinoid-related oncology.
How are we doing?
About the clinic
Sheba Medical Center is the largest hospital in the Middle East and one of the world’s leading medical institutions, consistently ranked among the global Top 10. Recognized by Newsweek and Statista for eight consecutive years, it ranked 7th worldwide in 2026. The hospital delivers comprehensive multidisciplinary care across all major specialties, including oncology, hematology, cardiology, neurology, and advanced surgery, treating over 2 million patients annually, including international cases. With more than 200 physicians listed among Forbes' Top Doctors, Sheba is a global leader in CAR-T and TIL immunotherapies, precision medicine, and minimally invasive surgery, making it a trusted destination for complex and advanced treatment.
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