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Metastatic Gastric (Stomach) Cancer Evaluation & Personalized Systemic Treatment Strategy at Sheba Hospital- JCI accredited and Top-10 Hospitals 2026 by Newsweek

Israel Ramat Gan
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Sheba Medical Center
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Facilities 5.0
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Highly recommended
98% Clients recommended this clinic
42 patients
chose this clinic for their care in the last year

What's included in this package

Medical Procedures
  • PET/CT
  • Consultation with an oncologist
  • Histopathology revision
  • Immunotherapy
  • Chemotherapy
  • Blood tests
Duration
  • 12 days in the hotel
Accommodation

Accommodation is not included

Transport
  • Transfer is not included

Additional information

Advanced Metastatic Stomach Cancer Evaluation & Personalized Systemic Treatment Strategy
Overview
This program is designed for patients diagnosed with metastatic gastric signet-ring cell carcinoma, requiring comprehensive evaluation and development of an individualized systemic treatment strategy.
Treatment is provided at Sheba Medical Center — a Top-10 globally ranked hospital, with extensive experience in advanced gastrointestinal oncology.
Clinical Situation
Metastatic gastric cancer, particularly signet-ring cell subtype, is a biologically aggressive disease that requires:
precise staging
molecular profiling
multidisciplinary decision-making
In most cases, treatment is systemic (chemotherapy / targeted therapy / immunotherapy) rather than surgical.
Program Structure
Comprehensive On-Site Assessment (5–7 days)
The program begins with a detailed diagnostic phase to confirm disease extent and define treatment options:
Advanced imaging review (CT / PET-CT)
Laboratory panel including tumor markers (CEA, CA 19-9, CA 125)
Full biochemical and hematologic profile
Pathology review
Multidisciplinary consultations:
GI oncologist
radiologist
cardiologist
neurologist (if indicated)
additional specialists as required
Molecular & Genetic Profiling (if indicated)
To guide targeted therapy, additional testing may include:
BRAF, KRAS, NRAS mutations
MMR / MSI status
FISH testing
This step is critical for identifying patients who may benefit from personalized or targeted treatments
Personalized Oncology Treatment Strategy
Following evaluation, a customized treatment plan is developed, which may include:
systemic chemotherapy
targeted therapy
immunotherapy
supportive and symptom-oriented care
Key Advantages

Expertise in advanced and metastatic gastric cancer
Personalized treatment plan after on-site evaluation
Access to molecular diagnostics and targeted therapies
Multidisciplinary tumor board decision-making
Strategy focused on optimizing outcomes and avoiding ineffective treatments
Estimated Timeline
Diagnostic phase: 5–7 working days
Treatment initiation: immediately after plan confirmation
Estimated Costs
Comprehensive assessment: ~$2,400 – $4,200
Additional molecular testing: ~$500 – $4,000
Systemic therapy (per cycle): ~$1,800 – $4,000
Final cost is determined after in-person evaluation.
Important Note
The exact treatment strategy, including:
type of systemic therapy
need for additional testing
treatment sequence
is defined only after full diagnostic evaluation and multidisciplinary review

24/7 Bookimed assistance
  • Personal medical coordinator
  • Medical travel arrangements — booking of air tickets and hotel rooms at special partner prices
  • Patient advocacy during medical travel

Program price

$8,000

What's NOT included in this package

Airfare
Hotel
Additional activities not included

Doctor

Einat Shacham Shmueli
Gastroenterologist
26 years of experience
Board certified professional

Dr. Einat Shacham Shmueli is a senior medical oncologist at Sheba Medical Center. She specializes in gastrointestinal cancers, treating the colon, stomach, and pancreas. Dr. Shacham Shmueli holds dual board certifications in oncology and gastroenterology. She trained at UCSF in the United States. Her clinic at Sheba Medical Center is ranked among the top 10 hospitals worldwide.

  • Authored over 25 peer-reviewed publications on tumor biology and new treatments.
  • Serves as an investigator for the National Cancer Institute (NCI) programs.
  • Manages metastatic disease using precision diagnostics and specialized biomarkers.
  • Member of the Israel Society of Oncology and Radiotherapy.
Read more
View doctor profile

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About the clinic

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Sheba Medical Center

Sheba Medical Center is the largest hospital in the Middle East and ranked 7th worldwide by Newsweek in 2026. It treats over 2 million patients annually and is a global leader in CAR-T and TIL immunotherapies. Core specialties include oncology, immunotherapy, precision medicine, and cardiology.

  • JCI and ISO accredited with eight consecutive years in the Newsweek global Top 10.
  • In-house CAR-T manufacturing through its GMP-certified Advanced Biotherapy Center (ABC).
  • Over 200 Sheba doctors are listed among Forbes' Top Doctors.
  • One of the few centers worldwide developing CAR-T therapies for severe autoimmune diseases.
  • Campus includes six major hospitals, among them the Leviev Heart Center and Edmond and Lily Safra Children's Hospital.

Payment & Rewards

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How it works: Step by step

Location
Derech Sheba 2, Ramat Gan, Israel

Why people love us

Our top offers for you

$8,000
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5.0
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